Nicholas F. Evageliou, MD

Nicholas F. Evageliou, MD, is an attending physician at CHOP’s Cancer Center with a special interest in treating solid tumors in children.

Areas of Expertise: Neuroblastoma
Locations: Specialty Care & Surgery Center, Voorhees
Appointments and Referrals: 1-800-TRY-CHOP

  • Background

    I provide care for a broad range of hematology and oncology conditions in our suburban clinic in Voorhees, New Jersey. Our patients benefit from a small, approachable and welcoming clinic in a suburban setting that also is linked to the world-class medical expertise, clinical research and state-of-the-art facilities at Children's Hospital in Philadelphia.

    A prominent part of pediatric care is being able to interact with families -- as well as to communicate on an age-appropriate level to patients. Our team spends a significant amount of time answering questions and explaining complicated treatments.

    My specific interest is in solid tumors and neuroblastoma in particular. Neuroblastoma is often a very aggressive tumor that affects young children. My specific research is related to the effect of molecules called polyamines on neuroblastoma growth -- and how the molecules can be manipulated to treat this cancer. Depriving cells of polyamines shows promise in the treatment of certain cancers.

    I hope to be able to translate this research into a clinical application that will help young patients with neuroblastoma and other solid tumors.

     

     

  • Education and Training

    Medical School

    University of Connecticut School of Medicine, Farmington, Conn.

    Internship

    Children's Hospital of Philadelphia, Philadelphia, Pa.

    Residency

    Children's Hospital of Philadelphia, Philadelphia, Pa.

    Fellowship

    Children's Hospital of Philadelphia, Philadelphia, Pa.

    Board Certification

    American Board of Pediatrics

  • Titles and Academic Titles

    Attending Physician

  • Centers and Programs
  • Research Interests

    Neuroblastoma & Polyamines

  • Publications

    Books

    Chapters

    Wallis E, Evageliou N. Neuroblastoma. In: Florin T, Ludwig S, editors. Netter's pediatrics. Philadelphia: Saunders Elsevier; 2011.

    Papers

    2009

    Evageliou N, Michael Hogarty. Disrupting polyamine homeostasis as a therapeutic strategy for neuroblastoma. Clin Cancer Res. 2009 Oct 1;15(19):5956-61. Read the article

    Posters and Presentations

    2009

    Evageliou N. A phase I of DFMO (D,L-difluoromethylornithine) in combination with ironotecan and temozolamide in patients with relapsed and refractory high-risk neuroblastoma [presentation]. AACR/ASCO Vail Methods in Clinical Cancer Research Workshop; 2009 Aug; Vail, CO.

    Evageliou N. Dual targeting of AMD1 and ODC1 potently inhibits neuroblastoma initiation in vitro and in vivo [presentation]. American Association for Cancer Research; 2009 Apr; Denver, CO.

    Evageliou N. Dual targeting of AMD1 and ODC1 potently inhibits neuroblastoma initiation in vitro and in vivo [presentation]. American Society of Pediatric Hematology and Oncology (ASPHO); 2009 Apr; San Diego, CA.