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Edward F Attiyeh, MD

Attending physician

Assistant professor of Pediatrics, Perelman School of Medicine at the University of Pennsylvania

Abstracts

2009

Lynch JE, Diskin SJ, Li H, Attiyeh EF, Maris JM, Mosse YP. Novel candidate neuroblastoma tumor suppressor genes, APOA1 and XPC, are identified in regions of recurrent copy number aberration following genome-wide methylation profiling [abstract]. Proceedings of the American Association for Cancer Research Annual Meeting; 2009 Apr; Denver, CO.

Diskin SJ, Cole K, Mosse YP, Sennett R, Lynch J, LaQuaglia M, et al. Identification of RAN as a neuroblastoma oncogene [abstract]. Proceedings of the American Association for Cancer Research Annual Meeting; 2009 Apr; Denver, CO.

Cole KA, Laquaglia MJ, Huggins J, Han MR, Attiyeh EF, Diskin SJ, et al. siRNA screen of the protein kinome identifies therapeutic targets in neuroblastoma [abstract]. Proceedings of the American Association for Cancer Research Annual Meeting; 2009 Apr; Denver, CO.

Attiyeh EF, Diskin SJ, Cole KA, Wood AC, Pecor KM, Lynch JE, et al. Integration of genomic data reveals the influence of copy number and methylation on gene expression [abstract]. Proceedings of the American Association for Cancer Research Annual Meeting; 2009 Apr; Denver, CO.

Awards

2006-2009, ASCO Foundation Career Development Award

2008, Advances in Neuroblastoma Research (ANR) Best Paper

2004-2008, William Guy Forbeck Research Foundation Scholar

2005-2007, Children's Neuroblastoma Cancer Foundation Award

2005-2007, AACR-Pennsylvania Department of Health Fellowship in Basic Cancer Research

2005-2006, ASCO Foundation Young Investigator Award

2005, ASCO Foundation Brigid Leventhal Merit Award

2005, ASCO Foundation Fellowship Merit Awardj

Books

Chapters

2008

Attiyeh EF: Rhabdomyosarcoma. In: Schwartz MW, editor. The 5-minute pediatric consult. Philadelphia: Lippincott Williams & Wilkins; 2008.

Attiyeh EF: Neuroblastoma. In: Schwartz MW, editor. The 5-minute pediatric consult. Philadelphia: Lippincott Williams & Wilkins; 2008.

Attiyeh EF: Ewing Sarcoma. In: Schwartz MW, editor. The 5-minute Pediatric Consult. Philadelphia: Lippincott Williams & Wilkins; 2008.

Editorial and Academic Positions

Editorial positions

2009-present, Peer-reviewer, BMC Cancer
2008-present, Peer-reviewer, Journal of Pediatric Hematology/Oncology
2006-present, Peer-reviewer, Pediatric Blood and Cancer

Academic positions

2006-present, Bi-monthly Oncology Resident Lecture Series, Solid Tumors, The Children's Hospital of Philadelphia

Leadership

Memberships in national organizations

2006-present, Children's Oncology Group (COG)
2005-present, BLAST Kids' Cancer, Scientific Advisor
2003-present, American Society of Clinical Oncology (ASCO)
2003-present, American Association for Cancer Research (AACR)
2002-present, American Society of Pediatric Hematology/Oncology (ASPHO)

Original Papers

2011

Nguyen le B, Diskin SJ, Capasso M, Wang K, Diamond MA, Glessner J, Kim C, et al. PLoS Genet. 2011 Mar;7(3):31002026. Epub 2011 Mar 17. Cited in PubMed: PMID 21436895. Read the article

Cole KA, Huggins J, Laquaglia M, Hulderman CE, Russell MR, Bosse K, et al. RNAi screen of the protein kinome identifies checkpoint kinase 1 (CHK1) as a therapeutic target in neuroblastoma. Proc Natl Acad Sci U S A. 2011 Feb 22;108(8):3336-41. Epub 2011 Feb 2. Cited in PubMed: PMID 21289283. Read the abstract

Wang K, Diskin SJ, Zhang H, Attiyeh EF, Winter C, Hou C, et al. Integrative genomics identifies LMO1 as a neuroblastoma oncogene. Nature. 2011 Jan 13;469(7329):216-20. Epub 2010 Dec 1. Cited in PubMed: PMID 21124317. Read the abstract

2009

Park JR, Villablanca JG, London WB, Gerbing RB, Haas-Kogan D, Adkins ES, et al. Outcome of high-risk stage 3 neuroblastoma with myeloablative therapy and 13-cis-retinoic acid: A report from the Children's Oncology Group. Pediatr Blood Cancer. 2009; 52(1): 44-50. Cited in PubMed: PMID 18937318. Read the article

Diskin SJ, Hou C, Glessner JT, Attiyeh EF, Laudenslager M, Bosse K, et al. Copy number variation at 1q21.1 associated with neuroblastoma. Nature. 2009 Jun 18;459(7249):987-91. Cited in PubMed: PMID 19536264. Read the article

Capasso M, Devoto M, Hou C, Asgharzadeh S, Glessner JT, Attiyeh EF, et al. Common variations in BARD1 influence susceptibility to high-risk neuroblastoma. Nature Genetics. 2009 Jun; 41(6): 718-723. Epub 2009 May 3. Cited in PubMed: PMID 19412175.  Read the article

Volchenboum SL, Li C, Li S, Attiyeh EF, Reynolds CP, Maris JM, et al. Comparison of primary neuroblastoma tumors and derivative early-passage cell lines using genome-wide single nucleotide polymorphism array analysis. Cancer Res. 2009 May; 69(10): 4143-9. Epub 2009 May 12. Cited in PubMed: PMID 19435921. Read the article

Teachey DT, Greiner R, Seif A, Attiyeh E, Bleesing J, Choi J, et al. Treatment with sirolimus results in complete responses in patients with autoimmune lymphoproliferative syndrome. Br J Haematol. 2009 Apr; 145(1): 101-6. Epub 2009 Feb 4. Cited in PubMed: PMID 19208097. Read the article

Attiyeh EF, Diskin SJ, Attiyeh MA, Mossé YP, Hou C, Jackson EM, et al. Genomic copy number determination in cancer cells from single nucleotide polymorphism microarrays based on quantitative genotyping corrected for aneuploidy. Genome research. 2009 Feb; 19(2): 276-83. Epub 2009 Jan 13. Read the article

Posters and Presentations

Attiyeh, EF. Genomic aberrations in neuroblastoma [invited lecture]. National Cancer Institute; 2009 Nov; Bethesda, MD.

Attiyeh, EF. Genetic aberrations in neuroblastoma [invited lecture]. University of Texas Southwestern Medical Center; 2009 Feb; Dallas, Texas.

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