Mary C. Harris, MD

Mary Catherine Harris, MD, is an attending neonatologist with the Division of Neonatology at The Children's Hospital of Philadelphia.

Areas of Expertise: Immunology, Medical education, Neonatal ID
Locations: Main Campus
Appointments and Referrals: 1-800-TRY-CHOP (1-800-879-2467)

  • Background

    Mary Catherine Harris, MD, is a senior attending neonatologist at The Children's Hospital of Philadelphia and the Hospital of the University of Pennsylvania, an Advisory Dean at the Perelman School of Medicine at the University of Pennsylvania and director of residency recruitment at Children's Hospital. She also is a Professor of Pediatrics at the Perelman School of Medicine at the University of Pennsylvania.

    After receiving her medical degree from Dartmouth College in Hanover, NH, Dr. Harris completed a residency in Pediatrics at the Children's Hospital Medical Center (Harvard), Boston, Massachusetts and a fellowship in neonatal-perinatal medicine at the University of Pennsylvania School of Medicine. Currently, Dr. Harris serves as attending physician in the Newborn/Infant Intensive Care Unit at The Children's Hospital of Philadelphia. She is also highly active in recruitment, training and mentoring of medical students, residents and fellows in Pediatrics and Neonatology. She is a member of the Graduate Education Committee and a faculty advisor for medical students, residents and fellows.

    Dr. Harris' areas of expertise include infectious diseases and the inflammatory response, an interest that has been cultivated over many years. Her research has focused on the role of cytokines in sepsis and necrotizing enterocolitis in newborn infants. Dr. Harris has published extensively on neonatal septicemia, meningitis and NEC. Her secondary research interest is in the area of medical education, where she has published on issues such as career choices among pediatric residents, and the value of the interview in the residency application process.

  • Education and Training

    Medical School

    MD - Dartmouth Medical School, Hanover, NH


    Children's Hospital Medical Center, Harvard University, Boston, MA


    University of Pennsylvania School of Medicine, Philadelphia, PA

    Board Certification

    Neonatal-Perinatal Medicine

  • Titles and Academic Titles

    Attending Neonatologist

    Professor of Pediatrics, Perelman School of Medicine at the University of Pennsylvania

  • Departments and Services
  • Research Interests
  • Publications




    Kilpatrick L, Harris MC. Cytokines and inflammatory response in the fetus and neonate. In: Polin RA, Fox WW, Abman SH editors. Fetal and neonatal physiology. 4th ed. Philadelphia: Saunders; 2010.



    Padula, MA; Dewan, ML; Shah, SS; Padula, AM; Srinivasan, L; McGowan, KL; Mahoney, KR; Harris, MC. Risk Factors Associated with Laboratory-confirmed Bloodstream Infections in a Tertiary Neonatal Intensive Care Unit. Pediatr Infect Dis J. 2014 Oct. 33 (10):1027-1032. Read the abstract.


    A novel urine peptide biomarker-based algorithm for the prognosis of necrotising enterocolitis in human infants.
    Sylvester KG, Ling XB, Liu GY, Kastenberg ZJ, Ji J, Hu Z, Peng S, Lau K, Abdullah F, Brandt ML, Ehrenkranz RA, Harris MC, Lee TC, Simpson J, Bowers C, Moss RL. Gut. 2013 Sep 18. doi: 10.1136/gutjnl-2013-305130. [Epub ahead of print]

    Clinical features of three girls with mosaic genome-wide paternal uniparental isodisomy.
    Kalish JM1, Conlin LK, Bhatti TR, Dubbs HA, Harris MC, Izumi K, Mostoufi-Moab S, Mulchandani S, Saitta S, States LJ, Swarr DT, Wilkens AB, Zackai EH, Zelley K, Bartolomei MS, Nichols KE, Palladino AA, Spinner NB, Deardorff MA. Am J Med Genet A. 2013 Aug;161A(8):1929-39. doi: 10.1002/ajmg.a.36045. Epub 2013 Jun 26.

    Species-specific PCR improves detection of bacterial pathogens in parapneumonic empyema compared with 16S PCR and culture.
    Blaschke AJ, Byington CL, Ampofo K, Pavia AT, Heyrend C, Rankin SC, McGowan KL, Harris MC, Shah SS. Pediatr Infect Dis J. 2013 Mar;32(3):302-3. doi: 10.1097/INF.0b013e3182784ec1


    New technologies for the rapid diagnosis of neonatal sepsis.
    Srinivasan L, Harris MC. Curr Opin Pediatr. 2012 Apr;24(2):165-71. doi: 10.1097/MOP.0b013e3283504df3. Review. PMID: 22273634.

    Lumbar puncture in the neonate: challenges in decision making and interpretation.
    Srinivasan L, Harris MC, Shah SS. Semin Perinatol. 2012 Dec;36(6):445-53. doi: 10.1053/j.semperi.2012.06.007. Review. PMID: 23177804

    Can broad-range 16S ribosomal ribonucleic acid gene polymerase chain reactions improve the diagnosis of bacterial meningitis? A systematic review and meta-analysis.
    Srinivasan L, Pisapia JM, Shah SS, Halpern CH, Harris MC. Ann Emerg Med. 2012 Nov;60(5):609-620.e2. doi: 10.1016/j.annemergmed.2012.05.040. Epub 2012 Aug 9. Review. PMID: 22883680

    Cerebrospinal fluid reference ranges in term and preterm infants in the neonatal intensive care unit.
    Srinivasan L, Shah SS, Padula MA, Abbasi S, McGowan KL, Harris MC. J Pediatr. 2012 Oct;161(4):729-34. doi: 10.1016/j.jpeds.2012.03.051. Epub 2012 May 9. PMID: 22575245