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Kathleen M. Loomes, MD

Attending Physician

Associate Professor of Pediatrics, Perelman School of Medicine at the University of Pennsylvania

Abstracts

2011

Kamath BM, Hutchinson A, Bauer R, Gerfen J, Krantz ID, Piccoli DA, et al. NOTCH2 mutations in Alagille syndrome [abstract oral presentation]. International Liver Congress; 2011 Mar 31; Berlin, Germany.

Awards

2003, Researcher of the Year, American Liver Foundation Delaware Valley Chapter

1999, 3rd Prize, 37th Annual Komarov Prize Competition, Philadelphia Gastrointestinal Research Forum

1997, Fellows Teacher of the Year Award, CHOP

1992, Alpha Omega Alpha, University of Texas Southwestern Medical School

1988, Phi Beta Kappa, Rice University

Books

Books

2009

Zorc JJ, Alpern ER, Brown LW, Loomes KM, Marino BS, Mollen CJ, et al., editors. Clinical handbook of pediatrics. Philadelphia: Lippincott Wiliams & Wilkins; 2009.

2008

Schwartz MW, Bell LM, Bingham PM, Chunk EK, Friedman DF, Loomes KM, et al., editors. The 5-minute pediatric consult. Philadelphia: Lippincott Williams & Wilkins; 2008.

Chapters

2011

Emerick KM, Loomes KM. Pediatric cholestatic liver disease with genetic etiology. In: Wylie R, Hyams JS, Kay M, editors. Pediatric gastrointestinal and liver disease. 4th ed. Philadelphia: Elsevier Mosby Saunders; 2011.

2010

Kamath BM, Loomes KM, Piccoli DA. JAGGED1/NOTCH2 sequence in Alagille syndrome. In: Murray K, Larson AM, editors. Fibrocystic diseases of the liver. New York: Springer-Verlag; 2010.

2008

Ryan MJ, Loomes KM. Congenital hepatic fibrosis. In: Liacouras CA, Piccoli DA, editors. Pediatric gastroenterology: the requisites. Philadelphia: Mosby Elsevier; 2008. p. 253-60.

Franciosi J, Loomes KM. Wilson disease. In: Liacouras CA, Piccoli DA, editors. Pediatric gastroenterology: the requisites. Philadelphia: Mosby Elsevier; 2008. p. 298-304.

Loomes KM. Biliary Atresia. In: Schwartz MW, Bell LM, Bingham PM, Chunk EK, Friedman DF, Loomes KM, et al., editors. The 5-minute pediatric consult. Philadelphia: Lippincott, Williams and Wilkins; 2008. p 104-5.

Loomes KM. Biliary Jaundice. In: Schwartz MW, Bell LM, Bingham PM, Chunk EK, Friedman DF, Loomes KM, et al., editors. The 5-minute pediatric consult. Philadelphia: Lippincott, Williams and Wilkins; 2008. p. 472-3.

2004

Russo P, Loomes KM. Diseases of the intrahepatic biliary tree: paucity of the intrahepatic bile ducts. In: Russo L, Rucchelli E, Piccoli DA, editors. Pathology of pediatric gastrointestinal and liver disease. 2004. p. 220-36.

2002

Loomes KM, Kusumi K, Spinner NB. Notch genes. In: Wiley Encyclopedia of Molecular Medicine. 2002. p. 2287-90.

Editorial and Academic Positions

Editorial positions

2009-present, Ad Hoc reviewer, PLOS Genetics

2008-2009, Co-editor, Cases in Pediatric Gastroenterology from The Children's Hospital of Philadelphia, The Medscape Journal of Medicine

2008-present, Ad Hoc reviewer, Journal of Pediatrics

2007-present, Associate Editor, Pediatric Gastroenterology, Clinical Handbook of Pediatrics

2006-present, Associate Editor, Pediatric Gastroenterology, 5-minute Pediatric Consult Textbook

2006-present, Ad Hoc Reviewer, Gastroenterology

2004-present, Ad Hoc Reviewer, Journal of Pathology

2003-present, Ad Hoc Reviewer, Human Molecular Genetics

Hospital committee memberships

1999-present, Therapeutic Standards Committee
2006-present, Graduate Medical Education Committee
2008-present, Institutional Animal Care and Use Committee

Leadership

Memberships in professional organizations

International organizations

1996-present, North American Society for Pediatric Gastroenterology and Nutrition (World Congress of Pediatric Gastroenterology 2012, Taipei, Taiwan)

National organizations

1996-present, American Association for the Study of Liver Diseases

  • 2007-present, member, Pediatric Interest Group Steering committee
  • 2008-present, chair, Hepatology Training Working Group

1996-present, North American Society for Pediatric Gastroenterology, Hepatology and Nutrition

  • Member,  Hepatology Committee; representative to Hepatology Program Committee, World Congress of Pediatric Gastroenterology, 2012

1996-present, American Gastroenterological Association

  • 2009-present, Growth, Development and Aging Section nominating committee

National scientific committees

2006, 2007, 2008, 2010, Ad Hoc Reviewer, NIH Hepatobiliary Pathophysiology Study Section
2008, Ad Hoc Reviewer, NIH Pediatric Loan Repayment Program
2009, Ad Hoc Reviewer, NIH RC1 Challenge Grant Program

Original Papers

2010

Bales CB, Kamath BM, Munoz PS, Nguyen A, Piccoli DA, Spinner NB, et al. Pathologic lower extremity fractures in children with Alagille syndrome. J Pediatr Gastroenterol Nutr. 2010 Jul;51(1):66-70. Cited in PubMed; PMID 20453673. Read the abstract

Kamath BM, Loomes KM, Piccoli DA. Medical management of Alagille syndrome. J Pediatr Gastroenterol Nutr. 2010 Jun;50(6):580-6. Cited in PubMed; PMID 20479679. Read the abstract

Bauer RC, Laney AO, Smith R, Gerfen J, Morrissette JJ, Woyciechowski S, et al. Jagged1 (JAG1) mutations in patients with tetralogy of Fallot or pulmonic stenosis. Hum Mutat. 2010 May;31(5):594-601. Cited in PubMed; PMID 20437614.  Read the abstract »

2009

Colletti RB, Baldassano RN, Milov DE, Margolis PA, Bousvaros A, Crandall WV, et al. Variation in care in pediatric Crohn disease. J Pediatr Gastroenterol Nutr. 2009 Sep;49(3):297-303. Cited in PubMed; PMID 19590456. Read the abstract

High FA, Jain R, Stoller JZ, Antonucci NB, Lu MM, Loomes KM, et al. Murine Jagged1/Notch signaling in the second heart field orchestrates Fgf8 expression and tissue-tissue interactions during outflow tract development. J Clin Invest. 2009 Jul;119(7):1986-96. doi: 10.1172/JCI38922. Epub 2009 Jun 8. Cited in PubMed; PMCID: PMC2701882. Read the article

Golson ML, Le Lay J, Gao N, Brämswig N, Loomes KM, Oakey R, et al. Jagged1 is a competitive inhibitor of Notch signaling in the embryonic pancreas. Mech Dev. 2009 Aug-Sep;126(8-9):687-99. Epub 2009 Jun 6. Cited in PubMed; PMCID: PMC2728177. Read the article

Golson ML, Loomes KM, Oakey R, Kaestner KH. Ductal malformation and pancreatitis in mice caused by conditional Jag1 deletion. Gastroenterology. 2009 May;136(5):1761-71.e1. Epub 2009 Jan 23. Cited in PubMed; PMID 19208348. Read the abstract

Aitken JF, Loomes KM, Scott DW, Reddy S, Phillips AR, Prijic G, et al. Tetracycline treatment retards the onset and slows the progression of diabetes in human amylin/islet amyloid polypeptide transgenic mice.  Diabetes. 2010 Jan;59(1):161-71. Epub 2009 Sep 30. Read the article

Posters and Presentations

2011

Loomes KM. Academic careers in pediatrics [roundtable discussion]. Hopitaux Universitaires de Geneve, 2011 Mar; Geneva, Switzerland.

Loomes KM. Alagille syndrome: bench to bedside [presentation]. Grand Rounds, Department of Pediatrics, Hopitaux Universitaires de Geneve, 2011 Mar; Geneva, Switzerland.

Loomes KM.  The role of Jag1 in bile duct development and remodeling [presentation]. Department of Pediatrics Research Seminar, Monroe Carell Jr. Children's Hospital at Vanderbilt; 2011 Feb; Nashville, TN.

2010

Loomes KM. Neonatal cholestasis [presentation]. American Austrian Foundation, Course in Pediatric Gastroenterology; 2010 Oct; Salzburg, Austria.

Loomes KM. Viral and autoimmune hepatitis [presentation]. American Austrian Foundation, Course in Pediatric Gastroenterology; 2010 Oct; Salzburg, Austria.

Loomes KM. Metabolic liver disease [presentation]. American Austrian Foundation, Course in Pediatric Gastroenterology; 2010 Oct; Salzburg, Austria.

Loomes KM. Liver failure [presentation]. American Austrian Foundation, Course in Pediatric Gastroenterology; 2010 Oct; Salzburg, Austria.

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