Robert N. Baldassano, MD

Robert N. Baldassano, MD is co-director of the Center for Pediatric Inflammatory Bowel Disease at The Children's Hospital of Philadelphia.

Locations: Main Campus; CHOP Pediatric Care at Abington Memorial Hospital; Specialty Care, Abington
Appointments and Referrals: 1-800-TRY-CHOP

  • Education and Training

    Medical School

    MD - SUNY Health Science Center at Brooklyn, College of Medicine, Brooklyn, NY

    Residency

    Pediatrics - The Children's Hospital of Philadelphia, Philadelphia, PA

    Fellowship

    Pediatric Gastroenterology and Nutrition (clinical and research fellowships) - The Children's Hospital of Philadelphia

    Board Certification

    Diplomate, National Board of Medical Examiners
    Pediatric Gastroenterology and Nutrition
    Pediatrics

    Undergraduate Degree

    BS - State University at Albany, Albany, NY

  • Titles and Academic Titles

    Co-Director, Center for Pediatric Inflammatory Bowel Disease

    Colman Family Chair in Pediatric Inflammatory Bowel Disease, CHOP

    Professor of Pediatrics, Perelman School of Medicine at the University of Pennsylvania

  • Centers and Programs
  • Research Interests

    Pediatric inflammatory bowel disease

  • Publications

    Books

    Mamula P, Markowitz J, Baldassano RN (eds): Pediatric Inflammatory Bowel Disease. Pediatric Inflammatory Bowel Disease 2nd Edition. Mamula P, Markowitz J, Baldassano RN (eds.). Springer Science+Business Media, New York, NY, 2012.

    Mamula P, Markowitz J, Baldassano RN (eds): Pediatric Inflammatory Bowel Disease. Pediatric Inflammatory Bowel Disease. Mamula P, Markowitz J, Baldassano RN (eds.). Springer Science+Business Media, New York, NY, 2008.

    Chapters

    2013

    Albenberg L, Baldassano RN: What is the Current Understanding of the Etiology of Inflammatory Bowel Disease? Curbside Consultation in Pediatric GI: 49 Clinical Questions. Rosh J, Bousvaros A (eds.). Slack, Inc., Thorofare, NJ, 2013 Notes: in press.

    Albenberg L, Kelsen J, Baldassano RN: Pediatric Issues in Treating Ulcerative Colitis. Medical Therapy of Ulcerative Colitis. Lichtenstein GR (eds.). Springer, NY, 2013 Notes: In press.

    Grossman AB, Baldassano RN: Inflammatory Bowel Disease. Nelson Textbook of Pediatrics, 20th Edition. Kliegman R, Stanton B, St. Geme J, Schor N. (eds.). Elsevier, Inc., Philadelphia, PA, Chapter 328, 2013 Notes: submitted.

    Grossman AB, Baldassano RN.: Eosinophilic Gastroenteritis. Nelson Textbook of Pediatrics, 20th Edition. Kliegman R, Stanton B, St. Geme J, Schor N. (eds.). 2013 Notes: submitted.

    Kelsen J, Baldassano RN: Pediatric Considerations in Medical Therapy in Patients with Crohn's Disease. The Complete Guide to Medical Management, 2nd Edition. Lichtenstein GR (eds.). 2013 Notes: in press.

    2011

    Ghanem LR, Baldassano RN: Pediatric Considerations in Medical Therapy in Patients with Inflammatory Bowel Disease. Crohn's Disease: The Complete Guide to Medical Management. Lichtenstein GR (eds.). Slack, Inc., Thorofare, NJ, Apr 2011 Notes: Chapter 5.

    Ghanem LR, Baldassano RN: Pediatric Considerations in Medical Therapy in Patients with Inflammatory Bowel Disease. Ulcerative Colitis: The Complete Guide to Medical Management. Lichtenstein GR (eds.). Slack, Inc., Thorofare, NJ, Apr 2011 Notes: Chapter 5.

    Kelsen J, Hunter A, Baldassano RN: Pediatric Therapies in Inflammatory Bowel Disease. Advanced Therapy in Inflammatory Bowel Disease, 3rd Edition Vol 2: IBD and Crohn's Disease, Crohn's Disease Therapy. Bayless TM, Hanauer SB (eds.). People's Medical Publishing House-USA August 2011.

    Grossman AB and Baldassano RN: Eosinophilic Gastroenteritis. Nelson Textbook of Pediatrics, 19th Edition. Kliegman RM, Stanton BF, St. Geme JW, Schor NF, Behrman RE (eds.). Elsevier Saunders, Philadelphia, PA,(Chapter 329), 1304, 2011.

    Grossman AB and Baldassano RN: Inflammatory Bowel Disease. Nelson Textbook of Pediatrics, 19th Edition. Kliegman RM, Stanton BF, St. Geme JW, Schor NF, Behrman RE (eds.). Elsevier Saunders, Philadelphia, PA,(Chapter 328), 1294-1295, 2011.

    Grossman AB and Baldassano RN: Chronic Ulcerative Colitis. Nelson Textbook of Pediatrics, 19th Edition. Kliegman RM, Stanton BF, St. Geme JW, Schor NF, Behrman RE (eds.). Elsevier Saunders, Philadelphia, PA,(Chapter 328.1), 1295-1300, 2011.

    Grossman AB and Baldassano RN: Crohn Disease (Regional Enteritis, Regional Ileitis, Granulomatous Colitis). Nelson Textbook of Pediatrics, 19th Edition. Kliegman RM, Stanton BF, St. Geme JW, Schor NF, Behrman RE (eds.). Elsevier Saunders, Philadelphia, PA,(Chapter 328.2), 1300-1304, 2011.

    2008

    Grant SF, Baldassano RN, Hakonarson H: Classification of genetic profiles of Crohn's disease: a focus on the ATG16L1 gene. Expert Rev Mol Diagn 8(2): 199-207, Mar 2008.

    Jacobstein D, Baldassano RN: Crohn Disease. The 5-Minute Pediatric Consult, 5th Edition. Schwartz MW (eds.). Lippincott Williams & Wilkins, Philadelphia, PA, Page: 228-229, 2008.

    Jacobstein D, Baldassano RN: Inflammatory Bowel Disease. Pediatric Gastroenterology: The Requisites in Pediatrics. Liacouras CA, Piccoli DA (eds.). Mosby Elsevier, Philadelphia, PA, Page: 131-136, 2008.

    2007

    Kelsen J, Baldassano RN: Inflammatory Bowel Disease: The Difference between Children and Adults, Inflammatory Bowel Disease: Epidemiology, Pathogenesis, Diagnosis and Management 2007 Notes: Fiorcchi C, Katz J, Prantera C, Thomson A

    2006 

    Jacobstein D, Baldassano RN. Pediatric considerations in medical therapy in patients with ulcerative colitis and Crohn’s disease. In: Lichtenstein GR, editor. Inflammatory bowel disease: The complete guide to medical management. Philadelphia: Slack Inc.; 2006.

    2004

    Mamula P, Markowitz J, Baldassano RN. Clinical features and natural history of pediatric inflammatory bowel disease (Chapter 21). In: Sartor RB, Sandborn WJ, editors. Kirsner’s inflammatory bowel diseases. 6th ed. Philadelphia: Saunders Company; 2004. p. 301-315.

    Russo P, Brown K, Baldassano RN. Colitis in childhood (Chapter 5). In: Russo P, Rucchelli ED, Piccoli DA, editors. Pathology of pediatric gastrointestinal and liver disease. New York: Springer-Verlag Inc.; 2004. p. 100-127.

    2003

    Batres AL, Baldassano RN. Evaluation of the patient suspected of having inflammatory bowel disease (Chapter 16). In: Lichtenstein GR, editor. The clinical guide to inflammatory bowel disease. Thorofare: Slack Inc.; 2003. p. 315-324.

    Batres AL, Baldassano RN. Special considerations for the pediatric and adolescent patients with inflammatory bowel disease (Chapter 17). In: Lichtenstein GR, editor. The clinical guide to inflammatory bowel disease. Thorofare: Slack Inc.; 2003. p. 325-342.

    Mamula P, Markowitz J, Baldassano RN. Clinical features and natural history of pediatric inflammatory bowel disease In: Sandborn WJ, Sartor RB, editors. Kirsner’s inflammatory bowel disease. 6th ed. Philadelphia: Saunders Company; 2003.

    1999

    Baldassano RN. Crohn’s disease. In: Schwartz MW, editor. The 5-minute pediatric consult. 2nd ed. Baltimore: Williams & Wilkins; 1999. p. 290-291.

    Baldassano RN. Ulcerative colitis. In: Schwartz MW, editor. The 5-minute pediatric consult. 2nd ed. Baltimore: Williams & Wilkins; 1999. p. 846-847

    1997

    Baldassano RN. Inflammatory bowel disease. In: Schwartz MW, Curry TA, Sargent AJ, Blum NJ, Fein J, editors. Pediatric primary care: a problem-oriented approach. 3rd ed.  Philadelphia: Mosby-Year Book, Inc.; 1997. p. 543-547. 

    Kelsen J, Baldassano RN: Pediatric Considerations In Medical Therapy in Patients with Ulcerative Colitis. The Complete Guide to Medical Management, 2nd Edition. Lichtenstein GR (eds.). 2013 Notes: in press.

    Abstracts

    2013

    Baldassano RN, Colletti R, Cucchiara S, Dubinsky M, Escher J, Faubion W, Fell J, Gold B, Griffiths A, Hyams J, Koletzko S, Kugathasan S, Markowitz J, Ruemmele F, Veereman G, Callegari P, Molenda M, Tang KL, Wright R, Geldhof A, Winter H.: Serious infections and associated risk factors in patients receiving infliximab and immunotherapies for children with inflammatory bowel disease: DEVELOP Registry Data.   8th Congress of the European Crohn's and Colitis Organisation (ECCO), Vienna, Austria.  Feb 14-16 2013.

    Colletti R, Cucchiara S, Dubinsky M, Escher J, Faubion W, Fell J, Gold B, Griffiths A, Hyams J, Koletzko S, Kugathasan S, Winter H, Baldassano RN, Markowitz J, Ruemmele F, Callegari P, Goldhof A, Molenda M, Tang KL, Wright R, Veereman G. : Malignancies in children receiving infliximab and other inflammatory bowel disease therapies: An inflammatory bowel disease multicenter, prospective, long-term registry of pediatric patients (DEVELOP) registry data. Poster Presentation. 8th Congress of the European Crohn's and Colitis Organisation (ECCO), Vienna, Austria. Feb 14-16 2013.

    Albenberg L, Judge CP, Esipova TV, Sinha R, Bailey AG, Bittinger K, Grunberg S, Chen J, Bhopale VM, Baldassano RN, Lewis JD, Li H, Thom SR, Bushman FD, Vinogradov S, Wu GD.  : Biological oximetry using phosphorescence quenching reveals a dynamic oxygen equilibrium maintained between the gut microbiota and the host.  American Gastroenterological Association: Digestive Disease Week 2013, Orlando, FL, May 19-21, 2013. Gastroenterology 144(5; S1): S-156-157, May 2013.

    Baldassano RN, Colletti RB, Cucchiara S, Dubinsky M, Escher JC, Faubion WA, Fell J, Gold BD, Griffiths AM, Hyams JS, Koletzko S, Kugathasan S, Markowitz J, Ruemmele F, Veereman G, Callegari P, Geldhof A, Molenda MR, Wright R, Tang KL, Winter HS.: Serious infections and associated risk factors in patients receiving infliximab and immunotherapies for children with inflammatory bowel disease: DEVELOP Registry Data. American Gastroenterological Association:  American Gastroenterological Association; Digestive Disease Week 2013, Orlando, FL, May 19-21; Gastroenterology 144(5; S1): S-11, May 19-21 2013.

    Colletti RB, Cucchiara S, Dubinsky M, Escher JC, Faubion WA, Fell J, Gold BD, Griffths AM, Hyams JS, Koletzko S, Kugathasan S, Winter HS, Baldassano RN, Markowitz J, Ruemmele F, Callegari P, Geldhof A, Molenda MR, Tang KL, Wright R, Veereman G. : Malignancies in children receiving infliximab and other inflammatory bowel disease therapies: An inflammatory bowel disease multicenter, prospective, long-term registry of pediatric patients (DEVELOP) registry data.  American Gastroenterological Association: Digestive Disease Week 2013, Orlando, FL, May 19-21, 2013. Gastroenterology 144(5; S1): S-147, May  2013.

    Haberman Y, Jurickova I, Dexheimer PJ, Karns R, Tang D, Bonkowski EL, Fey B, Noe JD, Markowitz J, Heyman MB, Crandall W, Snapper SB, Kellermayer R, Kappelman M, Rosh JR, Otley AR, Pfefferkorn MD, Cohen SA, Patel AS, Kirschner BS, Baldassano RN, Dubinsky M, Walters TD, Aronow BJ, Denson L.  : Ileal RNA-Seq analyses reveal decreased mucosal myeloid cell immune responses in pediatric Crohn disease patients with phagocyte dysfunction due to neutralizing granulocyte macrophage colony stimulating factor (GM-CSF) auto-antibodies. Poster Presentation. American Gastroenterological Association: Digestive Disease Week 2013, Orlando, FL, May 19-21, 2013.  Gastroenterology 144(5; S1): S-708-709, May 2013.

    Hyams JS, Kim M, Denson L, Griffiths AM, Dubinsky M, Markowitz J, Baldassano RN, Crandall W, Rosh JR, Pfefferkorn MD, Otley AR, Heyman MB, Leleiko NS, Baker SS, Guthery SL, Evans J, Ziring D, Kellermayer R, Stephens MC, Mack DR, Oliva-Hemker M, Essers JB, Patel AS, Kirschner BS, Moulton E, Cohen SA, Liu C, Kugathasan S, Walters TD.: Early anti-TNFa therapy is superior to early immunomodulator therapy in newly diagnosed children with Crohn's disease. American Gastroenterological Association; Digestive Disease Week 2013, Orlando, FL, May 19-21, 2013. Gastroenterology  144(5; S1): S-146, May 2013.

    Kelsen JR, Posivak L, Pauly-Hubbard H, Baily AG, Bittinger K, Grunberg S, Baldassano RN, Lewis JD, Bushman FD, Wu GD. : Longitudinal characterization of the subgingival microbiota in pediatric Crohn's disease. Poster Presentation. American Gastroenterological Association: Digestive Disease Week 2013, Orlando, FL, May 19-21, 2013. Gastroenterology  144(5; S1): S-309-310, May 2013.

    Kugathasan S, Dubinsky M, Guthery SL, Okou DT, Bose P, Zwick ME, Cutler DJ, Waters JP, Hymans JS, Baldassano RN, Stephens MC, Heyman MB, Griffths AM, Crandall W, Markowitz J, Essers JB, Snapper SC, Walters TD, Aronow BJ, Denson L.: Early onset Crohn's disease exhibit distinct allele architecture differences and reveal new IBD loci.   American Gastroenterological Association; Digestive Disease Week 2013, Orlando, FL, May 19-21, 2013. Gastroenterology  144(5; S1): S-178, May 2013.

    Baldassano RN, Ruemmele F, Rosh J. Faubion WA, Kierkus J, Hyams JS, Lazar A, Wang Y, Eichner S, Thakkar RB. : Long-term safety of adalimumab in paediatric patients with Crohn's disease.  United European Gastroenterology (UEG) Week Berlin 2013, Berlin, Germany Oct 12-16 2013.Griffiths A, Baldassano RN, Walters T, Bronksy J, Hyams JS, Lazar A, Wang Y, Eichner S. Thakkar RB. : Improvement in markers of bone metabolism with adalimumab in children with moderately to severely active Crohn's disease: Results from Imagine 1.   United European Gastroenterology (UEG) Week Berlin 2013, Berlin, Germany Oct 12-16 2013.

    Kierkus J, Crandall W, Hyams JS, Rosh J, Markowitz J, Baldassano RN, Lazar A, Wang Y, Eichner S, Thakkar RB.: Early response to treatment with adalimumab in children with moderately to severely active Crohn's disease: Results from Imagine 1.   United European Gastroenterology (UEG) Week Berlin 2013, Berlin, Germany Oct 12-16 2013.

    2012

    Hyams J, Griffiths A, Markowitz J, Baldassano RN, Lazar A.: Induction and maintenance adalimumab therapy for the treatment of moderate to severe Crohn's disease in children. 2012 Canadian Digestive Diseases Week (CDDW), Montreal, Quebec, Canada. Feb 24-27 2012.

    Flint RA, Jarvis HW, Overton MH, Baldassano RN, Kim SC.: Characterization of mucosally-adherent Escherichia coli in pediatric inflammatory bowel disease patients. Poster Presentation. American Gastroenterological Assocation; Digestive Disease Week 2012. Gastroenterology 142(5; S1): S-373, May 2012.

    Hyams JS, Kim M, Denson L, Stephens MC, Markowitz J, Griffiths AM, Crandall W, Essers JB, Baldassano RN, Dubinsky M, Rosh JR, Pfefferson MD, Kim SC, Otley AR, Kellermayer R, Heyman MB, Leleiko NS, Baker SS, Guthery SL, Evans J, Ziring D, Kugathasan S, Walters TD.: Effect of deep ulceration at diagnostic colonoscopy on initial therapy and one year outcome in children with Crohn's disease. American Gastroenterological Assocation; Digestive Disease Week 2012. Gastroenterology 142(5; S1): S-36, May 2012.

    Overton M, Jarvis W, Flint R, Baldassano RN, Kim SC.: Quantification and characterization of Klebsiella pneumoniae in pediatric patients with inflammatory bowel disease. Poster Presentation. American Gastroenterological Association; Digestive Disease Week 2012. Gastroenterology 142(5; S1): S373-374, May 2012.

    Walters TD, Dubinsky M, Griffiths AM, Baldassano RN, Hyams JS, Stephens MC, Markowitz J, Crandall W, Heyman MB, Kellermayer R, Mack DR, Oliva-Hemker M, Patel AS, Kirschner BS, Moulton DE, Cohen SA, Aronow B, Denson L, Kugathasan S. : Anti-microbial serology patterns in 824 children with newly diagnosed Crohn's disease: Association with GM-CSF auto-antibodies and specific clinical phenotypes. American Gastroenterological Association; Digestive Disease Week 2012. Gastroenterology 142(5; S1): S36-37, May 2012.

    Albenberg L, Spengler C, Klink A, Mattei P, Baldassano RN, Mamula P, Kelsen JR.: Diverting ileostomy for the treatment of severe refractory indeterminate colitis. Poster Presentation. NASPGHAN Annual Meeting, Salt Lake City, UT. JPGN 55(S1): 203, Oct 2012.

    Gold BD, Kirschner BS, Cohen SA, O'Conner S, Heyman MH, Ferry GD, Baldassano RN, Garnett EA, Thompson AD, Tierney M, Yakrus MA, Winter HS. : Molecular analysis of Mycobacterium Avium Subspecies Paratuberculosis(MAP) in mucosal biopsies from treatment naïve children with IBD and controls Poster presentation. Poster Presentation. NASPGHAN Annual Meeting, Salt Lake City, UT. JPGN 55(S1): 205, Oct 2012.

    Judge CP, Albenberg LG, Esipova T, Grunberg S, Chen J, Li H, Baldassano RN, Lewis JD, Bushman FD, Vinogradov SA, Wu GD.: An oxygen equilibrium at the host-microbial interface determined by phosphorescent nanoprobe technology. Poster Presentation. NASPGHAN Annual Meeting, Salt Lake City, UT. JPGN 55(S1): 237, Oct 2012.

    Judge CP, Lee DY, Long J, Zemel BS, Baldassano RN, Leonard MB.: Children with Crohn disease continue to exhibit inflammatory cachexia despite advances in therapies. Poster Presentation. NASPGHAN Annual Meeting, Salt Lake City, UT. JPGN 55 (S1): 197, Oct 2012.

    Kaplan J, Bhasin M, Gold BD, Kirschner BS, Ward NL, Cohen SA, Heyman MB, Ferry GD, Baldassano RN, Moran CJ, Steven B, Garnett EA, Tierney MP, Drake L, Dowd SE, Cox SB, Mir SA, Kellermayer R, Libermann TA, Winter HS. : Ileal mucosa-associated microbiota changes in children with newly diagnosed, treatment-naïve Crohn's Disease. Poster Presentation. NASPGHAN Annual Meeting, Salt Lake City, UT. JPGN 55(S1): 205, Oct 2012.

    Kelsen JR, Posivak L, Grunberg S, Bailey A, Baldassano RN, Lewis J, Bushman F, Wu G.: The oral microbiome in pediatric Crohn Disease. Poster Presentation. NASPGHAN Annual Meeting, Salt Lake City, UT. JPGN 55(S1): 235, Oct 2012.

    Lee D, Kachelries KE, Gupta K, Lorusso M, Whitehead KM, Herskovitz RM, Leonard MB, Baldassano RN.: The impact of supplemental nasogastric tube nutrition on height and weight in pediatric Crohn's Disease. Poster of Distinction Award. NASPGHAN Annual Meeting, Salt Lake City, UT. JPGN 55(S1): 295, Oct 2012.

    Lee D, Kachelries KE, Gupta K, Lorusso M, Whithead KM, Herskovitz RM, Leonard MB, Baldassano RN. : The impact of supplemental nasogastric tube nutrition on height and weight in pediatric Crohn's disease. Poster Presentation. Food and Nutrition Conference and Expo (FNCE), Academy of Nutrition and Dietetics Annual Conference, Philadelphia, PA Oct 6-9 2012.

    Lee D, Lorusso M, Klink A, Gupta K, Martin A, Gilroy E, Nessel L, Otley A, Griffiths A, Lionetti P, Bushman F, Wu G, Baldassano RN, Lewis J.: Response to enteral nutritional therapy versus anti-TNFS in pediatric Crohn's Disease. Poster Presentation. NASPGHAN Annual Meeting, Salt Lake City, UT. JPGN 55(S1): 202, Oct 2012.

    Lorusso M, Lee D, Klink A, Gupta K, Martin A, Gilroy E, Nessel L, Otley A, Griffiths A, Lionetti P, Bushman F, Wu G, Lewis J, Baldassano RN. : Children with Crohn's Disease on 100% vs. 80% enteral nutritional therapy: Interim analysis of a prospective cohort study. Poster Presentation. NASPGHAN Annual Meeting, Salt Lake City, UT. JPGN 55(S1): 234, Oct 2012.

    Procopi T, Zimmerman A, Grossman A, Baldassano RN.: Infusion and post-infusion reactions to infliximab in pediatric inflammatory bowel disease patients. Poster Presentation. NASPGHAN Annual Meeting, Salt Lake City, UT. JPGN 55(S1): 227, Oct 2012.

    Zahm AM, Baldassano RN, Friedman J. : Rectal micro RNA levels are altered in pediatric ulcerative colitis. Poster Presentation. NASPGHAN Annual Meeting, Salt Lake City, UT. JPGN 55(S1): 217, Oct 2012.

    Cardinale CJ, Panossian S, Wang F, Frackelton EC, Kim CE, Mentch FD, Chiavacci RM, Kachelries KE, Pandey R, Grant SFA, Baldassano RN, Hakonarson H.: Targeted resequencing identifies secretion-defective variants of decoy receptor 3 in pediatric-onset inflammatory bowel disease. 62nd Annual Meeting of the American Society of Human Genetics, San Francisco, CA. Poster Presentation. Nov 6-10 2012.

    Kao C, Wei Z, Li J, Wang W, Glessner J, Cardinale C, Bradfield J, Frackelton E, Kim C, Mentch F, Qui H, Grant S, Baldassano RN, Hakonarson H and The International IBD Genetics Consortium: Pathway-based meta analysis of ulcerative colitis genome-wide association studies. 62nd Annual Meeting of the American Society of Human Genetics, San Francisco CA. Poster Presentation. Nov 6-10 2012.

    Pandey R, Cardinale CJ, Panossian S, Wang F, Frackelton E, Kim C, Mentch F, Chiavacci R, Kachelries K, Grant S, Baldassano RN, Hakonarson H.: Functional characterization of DcR3 and NF-kB in EBV transformed cell lines from IBD patients of different allelic background and role in disease pathogenesis 62nd Annual Meeting of the American Society of Human Genetics, San Francisco, CA. Poster Presentation. Nov 6-10 2012.

    Wei Z, Wang W, Bradfield J, Frackelton E, Kim C, Mentch F, Baldassano RN, Hakonarson H and The International IBD Genetics Consortium : Large-sample size, comprehensive catalog of variants and advanced machine learning technique boost risk prediction for inflammatory bowel disease. 62nd Annual Meeting of the American Society of Human Genetics, San Franciso, CA Nov 6-10 2012.

    Albenberg L, Judge C, Esipova T, Grunberg S, Chen J, Baldassano RN, Lewis J, Bushman F, Vinogradov S, Wu G. : An oxygen equilibrium at the host-microbial interface determined by phosporescent nanoprobe technology. Poster Presentation. 2012 Advances in Inflammatory Bowel Diseases: Crohn's & Colitis Foundation's National Clinical & Research Conference, Hollywood, FL, Dec 13-15, 2012. Inflamm Bowel Dis. 18(S)(12): S112,P-257, Dec 2012.

    Kelsen J, Posivak L, Bailey A, Grunberg S, Baldassano RN, Lewis J, Bushman F, Wu G.: The subgingival oral microbiome in pediatric patients with Crohn's Disease. 2012 Advances in Inflammatory Bowel Diseases: Crohn's & Colitis Foundation's National Clinical & Research Conference, Hollywood, FL, Dec 13-15,2012. Poster presentation. Inflamm Bowel Dis. 18(S)(12): S61,P-117, Dec 2012.

    Zahm A, Tsoucas D, Baldassano RN, Friedman J.: MicroRNA-regulated pathways in pediatric IBD. 2012 Advances in Inflammatory Bowel Diseases: Crohn's & Colitis Foundation's National and Clinical Research Conference, Hollywood, FL, Dec 13-15, 2012. Oral and Poster presentations. Inflamm Bowel Dis. 18(S)(12): S7,O-15 and S103,P-226, Dec 2012 Notes: Crohn's & Colitis Foundation's National Clinical & Research Conference, Hollywood, FL, Dec 13-15, 2012.

    2011

    Hyams J, Damaraju L, Blank M, Hohanns J, Guzo C, Winter H, et al. A randomized, multicenter, open-label phase 3 study to evaluate the safety and efficacy of infliximab in pediatric patients with moderate to severe ulcerative colitis [abstract}. 44th Annual Meeting of the European Society for Pediatric Gastroenterology, Hepatology and Nutrition; 2011 May 25-28; Sorento, Italy.

    Hyams JS, Griffiths A, Markowitz J, Baldassano RN, Faubion Jr. WA, Colletti RB, et al. Induction and maintenance adalimumab therapy for the treatment of moderate to severe Crohn's disease in children [abstract]. 6th Congress of the European Crohn's and Colitis Organization; 2011 Feb 24-26; Dublin, Ireland.

    Papers

    2013

    Prosnitz Aaron R, Leonard Mary B, Shults Justine, Zemel Babette S, Hollis Bruce W, Denson Lee A, Baldassano Robert N, Cohen Aaron B, Thayu Meena: Changes in vitamin D and parathyroid hormone metabolism in incident pediatric Crohn's disease. Inflamm Bowel Dis Jan 2013.

    Tsampalieros Anne, Lam Carol K L, Spencer Jenna C, Thayu Meena, Shults Justine, Zemel Babette S, Herskovitz Rita M, Baldassano Robert N, Leonard Mary B: Long Term Inflammation and Glucocorticoid Therapy Impair Skeletal Modeling during Growth in Childhood Crohn Disease. The Journal of Clinical Endocrinology and Metabolism May 2013 Notes: Epub ahead of print.

    Wei Zhi, Wang Wei, Bradfield Jonathan, Li Jin, Cardinale Christopher, Frackelton Edward, Kim Cecilia, Mentch Frank, Van Steen Kristel, Visscher Peter M, Baldassano Robert N, Hakonarson Hakon: Large Sample Size, Wide Variant Spectrum, and Advanced Machine-Learning Technique Boost Risk Prediction for Inflammatory Bowel Disease. American Journal of Human Genetics May 2013 Notes: Epub ahead of print.

    Gupta Kernika, Noble Angela, Kachelries Kelly E, Albenberg Lindsey, Kelsen Judith R, Grossman Andrew B, Baldassano Robert N: A novel enteral nutrition protocol for the treatment of pediatric Crohn's disease. Inflammatory Bowel Dis 19(7): 1374-8, Jun 2013.

    Baldassano RN, Griffth A, Mulberg A, Walters T.: The Future of Medical Therapy, additional section in "Discovering the Future of Pediatric IBD Care" J Pediatric Gastroenterol Nutr 2013 Notes: Accepted for publication.

    Boyle B, Kappelman M, Colletti R, Baldassano RN, Milov D, Crandall W.: Clinical effectiveness of thiopurines in maintaining remission in pediatric Crohn's disease. J Pediatric Gastroenterol Nutr 2013 Notes: Accepted for publication.

    Cardinale CJ, Baldassano RN.: Transcriptome profiling of human ulcerative colitis mucosa reveals altered expression of pathways enriched in genetic susceptibility loci (MI-13-206). Mucosal Immunology 2013 Notes: submitted.

    Cardinale CJ, Kelsen JR, Baldassano RN, Hakonarson H.: The impact of exome sequencing in inflammatory bowel disease. World Journal of Gastroenterology 2013 Notes: Accepted; published online.

    Cardinale CJ, Wei Z, Panossian S, Wang F, Kim CE, Mentch RD, Chiavacci RM, Kachelries KE, Pandey R, Grant SFA, Baldassano RN, Hakonarson H.: Targeted resequencing identifies defective variants of decoy receptor 3 in pediatric-onset inflammatory bowel disease. Genes and Immunity 2013 Notes: doi:10.1038/gene.2013.43.

    Crandall WV, Baldassano RN, Bousvaros A, Denson LA, Gupta N, Mackner LM.: Discovering the future of pediatric IBD care. J Pediatric Gastroenterol Nutr 2013 Notes: Accepted for publication.

    Klink AJ, Lee BK, Kelsen Jr, Albenberg LG, Robinson LF, Evans AA, Baldassano RN.: Treatment variation among children admitted with ulceratie colitis to US children's hospitals. Inflammatory Bowel Diseases 2013 Notes: submitted.

    2012

    Crandall Wallace V, Margolis Peter A, Kappelman Michael D, King Eileen C, Pratt Jesse M, Boyle Brendan M, Duffy Lynn F, Grunow John E, Kim Sandra C, Leibowitz Ian, Schoen Bess T, Colletti Richard B: Improved outcomes in a quality improvement collaborative for pediatric inflammatory bowel disease. Pediatrics 129(4): e1030-41, Apr 2012.

    Gray Wendy N, Denson Lee A, Baldassano Robert N, Hommel Kevin A: Treatment adherence in adolescents with inflammatory bowel disease: the collective impact of barriers to adherence and anxiety/depressive symptoms. Journal of Pediatric Psychology 37(3): 282-91, Apr 2012.

    Hyams Jeffrey, Damaraju Lakshmi, Blank Marion, Johanns Jewel, Guzzo Cynthia, Winter Harland S, Kugathasan Subra, Cohen Stanley, Markowitz James, Escher Johanna C, Veereman-Wauters Gigi, Crandall Wallace, Baldassano Robert, Griffiths Anne: Induction and maintenance therapy with infliximab for children with moderate to severe ulcerative colitis. Clinical Gastroenterology and Hepatology: The official clinical practice journal of the American Gastroenterological Association 10(4): 391-9.e1, Apr 2012.

    Yatsunenko Tanya, Rey Federico E, Manary Mark J, Trehan Indi, Dominguez-Bello Maria Gloria, Contreras Monica, Magris Magda, Hidalgo Glida, Baldassano Robert N, Anokhin Andrey P, Heath Andrew C, Warner Barbara, Reeder Jens, Kuczynski Justin, Caporaso J Gregory, Lozupone Catherine A, Lauber Christian, Clemente Jose Carlos, Knights Dan, Knight Rob, Gordon Jeffrey I: Human gut microbiome viewed across age and geography. Nature 486(7402): 222-7, Jun 2012.

    Hyams Jeffrey S, Griffiths Anne, Markowitz James, Baldassano Robert N, Faubion William A, Colletti Richard B, Dubinsky Marla, Kierkus Jaroslaw, Rosh Joel, Wang Yaqin, Huang Bidan, Bittle Barry, Marshall Michael, Lazar Andreas: Safety and Efficacy of Adalimumab for Moderate to Severe Crohn's Disease in Children. Gastroenterology Aug 2012.

    Horton DB, Sherry DD, Baldassano RN, Weiss PF. : Enthesitis is an extraintestinal manifestation of inflammatory bowel disease. Ann Paediatr Rheum 1(4): 214-221, 2012.

    2011

    Gray WN, Denson LA, Baldassano RN, Hommel KA. Treatment adherence in adolescents with inflammatory bowel disease: the collective impact of barriers to adherence and anxiety/depressive symptoms. J Pediatr Psychol. Epub 2011 Nov 10. Cited in PubMed; PMID 22080456. Read the abstract

    Gray WN, Denson LA, Baldassano RN, Hommel KA. Disease activity, behavioral dysfunction, and health-related quality of life in adolescents with inflammatory bowel disease. Inflamm Bowel Dis. 2011 Jul;17(7):1581-6. doi: 10.1002/ibd.21520. Epub 2010 Nov 4. Cited in PubMed; PMID 21674715. Read the abstract

    Hommel KA, Denson LA, Baldassano RN. Oral medication adherence and disease severity in pediatric inflammatory bowel disease. Eur J Gastroenterol Hepatol. 2011 Mar;23(3):250-4. Cited in PubMed; PMID 21304318. Read the abstract

    Odell S, Sander E, Denson LA, Baldassano RN, Hommel KA. The contributions of child behavioral functioning and parent distress to family functioning in pediatric inflammatory bowel disease. J Clin Psychol Med Settings. 2011 Mar;18(1):39-45. Cited in PubMed; PMID 21359503. Read the abstract 

    Herzer M, Denson LA, Baldassano RN, Hommel KA. Patient and parent psychosocial factors associated with health-related quality of life in pediatric inflammatory bowel disease. J Pediatr Gastroenterol Nutr. 2011 Mar;52(3):295-9. Cited in PubMed; PMID 21295708. Read the abstract 

    Guilfoyle SM, Denson LA, Baldassano RN, Hommel KA. Paediatric parenting stress in inflammatory bowel disease: application of the Pediatric Inventory for Parents. Child Care Health Dev. Epub 2011 Feb 7. doi: 10.1111/j.1365-2214.2010.01200.x. Cited in PubMed; PMID 21299591. Read the abstract

    Anderson CA, Boucher G, Lees CW, Franke A, D'Amato M, Taylor KD, et al. Meta-analysis identifies 29 additional ulcerative colitis risk loci, increasing the number of confirmed associations to 47. Nat Genet. 2011 Mar;43(3):246-52. Epub 2011 Feb 6. Erratum in: Nat Genet. 2011 Sep;43(9):919. Cited in PubMed; PMID 21297633. Read the article

    Hommel KA, Odell S, Sander E, Baldassano RN, Barg FK. Treatment adherence in paediatric inflammatory bowel disease: perceptions from adolescent patients and their families. Health Soc Care Community. 2011 Jan;19(1):80-8. doi: 10.1111/j.1365-2524.2010.00951.x. Epub 2010 Sep 9. Cited in PubMed; PMID 21143544. Read the abstract

    Kelsen JR, Kim J, Latta D, Smathers S, McGowan KL, Zaoutis T, et al. Recurrence rate of clostridium difficile infection in hospitalized pediatric patients with inflammatory bowel disease. Inflamm Bowel Dis. 2011 Jan;17(1):50-5. doi: 10:1002/ibd.21421. Epub 2010 Aug 18. Cited in PubMed; PMID 20711068. Read the abstract

    Rossin EJ, Lage K, Raychaudhuri S, Xavier RJ, Tatar D, Benita Y, et al. Proteins encoded in genomic regions associated with immune-mediated disease physically interact and suggest underlying biology. PLoS Genet. 2011 Jan 13;7(1):31001273. Cited in PubMed; PMID 21249183. Read the article 

    2010

    Gray WN, Denson LA, Baldassano RN, Hommel KA. Disease activity, behavioral dysfunction, and health-related quality of life in adolescents with inflammatory bowel disease. Inflamm Bowel Dis. Epub 2010 Nov 4. Cited in PubMed; PMID 21053329. Read the article

    Hommel KA, Baldassano RN. Brief report: barriers to treatment adherence in pediatric inflammatory bowel disease. J Pediatr Psychol. 2010 Oct;35(9):1005-10. Epub 2009 Dec 21. Cited in PubMed; PMID 20026567. Read the article 

    Thayu M, Denson LA, Shults J, Zemel BS, Burnham JM, Baldassano RN, et al. Determinants of changes in linear growth and body composition in incident pediatric Crohn's disease. Gastroenterology. 2010 Aug;139(2):430-8. Epub 2010 Apr 22. Cited in PubMed; PMID 20417635. Read the article

    Gupta N, Bostrom AG, Kirschner BS, Ferry GD, Gold BD, Cohen SA, et al. Incidence of structuring and penetrating complications of Crohn’s disease diagnosed in pediatric patients. Inflamm Bowel Dis. 16(4)638-44, Apr 2010. Read the abstract

    Kelsen JR, Rosh J, Heyman M, Winter HS, Ferry G, Cohen S, et al. Phase I trial of sargramostim in pediatric Crohn's disease. Inflamm Bowel Dis. 2010 Jul; 16(7):1203-8. Cited in PubMed; PMID 20052780. Read the article

    Posters and Presentations

    2014

    International Scientific Committee, 3rd International Symposium on Pediatric Inflammatory Bowel Disease (PIBD 2014) 
Rotterdam, The Netherlands

    2013

    Organizer, The Joint CHOP-PENN Nutrition, Obesity, and Metabolomics at the Clinical Interface Symposium 
Philadelphia, PA

    Moderator and Organizer: Growing Up with IBD: A Forum for Parents and Children with Inflammatory Bowel Disease, The Children's Hospital of Philadelphia, Pediatric Education Day 
Philadelphia, PA

    Chair, Publication Committee, A Multicenter, Prospective, Long-Term, Observational Registry of Pediatric Patients with Inflammatory Bowel Disease (DEVELOP). 
International

    Co-Moderator, "Current Controversies in Pediatric IBD; Debate: How Should We Monitor, Prevent, and Treat Osteoporosis in IBD?" 2013 Advances in Inflammatory Bowel Diseases, Crohn's & Colitis Foundation's Clinical & Research Conference 
Hollywood, FL

    Co-Moderator, "Challenges in Treating Pediatric IBD", 2013 Advances in Inflammatory Bowel Diseases, Crohn's & Colitis Foundation's Clinical & Research Conference. 
Hollywood, FL

    2012

    Moderator and Organizer: Growing Up with IBD: A Forum for Parents and Children with Inflammatory Bowel Disease, The Children's Hospital of Philadelphia, Pediatric Education Day 
Philadelphia, PA

    Co-Moderator: Pediatric Gastroenterology: Clinical and Translational 1, Digestive Disease Week 2012 
San Diego, CA

    Co-Moderator: "The Road Ahead: Priority Areas for Future Research & Quality Improvement Work", Single Topic Symposium: Discovering the Future of Pediatric Inflammatory Bowel Disease Care, Annual Meeting, North American Society of Pediatric Gastroenterology, Hepatology and Nutrition 
Salt Lake City, UT

    Organizing and Steering Committee, Single Topic Symposium: "Discovering the Future of Pediatric Inflammatory Bowel Disease Care", North American Society of Pediatric Gastroenterology, Hepatology and Nutrition 
Salt Lake City, UT

    Meet the Professor: "Ulcerative Colitis: Challenging Cases", Annual Meeting, North American Society of Pediatric Gastroenterology, Hepatology and Nutrition 
Salt Lake City, UT

    Organizing Committee: 2012 Advances in Inflammatory Bowel Diseases: Crohn's & Colitis Foundation's Clinical & Research Conference 
Hollywood, FL

    2011

    Baldassano RN. Genetics, diet and the microbiome in IBD [presentation]. Frontiers in Pediatric Gastroenterology, Simches Research Center, Massachusetts General Hospital; 2011 Jun; Boston, MA.

    Baldassano RN. Unveiling the complex etiology of inflammatory bowel disease [presentation]. Grand Rounds, The Children's Hospital of Philadelphia; 2011 May; Philadelphia, PA.

    Grossman A, Procopi T, Piccoli DA, Baldassano RN. ImproveCareNow: a quality improvement collaborative for pediatric inflammatory bowel disease [poster presentation]. First Annual Patient Safety and Quality Day, The Children's Hospital of Philadelphia; 2011 May 26; Philadelphia, PA.

    Baldassano RN. What role does enteral nutrition have in therapy? [presentation]. Great Debates and Updates in Inflammatory Bowel Disease; 2011 Apr; New York, NY.

    Baldassano RN. Inflammatory bowel disease in the new decade [presentation]. Samuel Morrison Lecture, Geisinger Clinic; 2011 April Danville, PA.

    Baldassano RN. Nutritional therapy in inflammatory bowel disease [presentation]. Therapeutic Options: What's New, The Seventh Penn Inflammatory Bowel Disease Symposium; 2011 Mar; Philadelphia, PA.

    Baldassano RN. Biologics and beyond [presentation]. The 6th Annual Pediatric IBD Academic Workshop; 2011 Mar; Las Vegas, NV.

    Baldassano RN. IBD in the new decade [presentation]. Growing Up With IBD: A Forum for Parents and Children with Inflammatory Bowel Disease, The Children's  Hospital of Philadelphia Pediatric Education Day; 2011 Feb; Philadelphia, PA.

    2010

    Baldassano RN. Enteral therapy: where should this be in our treatment algorithm? [presentation]. Current Topics in Pediatric IBD; 2010 Advances in Inflammatory Bowel Diseases; Crohn's & Colitis Foundation Clinical and Research Conference; 2010 Dec; Hollywood, FL.

    Baldassano RN. What is the role of biologics in the therapy of pediatric IBD? [presentation]. Controversies and Challenges in Pediatric IBD; 2010 Advances in Inflammatory Bowel Diseases; Crohn's & Colitis Foundation Clinical and Research Conference; 2010 Dec; Hollywood, FL.

    Baldassano RN. Stump the panel: cases for presentation and discussion with participants [panel participant]. 2010 Advances in Inflammatory Bowel Diseases; Crohn's & Colitis Foundation Clinical and Research Conference; 2010 Dec; Hollywood, FL.

    Baldassano RN. IBD in the new decade [presentation]. Patient and Family Education Conference, Crohn's & Colitis Foundation of America, Houston Gulf Coast/South Texas Chapter; 2010 Nov; Houston, TX.

    Hunter AK, Zhang Z, Kerbowski T, Rappaport E, Baldassano RN, deZoeten E. Beyond GWAS: evaluation of methylation and gene expression in pediatric Crohn disease [poster presentation]. North American Society of Pediatric Gastroenterology, Hepatology and Nutrition. 2010 Oct 21-24; New Orleans, LA.

    Gupta K, Noble A, Baldassano RN, Sreedharan R, et al. A novel enteral nutritional therapy protocol for the treatment of pediatric Crohn's disease [poster presentation]. North American Society of Pediatric Gastroenterology, Hepatology and Nutrition; 2010 Oct 21-24; New Orleans, LA.

    Boyle B, Kappelman M, Colletti R, Qureshi MA, Baldassano RN, Milov D, et al. Clinical effectiveness of thiopurines in maintaining remission for pediatric Crohn's disease [poster presentation]. North American Society of Pediatric Gastroenterology, Hepatology and Nutrition; 2010 Oct 21-24; New Orleans, LA.

    Baldassano RN. Genetic research: is it important? [presentation]. Growing Up With IBD: A Forum for Parents and Children With Inflammatory Bowel Disease, The Children's Hospital of Philadelphia; 2010 Feb; Philadelphia, PA.

    Baldassano RN. Genetics and IBD [presentation]. Growing Up With IBD: A Forum for Parents and Children With Inflammatory Bowel Disease, The Children's Hospital of Philadelphia; 2010 Feb; Philadelphia, PA.

  • Awards and Honors

    2013, Fellows Faculty Honor Roll
    2012, Blockley-Osler Award
    2003, Pediatric Resident Teaching Honor Roll
    2003-2008, Best Doctors in America
    2003-2012, America's Top Doctors
    2002, Best Pediatricians in America, Best Doctors List
    2002, Physician of the Year Award
    2001, Doctors Who Make a Difference, Child Magazine
    2001, David Cornfeld Bedside Teaching Award
    2001-2013, Top Doctors for Kids, Philadelphia Magazine,
    1993, Education Award for Excellence in Inflammatory Bowel Disease Teaching, Research and Clinical Care
    1992, Golden Apple Award for Excellence in Pediatric Resident Teaching
    1990-1993, Crohn's and Colitis Foundation of American Research Fellowship Award
    1988, Pediatric Housestaff Humanitarian Award
    1988, NIH Research Fellowship Award
    1984-1985, Honor Scholarship, SUNY Health Science Center
    1983-1987, Alpha Omega Alpha-SUNY Health Science Center
    1975-1977, Mathematical Association of American, Mathematics Honor Society
    1975-1977, Summa Cum Laude-State University of New York
    1975-1977, Phi Beta Kappa-State University of New York
    1975-1977, Sigma Phi Sigma, Physics Honor Society-State University of New York

  • Editorial and Academic Positions

    Editorial positions

    2006-present, Editorial Advisory Board, Gastroenterology and Hepatology
    2003-present, Reviewer, Clinical Gastroenterology and Hepatology
    2002-present, Section Editor, Inflammatory Bowel Disease
    2001-present, Medical Editor, emedicine: PEDIATRICS, Medical Textbook for Health Professionals and Consumers
    1997-present, Reviewer, Journal of Parenteral and Enteral Nutrition
    1996-present, Reviewer, Journal of Pediatric Gastroenterology and Nutrition

    Academic committees

    2012-present, Resident Search Committee, The Children's Hospital of Philadelphia
    2001-present, Target TNF, Evolving the Course of Inflammatory Bowel Disease Therapy, International Round Table, Barcelona, Spain
    1998-present, General Pediatrics Search Committee, The Children's Hospital of Philadelphia
    1997-present, Physician Compensation Committee, The Children's Hospital of Philadelphia

  • Leaderships

    Memberships in professional organizations

    American Academy of Pediatrics
    American Gastroenterological Association
    Crohn's and Colitis Foundation of America
    International Consortium of Pediatric IBD Centers
    North American Society for Pediatric Gastroenterology, Hepatology and Nutrition
    World Congress of Pediatric Gastroenterology, Hepatology and Nutrition