Michele Lambert, MD

Michele  Lambert, MD, is a Pathologist with the Division of Hematology at The Children's Hospital of Philadelphia.

Locations: Main Campus
Appointments and Referrals: 1-800-TRY-CHOP

  • Education and Training

    Medical School

    MD - University of Medicine and Dentistry of New Jersey, Newark, NJ

    Internship

    Pediatrics - St. Christopher's Hospital for Children, Philadelphia, PA

    Residency

    Pediatrics (Chief Resident) - St. Christopher's Hospital for Children, Philadelphia, PA

    Fellowship

    Pediatric Hematology/Oncology - The Children's Hospital of Philadelphia, Philadelphia, PA

    Board Certification

    American Board of Pediatrics
    American Board of Pediatrics/Hematology-Oncology

    Undergraduate Degree

    BS in Biology - Rensselaer Polytechnic Institute, Troy, NY

    Graduate Degree

    MTR - University of Pennsylvania, Philadelphia, PA

  • Titles and Academic Titles

    Attending Physician

    Assistant Professor of Pediatrics, Perelman School of Medicine at the University of Pennsylvania

  • Centers and Programs
  • Publications

    Books

    Chapters

    2013

    Lambert, MP, Poncz, M: Inherited Thrombocytopenias. Platelets. Michelson, AD (eds.). Elsevier Science, 2nd edition; 3rd edition: 985-998, 2007, 2013.

    2012

    Lambert, M: Autoimmune Hemolytic Anemia. The 5-Minute Pediatric Consult. Schwartz, MW, Bell, LM, Bingham, PM, Chung, EK, Friedman, DF, Tanel, RE, Mamula, P, Loomes, KM and Mascarenhas, M (eds.). Lippincott, Williams & Wilkins, 5th edition, 2008, 2012.

    Lambert, M: Glucose-6 Phosphate Dehydrogenase Deficiency. The 5-Minute Pediatric Consult. Schwartz, MW, Bell, LM, Bingham, PM, Chung, EK, Friedman, DF, Tanel, RE, Mamula, P, Loomes, KM and Mascarenhas, M (eds.). Lippincott, Williams & Wilkins, 5th edition, 2008, 2012.

    Lambert, MP: Anemia of Chronic Disease. The 5-Minute Pediatric Consult. Schwartz, MW, Bell, LM, Bingham, PM, Chung, EK, Friedman, DF, Tanel, RE, Mamula, P, Loomes, KM and Mascarenhas, M (eds.). Lippincott, Williams & Wilkins, 5th edition, 2008, 2012.

    Lambert, MP: Hereditary Spherocytosis. The 5-Minute Pediatric Consult. Schwartz, MW, Bell, LM, Bingham, PM, Chung, EK, Friedman, DF, Tanel, RE, Mamula, P, Loomes, KM and Mascarenhas, M (eds.). Lippincott, Williams & Wilkins, 5th edition, 2008, 2012.

    Abstracts

    2014

    Ben J. Samelson-Jones, Michele P. Lambert: Use of Recombinant Factor VIIa (rVIIa) in Glanzmann's Thrombasthenia: A Systematic Review of the Literature. American Society of Hematology/Oncology Annual Meeting, Chicago, IL April 2014.

    2013

    Ingmar Bruns, MD, Daniel Lucas, PhD, Sandra Pinho, PhD, Jalal Ahmed, Michele P Lambert, MD, Christoph Scheiermann, PhD, Yuya Kunisaki, MD, PhD, Mortimer Poncz, MD and Paul S. Frenette, MD: Megakaryocytes Regulate Hematopoietic Stem Cell Quiescence Via PF4 Secretion. American Society of Hematology Plenary Session December 2013.

    David T. Teachey, MD, TIffaney Vincent, Kim Smith-Whitley, MD, Michele P Lambert, MD, Alix E. Seif, MD, MPH, James T. Casper, MD and Stephan A Grupp, MD, PhD: Targeting mTOR Signaling Leads To Complete and Durable Responses In Children With Multi-Lineage Autoimmune Cytopenias, Including ALPS, SLE, Evans and CVID. American Society of Hematology, Oral Presentation December 2013.

    Corinna L. Schultz, MD and Michele P Lambert, MD: Influence Of Updated ASH Guidelines On Practice Patterns In Management Of Newly Diagnosed Childhood ITP, 2007-2012. American Society of Hematology, Oral Presentation December 2013.

    Cassie N. Kline, MD; Richard Hodinka, MD; Michele P. Lambert, MD: Investigating correlation between common upper respiratory and gastrointestinal viral infections and Idiopathic Thrombocytopenic Purpura. American Society of Pediatric Hematology/Oncology annual meeting; Poster presentation Apr 2013.

    2012

    Michele P. Lambert, Donna McDonald-McGinn, Elaine Zakai: Hematologic Manifestations of 22qDS. 22qDeletion Syndrome meeting, Lake Buena Vista, FL July 2012.

    Xiao L, Poncz M, Lambert MP: Platelet Factor 4 (PF4) causes cell cycle arrest in megakaryocytes by inactivating CDC2 (CDK1) and CDK2 Gordon Research Conference on Hemostasis March 2012.

    Lambert MP, Xiao L, Meng R, Marks M, Poncz M: Alpha-granule protein recycling during megakaryopoiesis: Platelet factor 4 (PF4) is taken up by megakaryocytes (Megs) through a lipoprotein receptor related protein-1 (LRP1) dependent process and is available for release by stimulated Megs Platelets 2012; 7th International Platelet Symposium March 2012.

    Papers

    2014

    Sullivan SK, Mills JA, Koukouritaki SB, Vo KK, Lyde RB, Paluru P, Zhao G, Zhai L, Sullivan LM, Wang Y, Kishore S, Gharaibeh EZ, Lambert MP, Wilcox DA, French DL, Poncz M, Gadue P.: High-level transgene expression in induced pluripotent stem cell-derived megakaryocytes: correction of Glanzmann thrombasthenia. Blood. 123(5): 753-7, Jan 2014. PMCID: PMC3907760

    2013

    Lambert Michele P, Sullivan Spencer K, Fuentes Rudy, French Deborah L, Poncz Mortimer: Challenges and promises for the development of donor-independent platelet transfusions. Blood 121(17): 3319-24, Jan 2013. PMCID: PMC3976218

    Teachey DT, Lambert MP.: Diagnosis and management of autoimmune cytopenias in childhood. Pediatr Clin North Am. 60(6): 1489-511, December 2013.

    2012

    Lambert Michele P, Jiang Jing, Batra Vandana, Wu Chao, Tong Wei: A novel mutation in MPL (Y252H) results in increased thrombopoietin sensitivity in essential thrombocythemia. American journal of hematology 87(5): 532-4, May 2012. PMCID: PMC3388505

    Lambert Michele P, Reznikov Alisa, Grubbs Allison, Nguyen Yvonne, Xiao Liqing, Aplenc Richard, Raouva Lubica, Poncz Mortimer: Platelet Factor 4 Platelet Levels Are Inversely Correlated with Steady-State Platelet Counts and with Platelet Transfusion Needs in Pediatric Leukemia Patients. Journal of thrombosis and haemostasis : JTH 10(7): 1442-6, May 2012. PMCID: PMC3389572

  • Awards and Honors

    2011, International Society on Thrombosis and Haemostasis New Investigator Travel Award
    2009, International Society of Thrombosis and Haemostasis Young Investigator Travel Award
    2006, American Society of Pediatric Hematology/Oncology Young Investigator Travel Award
    2005, American Society of Hematology Young Investigator Travel Award
    1998, UMDNJ-NJMS Alumni Association Award in honor of Dr. Franklin Behrle
    1997, UMDNJ-NJMS Alumni Association Scholarship
    1985-1998, UMDNJ-NJMS Joseph Muscarelli Memorial Scholarship
    1995, Alpha Epsilon Delta - Premedical honor society

  • Editorial and Academic Positions

    Editorial positions

    2009-present, Pediatric Blood and Cancer, Ad Hoc Reviewer
    2009-preswent, Blood, Ad Hoc Reviewer

    Academic and institutional committees

    2008-2012, Member IRB-C, The Children's Hospital of Philadelphia

  • Leaderships

    Memberships in professional organizations

    2007-present, International Society of Thrombosis and Haemostasis
    2014, NIH/NHLBI (Grant Reviewer; Microfluidic Assays SBIR/STTR)
    2011-present, Society for Pediatric Research/Pediatric Academic Society
    2008-present, Platelet Disorder Support Association
    2008-present, Cornelia De Lange Foundation, Member Medical Advisory Board
    2007-present, American Society of Pediatric Hematology/Oncology
    2007-present, American Society of Hematology
    1999-present, American Medical Association