William J. Greeley, MD, MBA

William J. Greeley, MD, is anesthesiologist-in-chief and chair of the Department of Anesthesiology and Critical Care Medicine at CHOP.

Areas of Expertise: Brain protection strategies during cardiac surgery, Cardiac intensive care medicine, The effects of cardiopulmonary bypass on the brain
Locations: Main Campus
Appointments and Referrals: 1-800-TRY-CHOP (1-800-879-2467)

  • Background

    View my expanded bio.
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  • Education and Training

    Medical School

    MD - University of Texas Medical School, Houston, TX


    Duke University Medical Center, Durham, NC


    Duke University Medical Center, Durham, NC


    Cardiology - Duke University Medical Center, Durham, NC
    Pediatric anesthesia and critical care medicine - The Children's Hospital of Philadelphia, Philadelphia, PA

    Board Certification

    American Board of Anesthesiology
    American Board of Pediatrics
    Diplomate, Federation of US Medical Examiners

  • Titles and Academic Titles


    Chair, Department of Anesthesiology and Critical Care Medicine

    Professor of Anesthesia and Pediatrics, Perelman School of Medicine at the University of Pennsylvania

  • Departments and Services
  • Publications


    Greeley WJ.  Financial Implications in the Care of Complex Congenital Heart Disease.  2001.

    Galli K, Greeley WJ.  Management of children with cardiovascular diseases - anesthetic considerations. In: Principles and practice of pediatric anesthesia, New York: McGraw-Hill; 2000

    Greeley WJ, Kern FH, Schulman SR.  Congenital Heart Disease. In: Estafanous FG, Barash PG, and Reves JG, editors. Cardiac anesthesia:  principles and clinical practice. 2nd ed. Philadelphia: Williams & Wilkins; 2000.

    Greeley WJ, editor. Pediatric anesthesia. New York: Churchill Livingstone, Inc.; 1999.

    Greeley WJ, Steven JM, Nicolson SC, Kern FH. Cardiac (pediatric) anesthesia. In: Miller RD, editor. Anesthesia. New York: Churchill Livingstone, Inc.; 2000.



    Schears G, Creed J, Schultz S, Greeley WJ, Wilson DF, Pastuszko A.  Effect of a patent ductus arteriosis (PDA), flow rate and inspired oxygen on oxygenation of different organs of newborn piglets during normothermic cardiopulmonary bypass.  31st Critical Care Congress, January, 2002 in San Diego, CA


    Pirzadeh A, Mammen A, Kubin J, Reade E, Liu H, Mendoza A, Greeley WJ, Wilson DF, Pastuszko A. Early Regional Response of Apoptotic Activity in Newborn Piglet Brain Following Hypoxia and Ischemia. Neurochem Res. 2010 Sep 26. Read abstract.

    Pirzadeh A, Schears G, Pastuszko P, Liu H, Kubin J, Reade E, Mendoza-Paredes A, Greeley W, Nadkarni V, Wilson DF, Pastuszko A. Effect of deep hypothermic circulatory arrest followed by low-flow cardiopulmonary bypass on brain metabolism in newborn piglets: Comparison of pH-stat and alpha-stat management. Pediatr Crit Care Med. 2010 Jul 1. Read abstract

    Mendoza-Paredes A, Liu H, Schears G, Yu Z, Markowitz SD, Schultz S, Pastuszko P, Greeley WJ, Nadkarni V, Kubin J, Wilson DF, Pastuszko A. Resuscitation with 100%, compared with 21%, oxygen following brief, repeated periods of apnea can protect vulnerable neonatal brain regions from apoptotic injury.  Resuscitation. 2008 Feb;76(2):261-70. Epub 2007 Aug 31. Read abstract.




    Markowitz SD, Mendoza-Paredes A, Liu H, Pastuszko P, Schultz SP, Schears GJ, Greeley WJ, Wilson DF, Pastuszko A. Response of brain oxygenation and metabolism to deep hypothermic circulatory arrest in newborn piglets: comparison of pH-stat and alpha-stat strategies. Ann Thorac Surg. 2007 Jul;84(1):170-6. Read abstract.