Areas of Expertise:
Research concerning site-specific therapy for cardiovascular disease focusing on valve replacement surgery, Cardiac arrhythmias and post-angioplasty surgery
Locations: Main Campus
Appointments and Referrals: 1-800-TRY-CHOP
- Education and Training
Johns Hopkins University School of Medicine, Baltimore, Md.
Johns Hopkins Hospital, Baltimore, Md.
Children's Hospital, Boston, Mass.
American Board of Pediatrics
- Titles and Academic Titles
William J. Rashkind Endowed Chair in Pediatric Cardiology
Professor of Pediatrics, Perelman School of Medicine at the University of Pennsylvania
- Centers and Programs
Chorny M, Fishbein I, Yellen BB, Alferiev IS, Bakay M, Ganta S, Adamo R, Amiji M, Friedman G, Levy RJ. Targeting stents with local delivery of paclitaxel-loaded magnetic nanoparticles using uniform fields. Proc Natl Acad Sci U S A. 2010 May 4;107(18):8346-51. Epub 2010 Apr 19. Read abstract
Chorny M, Hood E, Levy RJ, Muzykantov VR. Endothelial delivery of antioxidant enzymes loaded into non-polymeric magnetic nanoparticles. J Control Release. 2010 May 18. [Epub ahead of print]. Read abstract
Ueda M, Alferiev IS, Simons SB, Hebbel RP, Levy RJ, Stachelek SJ. CD47-dependent molecular mechanisms of blood outgrowth endothelial cell attachment on cholesterol-modified polyurethane. Biomaterials. 2010 Sep;31(25):6394-9. Epub 2010 Jun 9. Read abstractPolyak B, Fishbein I, Chorny M, Alferiev I, Williams D, Yellen B, Friedman G, Levy RJ: High field gradient targeting of magnetic nanoparticle-loaded endothelial cells to the surfaces of steel stents. Proc Natl Acad Sci U S A 2008, 105:698-703.Chorny M, Fishbein I, Alferiev IS, Nyanguile O, Gaster R, Levy RJ: Adenoviral gene vector tethering to nanoparticle surfaces results in receptor-independent cell entry and increased transgene expression. Mol Ther 2006, 14:382-391.
Fishbein I, Alferiev IS, Nyanguile O, Gaster R, Vohs JM, Wong GS, Felderman H, Chen IW, Choi H, Wilensky RL, Levy RJ: Bisphosphonate-mediated gene vector delivery from the metal surfaces of stents. Proc Natl Acad Sci U S A 2006, 103:159-164.