N. Scott Adzick, MD, MMM, FACS, FAAP

N. Scott Adzick, MD, is surgeon-in-chief of The Children's Hospital of Philadelphia and the founder and director of the Center for Fetal Diagnosis and Treatment.

Areas of Expertise: Clinical applications of fetal diagnosis and therapy, Endocrine surgery, Neonatal Surgery, Pectus surgery, Surgical treatment of hyperinsulinism, Thoracic Surgery, Thyroid and parathyroid surgery
Locations: Main Campus
Phone: 215-590-2730

  • Background

    Dr. Adzick is the C. Everett Koop Professor of Pediatric Surgery at CHOP and the founder and director of the Hospital’s Center for Fetal Diagnosis and Treatment. He also serves as CHOP’s Surgeon-in-Chief, Director of the Division of Pediatric General, Thoracic and Fetal Surgery, and Professor of Pediatrics, Obstetrics and Gynecology at the University of Pennsylvania School of Medicine.

    A true innovator in the field of fetal medicine since its inception, Dr. Adzick has dedicated his career to the pursuit of groundbreaking prenatal treatment for debilitating birth defects. He has made pioneering contributions to the practice of fetal surgery, and today continues to explore cutting edge surgical treatment options for life-threatening fetal anatomic malformations such as urethral obstruction, congenital diaphragmatic hernia, congenital cystic adenomatoid malformation of the lung, and sacrococcygeal teratoma.

    Dr. Adzick was the principal investigator for the National Institutes of Health (NIH) “Management of Myelomeningocele Study” (MOMS) at CHOP. This breakthrough study demonstrated that performing fetal surgery for spina bifida results in significantly improved outcomes versus conventional postnatal repair. The study represents the fruition of decades of research, much of it led by Dr. Adzick and his team, and is an example of how a once-radical idea can, through meticulous investigation, be transformed into a viable treatment for patients. Dr. Adzick is lead author of the study results, published in the New England Journal of Medicine.

    “For the first time in the history of mankind, we have a new way to offer hope to families who have a diagnosis of spina bifida,” says Dr. Adzick. “It’s very gratifying to take an idea we had 20 years ago, test it thoroughly, apply it cautiously in the clinical setting and, eventually, have the ability to offer a new therapy that can completely change the life of a child.”

    Dr. Adzick is also an active pediatric general and thoracic surgeon, and performs more than 400 operations a year. Much of his work is devoted to surgery in newborns including repairs for congenital diaphragmatic hernia, abdominal wall defects, lung lesions and other complex conditions affecting neonates.

    In addition, Dr. Adzick has a special interest and expertise in surgery for Hyperinsulinism (HI) and pediatric thyroid disorders. Working closely with CHOP’s Congenital Hyperinsulinism Center, he has been instrumental in using 18 F-DOPA PET scanning technology to identify focal HI lesions in the pancreas, offering the chance of a complete surgical cure by performing partial pancreatectomy for affected patients. Dr. Adzick is also one of the nation’s most experienced surgeons in pediatric surgery to treat thyroid cancer and Graves disease, working in collaboration with CHOP’s Pediatric Thyroid Center.

    Dr. Adzick earned his bachelor’s degree from Harvard College, his medical degree from Harvard Medical School, completed his surgical residency at Massachusetts General Hospital in Boston and his pediatric surgery fellowship at Boston Children’s Hospital. He holds a Masters of Medical Management degree from Carnegie Mellon University.

    Dr. Adzick was a postdoctoral scholar at the University of California San Francisco, where he was an attending surgeon from 1988 until 1995, when he was recruited to The Children’s Hospital of Philadelphia as Surgeon-in-Chief.

    Dr. Adzick has had NIH grant support for more than 30 years and has authored more than 500 peer-reviewed publications. He was elected to the Institute of Medicine of the National Academy of Science in 1998. He is recognized worldwide for his contributions to the field of pediatric surgery, and for his creative leadership at CHOP to enhance the surgical care of children. 

    To contact the Center for Fetal Diagnosis and Treatment, call 1-800-468-8376 (1-800-IN-UTERO).

  • Education and Training

    Medical School

    MD - Harvard Medical School, Boston, MA

    Internship

    Surgery - Massachusetts General Hospital, Boston, MA

    Residency

    Surgery - Massachusetts General Hospital, Boston, MA

    Fellowship

    Pediatric Surgery - Boston Children's Hospital, Boston, MA

    Additional Training

    Postdoctoral Scholar, Department of Surgery - University of California, San Francisco, CA

    Board Certification

    Pediatric Surgery
    Surgery
    Surgical critical care

    Undergraduate Degree

    Masters of Medical Management - Carnegie Mellon University, Pittsburgh, PA

  • Titles and Academic Titles

    Surgeon-in-Chief, Department of Surgery

    Chief, General, Thoracic and Fetal Surgery

    Director, Center for Fetal Diagnosis and Treatment

    C. Everett Koop Endowed Chair, Pediatric Surgery

    Professor of Pediatrics, Obstetrics and Gynecology, Perelman School of Medicine at the University of Pennsylvania

  • Conditions Treated
  • Centers and Programs
  • Publications

    Books

    Chapters

    2012

    Adzick NS, Farmer DL. Cysts of the lungs and mediastinum. In: Coran A, Adzick NS, Krummel TM, Laberge J-M, Shamberger RC, editors. Pediatric surgery, 7th ed. Philadelphia: Elsevier; 2012.

    Adzick NS. The pancreas. In: Coran A, Adzick NS, Krummel TM, Laberge J-M, Shamberger RC, editors. Pediatric surgery, 7th ed. Philadelphia: Elsevier; 2012.

    States LJ, Adzick NS. Localization of a focal lesion of congenital hyperinsulinism: Imaging and surgery. In: Stanley CJ, Shyng S, DeLeon D, editors. Monogenic hyperinsulinemic hypoglycemia disorders. Frontiers in diabetes series. Basel (Switzerland): S Karger AG; 2012.

    2011

    Danzer E, Rintoul NE, Adzick NS. Pathophysiology of neural tube defects. In: Polin RA, Fox WW, Abman SH, editors. Fetal and neonatal physiology, 4th ed. Philadelphia: Elsevier; 2011.

    Adzick NS. Congenital hyperinsulinism. In: Mattei PM, editor. Fundamentals of pediatric surgery, 2nd ed. Springer-Verlag; 2011. p. 611- 16.

    Mackenzie TC, Adzick NS. Perinatal diagnosis of surgical disease. In Puri P, editor. Newborn surgery, 3rd ed. Hodder Arnold; 2011. p. 46-59.

    Adzick NS. Forward. In: Rychik J, Tian Z, editors. Fetal cardiovascular imaging: Atlas and DVD. Philadelphia: Elsevier; 2011.

    Danzer E, Rintoul NE, Adzick NS. Pathophysiology of neural tube defects. In: Polin RA, Fox WW, Abman SH, editors. Fetal and neonatal physiology, 4th ed. Philadelphia: Elsevier; 2011. p. 1848-62.

    2009

    Adzick NS. Fetal thoracic lesions. In: Rodeck C, Whittle MJ, editors. Fetal medicine: Basic science and clinical practice, 2nd ed. Philadelphia: Elsevier; 2009. p. 429-36.

    2006 

    Adzick NS, Farmer DL. Cysts of the lungs and mediastinum. In: Grosfeld J, O’Neill J, Coran A, Fonkalsrud E, editors. Pediatric surgery, 6th ed. Philadelphia: Elsevier; 2006. p. 955-70.

    Bebbington MW, Johnson MP, Wilson RD, Adzick NS. Open fetal surgery. In: van Vugt JMG, Shulman LP, editors. Prenatal medicine. New York: Taylor & Francis; 2006. p. 501-16.

    Bruner JP, Wilson RD, Adzick NS, Wilkins-Haug L, Marshall AC, Quintero RA, et al. Intrauterine surgical techniques. In: Webster JG, editor. Encyclopedia of medical devices and instrumentation, 2nd ed. Hoboken: John Wiley & Sons; 2006. p. 171-81.

    Cass DL, Adzick NS. Fetal surgery - open - CCAM. In: Evans MI, editor. Prenatal diagnosis: Genetics, reproductive risks, testing, and management. Stamford: Appleton & Lange; 2006. p. 627-32.

    2005

    Adzick NS, Krupnick A. The pregnant patient. In: Mulholland M, Greenfield L, Lillemoe K, Oldham K, Zelenock G, editors. Surgery: Scientific principles and practice, 2nd ed. Philadelphia: Lippincott Williams, & Wilkins; 2005, p. 2116-33.

    2004

    Adzick NS. Conjoined twins. In: Martinez-Ferro, M, Cannizzaro C, Rodriguez S, Rabasa C, editors. Neonatologia quirurgica. 2004. p. 775-84.

    2003

    MacKenzie TC, Adzick NS. Surgical management of prenatally diagnosed malformations. In: Nyberg D, McGahan J, Pretorius D, Pilu G, editors. Diagnostic ultrasound of fetal anomalies, 2nd ed. Philadelphia: Lippincott Williams, & Wilkins; 2003. p. 1001-13.

    Walsh DS, Adzick NS. Fetal disorders and their prenatal management. In: Rudolph CD, Rudolph AM, Hostett MK, Lister G, Siegel NJ, editors. Rudolph’s pediatrics, 21st ed. New York: McGraw-Hill Medical; 2003. p. 77-9.

    Mackenzie TC, Adzick NS. Prenatal diagnosis of surgical diseases. In: Puri P, editor. Newborn surgery, 2nd ed. Oxford (UK): Heinemann Medical Books; 2003. p.15-23.

    Danzer E, Rintoul NE, Crombleholme TM, Adzick NS. Pathophysiology of neural tube defects. In: Polin RA, Fox WW, Abman SH, editors. Fetal and neonatal physiology, 3rd ed. Philadelphia: WB Saunders Company; 2003. p. 1771-84.

    Adzick NS. Fetal wound healing. In: Polin RA, Fox WW, Abman SH, editors. Fetal and neonatal physiology, 3rd ed. Philadelphia: WB Saunders Company; 2003. p. 1604-9.

    2002

    Cass DL, Adzick NS. Fetal wound healing implications. In: Katowitz JA, editor. Pediatric oculoplastic surgery. New York: Springer, 2002, p. 31-42.

    2001

    Adzick NS. The fetus with a lung lesion. In: Harrison MR, Evans M, Adzick NS, Holzgreve W, editors. The unborn patient: The art and science of fetal therapy, 3rd ed. Philadelphia: W.B. Saunders Co.; 2001. p. 287-96.

    Adzick NS, Harrison MR. Open fetal surgical techniques. In: Harrison MR, Evans M, Adzick NS, Holzgreve W, editors. The unborn patient: The art and science of fetal therapy, 3rd ed. Philadelphia: W.B. Saunders Co.; 2001.p. 247-58.

    Krupnick A, Adzick NS. Wound healing. In: Kreisel D, Krupnick AS, Kaiser LR, editors. The surgical review: An integrated basic and clinical science study guide. Philadelphia: Lippincott-Raven; 2001. p. 110-22.

    Krupnick A, Adzick NS. Burns. In: Kreisel D, Krupnick AS, Kaiser LR, editors. The surgical review: An integrated basic and clinical science study guide. Philadelphia: Lippincott-Raven; 2001. p. 123-38.

    Adzick NS, Krupnick A. Surgery in the pregnant patient. In: Greenfield L, Lillemoe K, Mulholland M, Oldham K, Zelenock G, editors. Surgery: Scientific principles and practice. Philadelphia: Lippincott Williams, & Wilkins; 2001. p. 2217-34.

    2000

    Lovvorn H, Adzick NS. Fetal obstructive uropathy. In: Pollack HM, McClennan BL, editors. Clinical urography. Philadelphia: WB Saunders Co.; 2000.

    1999

    Quinn TM, Adzick NS. Fetal surgery. In: Knobil E, Neill JD, editors. Encyclopedia of reproduction. Academic Press; 1999. p. 344-51.

    Cass DL, Adzick NS. Fetal cystic adenomatoid malformation. In: Rodeck C, Evans M, editors. Ultrasound and fetal therapy. New York: Parthenon Press; 1999. p. 49-60.

    1998

    Stern M, Longaker MT, Adzick NS, Kaban LB. Wound healing and regeneration in a fetal cleft lip model. In: Lynch SE, Genco RJ, Marx RE, editors. Tissue engineering. Chicago: Quintessence Publishing Co, Inc.; 1998. p. 55-70.

    Adzick NS. Fetal surgery. In: Taeusch W, Ballard RA, editors. Diseases of the newborn, 7th ed. Philadelphia: WB Saunders Co.;1998. p. 126-33.

    Yang E, Adzick NS. Fetal surgery. In: Burg FD, Ingelfinger JR, Wald ER, Polin RA, editors. Current pediatric therapy. Philadelphia: WB Saunders Co.; 1998. p. 361-68.

    Cass DL, Adzick NS. Fetal versus adult wound repair. In: Clark RAF, Davidson J, Mustoe T, Steed D, editors. Textbook of wound care. Philadelphia: WB Saunders Co.; 1998.

    1997

    Jennings RW, Adzick NS, Harrison MR. Fetal intervention for obstructive uropathy. In: O'Donnell BA, Koff SA, editor. Paediatric urology, 3rd ed. Surrey (England): Butterworth Scientific; 1997. p. 330-38.

    Duncan BW, Adzick NS. Prenatal diagnosis of surgical diseases. In Puri P, editor. Newborn surgery, 1st ed. Oxford (England): Heinemann Medical Books; 1997.  p. 15-25.

    Adzick NS. Fetal and neonatal wound healing. In: Polin R, Fox W, editors. Fetal and neonatal physiology, 2nd ed. Philadelphia: WB Saunders Co.; 1997. p. 2015-21.

    Adzick NS, Harrison MR. The fetus as patient. In: Oldham KT, Colombani PM, Foglia RP, editors. Surgery of infants and children: scientific principles and practice. Philadelphia: JB Lippincott Company; 1997.  p. 48-64.

    Adzick NS, Hedrick M. Other surgical conditions. In: Fisk NM, Moise KJ, editors. Fetal therapy: Invasive and transplacental. Cambridge (England): Cambridge University Press; 1997. p. 303-16.

    1996

    Jennings RW, Adzick NS, Harrison MR. Foetal surgery. In: Freeman NV, Atwell JD, Burge DM, Griffiths M, editors. Surgery of the newborn. London (England): Churchill Livingstone; 1996. p. 73-84.

    Adzick NS. Wound healing: biologic and clinical features. In: Sabiston DC, editor. Textbook of surgery: The biological basis of modern surgical practice, 15th ed. Philadelphia: WB Saunders Company; 1996. p. 207-20.

    Duncan BW, Adzick NS. Prenatal diagnosis of surgical diseases. In: Puri P, editor. Operative neonatal surgery. Oxford (England): Heinemann Medical Books; 1996. p.126-35.

    Cass DL, Adzick NS. Fetal wound healing renaissance. In: Hudson JW, editor. Oral and maxillofacial surgery clinics of North America. Philadelphia: Elsevier; 1996. 8:535-46.

    MacGillivray TE, Adzick NS, Harrison MR. The surgery of fetal malformations. In: Spitzer AB, editor. Intensive care of the fetus and neonate. St. Louis: CV Mosby Publishing Company; 1996. p. 190-98.

    1995

    Longaker MT, Harrison MR, Adzick NS. Fetal surgery. In: Morris P, Malt RA, editors. Oxford textbook of surgery. New York: Oxford University Press USA; 1995. p. 2001-5.

    Johnson MP, Harrison MR, Adzick NS, Reichler A, Evans MI. Fetal gene therapy. In: Rock J, Gant N, editors. Advances in obstetrics and gynecology. St. Louis: CV Mosby Publishing Company; 1994. p. 423-34.

    Estes JM, Adzick NS, Harrison MR. Antenatal open surgery for the abnormal fetus. In: Sabbagha RE, editor. Diagnostic ultrasound applied to obstetrics and gynecology, 3rd ed. Philadelphia: JB Lippincott Company; 1994. p. 557-68.

    deLorimier AA, Harrison MR, Adzick NS. Pediatric surgery. In: Way LW, editor. Current surgical therapy. Norwalk: Appleton-Lange; 1994. p. 1190-39.

    Lorenz HP, Adzick NS. Wound healing: The biological and clinical essentials. In: Sabiston DC, editor. Essentials of surgery. Philadelphia: WB Saunders Company; 1994. p. 86-90.

    Evans MI, Harrison MR, Adzick NS, Reichler A, Johnson MP. Surgical and medical interventions. In: Rock J, Gant N, editors. Advances in obstetrics and gynecology. St. Louis: CV Mosby Publishing Company; 1994. p. 401-22.

    1993

    Lorenz HP, Harrison MR, Adzick NS. Open fetal surgical interventions. In: Ludomirski A, editor. Therapeutic and diagnostic interventions in early life. Mt. Kisco: Futura Publishing Co.; 1993. p. 107-15.

    Harrison MR, Adzick NS, Flake AW. The prenatal management of the fetus with a correctable defect. In: Callen PW, editor. Ultrasonography in obstetrics and gynecology, 3rd ed. Philadelphia: WB Saunders Co.; 1993. p. 536-47.

    Estes JM, Adzick NS, Harrison MR. Fetoscopic surgery. In: Holcomb GW, editor. Pediatric endoscopic surgery. Norwalk: Appleton and Lange; 1993. p. 155-62.

    Adzick NS, Harrison MR. Fetal surgery. In: Copeland EM, Levine BA, Howard RJ, Sugerman H, Warshaw AL, editors. Current practice of surgery. New York: Churchill Livingstone Inc.; 1993. Section XVIII, p. 1-13.

    MacGillivray TE, Adzick NS. Lung transplantation in pediatrics. In: Lobe T, editor.  Surgical chest clinics of North America. Philadelphia: Elsevier; 1993. p. 569-82. 

    1992

    Adzick NS, Harrison MR. The fetus at surgery. In: Hobbins J, Mahoney J, Petrie R, Reece EA, editors. Medicine of the fetus and its mother. Philadelphia: JB Lippincott Company; 1992, p. 791-99.

    Jennings RW, Adzick NS, Harrison MR. Fetal intervention for obstructive uropathy. In: O'Donnell BA, Koff SA, editor. Paediatric urology, 2nd ed. Surrey (England): Butterworth Scientific; 1992. p. 48-62.

    Duncan BW, Adzick NS, Harrison MR. Fetal surgery. In: Iffy L, Apprizio J, Vintzileos A, editors. The textbook of operative obstetrics. New York: Pergamon Press; 1992. p 91-109.

    Harrison MR, Adzick NS. In utero surgical interventions. In: Ashcraft K, Holder T, editors. Pediatric surgery, 2nd ed. Philadelphia: W.B. Saunders; 1992. p. 1003-13.

    Adzick NS, Harrison MR. Antenatal open surgery for abnormal fetuses. In: Sabbagha RE, editor. Ultrasound applied to obstetrics and gynecology, 2nd ed. Philadelphia: JB Lippincott Co.; 1992. p. 366-75.

    Lorenz HP, Longaker MT, Adzick NS. Immunologic and infectious factors influencing wound repair. In: Fonkalsrud EW, Krummel TM, editors. Infections and immunologic disorders in pediatric surgery. Philadelphia: W.B. Saunders; 1992. p. 103-11.

    Adzick NS, Harrison MR. The fetal surgery experience. In: Adzick NS, Longaker Mt, editors. Fetal wound healing. New York: Elsevier Scientific; 1992. p. 1-24.

    Adzick NS, Longaker MT. Characteristics of fetal tissue repair. In: Adzick NS, Longaker MT, editors. Fetal wound healing. New York: Elsevier Scientific; 1992, p. 53-70.

    Adzick NS. Fetal animal and wound implant models. In: Adzick NS, Longaker MT, editors. Fetal wound healing. New York: Elsevier Scientific; 1992. p. 71-82.

    Lorenz HP, Longaker MT, Adzick NS. Human fetal skin: ontogeny and repair. In: Adzick NS, Longaker Mt, editors. Fetal wound healing. New York: Elsevier Scientific; 1992. p. 137-47.

    Longaker MT, Adzick NS, Ehrlich HP. Fetal wound contraction. In: Adzick NS, Longaker Mt, editors. Fetal wound healing. New York: Elsevier Scientific; 1992. p.149-60.

    Burd DAR, Longaker MT, Adzick NS. In vitro fetal wound healing. In: Adzick NS, Longaker Mt, editors. Fetal wound healing. New York: Elsevier Scientific; 1992. p. 255-64.

    Adzick NS, Longaker MT. Scarless fetal healing: therapeutic implications. In: Adzick NS, Longaker Mt, editors. Fetal wound healing. New York: Elsevier Scientific; 1992. p. 317-23.

    1991

    Jennings RW, Adzick NS, Harrison MR. Fetal surgery. In: Evans M, editor. Reproductive risks and prenatal diagnosis. Norwalk: Appleton and Lange; 1991. p. 311-20.

    Longaker MT, Adzick NS, Harrison MR. Perioperative management of the fetus undergoing surgery in utero. In: Diaz JH, editor. Perinatal anesthesia and intensive care. Philadelphia: WB Saunders; 1991.

    1990

    Adzick NS. Fetal cystic adenomatoid malformation of the lung. In: Harrison MR, Golbus MS, Filly RA, editors. The unborn patient, 2nd ed. Philadelphia: WB Saunders Company; 1990. p. 557-64.

    Adzick NS. Experimental pulmonary hypoplasia. In: Harrison MR, Golbus MS, Filly RA, editors. The unborn patient, 2nd ed. Philadelphia: WB Saunders Company; 1990. p. 320-7.

    Langer JC, Adzick NS. Surgical management of prenatally diagnosed malformations. In: Nyberg DA, Pretorius D, editors. An ultrasound atlas of fetal malformations. Chicago: Yearbook Medical Publishers; 1990. p. 725-39.

    Adzick NS, Harrison MR. Fetal surgery for congenital hydronephrosis. In: Quilligan EJ, Zuspan FP, editors. Current therapy in obstetrics and gynecology. Philadelphia: WB Saunders Co.; 1990. p. 333-38.

    deLorimier AA, Harrison MR, Adzick NS. Neuroblastoma. In: Crawford ED, Das S, editors. Current genitourinary cancer surgery. Philadelphia: Lea and Febiger; 1990, p. 407-28.

    deLorimier AA, Harrison MR, Adzick NS. Pediatric surgery. In: Way LW, editor. Current surgical therapy. Norwalk: Appleton-Lange; 1990. p. 1162-1206.

    Longaker MT, Adzick NS, Harrison MR. An update on the status of fetal surgery. In: Nyhus LM, editor. Surgery Annual, Vol. 23. Norwalk: Appleton-Century-Crofts; 1990. p. 53-68.

    1988

    Flake AW, Harrison MR, Adzick NS. Intrauterine intervention: Fetal surgery. In: Brans YW, Kuehl TJ, editors. Non-human primates in perinatal research, 1st ed. John Wiley and Sons; 1988. p. 245-62.

    Harrison MR, Adzick NS, Flake AW. The prenatal management of the fetus with a correctable defect. In: Callen PW, editor. Ultrasonography in obstetrics and gynecology, 2nd ed. Orlando: WB Saunders Co.; 1988. p. 364-74.

    Flake AW, Adzick NS, Glick PL, Harrison MR. Evaluation of the fetus with hydronephrosis. In: White RDW, Palmer JM, editor. New techniques in urology. New York: Futura Publishing; 1987.  p. 269-85.

    1987

    Harrison MR, Adzick NS. Experimental correction of diaphragmatic hernia. In: Sabbagha RE, editor. Diagnostic ultrasound applied to obstetrics and gynecology, 2nd ed. Philadelphia: J.B. Lippincott Co.; 1987. p. 438-48. 

    1986

    Adzick NS, Harrison MR. Fetal surgery in the nonhuman primate: Experimental models for fetal treatment. In: PW Nathanielsz, editor. Animal models in fetal medicine V. Ithaca, NY: Perinatology Press; 1986. p. 153-85.

    Adzick NS, Harrison MR. Surgical techniques in the fetal rabbit model. In: PW Nathanielsz, editor. Animal models in fetal medicine V. Ithaca, NY: Perinatology Press; 1986. p. 66-103.

    Papers

    2012

    Danzer E, Zarnow D, Gerdes M, D'Agostino JA, Siegle J, Bebbington MW, et al. Abnormal brain development and maturation on magnetic resonance imaging in survivors of severe congenital diaphragmatic hernia. J Pediatr Surg. 2012 Mar;47(3):453-61. Cited in PubMed; PMID:22424337. Read the abstract

    Danzer E, Johnson MP, Adzick NS. Fetal surgery for myelomeningocele: Progress and perspectives. Dev Med Child Neurol. 2012 Jan;54(1):8-14. doi: 10.1111/j.1469-8749.2011.04049.x. Epub 2011 Jul 11. Cited in PubMed; PMID 21745203. Read the abstract

    Laje P, Johnson MP, Howell LJ, Bebbington MW, Hedrick HL, Flake AW, et al. Ex utero intrapartum treatment in the management of giant cervical teratomas. J Pediatr Surg. 2012 Jun;47(6):1208-16. Cited in PubMed; PMID:22703795. Read the abstract

    2011

    Danzer E, Gerdes M, Bebbington MW, Koh J, Adzick NS, Johnson MP. Preschool neurobehavioral outcome following fetal myelomeningocele surgery. Fetal Diag Ther. 2011;30(3):174-9. Epub 2011 Sep 8. Cited in PubMed; PMID 21912086. Read the article

    Danzer E, Adzick NS. Fetal surgery for myelomeningocele: Patient selection, perioperative management and outcomes. Fetal Diagn Ther. 2011;30(3):163-73. Cited in PubMed; PMID 21849764. Read the abstract

    Adzick NS, Thom EA, Spong CY, Brock III JW, Burrows PK, Johnson MP, et al. A randomized trial of Prenatal versus postnatal repair of myelomeningocele. N Engl J Med. 2011 Mar 17;364(11):993-1004. Epub 2011 Feb 9. Cited in PubMed; PMID 21306277. Read the article

    Roybal JL, Moldenhauer JS, Khalek N, Bebbington MW, Johnson MP, Hedrick HL, et al. Early delivery as an alternative management strategy for selected high-risk fetal sacrococcygeal teratomas. J Pediatr Surg. 2011 Jul;46(7):1325-32. Cited in PubMed; PMID 21763829. Read the abstract

    Bebbington MW, Danzer E, Johnson MP, Adzick NS. Fetal surgery for myelomeningocele. Prenatal diagnosis. 2011 Jul;31(7):689-94. doi: 10.1002/pd.2805. Epub 2011 Jun 8.Cited in PubMed; PMID 21656790. Read the abstract

    Danzer E, Gerdes M, Bebbington MW, Koh J, Adzick SN, Johnson MP. Fetal myelomeningocele surgery: preschool functional status using the Functional Independence Measure for children (WeeFIM). Childs Nerv Syst. 2011 Jul;27(7):1083-8. Epub 2011 Feb 16. Cited in PubMed; PMID 21327591. Read the abstract

    Santore MT, Deans KJ, Behar BJ, Blinman TA, Adzick NS, Flake AW. Laparoscopic hepaticoduodenostomy versus open hepaticoduodenostomy for reconstruction after resection of choledochal cyst. J Laparoendosc Adv Surg Tech A. 2011 May;21(4):375-8. Epub 2011 Mar 28. Cited in PubMed; PMID 21443442. Read the abstract

    Grant RA, Heuer GG, Carrión GM, Adzick NS, Schwartz ES, Stein SC, et al. Morphometric analysis of posterior fossa after in utero myelomeningocele repair. J Neurosurg Pediatr. 2011 Apr;7(4):362-8. Cited in PubMed; PMID 21456906. Read the abstract

    Adzick NS, Thom EA, Spong CY, Brock JW 3rd, Burrows PK, Johnson MP, et al. A randomized trial of prenatal versus postnatal repair of myelomeningocele. N Engl J Med. 2011 Mar 17;364(11):993-1004. Epub 2011 Feb 9. Cited in PubMed; PMID 21306277. Read the article

    Danzer E, Zhang L, Radu A, Bebbington MW, Liechty KW, Adzick NS, et al. Amniotic fluid levels of glial fibrillary acidic protein in fetal rats with retinoic acid induced myelomeningocele: A potential marker for spinal cord injury. Am J Obstet Gynecol. 2011 Feb;204(2):178.e1-11. Cited in PubMed; PMID 21284970. Read the abstract

    Santore MT, Behar BJ, Blinman TA, Doolin EJ, Hedrick HL, Mattei P, et al. Hepaticoduodenostomy vs. hepaticojejunostomy for reconstruction after resection of choledochal cyst. J Pediatr Surg. 2011 Jan;46(1):209-13. Cited in PubMed; PMID 21238669. Read the abstract

    2010

    Danzer E, Finkel R, Gerdes M, Schwartz EM, Rintoul NN, Adzick NS, Johnson MP. The relationship of seizure activity and chronic epilepsy in early infancy and short-term neurodevelopmental outcome following fetal myelomeningocele closure. Neuropediatrics. 2010 Jun;41(3):140-3. Epub 2010 Sep 21. Cited in PubMed; PMID 20859834. Read the abstract

    Danzer E, Gerdes M, Bernbaum J, D'Agostino J, Bebbington MW, Siegle J, et al. Neurodevelopmental outcome of infants with congenital diaphragmatic hernia prospectively enrolled in an interdisciplinary follow-up program. J Pediatr Surg. 2010 Sep;45(9):1759-66. Cited in PubMed; PMID 20850617. Read the abstract

    Roybal JL, Liechty KW, Hedrick HL, Bebbington MW, Johnson MP, Coleman BG, et al. Predicting the severity of congenital high airway obstruction syndrome. J Pediatr Surg. 2010 Aug;45(8):1633-9. Cited in PubMed; PMID 20713212. Read the abstract.

    Danzer E, Layne MD, Auber F, Shegu S, Kreiger P, Radu A, et al. Gastroschisis in mice lacking aortic carboxypeptidase-like protein is associated with a defect in neuromuscular development of the eviscerated intestine.  Pediatr Res. 2010 Jul;68(1):23-8. Cited in PubMed; PMID 20386491. Read the abstract 

    Laje P, Stanley CA, Adzick NS. Intussusception after pancreatic surgery in children: A case series. J Pediatr Surg. 2010 Jul;45(7):1496-9. Cited in PubMed; PMID 20638531. Read the abstract

    Wilson RD, Lemerand K, Johnson MP, Flake AW, Bebbington M, Hedrick HL, et al. Reproductive outcomes in subsequent pregnancies after a pregnancy complicated by open maternal-fetal surgery (1996-2007). Am J Obstet Gynecol. 2010 May 27. Cited in PubMed; PMID 20537307. Read the abstract

    Danzer E, Gerdes M, Bebbington MW, Zarnow DM, Adzick NS, Johnson MP. Preschool neurodevelopmental outcome of children following fetal myelomeningocele closure. Am J Obstet Gynecol. 2010 May;202(5):450.e1-9. Epub 2010 Mar 29. Cited in PubMed; PMID 20347433. Read the abstract

    Danzer E, Gerdes M, D'Agostino JA, Bernbaum J, Siegle J, Hoffman C, et al. Prospective, interdisciplinary follow-up of children with prenatally diagnosed giant omphalocele: Short-term neurodevelopmental outcome. J Pediatr Surg. 2010 Apr;45(4):718-23. Cited in PubMed; PMID 20385277. Read the abstract

    2009

    Hüsler MR, Danzer E, Johnson MP, Bebbington M, Sutton L, Adzick NS, et al. Prenatal diagnosis and postnatal outcome of fetal spinal defects without Arnold-Chiari II malformation. Prenat Diagn. 2009 Nov;29(11):1050-7. Cited in PubMed; PMID: 19688779. Read the abstract

    Danzer E, Finkel RS, Rintoul NE, Bebbington MW, Schwartz ES, Zarnow DM, et al. Reversal of hindbrain herniation after maternal-fetal surgery for myelomeningocele subsequently impacts on brain stem function. Neuropediatrics. 2008 Dec;39(6):359-62. Epub 2009 Jun 30. Cited in PubMed; PMID: 19569004. Read the abstract

    Danzer E, Ernst LM, Rintoul NE, Johnson MP, Adzick NS, Flake AW. In utero meconium passage in fetuses and newborns with myelomeningocele. J Neurosurg Pediatr. 2009 Feb;3(2):141-6. Cited in PubMed; PMID: 19278315. Read the abstract

    Victoria T, Kramer SS, Markowitz R, Servaes S, Mong A, Jaramillo D, et al. Esophageal obstruction and intracardiac "mass" in association with omphalocele closure. J Pediatr Surg. 2009 Feb;44(2):448-50. Cited in PubMed; PMID19231555. Read the abstract

    Danzer E, Gerdes M, Bebbington MW, Sutton LN, Melchionni J, Adzick NS, et al. Lower extremity neuromotor function and short-term ambulatory potential following in utero myelomeningocele surgery. Fetal Diagn Ther. 2009;25(1):47-53. Epub 2009 Jan 28. Cited in PubMed; PMID 19174610. Read the abstract

    Wilson RD, Hedrick H, Flake AW, Johnson MP, Bebbington MW, Mann S, et al. Sacrococcygeal teratomas: Prenatal surveillance, growth and pregnancy outcome. Fetal Diagn Ther. 2009;25(1):15-20. Epub 2008 Dec 20. Cited in PubMed; PMID 19122459. Read the abstract

    Posters and Presentations

    2011

    Adzick, NS. Fetal surgery [lecture]. CHOP Faculty Luncheon Speaker Series; 2011 Dec 9; Philadelphia, PA.

    Adzick NS. Prenatal surgery for Spina Bifida-MOMS Trial [lecture]. Hot Topics in Neonatology; 2011 Dec 5; Washington, DC.

    Adzick NS. Fetal surgery: Then, now, next [lecture]. 10th World Congress of Perinatal Medicine; 2011 Nov 9; Punta del Este, Uruguay.

    Adzick NS. A breakthrough in fetal surgery: The MOMS Trial – an overview [lecture]. Advances in Neonatology, The Children’s Hospital of Philadelphia; 2011 Oct 27; Philadelphia, PA.

    Adzick NS. Fetal surgery for spina bifida: The birth of a breakthrough [lecture]. Jewish Federation of Greater Philadelphia; 2011 Oct 24; Philadelphia, PA.

    Adzick NS. Fetal surgery for spina bifida: Trials and tribulations [lecture]. Joint Surgery - Anesthesia Grand Rounds; Boston Children’s Hospital; 2011 Sept 28; Boston, MA.

    Adzick NS. Fetal surgery [lecture]. Massachusetts General Hospital Surgical Society; 2011 Sep 10; Boston, MA.

    Adzick NS. Fetal surgery [lecture]. Embryology course, University of Pennsylvania School of Medicine; 2011 Aug 31; Philadelphia, PA.

    Adzick NS. Meet the expert: Fetal surgery [lecture]. British Association of Pediatric Surgery; 2011 Jul 22; Belfast, Ireland.

    Adzick NS. Antenatal surgery for spina bifida [lecture]. Isabella Forshall Lecture, British Association of Paediatric Surgeons; 2011 Jul 21; Belfast, Ireland.

    Adzick NS. The MOMS Trial [keynote speaker]. Spina Bifida Association, National Conference; 2011 Jun 27; Anaheim, CA.

    Adzick NS. The MOMS Trial: Results and next steps [lecture]. 30th International Fetal Medicine and Surgery Society Meeting; 2011 May 16; Sedona, AZ.

    Adzick NS. Prenatal surgery for myelomeningocele: Patient selection, technique, care pathway, and lessons learned [lecture]. 30th International Fetal Medicine and Surgery Society Meeting; 2011 May 16; Sedona, AZ. 

    Adzick NS. Fetal myelomeningocele repair: The MOMS Trial [lecture]. Department of Anesthesiology and Critical Care Grand Rounds, The Children’s Hospital of Philadelphia; 2011 May 12; Philadelphia, PA.

    Adzick NS. Prenatal repair of myelomeningocele [lecture]. Philadelphia Perinatal Society; 2011 Apr 13; Philadelphia, PA.

    Adzick NS. The Center for Fetal Diagnosis and Treatment: 15 years of innovation; a historical perspective [lecture]. International Update on Prenatal Diagnosis and Treatment of Fetal Anomalies, Union League; 2011 Mar 16; Philadelphia, PA.

    Adzick NS. Prenatal repair of myelomeningocele [lecture]. International Update on Prenatal Diagnosis and Treatment of Fetal Anomalies, Union League; 2011 Mar 16; Philadelphia, PA.

    Adzick NS. Fetal myelomeningocele repair: Tribulations and trials [lecture]. Surgical Grand Rounds, The Children’s Hospital of Philadelphia; 2011 Feb 17; Philadelphia, PA .

    2010

    Adzick NS. Surgical management of congenital hyperinsulinism [lecture]. Neonatal Surgical Nurse Education Day, The Children’s Hospital of Philadelphia; 2011 Dec 3; Philadelphia, PA.

    Adzick NS. Fetal surgery [lecture]. Embryology Course, University of Pennsylvania School of Medicine; 2010 Sep 2; Philadelphia, PA.

    Adzick NS. A baby with congenital hyperinsulinism [lecture]. Surgical Grand Rounds, The Children’s Hospital of Philadelphia; 2010 Aug 19; Philadelphia, PA.

    Adzick NS. Update on fetal surgery [lecture]. Latest Developments in Obstetrical Management, Women’s Center at Presbyterian Hospital; 2010 May 8; Charlotte, NC.

    2009

    Adzick NS. Fetal surgery for lung lesions and for airway obstruction [lecture]. Spotlight on The Children’s Hospital of Philadelphia, An Overview of Pediatric Excellence From Before Birth Through Young Adulthood; 2009 Oct 8; Philadelphia, PA.

    Adzick NS. Fetal surgery [lecture]. Embryology Course, University of Pennsylvania School of Medicine; 2009 Sep 3; Philadelphia, PA.

  • Editorial and Academic Positions

    Editorial positions

    Editorial board

    2000-present, Current Problems in Surgery
    1997-present, Fetal Diagnosis and Therapy
    1993-present, Journal of Pediatric Surgery
    1993-present, Annals of Surgery

    Academic committees

    2003-2010, North American Fetal Therapy Network, Executive Committee