Antonella Cianferoni, MD, PhD

Locations: Specialty Care, Market Street; Specialty Care & Surgery Center, King of Prussia, S. Goddard Blvd.
Appointments and Referrals: 1-800-TRY-CHOP (1-800-879-2467)

  • Education and Training

    Medical School

    MD - University of Florence, Florence, Italy


    Pediatrics - The Children's Hospital of Philadelphia, Philadelphia, PA


    Allergy and Immunology - Boston Children's Hospital and Brigham and Women Hospital, Boston, MA

    Board Certification


    Graduate Degree

    PhD in Pediatric Immunology - University of Florence, Florence, Italy

  • Titles and Academic Titles

    Attending Physician

    Assistant Professor of Pediatrics, Perelman School of Medicine at the University of Pennsylvania

  • Departments and Services
  • Publications


    Novembre E., Cianferoni A. Anafilassi (trans: Anaphylaxis). Chapter 20 in: “Emergenze pediatriche” (trans: Paediatric Critical Care) A. Sarti-P. Busoni Editor, Pacini ed.  Ospaedaletto (Pi), 1997: pp299-304

    Novembre E., Cianferoni A., Vierucci A. L’immunoterapia specifica nel trattamento delle allergopatie respiratorie (trans: Specific immunotherapy in respiratory diseases treatment) 1998 Pisa:Chapter 3;pp353-358

    Cianferoni A, Vierucci A La tosse nel bambino (trans. Cough in children) Chapter 13 in Allergologia Pediatrica- A. Vierucci   Selecta Medica ed. 2003

    Vierucci A, Cianferoni A: La Tosse nel bambino (trans: Cough in children) 2005 Gentili ed, Pisa, Italy

    Novembre E, Cianferoni A: Uricaria In children in press





    Cianferoni A., Schroeder J.T., Vierucci A., Lichtenstein L.M., Georas S.N., Casolaro V. Differential Effects of Salicylates on IL-4 and IL-2 Expression in Human CD4+ T Lymphocytes. J Allergy Clin Immunol 1999;103 (2):922

    Schroeder J.T., Cianferoni A., Lichtenstein L.M., Casolaro V. Enhanced secretion of IL-4 by human basophils following pre-treatment with Sodium Salicylate and Aspirin. J Allergy Clin Immunol 1999;103 (2):737

    Valapour M., Cianferoni A., Cumberland J., Burke T., Seto E., Casolaro V., Georas S. Histone deacetylation inhibits Interlukin-4 (IL-4) gene expression. Am J Resp Crit Care Med, 1999;159

    Cianferoni A., Schroeder JT, Clancy Keen J., Schmidt J.W., Georas S.N., Casolaro V. Dissociation of the effects of salicylates on IL-4 gene expression and NFAT activation in human T cell. J Allergy Clin Immunol 2000; 105 (p2):485

    Florio G., Cianferoni A.,  Clancy Keen J., Schmidt J.W., Lakenan WA, Georas S.N., Casolaro V. NF-kB-dependent transcription of the IL-13 gene in activated T cells J Allergy Clin Immunol 2000;105 (p2):817

    Novembre E., Cianferoni A., Lombardi E., Bernardini R., Favilli T., Pucci N., Brizzi I., Vierucci A. Significance of skin prick test reactivity and total serum IgE level in a group of children with atopic dermatitis seen at age 2 and at age 11. ERS

    Keen J.C., Natarajan S. , Burke T., Guo J., Cianferoni A., Schmidt J., Casolaro V. Distinct signal requirements for IL-4 and IL-13 expression. cells J Allergy Clin Immunol J Allergy Clin Immunol 2001:107:489

    Schroeder J.T., Miura K., Cianferoni A., Kim H.H., Roche E.M., Sin A.Z., Casolaro V. Nuclear Factor of Activated T Cell (NFAT) Expression in Human Basophils: Evidence for NFAT2 Involvement in IgE-mediated IL-4 Generation. J Allergy Clin Immunol 2001:107:1006

    Cianferoni A., Novembre E., Lombardi E., Bernardini R., Mugnaini L., Pucci N., Vierucci A. Clinical features of severe acute anaphylaxis in patients admitted to an UniversityHospital: an 11 year retrospective review (1985-1996) J Allergy Clin Immunol 2001:107:197

    Cianferoni A, Novembre E, Pucci N, Lombardi E, Bernardini R, Vierucci A. Clinical features of anaphylaxis in children: 7 years follow up of 46 cases. J Allergy Clin Immunol 2003:111:127

    Cianferoni A, Ramesh N, Gallego MD, Geha RS. Wiskott-Aldrich protein (WASP) is important for NAFT and AP1 activation. J Allergy Clin Immunol 2004

    Cianferoni A, Scott J, Bonilla FA, Dioun A, Gellis S, Geha R, Schneider L. Bilateral lower leg swelling and lymphocytic panniculitis in a patient with XLA. J Clinical Immunology  2005



    Poliak N, Elias M, Cianferoni A, Treat J. Acute generalized exanthematous pustulosis: the first pediatric case caused by a contrast agent. Ann Allergy Asthma Immunol. 2010 Sep;105(3):242-3. No abstract available.




    Rothenberg ME, Spergel JM, Sherrill JD, Annaiah K, Martin LJ, Cianferoni A, Gober L, Kim C, Glessner J, Frackelton E, Thomas K, Blanchard C, Liacouras C, Verma R, Aceves S, Collins MH, Brown-Whitehorn T, Putnam PE, Franciosi JP, Chiavacci RM, Grant SF, Abonia JP, Sleiman PM, Hakonarson H. Common variants at 5q22 associate with pediatric eosinophilic esophagitis. Nat Genet. 2010 Apr;42(4):289-91. Epub 2010 Mar 7. Read abstract.




    Cianferoni A, Spergel JM. Food allergy: review, classification and diagnosis. Allergol Int. 2009 Dec;58(4):457-66. Epub 2009 Oct 25. Review. Read abstract.




    Cianferoni A, Schneider L, Schantz PM, Brown D, Fox LM. Visceral larva migrans associated with earthworm ingestion: clinical evolution in an adolescent patient. Pediatrics. 2006 Feb;117(2):e336-9. Read abstract.

  • Editorial and Academic Positions
    • Johns Hopkins University PhD student teaching in lab during their rotation/electives
    • Boston Children’s Hospital teaching to residents during their rotation in allergy and immunology
    • Boston Children’s Hospital PhD student teaching in lab during their rotation/electives