Wei Tong, PhD

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Wei Tong, PhD, is a member of the research faculty in the Division of Hematology at Children's Hospital of Philadelphia. She holds the Distinguished Chair in the Department of Pediatrics.  

Locations: Main Hospital
Appointments and Referrals: 1-800-TRY-CHOP (1-800-879-2467)

Education and Training

Fellowship

Postdoctoral fellow, Whitehead Institute for Biomedical Research, MIT, Cambridge, MA

Undergraduate Degree

BS in Molecular and Cellular Biology - University of Science and Technology of China

Graduate Degree

PhD in Developmental and Molecular Biology - Albert Einstein College of Medicine, New York, NY

Titles and Academic Titles

Researcher

Distinguished Chair in the Department of Pediatrics

Professor of Pediatrics, Perelman School of Medicine at the University of Pennsylvania

Departments and Services

Publications

Papers

2016

Cheng Ying, Chikwava Kudakwashe, Wu Chao, Zhang Haibing, Bhagat Anchit, Pei Dehua, Choi John K, Tong Wei: LNK/SH2B3 regulates IL-7 receptor signaling in normal and malignant B-progenitors. The Journal of clinical investigation 126(4): 1267-81, Apr 2016.

Cheng Ying, Chikwava Kudakwashe, Wu Chao, Zhang Haibing, Bhagat Anchit, Pei Dehua, Choi John K, Tong Wei: LNK/SH2B3 regulates IL-7 receptor signaling in normal and malignant B-progenitors. The Journal of clinical investigation 126(4): 1267-81, Apr 2016.

Giani Felix C, Fiorini Claudia, Wakabayashi Aoi, Ludwig Leif S, Salem Rany M, Jobaliya Chintan D, Regan Stephanie N, Ulirsch Jacob C, Liang Ge, Steinberg-Shemer Orna, Guo Michael H, Esko Tõnu, Tong Wei, Brugnara Carlo, Hirschhorn Joel N, Weiss Mitchell J, Zon Leonard I, Chou Stella T, French Deborah L, Musunuru Kiran, Sankaran Vijay G: Targeted Application of Human Genetic Variation Can Improve Red Blood Cell Production from Stem Cells. Cell stem cell 18(1): 73-8, Jan 2016.

2015

Jiang Qinqin, Paramasivam Manikandan, Aressy Bernadette, Wu Junmin, Bellani Marina, Tong Wei, Seidman Michael M, Greenberg Roger A: MERIT40 cooperates with BRCA2 to resolve DNA interstrand cross-links. Genes & development 29(18): 1955-68, Sep 2015.

Rozenova Krasimira, Jiang Jing, Donaghy Ryan, Aressy Bernadette, Greenberg Roger A, Tong Wei: MERIT40 deficiency expands hematopoietic stem cell pools by regulating thrombopoietin receptor signaling. Blood 125(11): 1730-8, Mar 2015.

2014

Song Yiwen, Jiang Jing, Vermeren Sonja, Tong Wei: ARAP3 functions in hematopoietic stem cells. PloS one 9(12): e116107, Dec 2014.

Abstracts

2014

Ying Cheng, Kudakwashe Chikwava, Chao Wu, Anchit Bhagat1, John K. Choi,  and Wei Tong: LNK (SH2B3) synergizes with TP53 in suppressing B-precursor Acute Lymphoblastic Leukemia through IL-7 Receptor signaling. American Society of Hematology (ASH) December 2014

Ying Cheng, Kudakwashe Chikwava, Chao Wu, Anchit Bhagat1, John K. Choi,  and Wei Tong: SH2B3 as a Novel Tumor Suppressor. Annual scientific meeting of the Society for Hematology and Stem Cells (ISEH)  August 2014.

Books

Chapters

Lodish HF, Ghaffari S., Socolovsky M, Tong, W., Zhang,  J.  : Intracellular Signaling by the Erythropoietin Receptor. "Erythropoiesis and Eythropoietins"  G Molineux, MA Foote, and SG Elliott. Birkhauser.  (eds.). Birkhäuser Publishing Ltd. Page: 155-174, 2009.

Tong, W. and Pollard, JW: Female Sex Steroid Hormone Regulation of Cell Proliferation in the Endometrium. "The Endometrium" Stanley R Glasser ,John D Aplin, Linda C Giudice and Siamak Tabizadeh (eds.). Taylor and Francis Publishers   Page: 94-109, 2002.

Posters and Presentations

Lectures by Invitation

2016

Tong W. Invited speaker at the Pathology Research Series, Northwestern University; 2016 Oct; Chicago, IL.

Tong W. Invited speaker at the Cardeza Seminar Series, Thomas Jefferson University; 2016 Apr; Philadelphia, PA.

2015

Tong W. Invited speaker at the Cardeza Seminar Series, Thomas Jefferson University; 2015 Dec; Philadelphia, PA.

Tong W. The 27th annual Fanconi Anemia Research Fund (FARF) meeting; 2015 Sep; Toronto, Canada.

Tong W. Invited speaker at the University of Columbia; 2015 May; New York, NY.

Tong W. Invited speaker at the University of Massachusetts Medical School at Worcester; 2015 May; Worcester, MA.

Awards and Honors

2014-2017, Innovation Award, Alex's Lemonade Stand Foundation (ALSF)

2014, Mentor for a Summer Undergraduate Internship Program in Translational and Clinical Research (CTSA) Trainee awardee

2014-2016, Innovation Award from Alex's Lemonade Stand Foundation (ALSF)

2013-2018, Scholar Award, Leukemia and Lymphoma Society (LLS)

2012-2015, Medical Research Award from the Gabrielle's Angel Foundation

2011, Mentor for a Summer Undergraduate Internship Program (SUIP) Trainee Awardee

2011-2013, Mentor for a Summer Undergraduate Internship Program (SUIP) Trainee Awardee

2010, Mentor for an American Society of Hematology (ASH) Research Trainee Awardee

2010-2011, Bingham Trust Pilot Award

2008-2010, Mentor for the American Heart Association (AHA) pre-postdoctoral fellows

2008-2015, Mentor for the American Heart Association (AHA) postdoctoral fellows

2008-2009, Mentor for the American Heart Association (AHA) postdoctoral fellows

2008-2009, Pilot award from PENN Institute for Regenerative Medicine (IRM)

2007-2008, McCabe Fellow Award

2005-2010, Howard Temin Career Development Award from National Cancer Institute (K01)

2001-2004, Postdoctoral fellowship from Damon Runyon Cancer Research Foundation

2001, Postdoctoral fellowship from Cancer Research Institute

1999, Sue Golding Graduate Division Award Lecture at "Julius Marmur" Graduate Symposium, Albert Einstein College of Medicine

1993-1994, Guanghua Scholarship in University of Science and Technology of China

1991-1993, People's Scholarship in University of Science and Technology of China

Editorial and Academic Positions

Editorial Positions

2015-present,  Reviewer, Oncotarget

2015-2018,  Editorial board, the Blood journal

2012-present,  Reviewer, Stem Cells and Development

2011-present,  Reviewer, Hematologica

2010-present,  Reviewer, Disease Models and Mechanisms

2009-present,  Reviewer, Experimental Hematology

2009-present,  Reviewer, Leukemia Research

2009-present, Reviewer, PLoS ONE

2009-present,  Reviewer, Proceedings of the National Academy of Sciences, USA

2008-present,  Reviewer, Stem Cells

2008-present,  Reviewer, Oncogene

2007-present,  Reviewer, The Journal of Clinical Investigation

2006-present,  Reviewer, Blood

Academic and Institutional Committees

2013-2015, Chair of the Preliminary Exam Committee for Cancer Biology, CAMB

2013-present, Course director, CAMB698 Spring

Leadership and Memberships

Memberships in Professional Organizations

International

2013-present, International Society for Hematology and Stem Cells (ISEH) 

2007-present, International Society for Stem Cell Research (ISSCR)

2004-present, American Society of Hematology (ASH)

National

2014-present, Ad hoc reviewer, NIH R01 Grant MCH study section

2011-present, Leukemia and Lymphoma Society (LLS) Career Development Program review committee