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Robert G. Kalb, MD

Neurology Researcher

Professor of Neurology, Perelman School of Medicine at the University of Pennsylvania


2002,  Decade of Service Award - Teaching and Guidance, Yale University
2001, NASA Group Achievement Award - Neurolab Spacelab Mission Science Team
2000,  Attending of the Year for Teaching Dedication, Yale University
1997,  Attending of the Year for Teaching Dedication, Yale University
1992,  Attending of the Year for Teaching Dedication, Yale University
1987,  Clinical Investigator Development Award
1982, Upjohn Achievement Award for Academic Excellence
1980,  David Barr Research Fellowship

Editorial and Academic Positions

Editorial positions

2009-present,  Associate Editor, Journal of Neuroscience
2008-present,  Associate Editor, Frontiers in Molecular Neuroscience
2004-present,  Associate Editor, Neuroscience Letters

Ad hoc reviewer

Journal of Neuroscience
Journal of Physiology
Proceedings of the National Academy of Science, USA
European Journal of Neuroscience
Journal of Neurophysiology
Journal of Neurobiology
Brain Research
Journal of Neurocytology
Neuroscience Letters
Journal of Neurochemistry
Experimental Brain Research
Experimental Neurology

Academic and institutional committees

2010-present,  Evaluator, MD, PhD Admissions Committee
2010-present,  Reviewer, Pediatric Cardiology Scholarship Oversight Committee
2009-present, Chair, IACUC at CHOP
2007-present,  Member, Institutional Intellectual Property Advisory Committee, CHOP


Memberships in professional organizations

International organizations

2009-present,  Agenzia Di Ricerca Per La Sclerosi Laterale Amiotrofica (Grant proposal reviewer)
2005-present,  Association Francaise Contre Les Myopathies (Grant proposal reviewer)
1987-present, Society for Neuroscience
1985-present, American Association for the Advancement of Science

National organizations

2009-2011, "Cellular and Molecular Biology of Neurodegeneration" NIH Study Section (Chairman)
1998-present, National Institutes of Health Neuroscience Study Section (MDCN2)
1997-present, American Neurologic Association
1995-present, American Academy of Neurology
1989-present, NIH,NINDS, NLS-3 study section (Grant proposal reviewer)
1987-present, NIH, NINDS (Technical evaluation group for contract proposals)

Original Papers


Boccitto M, Lamitina T, Kalb RG. Daf-2 signaling modifies mutant SOD1 toxicity in C. elegans. PLoS One. 2012;7(3):e33494. Epub 2012 Mar 20. Cited in PubMed; PMID 22457769. Read the article

Couthouis J, Hart MP, Erion R, King OD, Diaz Z, Nakaya T, et al. Evaluating the role of the FUS/TLS-related gene EWSR1 in amyotrophic lateral sclerosis. Hum Mol Genet. Epub 2012 Apr 6. Cited in PubMed; PMID 22454397. Read the abstract


Couthouis J, Hart MP, Shorter J, DeJesus-Hernandez M, Erion R, Oristano R, et al. A yeast functional screen predicts new candidate ALS disease genes. Proc Natl Acad Sci U S A. 2011 Dec 27;108(52):20881-90. Epub 2011 Nov 7. Cited in PubMed; PMID 2206782. Read the article

Zhai J, Zhou W, Li J, Hayworth CR, Zhang L, Misawa H, et al. The in vivo contribution of motor neuron TrkB receptors to mutant SOD1 motor neuron disease. Hum Mol Genet. 2011 Nov 1;20(21):4116-31. Epub 2011 Aug 4. Cited in PubMed; PMID 21816949.Hum Mol Genet. 2011 Nov 1;20(21):4116-31. Epub 2011 Aug 4. Read the abstract

Yu Z, Zhu Y, Chen-Plotkin AS, Clay-Falcone D, McCluskey L, Elman L, et al. PolyQ repeat expansions in ATXN2 associated with ALS are CAA interrupted repeats. PLoS One. 2011 Mar 29;6(3):e17951. Cited in PubMed; PMID 21479228. Read the article

Jeong GB, Mojsilovic-Petrovic J, Boccitto M, Kalb R. Signaling events in axons and/or dendrites render motor neurons vulnerable to mutant superoxide dismutase toxicity. J Neurosci. 2011 Jan 5;31(1):295-9. Cited in PubMed; PMIC 21209215. Read the abstract

Posters and Presentations


Kalb RG. The role of growth factor signaling and aging pathways in neurodegenerative diseases [presentation]. Johns Hopkins University; 2011 Feb; Baltimore, MD.


Kalb RG. From molecular machines to locomotor behavior [presentation]. Case Western Reserve University Department of Neurosciences; 2010 Oct; Cleveland, OH.

Kalb RG. A few heresies along the road to effective therapy for motor neuron disease [presentation].  Neuroscience Center, Massachusetts General Hospital, Harvard Medical School; 2010 Jun; Boston, MA.

Kalb RG. Aging pathways and neurodegenerative disease [presentation].  Department of Neurology Grand Rounds, University of Wisconsin; 2010 Jan;  Madison, WI.


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