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Haralambos Ischiropoulos, PhD

Research Professor of Pediatrics and Pharmacology, Perelman School of Medicine at the University of Pennsylvania


2007, Gisela and Dennis Alter Chair in Pediatric Neonatology
1998, Bodossaki Foundation Academic Prize in Medicine
1997-present, Joseph Stokes Jr. Investigator, Children's Hospital of Philadelphia
1996-2001, Established Investigator, American Heart Association
1995, Young Investigator Award, Oxygen Society
1994, Young Investigator Award, International Society for Free Radical Research
1993-1996, Parker B. Francis Fellowship in Pulmonary Research
1988, Dr. Frederic Valergakis Graduate Grant
1984, Dreyfus Prize in Chemistry, American Institute of Chemists Student Award

Editorial and Academic Positions

Editorial positions

2009-2013, Editorial board, Journal of Biological Chemistry
2009-present, Associate editor, Free Radical Biology and Medicine
2005-2009, Editorial Advisory Panel, Biochemical Journal
2005-2009, Current Respiratory Medicine Reviews
2003-present, Faculty Chemical Biology Section, Faculty 1000

Academic committees

2009-2013, Research Institute Faculty Advisory Committee on Compliance, The Children's Hospital of Philadelphia
2007-present, Deputy Chair, Research Institute-Cores Committee, The Children's Hospital of Philadelphia
2006-present, Director of Neonatology Research, The Children's Hospital of Philadelphia Research Institute


Memberships in professional organizations

American Association for the Advancement of Science
American Pediatric Society
American Physiological Society
American Society for Biochemistry and Molecular Biology
Gordon Research Conferences

  • Chair, Nitric Oxide Conference, 2015
  • Co-chair, Oxygen Radicals Conference, 2004

Nitric Oxide Society
Society for Free Radical Biology and Medicine

  • President, 2010-2012
  • President-Elect, 2009-2010
  • Secretary General, 2005-2009

Society for Neuroscience
Society for Pediatric Research

NIH review panels

2012-present, NINDSINST-2 panel for F31 and K99/R00 applications

2011-present, National Center for Research Resources COBRE phase I and Phase III review panels

2007-present, Special Emphasis Panels and ad hoc NOMD study section

2005, NIH Center for Scientific Review; Molecular, Developmental and Cellular Neuroscience Working Group for Study Section Design

2004, National Institute on Aging; RFA on Proteomics and Aging review panel

2003-2004, National Institute of Neurological Disorders and Stroke, Udall Centers for Parkinson's disease Research

2001, National Institute of Environmental Health Science: special emphasis panel for antioxidants and nutrition

1999, 2002, National Heart, Lung and Blood Institute, Program Projects Review Panels

1998-2003, Cell Death and Injury in Neurodegeneration-formerly Brain Disorders and Clinical Neuroscience-3

Original Papers


Doulias P-T. Tenopoulou M, Greene, JL, Raju, K and Ischiropoulos H. Nitric oxide regulates mitochondrial fatty acid metabolism through reversible protein S-nitrosylation. Sci. Signal. 6:rs1-7,2013.


Martinez M, Cuker A, Mills A, Lightfoot R, Fan Y, Tang "VB, Hazen SL, Ischiropoulos H. Nitrated fibrinogen is a biomarker of oxidative stress in venous thromboembolism. Free Radic Bioi Med. 53:230-236,2012. PMC3392413.

Malleus K and Ischiropoulos H, Regional deficiencies in chaperone-mediated autophagy underlie a-synuclein aggregation and neurodegeneration. Neurobiol. Dis. 46:732-744,2012. PMC335297. 

Thomson L, Tenopoulou M, Lightfoot R, Tsika E, Parastatidis I, Martinez M, Greco TM; Doulias P-T, Wu Y, Tang WHW, Hazen SL, Ischiropoulos H. Immunoglobulins against tyrosine nitrated epitopes in coronary artery disease. Circulation 126:2392-2401, 2012. PMC3501999.

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