Matthew Gillespie, MD

Matthew Gillespie, MD, is an attending cardiologist with expertise in interventional cardiology and transcatheter treatment of heart disease.

Areas of Expertise: Interventional cardiology, Transcatheter treatment of heart disease
Locations: Main Campus
Phone: 215-590-4040

  • Education and Training

    Medical School

    MD - Temple University School of Medicine, Philadelphia, PA

    Internship

    Pediatrics - The Children's Hospital of Philadelphia, Philadelphia, PA

    Residency

    Pediatrics - The Children's Hospital of Philadelphia, Philadelphia, PA

    Fellowship

    Pediatric Cardiology - The Children's Hospital of Philadelphia, Philadelphia, PA

    Board Certification

    Pediatric Cardiology
    Pediatrics

  • Titles and Academic Titles

    Attending Cardiologist

    Assistant Professor of Pediatrics, Perelman School of Medicine at the University of Pennsylvania

  • Centers and Programs
  • Publications

    Books

    Chapters

    2006

    Gillespie MJ, Schneider H, Rome JJ. The use of cardiac catheterization to diagnose and treat heart disease in pediatric patients. In: Vetter VL, editor.  The pequisites in pediatrics - pediatric cardiology.  Philadelphia: Elsevier Mosby; 2006.  p. 195 - 221.

    Abstracts

    2011

    Shyam K Sathanandam, Andrew C Glatz, Diana Geisser, Yoav Dori, David J Goldberg, Matthew J Gillespie, et al. Impact of pressure recovery on Doppler estimates of pressure gradient across aortic valve in infants and children: correlation of Doppler- and catheter-derived indices for isolated valvar aortic stenosis [abstract]. American Heart Association Scientific Sessions; 2011 Nov 12-16; Orlando, FL.

    Shuto T, Kondo N, Dori Y, Koomalsingh KJ, Gorman JH III, Gorman RC, et al. Percutaneous transvenous Melody valve-in-ring procedure for mitral valve replacement [abstract]. EACTS 25th Annual Meeting; 2011 Oct 1-5; Lisbon, Portugal.

    Koomalsingh K, Akers JE, Merrill DR, Shuto T, Kondo N, Gorman JH III, Gorman RC, et al. Localized cooling device for myocardial tissue salvage [abstract]. ASME 2011 Bioengineering Conference; 2011 Jun 22-25; Farmington, PA.

    Robb JD, Harris MA, Minakawa M, Koomalsingh K, Rodriguez E, Shuto T, et al. Melody® valve implantation into the branch pulmonary arteries for treatment of pulmonary insufficiency in an ovine model of right ventricular outflow tract dysfunction following Tetralogy of Fallot repair [abstract]. The Society for Heart Valve Disease 6th Biennial Meeting; 2011 Jun 25-28; Barcelona, Spain.

    2010

    Harris MA, Whitehead KK, Gillespie MJ, Liu TI, Cosulich MT, Shin DC, et al. Differential branch pulmonary artery fraction is a function of differential pulmonary vascular resistance and pulmonary arterial properties [abstract]. American Heart Association Scientific Sessions; 2010 Nov 13-17; Chicago, IL.

    Whitehead KK, Doddasomayajula R, Harris MA, Glatz AC, Gillespie MJ, Rome JJ, et al. Semi-quantitative estimation of systemic to pulmonary collateral flow in patients with superior cavopulmonary connections using magnetic resonance angiography during lower extremity gadolinium injection: correlation with direct flow measurement [abstract]. American Heart Association Scientific Sessions; 2010 Nov 13-17; Chicago, IL.

    Robb JD, Harris MA, Minakawa M, Rodriguez E, Koomalsingh KJ, Shuto, et al. Bilateral branch pulmonary artery Melody® valve implantation reduces pulmonary regurgitation in an ovine model of postoperative Tetralogy of Fallot [abstract]. American Heart Association Scientific Sessions; 2010 Nov 13-17; Chicago, IL.

    Glatz AC, Rome JJ, Fogel MA, Gillespie MJ, Harris MA, Whitehead KK. Pulmonary blood flow is systematically underestimated at cardiac catheterization in single ventricle patients after superior cavo-pulmonary connection due to the presence of systemic-pulmonary collateral flow [abstract]. American Heart Association Scientific Sessions; 2010 Nov 13-17; Chicago, IL.

    Glatz AC, Patel A, Zhu X, Dori Y, Hanna BD, Gillespie MJ, et al. Radiation exposure from diagnostic and interventional cases in a modern, large-volume pediatric cardiac catheterization laboratory [abstract]. American Heart Association Scientific Sessions; 2010 Nov 13-17; Chicago, IL.

    Schwartz M, Glatz AC, Rome JJ, Gillespie MJ. The Amplatzer Vascular Plug and Amplatzer Vascular Plug II for vascular occlusion procedures in 50 patients with congenital cardiovascular disease [abstract]. The Society for Cardiovascular Angiography and Interventions 33rd Annual Scientific Sessions; 2010 May 5-8; San Diego, CA.

    Papers

    2012

    Patel AR, Farrell P, Harris M, Gaynor JW, Gillespie MJ. Acquired ventricular septal aneurysm in a patient with pulmonary atresia with intact ventricular septum. Cardiol Young. 2012 Apr;22(2):227-9. Epub 2011 Aug 25. Cited in PubMed; PMID 21864450. Read the abstract

    Kondo N, Shuto T, McGarvey JR, Koomalsingh KJ, Takebe M, Gorman RC, et al. Melody valve-in-ring procedure for mitral valve replacement: feasibility in four annuloplasty types. Ann Thorac Surg. 2012 Mar;93(3):783-8. Cited in PubMed; PMID 22364973. Read the abstract

    Schwartz MC, Rome JJ, Gillespie MJ, Whitehead K, Harris MA, Fogel MA, et al. Relation of left ventricular end diastolic pressure to right ventricular end diastolic volume after operative treatment of tetralogy of fallot. Am J Cardiol. 2012 Feb 1;109(3):417-22. Epub 2011 Nov 11. Cited in PubMed; PMID 22078963. Read the abstract

    Glatz AC, Rome JJ, Small AJ, Gillespie MJ, Dori Y, Harris MA, et al. Systemic to pulmonary collateral flow as measured by cardiac magnetic resonance imaging is associated with acute post-Fontan clinical outcomes. Circ Cardiovasc Imaging. Epub 2012 Jan 6. Cited in PubMed; PMID 22228054. Read the abstract

    2011

    Hicks JD, Donsante A, Pierson TM, Gillespie MJ, Chou DE, Kaler SG. Increased frequency of congenital heart defects in Menkes disease. Clin Dysmorphol. Epub 2011 Nov 29. Cited in PubMed; PMID 22134099. Read the abstract

    Shuto T, Kondo N, Dori Y, Koomalsingh KJ, Glatz AC, Rome JJ, et al. Percutaneous transvenous Melody valve-in-ring procedure for mitral valve replacement. J Am Coll Cardiol. 2011 Dec 6;58(24):2475-80. Cited in PubMed; PMID 22133846. Read the abstract

    Vergnat M, Jackson BM, Cheung AT, Weiss SJ, Ratcliffe SJ, Gillespie MJ, et al. Saddle-shape annuloplasty increases mitral leaflet coaptation after repair for flail posterior leaflet. Ann Thorac Surg. 2011 Sep;92(3):797-803. Epub 2011 Jul 30. Cited in PubMed; PMID 21803330. Read the abstract

    Gillespie MJ, Dori Y, Harris MA, Sathanandam S, Glatz AC, Rome JJ. Bilateral branch pulmonary artery melody valve implantation for treatment of complex right ventricular outflow tract dysfunction in a high-risk patient. Circ Cardiovasc Interv. 2011 Aug;4(4):e21-3. Cited in PubMed; PMID 21846891. No abstract available.

    Banka P, Sleeper LA, Atz AM, Cowley CG, Gallagheher D, Gillespie MJ, et al. Practice variability and outcomes of coil embolization of aortopulmonary collaterals before Fontan completion: a report from the Pediatric Heart Network Fontan Cross-Sectional Study. Am Heart J. 2011 Jul;162(1):125-30. Cited in PubMed; PMID 21742098. Read the abstract

    Harris MA, Whitehead KK, Gillespie MJ, Liu TY, Cosulich MT, Shin DC, et al. Differential branch pulmonary artery regurgitant fraction is a function of differential pulmonary arterial anatomy and pulmonary vascular resistance. JACC Cardiovasc Imaging. 2011 May;4(5):506-13. Cited in PubMed; PMID 21565739. Read the abstract

    Dori Y, Sarmiento M, Glatz AC, Gillespie MJ, Jones VM, Harris MA, et al.  X-ray magnetic resonance fusion to internal markers and utility in congenital heart disease catheterization. Circ Cardiovasc Imaging. 2011 Jul;4(4):415-24. Epub 2011 May 2. Cited in PubMed; PMID 21536785. Read the abstract

    O'Connor MJ, Ravishankar C, Ballweg JA, Gillespie MJ, Gaynor JW, Tabbutt S, et al. Early systemic-to-pulmonary artery shunt intervention in neonates with congenital heart disease. J Thorac Cardiovasc Surg. 2011 Jul;142(1):106-12. Epub 2011 Jan 26. Cited in PubMed; PMID 21272898. Read the abstract

    Robb JD, Harris MA, Minakawa M, Rodriguez E, Koomalsingh KJ, Shuto T, et al. Melody valve implantation into the branch pulmonary arteries for treatment of pulmonary insufficiency in an ovine model of right ventricular outflow tract dysfunction following tetralogy of Fallot repair. Circ Cardiovasc Interv. 2011 Feb 1;4(1):80-7. Epub 2011 Jan 4. Cited in PubMed; PMID 21205938. Read the article

    2010

    Glatz AC, Zhu X, Gillespie MJ, Hanna BD, Rome JJ. Use of angiographic CT imaging in the cardiac catheterization laboratory for congenital heart disease. JACC Cardiovasc Imaging. 2010 Nov;3(11):1149-57. Cited in PubMed; PMID 21071003. Read the abstract

    Matsuzaki K, Morita M, Hamamoto H, Noma M, Robb JD, Gillespie MJ, et al. Elimination of ischemic mitral regurgitation does not alter long-term left ventricular remodeling in the ovine model. Ann Thorac Surg. 2010 Sep;90(3):788-94. Cited in PubMed; PMCID: PMC3079348. Read the article

    Schwartz M, Glatz AC, Rome JJ, Gillespie MJ. The Amplatzer vascular plug and Amplatzer vascular plug II for vascular occlusion procedures in 50 patients with congenital cardiovascular disease. Catheter Cardiovasc Interv. 2010 Sep 1;76(3):411-7. Cited in PubMed; PMID 20552654. Read the abstract

    Posters and Presentations

    2012

    Gillespie MJ. The role of the congenital interventionalist across the age spectrum [presentation]. Cardiology 2012; 2012 Feb 22-26; Orlando, FL.

    Gillespie MJ. Debate: patients should be offered a Melody valve even if they don't meet indications for surgical pulmonary valve replacement [presentation]. Cardiology 2012; 2012 Feb 22-26; Orlando, FL.

    Gillespie MJ. Management of late arch obstruction [presentation]. Cardiology 2012; 2012 Feb 22-26; Orlando, FL.

    Gillespie MJ. One-stop-shop: EP, intervention and hemodynamics in ACHD patients [presentation]. Cardiology 2012; 2012 Feb 22-26; Orlando, FL.

    Gillespie MJ. Transcatheter PDA closure in the premature infant [presentation]. Cardiology 2012; 2012 Feb 22-26; Orlando, FL.

    Gillespie MJ. Ablation, intervention and hemodynamics: combined EP and interventional procedures [presentation]. Cardiology 2012; 2012 Feb 22-26; Orlando, FL.

    Gillespie MJ. Experimental studies on expanded application of the Melody valve: bilateral branch pulmonary artery Melody valve implantation and mitral valve-in-ring procedure [presentation]. Cardiology 2012; 2012 Feb 22-26; Orlando, FL.

    2011

    Gillespie MJ. Transcatheter pulmonary valve replacement in Tetralogy of Fallot [presentation]. American Society of Echocardiography Annual Meeting, e32011: Essential echocardiography with experts: focus on adult congenital heart disease [presentation]. 2011; New Orleans, LA.

    Gillespie MJ. Melody valve insertion into a tissue valve ring [presentation]. American College of Cardiology Scientific Sessions and i2 Summit; 2011 Apr 3-5; New Orleans, LA.

  • Editorial and Academic Positions

    Editorial positions

    Reviewer

    2011-present, Journal of Clinical and Experimental Medicine
    2010-present, Journal of the American College of Cardiology
    2010-present, American Heart Journal
    2010-present, The American Journal of Cardiology
    2009-present, Circulation: Cardiovascular Interventions
    2008-present, Circulation
    2007-present, Congenital Heart Disease: Clinical Studies from Fetus to Adulthood
    2005-present, Catheterization and Cardiovascular Interventions
    2005-present, Pediatric Cardiology

    Academic committees

    2009-2011, Co-Chairman, Cardiac Center Recruitment and Retention Committee
    2007-2011 Member, Institutional Animal Care and Use Committee
    2007-present, Pediatric Cardiology Fellowship Committee