Kim M. Olthoff, MD, is Associate Professor of Surgery in the Division of Transplantation at the University of Pennsylvania. She joined the surgical faculty at the University of Pennsylvania in 1995 and is currently Director of the Liver Transplant Program at the PENN Transplant Center and at the Children’s Hospital of Philadelphia. Dr. Olthoff received her medical degree from the University of Chicago in 1986, and completed a residency in general surgery at UCLA followed by a fellowship in transplantation and hepatobiliary surgery at the Dumont – UCLA Transplant Center. From there, she was recruited to help build the liver transplant programs at Penn and CHOP. The combined Liver Transplant Program at Penn and CHOP is currently one of the busiest clinical programs in the country, transplanting over 120 patients per year. The Penn program was recently named as the Top Performer for Transplant Benchmarking 2003 by the University HealthSystem Consortium for patient outcomes, operative statistics, resource utilization, and initiation of system pathways.
Dr. Olthoff is active in numerous national surgical societies, having served as an officer or councilor for several, such as the AAS and SUS. She also participates in many national and international transplant organizations. Dr. Olthoff is currently the regional Councilor and board member for the United Network for Organ Sharing (UNOS), Chair of the Awards committee and Councilor for the American Society of Transplant Surgery, and Councilor for the International Pediatric Transplantation Association. She has chaired the Liver and Intestinal Committee of the American Society of Transplantation, and was Vice Chair for the Membership and Professional Standards Committee for UNOS. She was recently honored as the Thomas E. Starzl Invited Lecturer at the American Association for the Study of Liver Diseases.
Dr. Olthoff has an active research laboratory in both basic and translational research and is a recipient of NIH funding for studies in liver regeneration, living donor transplantation, and immunologic monitoring studies in transplant recipients. She has authored or coauthored over 100 original papers and book chapters, serves on the editorial boards for Liver Transplantation, Pediatric Transplantation, and the Journal of Surgical Research, and is an editor of Pediatric Solid Organ Transplantation, 2nd ed (2005).
- Education and Training
MD - University of Chicago, Pritzker School of Medicine, Chicago, IL
Surgery - University of California School of Medicine, Los Angeles, CA
Surgery - University of California School of Medicine, Los Angeles, CA (Chief Resident)
Dumont-UCLA Transplant Center, Los Angeles, CA
- Titles and Academic Titles
Surgical Director, Liver Transplantation
Donald Guthrie Professor in Surgery, Perelman School of Medicine at the University of Pennsylvania
- Centers and Programs
Fine, RN, Webber SA, Olthoff KM, Kelly DA, Harmon WE, editors. Pediatric solid organ transplantation. 2nd ed. Malden (MA): Blackwell Publishing Ltd; 2007.
Porrett PM, Olthoff KM. Hepatectomy. In: Kanchwala S, Paulson EC, Roses R, Morris JM, editors. Gowned and gloved surgery: introduction to common procedures. Philadelphia: Saunders; 2008. p. 102-13.
Markmann JF, Yeh H, Naji A, Olthoff KM, Shaked A, Barker C. Transplantation of abdominal organs. In: Townsend CM, Beauchamp D, Evers M, Mattox KL, editors. Sabiston textbook of surgery. 18th ed. 2008. p. 692-733.
DeJonge J, Olthoff KM. Liver transplantation: liver regeneration. In: Gruessner RWG, Benedetti E, editors. Living donor organ transplantation. New York: McGraw-Hill; 2008. p. 459-67.
Olthoff K, Markmann J. The role of re-transplantation. In: Schiff ER, Sorrell MF, Maddrey WC, editors. Schiff's diseases of the liver. 10th ed. Philadelphia: Lippincott Williams & Wilkins; 2007. p. 1546-52.
Olthoff K. Liver regeneration. Clinical relevance. In: Blumgart LH, DeMatteo RP, editors. Surgery of the liver biliary tract and pancreas. 4th ed. Philadelphia: Elsevier; 2006. p. 54-62.
Desai NM, Olthoff KM. Portal vein thrombosis and other venous anomalies in liver transplantation. In: Busuttil RW, Klintmalm GB, editors. Transplantation of the liver. 2nd ed. Philadelphia: Saunders; 2005. p. 743-54.
Olthoff KM, Abt PL, Shaked A. Liver transplantation. In: Reddy KR, Long WB, editors. Requisites in gastroenterology; 2004. p. 243-55. (Hepatobiliary tract and pancreas; vol 3).
Rand EB, Olthoff KM. Overview of pediatric liver transplantation. In: Piccoli DA, guest ed. Gastroenterology clinics of North America: pediatric gastroenterology; 2003. p. 913-29. (Volume 32.)
Rand E, Olthoff KM. Pediatric liver transplantation. In: Lucey M, Neuberger J, Shaked A, editors. Liver transplantation. Austin: Landes Bioscience; 2002. p. 109-15.
Barker CF, Brayman KL, Markmann JF, Naji A, Olthoff KM, Shaked A. Transplantation of abdominal organs. In: Townsend CM, Beauchamp D, Evers BM, Mattox, editors. Sabiston textbook of surgery. 16th ed. Philadelphia: W.B. Saunders; 2001. p. 429-70.
Olthoff KM. Cadaver liver donor selection criteria. In: Norman D, Turka L, editors. Primer on transplantation. 2nd ed. Hoboken: Wiley-Blackwell; 2001. p. 536-39.
Tarek R, Olthoff K, Reilly PM. Issues in potential organ donor management. In: Schwab CW, Reilly PM, guest editors. The surgical clinics of North America. 3rd ed. 2000. p. 1021-32. (Volume 80.)
Nunes, FA, Olthoff KM, Lucey MR. Liver transplantation: indications and pretransplant evaluation. In: Bacon B, DiBisceglie, editors. Diseases of the liver. 1st ed. London: Churchill; 2000. p. 383-91.
Zamir GA, Olthoff KM, Nunes FA, Markmann JF, Zeldin GA, Stewart CA, et al. Liver transplantation at the University of Pennsylvania and the Children's Hospital of Philadelphia. In: Cecka PI, Terasaki JM, editors. Clinical transplants. Los Angeles: UCLA Tissue Typing Laboratory; 1999. p. 223-29.
Olthoff KM, Busuttil RW. Venous anomalies including portal vein thrombosis and prior portosystemic shunts. In: Busuttil RW, Klintmalm GB, editors. Transplantation of the liver. Philadelphia: W.B. Saunders; 1996. p. 46-47.
Olthoff KM, Busuttil RW. Liver transplantation in the management of portal hypertension. In: Ernst CB, Stanley JC, editors. Current therapy in vascular surgery. 3rd ed. Philadelphia: Mosby-Year Book, Inc.; 1995.
Olthoff KM, Brown SL, Busuttil RW. Portal hypertension. In: Moore WS, editor. Vascular surgery: a comprehensive review. 3rd ed. Orlando: W.B. Saunders Co.; 1990.
Millis JM, Olthoff KM, Imagawa DK, Baquerizo A, Busuttil RW. Liver transplantation at UCLA: a report of clinical activities. In: Terasaki PI, editor. Clinical transplants. Los Angeles: UCLA Tissue Typing Laboratory; 1988.
Abecassis MM, Fisher RA, Olthoff KM, Freise CE, Rodrigo DR, Samstein B, et al. Complications of living donor hepatic lobectomy — a comprehensive report. 2010. Am J Transplant. 2012 May;12(5):1208-17. doi: 10.1111/j.1600-6143.2011.03972.x. Epub 2012 Feb 15. Cited in PubMed; PMID 22335782. Read the abstract
Terrault NA, Roland ME, Schiano T, Dove L, Wong MT, Poordad F, et al. Outcomes of liver transplant recipients with hepatitis C and human immunodeficiency virus coinfection. Liver Transpl. 2012 Jun;18(6):716-26. doi: 10.1002/lt.23411. Cited in PubMed; PMID 22328294. Read the abstract
Friedman BH, Wolf JH, Wang L, Putt ME, Shaked A, Christie JD, et al. Serum cytokine profiles associated with early allograft dysfunction in patients undergoing liver transplantation. Liver Transpl. 2012 Feb;18(2):166-76. doi: 10.1002/lt.22451. Cited in PubMed; PMID 22006860. Read the abstract
Berg CL, Merion RM, Shearon TH, Olthoff KM, Brown RS Jr, Baker TB, et al. Liver transplant recipient survival benefit with living donation in the model for endstage liver disease allocation era. Hepatology. 2011 Oct;54(4):1313-21. doi: 10.1002/hep.24494. Cited in PubMed; PMCID: PMC3184197. Read the article
Bacon BR, Adams PC, Kowdley KV, Powell LW, Tavill AS; American Association for the Study of Liver Diseases. Diagnosis and management of hemochromatosis: 2011 practice guideline by the American Association for the Study of Liver Diseases. Hepatology. 2011 Jul;54(1):328-43. doi: 10.1002/hep.24330. Cited in PubMed; PMCID: PMC3149125. Read the article
Trotter JF, Gillespie BW, Terrault NA, Abecassis MM, Merion RM, Brown RS Jr, et al. Laboratory test results after living liver donation in the adult-to-adult living donor liver transplantation cohort study. Liver Transpl. 2011 Apr;17(4):409-17. doi: 10.1002/lt.22246. Cited in PubMed; PMID PMCID: PMC3295864. Read the article
Mendizabal M, Reddy KR, Cassuto J, Olthoff KM, Faust TW, Makar GA, et al. Liver transplantation in patients with cystic fibrosis: analysis of United Network for Organ Sharing data. Liver Transpl. 2011 Mar;17(3):243-50. doi: 10.1002/lt.22240. Cited in PubMed; PMID 21384506. Read the article
Olthoff KM, Abecassis MM, Emond JC, Kam I, Merion RM, Gillespie BW, et al. Outcomes of adult living donor liver transplantation: comparison of the Adult-to-adult Living Donor Liver Transplantation Cohort Study and the national experience. Liver Transpl. 2011 Jul;17(7):789-97. doi: 10.1002/lt.22288. Cited in PubMed; PMID 21360649.Read the article
Florence LS, Feng S, Foster CE 3rd, Fryer JP, Olthoff KM, Pomfret E, et al. Academic careers and lifestyle characteristics of 171 transplant surgeons in the ASTS. Am J Transplant. 2011 Feb;11(2):261-71. doi: 10.1111/j.1600-6143.2010.03381.x. Epub 2011 Jan 10. Cited in PubMed; PMID 21219568. Read the abstract
Olthoff KM. The grading of donor complications: GPAs or pass/fail? Am J Transplant. 2011 Jan;11(1):11-2. doi: 10.1111/j.1600-6143.2010.03377.x. Cited in PubMed; PMID 21199344. No abstract available.
Kiefer MV, Albert M, McNally M, Robertson M, Sun W, Fraker D, et al. Chemoembolization of intrahepatic cholangiocarcinoma with cisplatinum, doxorubicin, mitomycin C, ethiodol, and polyvinyl alcohol: a 2-center study. Cancer. 2010 Nov 8. Read the abstract.
Bunin N, Guzikowski V, Rand ER, Goldfarb S, Baluarte J, Meyers K, et al. Solid organ transplants following hematopoietic stem cell transplant in children. Pediatr Transplant. 2010 Dec;14(8):1030-5. doi: 10.1111/j.1399-3046.2010.01401.x. Epub 2010 Sep 15. Read the abstractChapman R, Fevery J, Kalloo A, Nagorney DM, Boberg KM, Shneider B, et al. Diagnosis and management of primary sclerosing cholangitis. Hepatology. 2010 Feb;51(2):660-78. No abstract available.
Olthoff KM, Kulik L, Samstein B, Kaminski M, Abecassis M, Emond J, et al. Validation of a current definition of early allograft dysfunction in liver transplant recipients and analysis of risk factors. Liver Transpl. 2010 Aug;16(8):943-9. Read the abstract
Merion RM, Shearon TH, Berg CL, Everhart JE, Abecassis MM, Shaked A, et al. Hospitalization rates before and after adult-to-adult living donor or deceased donor liver transplantation. Ann Surg. 2010 Mar;251(3):542-9. Read the abstract
- Editorial and Academic Positions
2011-present, Liver Transplantation
2009-2011, Associate Editor, Liver Transplantation
Journal of Gastroenterology
Annals of Surgery
American Journal of Transplantation
Journal of Hepatology
Journal of Immunology
Academic and institutional committees
2008-present, Professionalism Committee for the School of Medicine, Perelman School of Medicine at the University of Pennsylvania
2008-present, School of Medicine Committee on Appointments and Promotions, Perelman School of Medicine at the University of Pennsylvania
2007-present, Department of Surgery Committee on Appointments and Promotions, Perelman School of Medicine at the University of Pennsylvania
1997-present, Faculty Advisory Committee, Perelman School of Medicine at the University of Pennsylvania
1997-present, Clinical Pathway Committee, Perelman School of Medicine at the University of Pennsylvania
1995-present, Residency Review Committee, Perelman School of Medicine at the University of Pennsylvania
- Editorial and Academic Positions