William H. Peranteau, MD

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William H. Peranteau, MD, is an attending surgeon in the Division of General, Thoracic and Fetal Surgery at Children's Hospital of Philadelphia. He holds the Adzick-McCausland Distinguished Chair in Fetal and Pediatric Surgery.

Locations: Main Hospital; Buerger Center for Advanced Pediatric Care

Appointments and Referrals: 215-590-2730

Background

Dr. William Hughes Peranteau is an attending surgeon in the Division of Pediatric General, Thoracic and Fetal Surgery at Children’s Hospital of Philadelphia (CHOP) and an associate professor of surgery at the Perelman School of Medicine at the University of Pennsylvania.

His areas of interest include fetal biology, fetal and neonatal surgery, and general pediatric surgery. A native of Gloucester City, New Jersey, just 10 miles east of CHOP’s Main campus, Dr. Peranteau earned his bachelor’s degree in molecular biology from Princeton University, and his medical degree from the University of Pennsylvania.

“CHOP is unique in that it integrates cutting-edge basic science research with the largest fetal care center in the world, offering a multidisciplinary team of experts that have advanced the field and will continue to advance the field into the future,” he says. “I’m very lucky to have grown up in this area, and now, to be able to practice pediatric surgery at the best possible place and be involved in such an exciting research community here is awesome.”

Prior to joining the Center team in 2012, Dr. Peranteau completed his residency in general surgery at Brigham and Women’s Hospital, Boston, Mass., and a fellowship in pediatric general surgery at CHOP. He also served as a research fellow with CHOP’s Center for Fetal Research for four years, investigating the role of in utero bone marrow and stem cell transplantation for the management of congenital hematologic disorders such as sickle cell disease.

“This area of research is potentially readily translatable to clinical application,” Dr. Peranteau says. “The group of people not only within the Department of Pediatric General Surgery and the Richard D. Wood Jr. Center for Fetal Diagnosis and Treatment (CFDT) but also the CHOP community as a whole, with experts in every field of pediatrics, make CHOP an unbelievable place to work and a place that’s ripe for advancing clinical medicine.”

Dr. Peranteau has published articles in the Journal of the American College of Surgeons, the Journal of Pediatric Surgery, Fetal Diagnosis and Therapy, Experimental Hematology and Blood. He is board certified in pediatric surgery and general surgery.

To contact the Richard D. Wood Jr. Center for Fetal Diagnosis and Treatment, call 1-800-468-8376 (1-800-IN-UTERO).

Education and Training

Medical School

MD — University of Pennsylvania School of Medicine, Philadelphia, PA

Internship

General Surgery — Brigham and Women's Hospital, Boston, MA

Residency

General Surgery — Brigham and Women's Hospital, Boston, MA

Fellowship

Research — The Children's Hospital of Philadelphia, Philadelphia, PA
Pediatric Surgery — The Children's Hospital of Philadelphia, Philadelphia, PA

Board Certification

General Surgery – American Board of Surgery
Pediatric Surgery – American Board of Surgery

Titles and Academic Titles

Attending Surgeon

Adzick-McCausland Distinguished Chair in Fetal and Pediatric Surgery

Associate Professor of Surgery, Perelman School of Medicine at the University of Pennsylvania

Conditions Treated

Departments and Services

Publications

Papers

2020

Gene and Stem Cell Therapies for Fetal Care: A Review. O'Connell AE, Guseh S, Lapteva L, Cummings CL, Wilkins-Haug L, Chan J, Peranteau WH, Almeida-Porada G, Kourembanas S. JAMA Pediatr. 2020 Jun 29.doi: 10.1001/jamapediatrics.2020.1519. Online ahead of print.

Two's Company: Multiple Thoracic Lesions on Prenatal US and MRI. Oliver ER, DeBari SE, Didier RA, Johnson AM, Khalek N, Peranteau WH, Howell LJ, Adzick NS, Coleman BG. Fetal Diagn Ther. 2020 Jun 29;1-11. doi: 10.1159/000507783. Online ahead of print.

2019

Alapati D, Zacharias WJ, Hartman HA, Rossidis AC, Stratigis JD, Ahn NJ, Coons B, Zhou S, Li H, Singh K, Katzen J, Tomer Y, Chadwick AC, Musunuru K, Beers MF, Morrisey EE, Peranteau WH. In utero gene editing for monogenic lung disease. Science Translational Medicine. 2019 April 17; Vol. 11, Issue 488. doi: 10.1126/scitranslmed.aav8375.

Rossidis AC, Angelin A, Lawrence KM, Baumgarten HD, Kim AG, Mejaddam AY, Coons BE, Hartman HA, Hwang G, Monos S, Peranteau WH, Davey MG, Murdock D, Wallace DC, Flake AW. Premature Lambs Exhibit Normal Mitochondrial Respiration after Long-Term Extrauterine Support. Fetal Diagn Ther. 2019 Mar 12;:1-7. PMID: 30861524

Almeida-Porada G, Waddington SN, Chan JKY, Peranteau WH, MacKenzie T, Porada CD. In Utero Gene Therapy Consensus Statement from the IFeTIS. Mol Ther. 2019 Mar 2;. PMID: 30837116 

Mejaddam AY, Hornick MA, McGovern PE, Baumgarten HD, Lawrence KM, Rossidis AC, Hwang G, Young K, Abdulmalik O, Partridge EA, Peranteau WH, Davey MG, Flake AW. Erythropoietin Prevents Anemia and Transfusions in Extremely Premature Lambs Supported by an EXTrauterine Environment for Neonatal Development (EXTEND). Fetal Diagn Ther. 2019 Jan 31;:1-7. PMID: 30703769 

Lawrence KM, McGovern PE, Mejaddam A, Rossidis AC, Baumgarten H, Kim A, Grinspan JB, Licht DJ, Didier RA, Vossough A, Radaelli E, Rychik J, Song L, Peranteau WH, Davey MG, Flake AW, Gaynor JW. Chronic intrauterine hypoxia alters neurodevelopment in fetal sheep. J Thorac Cardiovasc Surg. 2019 Jan 11;. PMID: 30745051 

Pogoriler J, Swarr D, Krieger P, Adzick NS, Peranteau WH: Congenital cystic lung lesions: Redefining the natural distribution of subtypes and risk of malignancy.  Am J Surg Pathology 43:47-55, 2019.

2018

Lawrence KM, Hennessy-Strahs S, McGovern PE, Mejaddam AY, Rossidis AC, Baumgarten HD, Bansal E, Villeda M, Han J, Gou Z, Zhao S, Rychik J, Peranteau WH, Davey MG, Flake AW, Gaynor JW, Bartoli CR. Fetal hypoxemia causes abnormal myocardial development in a preterm ex utero fetal ovine model. JCI Insight. 2018;3(24).

Fraga MV, Laje P, Peranteau WH, Hedrick HL, Khalek N, Gebb JS, Moldenhauer JS, Johnson MP, Flake AW, Adzick NS: The influence of gestational age, delivery mode, and abdominal wall closure method in neonates with uncomplicated gastroschisis.  Pediatr Surg Int 34:415-9, 2018.

Danzer E, Hoffman C, D'Agostino J, Ryan M, Gerdes M, Bernbaum J, Rintoul NE, Herkert LM, Peranteau WH, Flake AW, Adzick NS, Hedrick HL: Rate and risk factors associated with autism spectrum disorder in congenital diaphragmatic hernia.  Journal of Autism and Developmental Disorders48:2112-2121, 2018. 

Danzer E, Hoffman C, D’Agostino JA, Boelig MM, Gerdes M, Bernbaum J, Rosenthal H, Waqar LN, Rintoul NE, Herkert LM, Kallan MJ, Peranteau WH, Flake AW, Adzick NS, Hedrick HL: Short-term neurodevelopmental outcome in children born with high-risk congenital lung lesions. Annals of Thoracic Surgery 105:1827-1834, 2018.

Danzer E, Hoffman C, D'Agostino J, Connelly JT, Waqar LN, Gerdes M, Bernbaum J, Rintoul NE, Herkert LM, Peranteau WH, Flake AW, Adzick NS, Hedrick HL: Short-term neurodevelopmental outcome in congenital diaphragmatic hernia: The impact of extracorporeal membrane oxygenation and timing of repair. Pediatric Critical Care Medicine 19:64-74, 2018.

Riley JS, Urwin JW, Oliver ER, Coleman BG, Khalek N, Moldenhauer JS, Gebb J, Hedrick HL, Spinner SS, Adzick NS, Peranteau WH: Prenatal growth characteristics and pre/postnatal management of bronchopulmonary sequestrations. J Pediatr Surg 53:265-269, 2018. 

Ahn NJ, Stratigis JD, Coons BE, Flake AW, Nah-Cederquist HD, Peranteau WH. Intravenous and Intra-amniotic In Utero Transplantation in the Murine Model. J Vis Exp. 2018 Oct 9;(140).

Rossidis AC, Stratigis JD, Chadwick AC, Hartman HA, Ahn NJ, Li H, Singh K, Coons BE, Li L, Lv W, Zoltick PW, Alapati D, Zacharias W, Jain R, Morrisey EE, Musunuru K, Peranteau WH. In utero CRISPR-mediated therapeutic editing of metabolic genes. Nat Med. 2018 Oct;24(10):1513-1518. Epub 2018 Oct 8.

Lawrence KM, Berger K, Herkert L, Franciscovich C, O'Dea CLH, Waqar LN, Partridge E, Hanna BD, Peranteau WH, Avitabile CM, Hopper RK, Rintoul NE, Hedrick HL. Use of prostaglandin E1 to treat pulmonary hypertension in congenital diaphragmatic hernia. J Pediatr Surg. 2018 Oct 5;. PMID: 30442461

Riley JS, McClain LE, Stratigis JD, Coons BE, Li H, Hartman HA, Peranteau WH. Pre-Existing Maternal Antibodies Cause Rapid Prenatal Rejection of Allotransplants in the Mouse Model of In Utero Hematopoietic Cell Transplantation. J Immunol. 2018 Jul 18; PMID: 30021770

Victoria T, Srinivasan AS, Pogoriler J, Kreiger PA, Laje P, Oliver ER, Danzer E, Johnson AM, Moldenhauer JS, Peranteau WH, Adzick NS. The rare solid fetal lung lesion with T2-hypointense components: prenatal imaging findings with postnatal pathological correlation. Pediatr Radiol. 2018 Jul 14; PMID: 30008034

Rossidis AC, Baumgarten HD, Lawrence KM, McGovern PE, Mejaddam AY, Li H, Hwang G, Young K, Peranteau WH, Davey MG, Gaynor JW, Flake AW. Chronically Hypoxic Fetal Lambs Supported by an Extra-Uterine Device Exhibit Mitochondrial Dysfunction and Elevations of Hypoxia Inducible Factor 1-Alpha. Fetal Diagn Ther. 2018 Jun 28; 1-8. [Epub ahead of print]

Riley JS, Antiel RM, Rintoul NE, Ades AM, Waqar LN, Lin N, Herkert LM, D'Agostino JA, Hoffman C, Peranteau WH, Flake AW, Adzick NS, Hedrick HL. Reduced oxygen concentration for the resuscitation of infants with congenital diaphragmatic hernia. J Perinatol. 2018 Jun 11. [Epub ahead of print]

Lawrence KM, Hedrick HL, Monk HM, Herkert L, Waqar LN, Hanna BD, Peranteau WH, Rintoul NE, Hopper RK. Treprostinil Improves Persistent Pulmonary Hypertension Associated with Congenital Diaphragmatic Hernia. J Pediatr. 2018 May 18;. [Epub ahead of print] PMID: 29784517 

Baumgarten HD, Gebb JS, Khalek N, Moldenhauer JS, Johnson MP, Peranteau WH, Hedrick HL, Adzick NS, Flake AW. Preemptive Delivery and Immediate Resection for Fetuses with High-Risk Sacrococcygeal Teratomas. Fetal Diagn Ther. 2018 May 7;:1-8. [Epub ahead of print] PMID: 29734172 

Victoria T, Andronikou S, Bowen D, Laje P, Weiss DA, Johnson AM, Peranteau WH, Canning DA, Adzick NS. Fetal anterior abdominal wall defects: prenatal imaging by magnetic resonance imaging. Pediatr Radiol. 2018 Apr;48(4):499-512. PMID: 29550866 

Gebb JS, Khalek N, Qamar H, Ozcan T, Johnson MP, Oliver ER, Coleman BG, Peranteau WH, Hedrick HL, Flake AW, Adzick NS, Moldenhauer JS: High tumor volume to fetal weight ratio is associated with worse fetal outcomes and increased maternal risks in fetuses with sacrococcygeal teratoma. Fetal Diagn Ther. 2019;45(2):94-101. doi: 10.1159/000486782. Epub 2018 Mar 1.

Partridge EA, Davey MG, Hornick M, Dysart KC, Olive A, Caskey R, Connelly JT, Hedrick HL, Peranteau WH, Flake AW. Pumpless arteriovenous extracorporeal membrane oxygenation: A novel mode of respiratory support in a lamb model of congenital diaphragmatic hernia. J Pediatr Surg. 2018 Mar 9;. [Epub ahead of print] PMID: 29605270 

Laje P, Fraga MV, Peranteau WH, Hedrick HL, Khalek N, Gebb JS, Moldenhauer JS, Johnson MP, Flake AW, Adzick NS. Complex gastroschisis: Clinical spectrum and neonatal outcomes at a referral center. J Pediatr Surg. 2018 Mar 14;. [Epub ahead of print] PMID: 29628208

Swarr DT, Peranteau WH, Pogoriler J, Frank DB, Adzick NS, Hedrick HL, Morley M, Zhou S, Morrisey EE. Novel Molecular and Phenotypic Insights into Congenital Lung Malformations. Am J Respir Crit Care Med. 2018 Jan 12. doi: 10.1164/rccm.201706-1243OC. [Epub ahead of print] PubMed PMID: 29328793.

Victoria T, Danzer E, Oliver ER, Edgar JC, Iyoob S, Partridge EA, Johnson AM, Peranteau WH, Coleman BG, Flake AW, Johnson MP, Hedrick HL, Adzick NS: Right congenital diaphragmatic hernias: Is there a correlation between prenatal lung volume and postnatal survival, as in isolated left diaphragmatic hernias? Fetal Diagnosis and Therapy 2018; 43: 12-18, January 2018.

2017

Peranteau WH, Iyoob SD, Boelig MM, Khalek N, Moldenhauer JS, Johnson MP, Hedrick HL, Flake AW, Coleman BG, Adzick NS. Prenatal growth characteristics of lymphatic malformations. J Pediatr Surg. 2017 Jan;52(1):65-68.

Emily A. Partridge, Marcus G. Davey, Matthew A. Hornick, Patrick E. McGovern, Ali Y. Mejaddam, Jesse D. Vrecenak, Carmen Mesas-Burgos, Aliza Olive, Robert C. Caskey, Theodore R. Weiland III, Jiancheng Han, James T. Connelly, Kevin C. Dysart, Alexander J. Schupper, Jack Rychik, Holly L. Hedrick, William H. Peranteau, and Alan W. Flake. An extra-uterine physiologic support system for the extreme premature lamb. Nature Communications. Published online April 25, 2017.

Partridge EA, Davey MG, Hornick MA, McGovern PE,  Mejaddam AY, Vrecenak JD, Mesas-Burgos C, Olive A, Caskey RC, Weiland TR, Han J, Schupper AJ, Connelly JT, Dysart KC, Rychik J, Hedrick HL, Peranteau WH, Flake AW. Corrigendum: An extra-uterine system to physiologically support the extreme premature lamb. Nat Commun. 2017 May 23;8:15794. Doi: 10.1038/ncomms15794. 

Antiel RM, Halpem SD, Stevens EM, Vrecenak JD, Patterson CA, Tchume-Johnson T, Smith-Whitley K, Peranteau WH, Flake AW, Baraket LP. Acceptability of In Utero Hematopoietic Cell Transplantation for Sickle Cell Disease. Med Decis Making. 2017 May 1:272989X17707214. Doi: 10.1177/0272989x17707214. [Epub ahead of print].

Witt R, Mackenzie TC, Peranteau WH. Fetal stem cell and gene therapy. Semin Fetal Neonatal Med. 2017 Jun 12. Pii: S1744-165X(17)30050-1. Doi: 10.1016/j.siny.2017.05.003. [Epub ahead of print] Review.

Kim AG, Danzer E, Moldenhauer JS, Khalek N, McClain LE, Waqar LN, Hedrick HL, Johnson MP, Adzick NS, Peranteau WH, Flake AW. Amniotic Fluid Concentrations of Glial Fibrillary Acidic Protein Do Not Correlate with Prenatal Metrics in Fetuses with Myelomeningocele. Fetal Diagn Ther. 2017 Jul 29. Doi: 10.1159/000478258. [Epub ahead of print].

Burgos CM, Davey MG, Riley JS, Jia H, Flake AW, Peranteau WH. Lung function and pulmonary artery blood flow following prenatal maternal retinoic acid and imatinib in the nitrofen model of congenital diaphragmatic hernia. J Pediatr Surg. 2018 Sep;53(9):1681-1687. Epub 2017 Dec 19.

2016

Burgos CM, Pearson EG, Davey M, Riley J, Jia H, Laje P, Flake AW, Peranteau WH. Improved pulmonary function in the nitrofen model of congenital diaphragmatic hernia following prenatal maternal dexamethasone and/or sildenafil. Pediatr Res. 2016 Oct;80(4):577-85.

Danzer E, Gerdes M, D’Agostino JA, Bernbaum J, Hoffman C, Herkert LM, Rintoul NE, Peranteau WH, Flake AW, Adzick NS, Hedrick HL. Younger gestational age is associated with increased risk of adverse neurodevelopmental outcome during infancy in congenital diaphragmatic hernia. J Pediatr Surg. 2016 Jul;51(7):1084-90.

Partridge EA, Peranteau WH, Herkert L, Rendon N, Smith H, Rintoul NE, Flake AW, Adzick NS, Hedrick HL. Right- versus left-sided congenital diaphragmatic hernia: a comparative outcomes analysis. J Pediatr Surg. 2016 Jun;51(6):900-2.

Partridge EA, Peranteau WH, Herkert L, Rintoul NE, Flake AW, Adzick NS, Hedrick HL. Rate of increase of lung-to-head ratio over the course of gestation is predictive of survival in left-sided congenital diaphragmatic hernia. J Pediatr Surg. 2016 May;51(5):703-5.

Peranteau WH, Adzick NS. Prenatal surgery for myelomeningocele. Curr Opin Obstet Gynecol. 2016 Apr;28(2):111-8.

Jump C, Anupindi S, Peranteau W, Dunham B, Mamula P. Extensive Thoracic Injury From Button Battery Ingestion. J Pediatr Gastroenterol Nutr. 2016 Mar;62(3):e24.

Laje P, Hedrick HL, Flake AW, Adzick NS, Peranteau WH. Delayed abdominal closure after congenital diaphragmatic hernia repair. J Pediatr Surg. 2016 Feb;51(2):240-3.

Peranteau WH, Boelig MM, Khalek N, Moldenhauer JS, Martinez-Poyer J, Hedrick HL, Flake AW, Johnson MP, Adzick NS. Effect of single and multiple courses of maternal betamethasone on prenatal congenital lung lesion growth and fetal survival. J Pediatr Surg. 2016 Jan;51(1):28-32.

Antiel RM, Riley JS, Cahill PJ, Campbell RM, Waqar L, Herkert LM, Rintoul NE, Peranteau WH, Flake AW, Adzick NS, Hedrick HL. Management and outcomes of scoliosis in children with congenital diaphragmatic hernia. J Pediatr Surg. 2016;51(12):1921-1925. 

2015

Laje P, Hedrick HL, Flake AW, Adzick NS, Peranteau WH. Delayed abdominal closure after congenital diaphragmatic hernia repair. J Pediatr Surg. 2015 Nov 11.

Peranteau WH, Boelig MM, Khalek N, Moldenhauer JS, Martinez-Poyer J, Hedrick HL, Flake AW, Johnson MP, Adzick NS. Effect of single and multiple courses of maternal betamethasone on prenatal congenital lung lesion growth and fetal survival. J Pediatr Surg. 2015 Oct 23.

Partridge EA, Peranteau WH, Flake AW, Adzick NS, Hedrick HL. Frequency and complications of inguinal hernia repair in giant omphalocele. J Pediatr Surg. 2015 Oct.

Peranteau WH, Tharakan SJ, Partridge E, Herkert L, Rintoul NE, Flake AW, Adzick NS, Hedrick HL. Systemic hypertension in giant omphalocele: An underappreciated association. J Pediatr Surg. 2015 Sep;50(9):1477-80.

Moldenhauer JS, Soni S, Rintoul NE, Spinner SS, Khalek N, Martinez-Poyer J, Flake AW, Hedrick HL, Peranteau WH, Rendon N, Koh J, Howell LJ, Heuer GG, Sutton LN, Johnson MP, Adzick NS. Fetal Myelomeningocele Repair: The Post-MOMS Experience at the Children's Hospital of Philadelphia. Fetal Diagn Ther. 2015;37(3):235-40. Epub 2014 Aug 15.

Danzer E, Gerdes M, D'Agostino JA, Bernbaum J, Hoffman C, Herkert L, Rintoul NE, Peranteau WH, Flake AW, Adzick NS, Hedrick HL. Neurodevelopmental outcome at one year of age in congenital diaphragmatic hernia infants not treated with extracorporeal membrane oxygenation. J Pediatr Surg. 2015 Jun;50(6):898-903. doi: 10.1016.

Laje P, Peranteau WH, Hedrick HL, Flake AW, Johnson MP, Moldenhauer JS, Adzick NS. Ex utero intrapartum treatment (EXIT) in the management of cervical lymphatic malformation. J Pediatr Surg. 2015 Feb;50(2):311-4. doi: 10.1016/j.jpedsurg.2014.11.024. Epub 2014 Nov 10.

Partridge EA, Peranteau WH, Rintoul NE, Herkert LM, Flake AW, Adzick NS, Hedrick HL. Timing of repair of congenital diaphragmatic hernia in patients supported by extracorporeal membrane oxygenation (ECMO). J Pediatr Surg. 2015 Feb;50(2):260-2.

Peranteau WH, Scott Adzick N, Boelig MM, Alan W F, Hedrick HL, Howell LJ, Moldenhauer JS, Khalek N, Martinez-Poyer J, Johnson MP. Thoracoamniotic shunts for the management of fetal lung lesions and pleural effusions: a single-institution review and predictors of survival in 75 cases. J Pediatr Surg. 2015 Feb;50(2):301-5.

Partridge EA, Hanna BD, Rintoul NE, Herkert L, Flake AW, Adzick NS, Hedrick HL, Peranteau WH. Brain-type natriuretic peptide levels correlate with pulmonary hypertension and requirement for extracorporeal membrane oxygenation in congenital diaphragmatic hernia. J Pediatr Surg. 2015 Feb;50(2):263-6.

Peranteau WH, Tharakan SJ, Partridge E, Herkert L, Rintoul NE, Flake AW, Adzick NS, Hedrick HL. Systemic hypertension in giant omphalocele: An underappreciated association. J Pediatr Surg. 2015 Feb 23. pii: S0022-3468(15)00131-1. doi: 10.1016. 

2014

Vrecenak JD, Howell LJ, Khalek N, Moldenhauer JS, Johnson MP, Coleman BG, Victoria T, Hedrick HL, Peranteau WH, Flake AW, Adzick NS. Outcomes of prenatally diagnosed lung lesions in multigestational pregnancies. Fetal Diagn Ther. 2014 Dec;36(4):312-9.

Partridge EA, Hanna BD, Panitch HB, Rintoul NE, Peranteau WH, Flake AW, Adzick NS, Hedrick HL. Pulmonary hypertension in giant omphalocele infants. J Pediatr Surg. 2014 Dec;49(12):1767-70.

Partridge EA, Bridge C, Donaher JG, Herkert LM, Grill E, Danze8. Peranteau WH, Moldenhauer JS, Khalek N, Martinez-Poyer JL, Howell LJ, Johnson MP, Flake AW, Adzick NS, Hedrick HL. Open fetal surgery for central bronchial atresia. Fetal Diagn Ther. 2014;35(2):141-7.r E, Gerdes M, Hoffman CH, D’Agostino JA, Bernbaum JC, Rintoul NE, Peranteau WH, Flake AW, Adzick NS, Hedrick HL. Incidence and factors associated with sensorineural and conductive hearing loss among survivors of congenital diaphragmatic hernia. J Pediatr Surg. 2014 Jun;49(6):890-4.

Partridge EA, Canning D, Long C, Peranteau WH, Hedrick HL, Adzick NS, Flake AW. Urologic and anorectal complications of sacrococcygeal teratomas: prenatal and postnatal predictors. J Pediatr Surg. 2014 Jan;49(1):139-43.

2013

Peranteau WH, Palladino AA, Bhatti TR, Becker SA, States LJ, Stanley CA, Adzick NS. The surgical management of insulinomas in children. J Pediatr Surg. 2013 Dec;48(12):2517-24. 

Peranteau WP, Palladino AA, Bhatti TR, States L, Stanley CA, Adzick NS: The surgical management of insulinomas in children. J Pediatr Surg 48:2517-2524, 2013.

2010

Endo M, Henriques-Coelho T, Zoltick PW, Stitelman DH, Peranteau WH, Radu A, et al. The developmental stage determines the distribution and duration of gene expression after early intraamniotic gene transfer using lentiviral vectors. Gene Ther. 2010 Jan;17(1):61-71. Epub 2009 Sep 3. Cited in PubMed; PMID 19727133.

Peranteau WH, Havens JM, Harrington S, Gates JD. Reestablishing surgical care at Port au Prince General Hospital, Haiti. J Am Coll Surg. 2010 Jul;211(1):126-30. Epub 2010 May 26. Cited in PubMed; PMID 20610258. No abstract available.

2007

Peranteau WH, Bathaii SM, Pawel B, Hardy O, Alavi A, Stanley CA, Adzick NS: Multiple ectopic lesions of focal islet adenomatosis identified by PET scan in an infant with congenital hyperinsulinism. J Pediatr Surg 42:188-192, 2007.

2006

Peranteau WH, Ganguly A, Steinmiller L, Thornton P, Johnson MP, Howell LJ, Adzick NS, Stanley CA: Prenatal diagnosis and postnatal management of diffuse congenital hyperinsulinism: A case report. Fetal Diagnosis and Therapy 21:515-518, 2006. 

Abstracts

2017

John Riley, John Urwin, Edward Oliver, Beverly Coleman, Mark Johnson, Nahla Khalek, Julie Moldenhauer, Juliana Gebb, Lori Howell, Holly Hedrick, Alan Flake, N. Scott Adzick, William Peranteau. “Prenatal Growth Characteristics and Pre/postnatal Management of Prenatally-diagnosed Extralobar Bronchopulmonary Sequestrations.” British Association of Pediatric Surgeons 64th Annual Scientific Meeting in London, July 2017. Winner of Peter Paul Rickham Prize (Basic Science) and President’s Prize (Clinical)

Books

Chapters

2022

Peranteau, W.H. (2022). Congenital Lung Lesions. In: Mattei, P. (eds) Fundamentals of Pediatric Surgery. Springer, Cham. https://doi.org/10.1007/978-3-031-07524-7_42

2019

Madenci AL. Peranteau WH. Smink DS. Appendix and Small Bowel Diverticula. In: Maingot’s Abdominal Operations 13th Ed. New York (NY): McGraw Hill Medical; 2019.

Ahn NJ. Peranteau WH. Sacrococcygeal Teratoma. In: Operative Techniques in Plastic Surgery 1st Ed. Philadelphia (PA): Wolters Kluwer; 2019.

Rossidis AC. Hartman HA. Peranteau W. Gene Therapy. In: Pediatric Surgery NaT. American Pediatric Surgery Association; pedsurgerylibrary.com; 2019.

2016

Peranteau WH. Sacrococcygeal Teratomas. In: Fundamentals of Pediatric Surgery 2nd Ed. New York (NY): Springer; 2016.

2014

Peranteau WH. Mattei PA. Hernias. In: Comprehensive Pediatric Hospital Medicine 2nd Ed. New York (NY): McGraw Hill Medical; 2014.

Peranteau WH. Mattei PA. Hirschprung’s Disease. In: Pediatric Gastrointestinal and Liver Disease 5th Ed. Philadelphia (PA): Elsevier Saunders; 2014.

2013

Peranteau WH. Smink DS. Appendix, Meckel’s, and Other Small Bowel Diverticula. In: Maingot’s Abdominal Operations 12th Ed. New York (NY): McGraw Hill Medical; 2013.

2001

Karlawish JHT, Peranteau WH. Genetic Screening in General Internal Medicine. In: Genetics in the Clinic: Clinical, Ethical, and Social Implications for Primary Care. St Louis (MO): Mosby; 2001. p. 181-187.

Awards and Honors

2019-2024, NIH Director’s New Innovator Award; NIH Common Fund’s High Risk, High Reward Program
2019-2020, University of Pennsylvania, Institute for Translational Medicine and Therapeutics Collaborative Research Award
2017-2018, University of Pennsylvania, Institute for Translational Medicine and Therapeutics Collaborative Research Award
2016-2017, The Orphan Disease Center Genome Editing for the Treatment of Rare Diseases Pilot Grant Award
2015-2016, American Pediatric Surgical Association Foundation Award
2015-2016, Protective Immunity and Immunopathology Affinity Group Pilot Grant Award, The Children’s Hospital of Philadelphia
2013-2016, The Gerber Foundation Novice Research Award
2013-2015, The Gerber Foundation Novice Research Award
2010, Robert T. Osteen Teaching Award, Brigham & Women's Hospital/Harvard Medical School
2008, 2010, Surgery Resident Teaching Award, Tufts University School of Medicine
2007, John A. Mannick Research Award, Brigham & Women's Hospital
2006, The Children's Hospital of Philadelphia Annual Research Award
2002, I.S. Ravdin Award, University of Pennsylvania School of Medicine
1997-present, Phi Beta Kappa Academic Honor Society
1997-present, Sigma Xi Scientific Honor Society
1997, All Academic Team, NCAA Division I Swimming & Diving, Princeton University
1997, NCAA Postgraduate Scholarship, Princeton University
1997, War Memorial Trophy for Outstanding Contribution to the Sport of Swimming, Princeton University
1996, Jabez Pierson Pennington Memorial Scholarship for Outstanding Academic Achievement, Princeton University
1996, All Academic Team, Honorable Mention, NCAA Division I Swimming & Diving, Princeton University
1994-1997, All-Ivy-League Academic Honors, Men's Swimming and Diving, Princeton University
1994, William Pierson-Hibben Memorial Scholarship for Outstanding Scholarship, Character and Promise, Princeton University

Editorial and Academic Positions

Editorial positions

2019-present, Ad Hoc Reviewer, Nature Medicine
2016-present, Ad Hoc Reviewer, PLoS One
2015-present, Ad Hoc Reviewer, Frontiers in Pharmacology
2015-present, Ad Hoc Reviewer, Journal of Pediatric Surgery

Academic and Institutional Committees

2019-present, Penn-CHOP Lung Biology Institute (LBI)
2019-present, Research Pillar Steering Committee
2019-present, Cell and Gene Therapy Strategy Executive Committee
2017-present, Participant in Center for Undergraduate Research and Fellowships (CURF), University of Pennsylvania
2016-present, Participant in Center for Undergraduate Research and Fellowships (CURF), University of Pennsylvania
2014-present, General Surgery and The Center for Fetal Diagnosis and Treatment Research Committee
2013-present, Alumni Organization Executive Committee
2012-present, Institute for Translational Medicine and Therapeutics (ITMAT) at the Perelman School of Medicine, UPenn

Leadership and Memberships

Memberships in Professional Organizations

2018-present, Association for Academic Surgery

2017-present, American Society of Gene and Cell Therapy

2015-present, International Fetal Transplantation and Immunology Society (iFeTIS)

 - 2017-present, Treasurer

2015-present, American Pediatric Surgical Association

2014-present, American Pediatric Surgical Association

2008-present, American College of Surgeons