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Brian Hanna, MDCM, PhD, FAAP, FACC

Director, Section of Pulmonary Hypertension

Clinical Professor of Pediatrics, Perelman School of Medicine at the University of Pennsylvania



Glatz AC, Geisser D, McCarthy AL, Daniels K, Gillespie M, Hanna B, et al. Prevalence and risk factors for acute occlusive arterial injury following pediatric cardiac catheterization in the modern era at a large volume center [abstract]. ACC.12; 2012 Mar 24-27; Chicago, IL.

Koko E, Meluskey H, Hanna BD. Occurrence of pulmonary hypertension in pediatric heterotaxy syndromes [abstract]. Cardiology 2012 Feb 22-26; 2012; Orlando, FL.


Frank DB, Bshouty Z, Meluskey H, Patterson K, Walker S, Hanna BD. Quantifying vascular loss predicts survival in pediatric pulmonary hypertension: validating a new computational model [abstract]. ATS 2011 International Conference; 2011 May 13-18; Denver, CO.

Dubey S, Meluskey H, Ramsey EZ, Patterson K, Walker S, Hanna. Sildenafil use in pediatric pulmonary hypertension (PH): minimal risk [abstract]. ATS 2011 International Conference; 2011 May 13-18; Denver, CO.

Meluskey HL, Hanna BD, Munson D, Kirpalani H. Mortality estimates for severe BPD complicated by pulmonary hypertension [abstract]. SPR International Meeting, 2011.

Hanna BD, Frank DB, Bshouty Z, Meluskey H. In pre-transplant pulmonary hypertension, does PVR tell the story? [abstract] ISHLT 2011; 2011 Apr 13-16; San Diego, CA.

Hanna, BD, Frank, DB, HL Meluskey, KL Patterson, S Walker, Z. Bshouty. Paradigm shift: quantifying vascular growth in bronchopulmonary dysplasia and pulmonary hypertension [abstract]. SPR 2011.

Rossano J, Hanna BD, et al. Increasing prevalence and decreasing mortality in pulmonary hypertension related hospitalizations in the United States: an analysis of over 20,000 hospital admissions [abstract]. AHA, Fall meeting, 2011.


Mirarchi N, Goldberg DJ, Glatz AC, Marino B, Paisley AM, Paridon S, et al. Sildenafil is well tolerated in children and young adults late after the Fontan operation [abstract]. AHA Fall Meeting, 2010

Healy F, Hanna BD, Hedrick H, Panitch HB. An association between pulmonary hypertension and impaired lung function in infants with congenital diaphragmatic hernia. American Thoracic Society (ATS) International Conference; 2010 May 14-19; New Orleans, LA.

Glatz AC, Akash P, Xiaowei Z, Yoav D, Hanna BD, Gillespie MJ, et al. Radiation exposure from diagnostic and interventional cases in a modern, large-volume pediatric cardiac catheterization laboratory [abstract]. AHA, 11/17/2010.

Lin KY, Sullivan P, Salam A, Kaufman B, Paridon S, Hanna BD, et al. Donor troponin I levels and graft survival in pediatric heart transplantation [abstract]. SPR, 2010.

Niles DE, Hanna BD, Joar E, Diaz LK, Gillespie MJ, Rome JJ, et al. Sternal wall pressure comparable to leaning during cpr impacts intrathoracic pressure and hemodynamics in anesthetized children during cardiac catheterization [abstract]. Journal of Critical Care Medicine, Supplement Dec 2010. 


2010, Department of Pediatrics, Master Clinician Award
2004-11, Faculty Honor Roll: CHOP resident teaching award
2006, Commencement Speaker: Pediatric Resident and Fellow Graduation, CHOP
1992, I.W.K. Staff Recognition Award
1992-95, Dedicated Service Award: Heart and Stroke Foundation, Canada
1991, I.W.K. Resident Teaching Award: Runner-up
1989, Statut de Clinicien-Chercher, FRSQ, Que (#891290)
1987, Claude Giroud Prize: Pediatric Research, McGill
1981-83, Faculty Scholar: Medicine, McGill
1981-83, J.W. McConnell Scholarship: Medicine, McGill




Lin K, Bernadzikowski T, Walker S, Hanna BD, Kaufman B. Heart failure, cardiomyopathy and pulmonary hypertension. In: Gleason M, Rychick J, Shaddy RE, editors. Pediatric practice: cardiology. McGraw-Hill; 2011. p. 251-66.


Ravishankar, C and BD Hanna. Pulmonary Hypertension, In The Requisites-Pediatric Critical Care. Ed: D. Davis and M. Helfaer, Elsevier Publishing Co, 2008.

Tabbut, S, T Domiguez and BD Hanna. Myocarditis, In The Requisites-Pediatric Critical Care. Ed: D. Davis and M. Helfaer, Elsevier Publishing Co, 2008.

Bergelson JM, Hanna BD. Myocarditis and pericarditis. In: Bergelson J, Zaoutis T, Shah SS, editors. Pediatric infectious diseases: the requisites in pediatrics. Philadelphia: Elsevier Publishing Co; 2008.


Hanna BD. Blood flow in the normal and diseased pulmonary artery. In: Fogel M, editor. Ventricular function and blood flow in congenital heart disease. New York: Futura Publishing Co, Inc.; 2005.

Hanna BD. Metabolic abnormalities. In: Shaddy RE, Wernovsky G, editors. Pediatric heart failure. New York: Marcel Decker, Inc.; 2005. 


Paquet M, Hanna BD. Cardiomyopathy. In: Oski FA, Deangelis C, Feigin RD, editors. The principles and practice of pediatrics. 2nd ed. Philadelphia: J.B. Lippincott; 1990. p. 1606-14. 


Paquet M, Hanna BD. Cardiomyopathy.  In: Garson A, Bricker JT, McNammara DG. The science and practice of pediatric cardiology. Philadelphia: Lea and Febiger; 1989.  p. 1617-46. 


Polosa C, Lioy F, Hanna BD. The role of the ventral medulla in the control of sympathetic activity by systemic arterial CO2.  In: Schlaefke ME, Koepchen HP, See WR, editors. Central neurone environment. Berlin (Germany): Springer-Verlag; 1983. p. 214-20.

Editorial and Academic Positions

Editorial positions


2008-present, Pediatric Critical Care Medicine
2008-present, Pediatrics
2008-Present, Journal of Pediatrics
2007-present, Congenital Heart Disease
2006-present, Pediatric Transplantation
2006-present, Cardiology
2001-present, Pediatric Emergency Care
2001-present, The Annals of Thoracic Surgery
1996-present, Journal of Critical Care Medicine
1995-present, Journal of Heart and Lung Transplantation

Academic and institutional committees

Department committees

The Children’s Hospital of Philadelphia, Cardiac Center

  • 2003-present Director, Section of Pulmonary Hypertension
Hospital committees

The Children's Hospital of Philadelphia

  • 2001-present, Central Line Committee


Memberships in professional organizations

International societies

Pulmonary Hypertension Association

  • 2012-present, Insurance Advocacy Committee
  • 2009-present, Medically-led Sessions Committee
National societies

American College of Cardiology, Fellow

  • 2010-11, Cardioserve Research Panel

American Academy of Pediatrics, Fellow

American Heart Association

  • 2011-present, CCD Committee
  • 2011-present, AHA-ATS writing committee for Pediatric PH Guidelines

American Thoracic Society

  • 2011-present, AHA-ATS writing committee for Pediatric PH Guidelines

Royal College of Physicians and Surgeons of Canada, Fellow

Original Papers


Goldberg DJ, French B, Szwast AL, McBride MG, Marino BS, Mirarchi N, et al. Impact of sildenafil on echocardiographic indices of myocardial performance after the Fontan operation. Pediatr Cardiol. 2012 Jun;33(5):689-96. Epub 2012 Feb 14. Cited in Pubmed; PMID 22331056. Read the abstract


Mallory GB Jr, Hanna BD, Ivy DD, Shardonofsky F, Farber HJ. Management and controversies in pediatric pulmonary hypertension. Pediatr Allergy Immunol Pulmonol. 2011 Mar 4;22(4):139-150. Cited in PubMed; PMCID: PMC3136886. Read the article

Goldberg DJ, Quartermain MD, Glatz AC, Hall EK, Davis E, Kren SA, et al. Doppler tissue imaging in children following cardiac transplantation: a comparison to catheter derived hemodynamics. Pediatr Transplant. 2011 Aug;15(5):488-94. doi: 10.1111/j.1399-3046.2011.01503.x. Epub 2011 Apr 25. Cited in PubMed; PMCID: PMC3140578. Read the article

Lin KY, Sullivan P, Salam A, Kaufman B, Paridon S, Hanna BD, et al. Troponin I levels from donors accepted for pediatric heart transplantation do not predict recipient graft survival. J Heart Lung Transplant. 2011 Aug;30(8):920-7. Epub 2011 Apr 13. Cited in PUbMed; PMCID: PMC3129377.  Read the article 

Goldberg DJ, French B, McBride MG, Marino BS, Mirarchi N, Hanna BD, et al. Impact of oral sildenafil on exercise performance in children and young adults after the Fontan operation: a randomized, double-blind, placebo-controlled, crossover trial. Cited in PubMed; PMID 21382896. Read the article


Glatz AC, Zhu X, Gillespie MJ, Hanna BD, Rome JJ. Use of angiographic CT imaging in the cardiac catheterization laboratory for congenital heart disease. JACC Cardiovasc Imaging. 2010 Nov;3(11):1149-57. Cited in PubMed; PMID 21071003. Read the abstract

O'Connor MJ, Rider NL, Thomas Collins R, Hanna BD, Holmes Morton D, Strauss KA. Contemporary management of congenital malformations of the heart in infants with Ellis - van Creveld syndrome: a report of nine cases. Cardiol Young. 2011 Apr;21(2):145-52. Epub 2010 Nov 12. Cited in PubMed; PMID 21070693. Read the abstract

 O'Connor MJ, Menteer J, Chrisant MR, Monos D, Lind C, Levine S, et al. Ventricular assist device-associated anti-human leukocyte antigen antibody sensitization in pediatric patients bridged to heart transplantation. J Heart Lung Transplant. 2010 Jan;29(1):109-16. Cited in PubMed; PMID 20123248. Read the abstract

Posters and Presentations


Hanna BD. Use of PAH directed therapies in patients with single ventricles [presentation]. ISHLT 2012: 32nd Annual Meeting and Scientific Sessions of International Society for Heart & Lung Transplantation; 2012 Apr 18; Prague, Czech Republic.


Hanna BD. Bronchopulmonary Dysplasia and CDH [presentation]. 60th Annual ACC Scientific Sessions; 2011 Apr 5; New Orleans, LA.

Hanna BD. The who, what, why and when of PH in Pediatric CLD [presentation]. Pittsburgh Children’s Hospital, PICU and NICU Rounds; 2011 Apr 28; Pittsburgh, PA.

Hanna BD. PH in pediatric CLD [presentation]. Pittsburgh Children’s Hospital, Pulmonary Rounds; 2011 Apr 29; Pittsburgh, PA.

Hanna BD. The fun of cathing pediatric PH [presentation]. Pittsburgh Children’s Hospital, Cardiology Rounds; 2011 Apr 29; Pittsburgh, PA.

Hanna BD. Pulmonary hypertension in sickle cell disease [presentation]. ATS 2011; 2011 May 15; Denver, CO.

Hanna BD. Plenary session: Pulmonary hypertension in sickle cell disease [presentation]. Sickle Cell Disease Association of America: Philadelphia/Delaware Valley Chapter; 2011 Sep 17; Philadelphia, PA.

Hanna BD. Off-label use of medications in PH [panel presentation]. 2011 PH Resource Network Symposium; 2011 Sep 24; Arlington, VA.

Hanna BD. The crossroads of congenital heart defects and PH [presentation]. 2011 Sep 24; Arlington, VA.

Hanna BD. Moving toward improved prognosis for pediatric PH [presentation]. The 9th Annual Macdonald Dick Lecture, Pediatric Grand Rounds, University of Michigan; 2011 Oct 11; Ann Arbor, MI.


Hanna BD. Pediatric pulmonary hypertension: the angst and the hope [presentation]. Divisional Conference, John Hopkins Division of Pulmonary Medicine; 2010 Jan 26; Baltimore, MD.

Hanna BD. The changing face of pediatric pulmonary hypertension [presentation]. St Joseph’s Hospital: Eller Congenital Heart Center Grand Rounds; 2010 Feb 5; Phoenix, AZ.

Hanna BD. Pulmonary vascular capacity, a unifying concept for pediatric pulmonary hypertension [presentation]. Hackensack Medical Center Neonatal Rounds; 2010 Feb 10; Hackensack, NJ>

Hanna BD. Neonatal and childhood lung transplantation, where are we? [presentation]. 3rd International Neonatal and childhood pulmonary vascular disease conference; 2010 Mar 11; Banff, Canada.

Hanna BD. Neonatal and childhood pulmonary hypertension [presentation]. I.W.K. Women’s and Children’s Hospital; 2010 Oct 29; Halifax, Nova Scotia, Canada.

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