Naomi J. Balamuth, MD

Naomi J. Balamuth, MD, is a pediatric oncologist at The Children's Hospital of Philadelphia. She has a special interest in pediatric sarcomas.

Areas of Expertise: Sarcoma therapy, Solid tumor cancers
Appointments and Referrals: 1-800-TRY-CHOP (1-800-879-2467)

  • Background

    My area of interest is in pediatric sarcomas, a subset of solid tumors. The majority of my time is spent in clinical care and improving our global approach to sarcomas. I am working on building up the sarcoma program at The Children's Hospital of Philadelphia to ensure we have a team approach to these complicated tumors in children, and to integrate the best new and established treatments for these patients.

    At Children's Hospital, we are first and foremost a family care center. I work to educate families and patients to understand the diagnosis and treatment plan so everyone is on the same page. I talk to families about the process and have them participate in the child's care. I also include the child in the discussion, in an age appropriate manner.

    We are creating a team structure at Children's Hospital to bring innovative treatment to our patients. Our sarcoma physicians and researchers meet frequently to ensure that each patient is receiving the latest and best treatment protocols. We also have hired our first nurse practitioner, who specializes in sarcomas.

    Children's Hospital has the unique capacity to take care of complicated patients with sarcomas. We have outstanding clinical care and a close relationship with our colleagues who are advancing our understanding and treatment of these challenging tumors.

  • Education and Training

    Medical School

    MD - Yale University, New Haven, CT


    The Children's Hospital of Philadelphia, PA


    The Children's Hospital of Philadelphia, PA


    The Children's Hospital of Philadelphia, PA

    Board Certification

    Pediatric Hematology-Oncology

    Undergraduate Degree

    Columbia University, NY

  • Titles and Academic Titles

    Attending Physician

    Assistant Professor of Clinical Pediatrics, Perelman School of Medicine at the University of Pennsylvania

  • Departments and Services
  • Publications




    Kazak AE, Alderfer MA, Rodriguez A. Psychological issues in cancer survival in pediatric populations. In Miller S, Bowen D, Croyle R, Rowland J, editors. Handbook of behavioral science and cancer. Washington, DC: American Psychological Association; 2008. p.449-65.

    Pentz RD, Haight AE, Noll RB, Barfield R, Pelletier W, Davies S, et al. The ethical justification for a minor sibling bone marrow donation: a case study. The Oncologist. 2008. p. 148-51.



    Balamuth NJ, Wood A, Wang Q, Jagannathan J, Mayes P, Zhang Z, et al. Serial transcriptome analysis and cross-species integration identifies centromere-associated protein E as a novel neuroblastoma target. Cancer Res. 2010 Apr 1;70(7):2749-58. Epub 2010 Mar 16. Cited in PubMed: PMID 20233875. Read the abstract

    Iyer R, Evans AE, Qi X, Ho R, Minturn JE, Zhao H, et al. Lestaurtinib enhances the antitumor efficacy of chemotherapy in murine xenograft models of neuroblastoma. Clinical cancer research : an official journal of the American Association for Cancer Research. Clin Cancer Res. 2010 Mar 1;16(5):1478-85. Epub 2010 Feb 23. Cited in PubMed: PMID 20179224. Read the article

    Balamuth N, Womer RB. Ewing’s sarcoma. Lancet Oncology 2010 Feb; 11(2): 184-192. Cited in PubMed: PMID 20152770. Read the abstract