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Mary B. Leonard, MD, MSCE

Director of Research, Division of Nephrology

Professor of Pediatrics and Epidemiology, Perelman School of Medicine at the University of Pennsylvania

Specialties and Services

Practice Locations


MD - Stanford University School of Medicine, Stanford, CA

MS in Clinical Epidemiology - University of Pennsylvania Philadelphia, PA


Pediatrics - The Children’s Hospital of Philadelphia, Philadelphia, PA


Pediatric Nephrology - The Children’s Hospital of Philadelphia, Philadelphia, PA

Board Certification


Year Appointed


Special Interests

Osteoporosis in children
Effects of glucocorticoid therapy and inflammation on body composition and bone development in children with chronic diseases
Imaging techniques to assess the impact of kidney disease on skeletal microarchitecture and strength
Effects of vitamin D deficiency on cardiovascular disease and physical function in adults with CKD
Anabolic bone therapy in chronic disease

Research Interests

Patient oriented research in vitamin D and physical functioning in CKD
Bone health in pediatric Crohn disease:a low magnitude mechanical stimulus trial
Changes in skeletal microarchitecture following renal transplantation
Vitamin D deficiency, physical performance and cardiovascular outcomes in CRIC
Bone health of obese adolescents during weight loss
Osteoporosis treatment response assessed by micromechanical modeling of MRI data
Bone water and mineralization measured by nuclear magnetic resonance
Effect of chronic proton pump Inhibitor therapy on bone mineral density and bone strength
Quantifying bone mineral phosphorus in patients with osteomalacia by solid state 31 P MRI 

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