Natalie Rintoul, MD, is a Professor of Clinical Pediatrics at the University of Pennsylvania School of Medicine and attending neonatologist at Children's Hospital of Philadelphia.
After receiving her medical degree at Queen's University in Canada, Dr. Rintoul completed her pediatric residency at Massachusetts General Hospital in Boston and her neonatal fellowship at The Children's Hospital of Philadelphia.
Dr. Rintoul is not only interested in the care of the neonate with congenital anomalies requiring neonatal surgery, but also those neonates requiring heart-lung bypass (ECMO). She is co-director of the Neonatal Surgical Team, and medical director of the Neonatal ECMO Program. She is also a fetal consultant for the Richard D. Wood Jr. Center for Fetal Diagnosis and Treatment (CFDT).
Dr. Rintoul’s research interests include management of myelomeningocele, pulmonary hypoplasia and pulmonary hypertension in congenital diaphragmatic hernia, and perioperative care of the surgical neonate. She is the chair of the Neonatal Perioperative Committee. Dr. Rintoul is also a key member of the Special Delivery Unit, involved in the creation and implementation of delivery room guidelines for infants with congenital anomalies.
MD - Queen's University School of Medicine, Kingston, Ontario, Canada
Pediatrics - Massachusetts General Hospital, Harvard University, Boston, MA
Neonatal-Perinatal Medicine - The Children's Hospital of Philadelphia, Philadelphia, PA
Neonatal-Perinatal Medicine – American Board of PediatricsPediatrics – American Board of Pediatrics
Attending Neonatologist
Co-director, Neonatal Surgical Team
Medical Director, Neonatal Surgical Service
Medical Director, Neonatal Extracorporeal Membrane Oxygenation (ECMO)
Professor of Clinical Pediatrics, Perelman School of Medicine at the University of Pennsylvania
Myelomeningocele
Pulmonary hypertension
Pulmonary hypoplasia
Perioperative care of the surgical neonate
ECMO
Neonatal resuscitation
Nelson O, Rintoul NE, Tan JM, Simpao AF, Chuo J, Hedrick HL, Duran MS, Makeneni S, Devine M, Cao L, Stricker PA. Surgical neonates: A retrospective review of procedures and postoperative outcomes at a quaternary children's hospital. Paediatr Anaesth. 2023 Dec 25. doi: 10.1111/pan.14827. Epub ahead of print. PMID: 38146211.
Danzer E, Schreiber JE, Hoffman C, Mathew L, Flohr SJ, Eppley E, Land SD, Herkert L, Rintoul NE, Adzick NS, Hedrick HL. Prevalence and patterns of executive function, adaptive function, and behavioral outcomes in preschool and school age children with congenital diaphragmatic hernia. Early Hum Dev. 2023 Dec 9;188:105914. doi: 10.1016/j.earlhumdev.2023.105914. Epub ahead of print. PMID: 38103310.
Goldshore M, Land S, Flohr S, Mathew L, Reynolds T, Eppley E, Rintoul N, Gebb J, Howell L, Adzick NS, Hedrick H. The Impact of Comprehensive Fetal Care on Mortality of Children With Congenital Diaphragmatic Hernia when Delivery is Co-located in a Pediatric Hospital. J Pediatr Surg. 2023 Sep 27:S0022-3468(23)00577-8. doi: 10.1016/j.jpedsurg.2023.09.039. Epub ahead of print. PMID: 37914590.
Bose SK, Stratigis JD, Ahn N, Pogoriler J, Hedrick HL, Rintoul NE, Partridge EA, Flake AW, Khalek N, Gebb J, Teefey CP, Soni S, Hamaguchi R, Moldenhauer J, Adzick NS, Peranteau WH. Prenatally Diagnosed Large Lung Lesions: Timing of Resection and Perinatal Outcomes. J Pediatr Surg. 2023 Dec;58(12):2384-2390. doi: 10.1016/j.jpedsurg.2023.09.002. Epub 2023 Sep 9. PMID: 37813715.
Johng S, Licht DJ, Hedrick HL, Rintoul N, Linn RL, Gebb JS, Xiao R, Massey SL. Prenatal Brain Maturation is Delayed in Neonates with Congenital Diaphragmatic Hernia. J Pediatr. 2024 Jan;264:113738. doi: 10.1016/j.jpeds.2023.113738. Epub 2023 Sep 16. PMID: 37722557.
Orlinsky R, Land S, Flohr S, Rintoul N, Goldshore M, Hedrick HL. Birth Admission Length-of-Stay and Hospital Readmission in Children With Congenital Diaphragmatic Hernia. J Pediatr Surg. 2023 Dec;58(12):2368-2374. doi: 10.1016/j.jpedsurg.2023.08.002. Epub 2023 Aug 9. PMID: 37659921.
Linden AF, Howk AA, Billimoria Z, Devine M, DiGeronimo R, Gray B, Hamrick SE, Keene SD, Rintoul N, Mahmood B; Children's Hospitals Neonatal Consortium (CHNC). Neonatal Carotid Artery and Internal Jugular Vein Management Practices at Extracorporeal Membrane Oxygenation Decannulation: No Standard Approach. J Pediatr Surg. 2023 Nov;58(11):2196-2200. doi: 10.1016/j.jpedsurg.2023.07.007. Epub 2023 Jul 24. PMID: 37573253.
Bapat R, Duran M, Piazza A, Pallotto EK, Joe P, Chuo J, Mingrone T, Hawes J, Powell M, Falciglia GH, Grover TR, Rintoul N, MacPherson MJ, Rose A, Brozanski B. A Multicenter Collaborative to Improve Postoperative Pain Management in the NICU. Pediatrics. 2023 Aug 1;152(2):e2022059860. doi: 10.1542/peds.2022-059860. PMID: 37409386.
Avitabile CM, Flohr S, Mathew L, Wang Y, Ash D, Frank DB, Tingo JE, Rintoul NE, Hedrick HL. Quantitative Measures of Right Ventricular Size and Function by Echocardiogram Correlate with Cardiac Catheterization Hemodynamics in Congenital Diaphragmatic Hernia. J Pediatr. 2023 Oct;261:113564. doi: 10.1016/j.jpeds.2023.113564. Epub 2023 Jun 15. PMID: 37329980.
Danzer E, Massey SL, Flohr SJ, Mathew L, Hoffman C, Abramson A, Selenski P, Canning CE, Eppley E, Connelly JT, Herkert L, Rintoul NE, Adzick NS, Abend NS, Hedrick HL. Extracorporeal Membrane Oxygenation for Neonates With Congenital Diaphragmatic Hernia: Prevalence of Seizures and Outcomes. Pediatr Crit Care Med. 2023 May 1;24(5):e224-e235. doi: 10.1097/PCC.0000000000003197. Epub 2023 Feb 22. PMID: 37140337; PMCID: PMC10160669.
De Bie FR, Avitabile CM, Flohr S, Land S, Mathew L, Wang Y, Ash D, Rintoul NE, Hedrick HL. Treprostinil in Neonates with Congenital Diaphragmatic Hernia-Related Pulmonary Hypertension. J Pediatr. 2023 Aug;259:113420. doi: 10.1016/j.jpeds.2023.113420. Epub 2023 Apr 12. PMID: 37059388.
Mahmood B, Murthy K, Rintoul N, Weems M, Keene S, Brozanski B, DiGeronimo R, Haberman B, Hedrick H, Gien J, Seabrook R, Ali N, Chapman R, Daniel J, Harrison A, Johnson Y, Porta NFM, Uhing M, Zaniletti I, Grover TR; Children's Hospitals Neonatal Consortium: Predicting treatment of pulmonary hypertension at discharge in infants with congenital diaphragmatic hernia. J Perinatol January 2022.
Wild KT, Schindewolf E, Hedrick HL, Rintoul NE, Hartman T, Gebb J, Moldenhauer JS, Zackai EH, Krantz ID: The Genomics of Congenital Diaphragmatic Hernia: A 10-Year Retrospective Review. J Pediatr S0022-3476(22): 00326-2, April 2022 Notes: doi: 10.1016/j.jpeds.2022.04.012. Epub ahead of print.
Wild KT, Mathew L, Hedrick HL, Rintoul NE, Ades A, Soorikian L, Matthews K, Posencheg MA, Kesler E, Van Hoose KT, Panitch HB, Flibotte J, Foglia EE. Respiratory function after birth in infants with congenital diaphragmatic hernia. hernia. Arch Dis Child Fetal Neonatal Ed. 2022 Nov 18:fetalneonatal-2022-324415. doi: 10.1136/archdischild-2022-324415. Epub ahead of print. PMID: 36400455.
Pawlowski TW, Stoller JZ, Rintoul NE, Hedrick HL, Quartermain MD, Fraga MV: Point-of-care Ultrasound for the Evaluation of Venous Cannula Position in Neonatal Extracorporeal Membrane Oxygenation. Journal of Perinatology 41(7): 1645-1650, 2021.
Seabrook RB, Grover TR, Rintoul N, Weems M, Keene S, Brozanski B, DiGeronimo R, Haberman B, Hedrick H, Gien J, Ali N, Chapman R, Daniel J, Harrison HA, Johnson Y, Porta NFM, Uhing M, Zaniletti I, Murthy K; Children’s Hospitals Neonatal Consortium Congenital Diaphragmatic Hernia Focus Group. Treatment of pulmonary hypertension during initial hospitalization in a multicenter cohort of infants with congenital diaphragmatic hernia (CDH). J Perinatol. 2021 Mar 1. doi: 10.1038/s41372-021-00923-z. Online ahead of print. PMID: 33649432
Grover TR, Weems MF, Brozanski B, Daniel J, Haberman B, Rintoul N, Walden A, Hedrick H, Mahmood B, Seabrook R, Murthy K, Zaniletti I, Keene S; Children's Hospitals Neonatal Consortium (CHNC) Congenital Diaphragmatic Hernia Focus Group. Central Line Utilization and Complications in Infants with Congenital Diaphragmatic Hernia. Am J Perinatol. 2021 Feb 3. doi: 10.1055/s-0041-1722941. Online ahead of print. PMID: 33535242
Lin EE, Nelson O, Isserman RS, Henderson AA, Rintoul NE, Lioy J, Javia LR, Tran KM, Fiadjoe JE. Management of neonatal difficult airway emergencies in the delivery room. Paediatr Anaesth. 2020 May;30(5):544-551. doi: 10.1111/pan.13859. Epub 2020 Apr 22.PMID: 32196824
Chotzoglou E, Hedrick HL, Herkert LM, Goldshore MA, Rintoul NE, Panitch HB. Therapy at 30 days of life predicts lung function at 6 to 12 months in infants with congenital diaphragmatic hernia. Pediatr Pulmonol. 2020 Jun;55(6):1456-1467. doi: 10.1002/ppul.24736. Epub 2020 Mar 19.PMID: 3219139
Riley JS, Antiel RM, Flake AW, Johnson MP, Rintoul NE, Lantos JD, Traynor MD, Adzick NS, Feudtner C, Heuer GG. Pediatric neurosurgeons' views regarding prenatal surgery for myelomeningocele and the management of hydrocephalus: a national survey. Neurosurg Focus. 2019 Oct 1;47(4):E8. doi: 10.3171/2019.7.FOCUS19406.PMID: 31574481
Foglia EE, Ades A, Hedrick HL, Rintoul N, Munson DA, Moldenhauer J, Gebb J, Serletti B, Chaudhary A, Weinberg DD, Napolitano N, Fraga MV, Ratcliffe SJ. Initiating resuscitation before umbilical cord clamping in infants with congenital diaphragmatic hernia: a pilot feasibility trial. Arch Dis Child Fetal Neonatal Ed. 2020 May;105(3):322-326. doi: 10.1136/archdischild-2019-317477. Epub 2019 Aug 28.PMID: 31462406 Clinical Trial.
Franciscovich CD, Monk HM, Brodecki D, Rogers R, Rintoul NE, Hedrick HL, Ely E. Sedation Practices of Neonates Receiving Extracorporeal Membrane Oxygenation. ASAIO J. 2020 May;66(5):559-564. doi: 10.1097/MAT.0000000000001043.PMID: 31425254
Rintoul NE, Keller RL, Walsh WF, Burrows PK, Thom EA, Kallan MJ, Howell LJ, Adzick NS, MOMS Investigators. The Management of Myelomeningocele Study: Short-Term Neonatal Outcomes. Fetal Diagn Ther. 2020 Aug 31;1-8. doi: 10.1159/000509245. PMID: 32866951
Brozanski BS, Piazza AJ, Chuo J, Natarajan G, Grover TR, Smith JR, Mingrone T, McClead RE, Rakesh R, Rintoul N, Guidash J, Bellflower B, Holston M, Richardson T, Pallotto EK. STEPP IN: Working Together to Keep Infants Warm in the Perioperative Period. Pediatrics. 2020 Apr;145(4):e20191121. doi: 10.1542/peds.2019-1121.Epub 2020 Mar 19. Read the abstract.
Wild KT, Rintoul N, Kattan J, Gray B, Engle RW, Keene S, Best D, Davis C, DiGeronimo R, Raman L. Extracorporeal Life Support Organization (ELSO): Guidelines for Neonatal Respiratory Failure. ASAIO Journal: May 2020 - Volume 66 - Issue 5 - p 463-470. Read the abstract.
Keene S, Grover TR, Murthy K, Pallotto EK, Brozanski B, Gien J, Zaniletti I, Johnson YR, Seabrook RB, Porta NFM, Haberman B, DiGeronimo R, Rintoul N; Children’s Hospitals Neonatal Consortium’s (CHNC) Congenital Diaphragmatic Hernia Focus Group. Extracorporeal membrane oxygenation and bloodstream infection in congenital diaphragmatic hernia. J Perinatol. 2019 Oct;39(10):1384-1391. doi: 10.1038/s41372-019-0435-5. Epub 2019 Aug 5.PMID: 31383944
Fraga MV, Dysart KC, Rintoul N, Chaudhary AS, Ratcliffe SJ, Fedec A, Kren S, Cohen MS, Kirpalani H. Cardiac Output Measurement Using the Ultrasonic Cardiac Output Monitor: A Validation Study in Newborn Infants. Neonatology. 2019;116(3):260-268. doi: 10.1159/000501005. Epub 2019 Jul 19.PMID: 31326967
Danzer E, Hoffman C, Miller JS, D'Agostino JA, Schindewolf EM, Gerdes M, Bernbaum J, Adams SE, Rintoul NE, Herkert LM, Taylor L, Schreiber J, Peranteau WH, Flake AW, Adzick NS, Hedrick HL. Autism spectrum disorder and neurodevelopmental delays in children with giant omphalocele. J Pediatr Surg. 2019 Sep;54(9):1771-1777. doi: 10.1016/j.jpedsurg.2019.05.017. Epub 2019 May 28.PMID: 3119666
Lawrence KM, Berger K, Herkert L, Franciscovich C, O'Dea CLH, Waqar LN, Partridge E, Hanna BD, Peranteau WH, Avitabile CM, Hopper RK, Rintoul NE, Hedrick HL. Use of prostaglandin E1 to treat pulmonary hypertension in congenital diaphragmatic hernia. J Pediatr Surg. 2019 Jan;54(1):55-59. doi: 10.1016/j.jpedsurg.2018.10.039. Epub 2018 Oct 5.PMID: 30442461
Murthy K, Porta NFM, Pallotto EK, Rintoul N, Keene S, Chicoine L, Gien J, Brozanski BS, Johnson YR, Haberman B, DiGeronimo R, Zaniletti I, Grover TR; Children's Hospitals Neonatal Consortium (CHNC) Congenital Diaphragmatic Hernia Focus Group. Predicting Risk of Infection in Infants with Congenital Diaphragmatic Hernia. J Pediatr. 2018 Dec;203:101-107.e2. doi: 10.1016/j.jpeds.2018.07.032. Epub 2018 Sep 11.PMID: 30217691
Riley JS, Antiel RM, Rintoul NE, Ades AM, Waqar LN, Lin N, Herkert LM, D'Agostino JA, Hoffman C, Peranteau WH, Flake AW, Adzick NS, Hedrick HL. Reduced oxygen concentration for the resuscitation of infants with congenital diaphragmatic hernia. J Perinatol. 2018 Jul;38(7):834-843. doi: 10.1038/s41372-017-0031-5. Epub 2018 Jun 11.PMID: 29887609
Lawrence KM, Hedrick HL, Monk HM, Herkert L, Waqar LN, Hanna BD, Peranteau WH, Rintoul NE, Hopper RK. Treprostinil Improves Persistent Pulmonary Hypertension Associated with Congenital Diaphragmatic Hernia. J Pediatr. 2018 Sep;200:44-49. doi: 10.1016/j.jpeds.2018.04.052. Epub 2018 May 18.PMID: 29784517
Danzer E, Hoffman C, D'Agostino JA, Boelig MM, Gerdes M, Bernbaum JC, Rosenthal H, Waqar LN, Rintoul NE, Herkert LM, Kallan MJ, Peranteau WH, Flake AW, Adzick NS, Hedrick HL. Short-Term Neurodevelopmental Outcome in Children Born With High-Risk Congenital Lung Lesions. Ann Thorac Surg. 2018 Jun;105(6):1827-1834. doi: 10.1016/j.athoracsur.2018.01.033. Epub 2018 Feb 10.PMID: 29438655
Danzer E, Hoffman C, D'Agostino JA, Miller JS, Waqar LN, Gerdes M, Bernbaum JC, Rosenthal H, Rintoul NE, Herkert LM, Peranteau WH, Flake AW, Adzick NS, Hedrick HL. Rate and Risk Factors Associated with Autism Spectrum Disorder in Congenital Diaphragmatic Hernia. J Autism Dev Disord. 2018 Jun;48(6):2112-2121. doi: 10.1007/s10803-018-3472-6.PMID: 29383650
Grover TR, Rintoul NE, Hedrick HL. Extracorporeal membrane oxygenation in infants with congenital diaphragmatic hernia. Semin Perinatol. 2018 Mar;42(2):96-103. doi: 10.1053/j.semperi.2017.12.005. Epub 2018 Jan 12.PMID: 29338874 Review.
Kamdar A, Rintoul N, Raffini L. Anticoagulation in neonatal ECMO. Semin Perinatol. 2018 Mar;42(2):122-128. doi: 10.1053/j.semperi.2017.12.008. Epub 2018 Jan 12.PMID: 29336832 Review.
Danzer E, Hoffman C, D'Agostino JA, Connelly JT, Waqar LN, Gerdes M, Bernbaum J, Rintoul NE, Herkert LM, Peranteau WH, Flake AW, Adzick NS, Hedrick HL. Short-Term Neurodevelopmental Outcome in Congenital Diaphragmatic Hernia: The Impact of Extracorporeal Membrane Oxygenation and Timing of Repair. Pediatr Crit Care Med. 2018 Jan;19(1):64-74. doi: 10.1097/PCC.0000000000001406.PMID: 29303891
Johnston LC, Rintoul NE, Ades AM. Introduction: Update on neonatal extracorporeal membrane oxygenation. Semin Perinatol. 2018 Mar;42(2):65-67. doi: 10.1053/j.semperi.2017.12.001. Epub 2017 Dec 29.PMID: 29291939 No abstract available.
Keene S, Murthy K, Pallotto E, Brozanski B, Gien J, Zaniletti I, Hulbert C, Seabrook R, Rintoul N, Chicoine L, Porta N, Grover TR. Acquired Infection and Antimicrobial Utilization During Initial NICU Hospitalization in Infants With Congenital Diaphragmatic Hernia. Pediatr Infect Dis J. 2018 May;37(5):469-474. doi: 10.1097/INF.0000000000001835.PMID: 29189614
Antiel RM, Flake AW, Collura CA, Johnson MP, Rintoul NE, Lantos JD, Curlin FA, Tilburt JC, Brown SD, Feudtner C. Weighing the Social and Ethical Considerations of Maternal-Fetal Surgery. Pediatrics. 2017 Dec;140(6):e20170608. doi: 10.1542/peds.2017-0608. Epub 2017 Nov 3.PMID: 29101225 Free article.
Antiel RM, Lin N, Licht DJ, Hoffman C, Waqar L, Xiao R, Monos S, D'Agostino JA, Bernbaum J, Herkert LM, Rintoul NE, Peranteau WH, Flake AW, Adzick NS, Hedrick HL. Growth trajectory and neurodevelopmental outcome in infants with congenital diaphragmatic hernia. J Pediatr Surg. 2017 Dec;52(12):1944-1948. doi: 10.1016/j.jpedsurg.2017.08.063. Epub 2017 Sep 28.PMID: 29079316
Antiel RM, Curlin FA, Lantos JD, Collura CA, Flake AW, Johnson MP, Rintoul NE, Brown SD, Feudtner C. Attitudes of paediatric and obstetric specialists towards prenatal surgery for lethal and non-lethal conditions. J Med Ethics. 2018 Apr;44(4):234-238. doi: 10.1136/medethics-2017-104377. Epub 2017 Oct 10.PMID: 29018178
Antiel RM, Collura CA, Flake AW, Johnson MP, Rintoul NE, Lantos JD, Curlin FA, Tilburt JC, Brown SD, Feudtner C. Physician views regarding the benefits and burdens of prenatal surgery for myelomeningocele. J Perinatol. 2017 Sep;37(9):994-998. doi: 10.1038/jp.2017.75. Epub 2017 Jun 15.PMID: 28617430
Antiel RM, Flake AW, Johnson MP, Khalek N, Rintoul NE, Lantos JD, Curlin FA, Tilburt JC, Feudtner C. Specialty-Based Variation in Applying Maternal-Fetal Surgery Trial Evidence. Fetal Diagn Ther. 2017;42(3):210-217. doi: 10.1159/000455024. Epub 2017 Mar 17.PMID: 28301843
Gien J, Murthy K, Pallotto EK, Brozanski B, Chicoine L, Zaniletti I, Seabrook R, Keene S, Alapati D, Porta N, Rintoul N, Grover TR; Children's Hospitals Neonatal Consortium CDH Study Group. Short-term weight gain velocity in infants with congenital diaphragmatic hernia (CDH). Early Hum Dev. 2017 Mar-Apr;106-107:7-12. doi: 10.1016/j.earlhumdev.2017.01.010. Epub 2017 Feb 6.PMID: 28178582
Lin JJ, Banwell BL, Berg RA, Dlugos DJ, Ichord RN, Kilbaugh TJ, Kirsch RE, Kirschen MP, Licht DJ, Massey SL, Naim MY, Rintoul NE, Topjian AA, Abend NS. Electrographic Seizures in Children and Neonates Undergoing Extracorporeal Membrane Oxygenation. Pediatr Crit Care Med. 2017 Mar;18(3):249-257. doi: 10.1097/PCC.0000000000001067.PMID: 28099234 Free PMC article.
Antiel RM, Riley JS, Cahill PJ, Campbell RM, Waqar L, Herkert LM, Rintoul NE, Peranteau WH, Flake AW, Adzick NS, Hedrick HL. Management and outcomes of scoliosis in children with congenital diaphragmatic hernia. J Pediatr Surg. 2016 Dec;51(12):1921-1925. doi: 10.1016/j.jpedsurg.2016.09.013. Epub 2016 Sep 15.PMID: 28029369
Bamat NA, Tharakan SJ, Connelly JT, Hedrick HL, Lorch SA, Rintoul NE, Williams SB, Dysart KC. Venoarterial Extracorporeal Life Support for Neonatal Respiratory Failure: Indications and Impact on Mortality. ASAIO J. 2017 Jul/Aug;63(4):490-495. doi: 10.1097/MAT.0000000000000495.PMID: 27984316 Free PMC article.
Danzer E, Hoffman C, D’Agostino JA, Gerdes M, Bernbaum J, Antiel RM, Rintoul NE, Herkert LM, Flake AW, Adzick NS, Hedrick HL. Neurodevelopmental outcomes at 5 years of age in congenital diaphragmatic hernia. J Pediatr Surg. 2017 Mar;52(3):437-443.
Danzer E, Hoffman C, D'Agostino JA, Gerdes M, Bernbaum J, Antiel RM, Rintoul NE, Herkert LM, Flake AW, Adzick NS, Hedrick HL. Neurodevelopmental outcomes at 5years of age in congenital diaphragmatic hernia. J Pediatr Surg. 2017 Mar;52(3):437-443. doi: 10.1016/j.jpedsurg.2016.08.008. Epub 2016 Aug 30.PMID: 27622588
Partridge EA, Peranteau WH, Herkert L, Rendon N, Smith H, Rintoul NE, Flake AW, Adzick NS, Hedrick HL. Right- versus left-sided congenital diaphragmatic hernia: a comparative outcomes analysis. J Pediatr Surg. 2016 Jun;51(6):900-2. doi: 10.1016/j.jpedsurg.2016.02.049. Epub 2016 Mar 3.PMID: 27342009
Partridge EA, Peranteau WH, Herkert L, Rintoul NE, Flake AW, Adzick NS, Hedrick HL. Rate of increase of lung-to-head ratio over the course of gestation is predictive of survival in left-sided congenital diaphragmatic hernia. J Pediatr Surg. 2016 May;51(5):703-5. doi: 10.1016/j.jpedsurg.2016.02.006. Epub 2016 Feb 11.PMID: 27261559
Murthy K, Pallotto EK, Gien J, Brozanski BS, Porta NF, Zaniletti I, Keene S, Chicoine LG, Rintoul NE, Dykes FD, Asselin JM, Short BL, Padula MA, Durand DJ, Reber KM, Evans JR, Grover TR. Predicting death or extended length of stay in infants with congenital diaphragmatic hernia. J Perinatol. 2016 Aug;36(8):654-9. doi: 10.1038/jp.2016.26. Epub 2016 Mar 10.PMID: 26963428
Danzer E, Gerdes M, D’Agostino JA, Bernbaum J, Hoffman C, Herkert LM, Rintoul NE, Peranteau WH, Flake AW, Adzick NS, Hedrick HL. Younger gestational age is associated with increased risk of adverse neurodevelopmental outcome during infancy in congenital diaphragmatic hernia. J Pediatr Surg. 2016 Jul;51(7):1084-90.
Peranteau WH, Boelig MM, Khalek N, Moldenhauer JS, Martinez-Poyer J, Hedrick HL, Flake AW, Johnson MP, Adzick NS. Effect of single and multiple courses of maternal betamethasone on prenatal congenital lung lesion growth and fetal survival. J Pediatr Surg. 2016 Jan;51(1):28-32.
Sulkowski JP, Cooper JN, Pearson EG, Connelly JT, Rintoul N, Kilbaugh TJ, Deans KJ, Minneci PC. Hemolysis-Associated Nitric Oxide Dysregulation during Extracorporeal Membrane Oxygenation. J Extra Corpor Technol. 2014 Sep;46(3):217-23.PMID: 26357787 Free PMC article.
Grover TR, Murthy K, Brozanski B, Gien J, Rintoul N, Keene S, Najaf T, Chicoine L, Porta N, Zaniletti I, Pallotto EK; Children's Hospitals Neonatal Consortium. Short-term outcomes and medical and surgical interventions in infants with congenital diaphragmatic hernia. Am J Perinatol. 2015 Sep;32(11):1038-44. doi: 10.1055/s-0035-1548729. Epub 2015 Mar 31.PMID: 25825963
Danzer E, Gerdes M, D'Agostino JA, Bernbaum J, Hoffman C, Herkert L, Rintoul NE, Peranteau WH, Flake AW, Adzick NS, Hedrick HL. Neurodevelopmental outcome at one year of age in congenital diaphragmatic hernia infants not treated with extracorporeal membrane oxygenation. J Pediatr Surg. 2015 Jun;50(6):898-903. doi: 10.1016/j.jpedsurg.2015.03.040. Epub 2015 Mar 19.PMID: 25818204
Panitch HB, Weiner DJ, Feng R, Perez MR, Healy F, McDonough JM, Rintoul N, Hedrick HL. Lung function over the first 3 years of life in children with congenital diaphragmatic hernia. Pediatr Pulmonol. 2015 Sep;50(9):896-907.
Moldenhauer JS, Soni S, Rintoul NE, Spinner SS, Khalek N, Martinez-Poyer J, Flake AW, Hedrick HL, Peranteau WH, Rendon N, Koh J, Howell LJ, Heuer GG, Sutton LN, Johnson MP, Adzick NS. Fetal Myelomeningocele Repair: The Post-MOMS Experience at the Children's Hospital of Philadelphia. Fetal Diagn Ther. 2015;37(3):235-40. Epub 2014 Aug 15.
Partridge EA, Peranteau WH, Rintoul NE, Herkert LM, Flake AW, Adzick NS, Hedrick HL. Timing of repair of congenital diaphragmatic hernia in patients supported by extracorporeal membrane oxygenation (ECMO). J Pediatr Surg. 2015 Feb;50(2):260-2.
Partridge EA, Hanna BD, Rintoul NE, Herkert L, Flake AW, Adzick NS, Hedrick HL, Peranteau WH. Brain-type natriuretic peptide levels correlate with pulmonary hypertension and requirement for extracorporeal membrane oxygenation in congenital diaphragmatic hernia. J Pediatr Surg. 2015 Feb;50(2):263-6.
Danzer E, Gerdes M, D'Agostino JA, Bernbaum J, Hoffman C, Rintoul NE, Herkert LM, Flake AW, Adzick NS, Hedrick HL. Patient characteristics are important determinants of neurodevelopmental outcome during infancy in giant omphalocele. Early Hum Dev. 2015 Feb 9;91(3):187-193.
Peranteau WH, Tharakan SJ, Partridge E, Herkert L, Rintoul NE, Flake AW, Adzick NS, Hedrick HL. Systemic hypertension in giant omphalocele: An underappreciated association. J Pediatr Surg. 2015 Feb 23. pii: S0022-3468(15)00131-1. doi: 10.1016.
Partridge EA, Hanna BD, Panitch HB, Rintoul NE, Peranteau WH, Flake AW, Scott Adzick N, Hedrick HL. Pulmonary hypertension in giant omphalocele infants. J Pediatr Surg. 2014 Dec;49(12):1767-70. doi: 10.1016/j.jpedsurg.2014.09.016. Epub 2014 Nov 14.PMID: 25487480
McIntyre CM, Hanna BD, Rintoul N, Ramsey EZ. Safety of epoprostenol and treprostinil in children less than 12 months of age. Pulm Circ. 2013 Dec;3(4):862-9. doi: 10.1086/674762.PMID: 25006402 Free PMC article.
Partridge EA, Bridge C, Donaher JG, Herkert LM, Grill E, Danzer E, Gerdes M, Hoffman CH, D'Agostino JA, Bernbaum JC, Rintoul NE, Peranteau WH, Flake AW, Adzick NS, Hedrick HL. Incidence and factors associated with sensorineural and conductive hearing loss among survivors of congenital diaphragmatic hernia. J Pediatr Surg. 2014 Jun;49(6):890-4; discussion 894. doi: 10.1016/j.jpedsurg.2014.01.019. Epub 2014 Jan 31.PMID: 24888829
Danzer E, Gerdes M, D'Agostino JA, Hoffman C, Bernbaum J, Bebbington MW, Siegle J, Sulkowski J, Rintoul NE, Flake AW, Scott Adzick N, Hedrick HL.J Perinatol. Longitudinal neurodevelopmental and neuromotor outcome in congenital diaphragmatic hernia patients in the first 3 years of life. 2013 Nov;33(11):893-8. doi: 10.1038/jp.2013.47. Epub 2013 May 9.PMID: 23660581
Danzer E, Gerdes M, D'Agostino JA, Partridge EA, Hoffman-Craven CH, Bernbaum J, Rintoul NE, Flake AW, Adzick NS, Hedrick HL. Preschool neurological assessment in congenital diaphragmatic hernia survivors: outcome and perinatal factors associated with neurodevelopmental impairment. Early Hum Dev. 2013 Jun;89(6):393-400. doi: 10.1016/j.earlhumdev.2012.12.009. Epub 2013 Jan 17.PMID: 23333410
Danzer E, Hedrick HL, Rintoul NE, Siegle J, Adzick NS, Panitch HB. Assessment of early pulmonary function abnormalities in giant omphalocele survivors. J Pediatr Surg. 2012 Oct;47(10):1811-20. doi: 10.1016/j.jpedsurg.2012.06.006.PMID: 23084189
Danzer E, Victoria T, Bebbington MW, Siegle J, Rintoul NE, Johnson MP, Flake AW, Adzick NS, Hedrick HL. Fetal MRI-calculated total lung volumes in the prediction of short-term outcome in giant omphalocele: preliminary findings. Fetal Diagn Ther. 2012;31(4):248-53. doi: 10.1159/000334284. Epub 2012 Apr 27.PMID: 22572017 Review.
Danzer E, Siegle J, D'Agostino JA, Gerdes M, Hoffman C, Bernbaum J, Rintoul NE, Flake AW, Adzick NS, Hedrick HL. Early neurodevelopmental outcome of infants with high-risk fetal lung lesions. Fetal Diagn Ther. 2012;31(4):210-5. doi: 10.1159/000336228. Epub 2012 Apr 26.PMID: 22539010 Free article.
Cahill AM, Nijs E, Ballah D, Rabinowitz D, Thompson L, Rintoul N, Hedrick H, Jacobs I, Low D. Percutaneous sclerotherapy in neonatal and infant head and neck lymphatic malformations: a single center experience. J Pediatr Surg. 2011 Nov;46(11):2083-95. doi: 10.1016/j.jpedsurg.2011.07.004.PMID: 22075337
Wedlich KV, Rintoul N, Peacock S, Cape JN, Coyle M, Toet S, Barnes J, Ashmore M. Effects of ozone on species composition in an upland grassland. Oecologia. 2012 Apr;168(4):1137-46. doi: 10.1007/s00442-011-2154-2. Epub 2011 Nov 3.PMID: 22048840
Adzick NS, Thom EA, Spong CY, Brock JW 3rd, Burrows PK, Johnson MP, Howell LJ, Farrell JA, Dabrowiak ME, Sutton LN, Gupta N, Tulipan NB, D'Alton ME, Farmer DL; MOMS Investigators. A randomized trial of prenatal versus postnatal repair of myelomeningocele. N Engl J Med. 2011 Mar 17;364(11):993-1004. doi: 10.1056/NEJMoa1014379. Epub 2011 Feb 9.PMID: 21306277 Free PMC article. Clinical Trial.
Danzer E, Finkel R, Gerdes M, Schwartz EM, Rintoul NN, Adzick NS, Johnson MP. The relationship of seizure activity and chronic epilepsy in early infancy and short-term neurodevelopmental outcome following fetal myelomeningocele closure. Neuropediatrics. 2010 Jun;41(3):140-3. doi: 10.1055/s-0030-1263164. Epub 2010 Sep 21.PMID: 20859834
Danzer E, Gerdes M, Bernbaum J, D'Agostino J, Bebbington MW, Siegle J, Hoffman C, Rintoul NE, Flake AW, Adzick NS, Hedrick HL. Neurodevelopmental outcome of infants with congenital diaphragmatic hernia prospectively enrolled in an interdisciplinary follow-up program. J Pediatr Surg. 2010 Sep;45(9):1759-66. doi: 10.1016/j.jpedsurg.2010.03.011.PMID: 20850617
Danzer E, Gerdes M, D'Agostino JA, Bernbaum J, Siegle J, Hoffman C, Rintoul NE, Liechty KW, Flake AW, Adzick NS, Hedrick HL. Prospective, interdisciplinary follow-up of children with prenatally diagnosed giant omphalocele: short-term neurodevelopmental outcome. J Pediatr Surg. 2010 Apr;45(4):718-23. doi: 10.1016/j.jpedsurg.2009.09.004.PMID: 20385277
Danzer E, Finkel RS, Rintoul NE, Bebbington MW, Schwartz ES, Zarnow DM, Adzick NS, Johnson MP. Reversal of hindbrain herniation after maternal-fetal surgery for myelomeningocele subsequently impacts on brain stem function. Neuropediatrics. 2008 Dec;39(6):359-62. doi: 10.1055/s-0029-1202835. Epub 2009 Jun 30.PMID: 19569004
Danzer E, Ernst LM, Rintoul NE, Johnson MP, Adzick NS, Flake AW. In utero meconium passage in fetuses and newborns with myelomeningocele. J Neurosurg Pediatr. 2009 Feb;3(2):141-6. doi: 10.3171/2008.10.PEDS08199.PMID: 19278315
Danzer E, Adzick NS, Rintoul NE, Zarnow DM, Schwartz ES, Melchionni J, Ernst LM, Flake AW, Sutton LN, Johnson MP. Intradural inclusion cysts following in utero closure of myelomeningocele: clinical implications and follow-up findings. J Neurosurg Pediatr. 2008 Dec;2(6):406-13. doi: 10.3171/PED.2008.2.12.406.PMID: 19035686
Johnson MP, Gerdes M, Rintoul N, Pasquariello P, Melchionni J, Sutton LN, Adzick NS. Maternal-fetal surgery for myelomeningocele: neurodevelopmental outcomes at 2 years of age. Am J Obstet Gynecol. 2006 Apr;194(4):1145-50; discussion 1150-2. doi: 10.1016/j.ajog.2006.01.072.PMID: 16580316
Bouchard S, Davey MG, Rintoul NE, Walsh DS, Rorke LB, Adzick NS. Correction of hindbrain herniation and anatomy of the vermis after in utero repair of myelomeningocele in sheep. J Pediatr Surg. 2003 Mar;38(3):451-8; discussion 451-8. doi: 10.1053/jpsu.2003.50078.PMID: 12632366
Rintoul NE, Crombleholme TM. Prenatal diagnosis and treatment of intersex states. Adv Exp Med Biol. 2002;511:225-37; discussion 237-8. doi: 10.1007/978-1-4615-0621-8_13.PMID: 12575764 Review. No abstract available.
Rintoul NE, Sutton LN, Hubbard AM, Cohen B, Melchionni J, Pasquariello PS, Adzick NS. A new look at myelomeningoceles: functional level, vertebral level, shunting, and the implications for fetal intervention. Pediatrics. 2002 Mar;109(3):409-13. doi: 10.1542/peds.109.3.409.PMID: 11875133
Celee L, Lee L, Rintoul N, Savani RC, Long W, Mennutti MT, Krantz ID: Duplication of chromosome region 4q28.3-qter in monozygotic twins with discordant phenotypes. American Journal of Medical Genetics 94(2): 125-140, Sep 2000.
Jackson AC, Rintoul NE: Effects of post-mortem autolysis on the detection of rabies virus genomic RNA and mRNA in mouse brain using in situ hybridization. Mol Cell Probes 6(3): 231-235, June 1992.
Crombleholme TM, Lim FY, Piero JL, Simpson L, Rintoul NE: Fetal and Neonatal Surgery: Diagnosis and Management of the Fetal and Neonatal Patient. McGraw-Hill. Crombelholme TM, Lim FY, Piero JL, Simpson L, Rintoul NE (eds.). McGraw-Hill, Accepted 2020.
Fraga MV, Connelly J, Hedrick HL, Rintoul NE: Special considerations for neonatal ECMO. Imaging of the Newborn 2011.
Wild T, Chapman R, Davis C, Rintoul N, Westrope C, Short BS: Neonatal Respiratory Failure. 6th Edition of Extracorporeal Life Support: The ELSO Red Book 2022.
Wild KT, Rintoul NE, Pruder M, Hansen AR. . In , ed. : "Surgical Conditions of the Neonate" Cloherty and Stark's Manual of Neonatal Care. Eichenwald EC, Hansen AR, Martin CR, and Stark AR (eds.). Wolters Kluwer, 9th Edition, 2022 Notes: In press.
Wild KT, Chapman RL, Davis CF, Rintoul NE, Westrope CA, Short BL: "Initiating ECLS for Neonatal Respiratory Failure" Extracorporeal Life Support: The ELSO Red Book. MacLaren G, Brodie D, Lorusso R, Peek G, Thiagarajan R, and Vercaemst L (eds.). Extracorporeal Life Support Organization (ELSO), 6th Edition, 2022 Notes: In press.
Wild KT, Gray BW, Brunetti M, Connelly JT, Rintoul N: Extracorporeal Life Support: Neonatal Respiratory and Cardiac Disease In Tschaut RJ, ed., Extracorporeal Circulation in Theory and Practice, Lengerich, Germany. Pabst Science Publishers, .: 619-627, 2020 Notes: Chapter 15.
Wild KT, Gray B, Brunetti M, Connelly JT, Rintoul N: "Extracorporeal Life Support: Neonatal respiratory and cardiac disease" Extracorporeal Circulation in Theory and Practice. Tschaut RJ (eds.). Lengerich, Germany: Pabst Science Publishers, Page: 619-627, 2020.
Lord K, Duran M, Rintoul NE: Perioperative Management of Hyperinsulinism. Congenital Hyperinsulinism: A Practical Guide to Diagnosis and Management. De Leon-Crutchlow DD, Stanley CA (eds.). Springer, Page: 113-118, January 2019.
Rintoul NE, Ades A, Adzick NS: Fetal Therapy. Rudolph's Pediatrics (23rd Edition, Chapter 42). Kline, MW (eds.). McGraw-Hill Education, August 2018.
Danzer E, Rintoul NE, Crombleholme TM, Adzick NS: Pathophysiology of neural tube defects. In: Fetal and Neonatal Physiology, 5th Ed. Polin RA, Fox WW, Abman SH (eds.). WB Saunders, Philadelphia, PA, 2016.
Danzer E, Rintoul NE, Adzick NS: Pathophysiology of neural tube defects. Fetal and Neonatal Physiology, 4th Edition. Polin RA, Fox WW, Abman SH (eds.). WB Saunders, Philadelphia, PA, 2: pp 1848-1862, 2011.
Danzer E, Rintoul NE, Crombleholme TM, Adzick NS: Pathophysiology of Neural Tube Defects. Fetal and Neonatal Physiology, 3rd Edition. Polin RA, Fox WW, Abman SH (eds.). WB Saunders, Philadelphia, PA, 2: pp 1772-1785, 2004.
Rintoul N, Crombleholme T: Prenatal diagnosis and management of the intersex syndromes. In: Pediatric Gender Reassignment. Zderic SA, Canning DA, Carr MC, Snyder III HM (eds.). Springer Press, NY, 511: pp 225-238, 2002.
Gray B, Carr N, Chapman R, Chi A, Dariya V, Dirnberger D, Fernandes C, Hamrick S, Keene S, Linden A, Makkar A, Menkiti O, Miquel-Verges F, Quinones-Cardona V, Rao R, Rodriguez R, Seabrook R, Suttner D, Weems M, Rintoul N, DiGeronimo R, CHNC ECMO Focus Group: Early Use Experience of the Novel Crescent RA Neonatal VV-ECMO Cannula Among CHNC ECMO Focus Group Members. Neonatal ECMO Session, 38th Annual Children's National Symposium: ECMO & the Advanced Therapies for Cardiac and Respiratory Failure, Keystone, CO February 2022.
Wild KT, Miquel-Verges F, Rintoul NE, DiGeronimo R, Keene S, Hamrick SE, Chapman R, Sullivan K, Dirnberger D, Shenberger J, Mahmood B, Rao R, Seabrook RB, Makkar Abhishek, Daniel J, Billimoria Z, Carr N, CHNC ECMO Focus Group: Practice Variation in Perceived Optimal Genetic Testing Across CHNC ECMO Centers. Neonatal ECMO Session, 38th Annual Children's National Symposium: ECMO & the Advanced Therapies for Cardiac and Respiratory Failure, Keystone, CO February 2022.
Finnegan L, Ades A, Rintoul N, Srinivasan L: Early-Onset Sepsis and Antibiotic Exposure Among Infants With Congenital. Eastern Society for Pediatric Research (ESPR), Philadelphia, PA March 2022 Notes: Oral Presentation?
Johng S, Licht D, Hedrick H, Rintoul N, Linn R, Xiao R, Massey S: Prenatal Brain Maturation in Neonates With Congenital Diaphragmatic Hernia. Eastern Society for Pediatric Research (ESPR), Philadelphia, PA March 2022 Notes: Oral Presentation?
De Bie FR, Avitabile CM, Flohr S, Land S, Mathew L, Rintoul NE, Hedrick HL: "Brain natriuretic peptide levels in children with congenital diaphragmatic hernia-related pulmonary hypertension treated with treprostinil" International Congenital Diaphragmatic Hernia Symposium April 2022.
Pallotto E, Piazza AJ, Chuo J, Duran M, Grover T, Falciglia G, Hawes J, Mingrone T, Joe P, Rintoul N, Bartman T, McClead R, Rose AP, Naing K, MacPherson MJ, Brozanski B: STEPP IN (Safe Transitions & Euthermia in the Perioperative Period in Infants & Neonates) Next Steps: Quality Improvement Enhances Team Culture of Safety. Pediatric Academic Societies (PAS), Denver, CO April 2022 Notes: Poster Presentation.
Piazza A, Brozanski B, Duran M, Chuo J, Grover T, Falciglia G, Hawes J, Mingrone T, Joe P, Rintoul N, Bartman T, McClead R, MacPherson MJ, Rose AP, Pallotto E: STEPP IN Next Steps: Using Perioperative Handoff Communication to Optimize Patient Outcomes. Pediatric Academic Societies (PAS), Denver, CO April 2022 Notes: Oral Presentation.
Schwartz K, Rintoul N, Hedrick H: Outcomes and Surgical Decision-making for Neonates with Trisomy 13 (T13) or Trisomy 18 (T18) and Congenital Diaphragmatic Hernia (CDH): A Single Center Case Series. International Congenital Diaphragmatic Hernia Symposium 2022: Glasgow, UK April 2022 Notes: Oral Presentation.
Wild T, Foglia E, Hedrick H, Rintoul N, Ades A, Herrick H: Delivery Room Resuscitation of Neonates with Congenital Diaphragmatic Hernia; Lessons Learned through Video Review International Congenital Diaphragmatic Hernia Symposium 2022, Glasgow, UK April 2022 Notes: Oral Presentation.
Wild T, Foglia E, Hedrick H, Rintoul N, Ades A, Herrick H: Lung Recruitment After Birth in Infants with Congenital Diaphragmatic Hernia. International Congenital Diaphragmatic Hernia Symposium 2022, Glasgow, UK April 2022 Notes: Oral Presentation.
Osborne AD, Corder W, Rintoul NE, Maschhoff KL, Taha DK, Christ L, Laje P, Connelly JC, Dorfman AT : Case Report: Premature closure of the ductus arteriosus with prenatal acetaminophen use requiring extracorporeal membrane oxygenation. Neonatal ECMO Session, 37th Annual Children's National Symposium: ECMO & the Advanced Therapies for Cardiac and Respiratory Failure, Keystone, CO February 2021 Notes: Virtual poster presentation.
Goldshore M, Orlinsky R, Land S, Rintoul N, Hedrick H, Reynolds T, Flohr S, Eppley E: Birth Admission Length-of-Stay and Hospital Readmission in Children with Congenital Diaphragmatic Hernia Pediatric Academic Societies (PAS), Virtual Meeting March 2021 Notes: Poster Presentation.
Gu H, Hedrick HL, Rintoul NE, Thom C: Extreme thrombocytosis in congenital diaphragmatic hernia patients suggests underlying splenic dysfunction during critical illness. Eastern Society of Pediatric Research (ESPR), Philadelphia, PA March 2021 Notes: Oral Poster Presentation - presented by Hanna Gu, MD.
Osborne AD, Corder W, Rintoul NE, Maschhoff KL, Taha DK, Christ L, Laje P, Connelly JC, Dorfman AT: Case Report: Premature closure of the ductus arteriosus with prenatal acetaminophen use requiring extracorporeal membrane oxygenation Neonatal ECMO Session, 37th Annual Children's National Symposium: ECMO & the Advanced Therapies for Cardiac and Respiratory Failure, Keystone, CO February 2021: Virtual poster presentation March 2021.
Orlinsky R, Land S, Rintoul N, Goldshore M, Hedrick H: Birth Admission Length-of-Stay and Hospital Readmission in Children with Congenital Diaphragmatic Hernia. Pediatric Academic Societies (PAS), virtual due to COVID 2021.
Kesman R, Naim M, Rychik J, O'Byrne M, Ades A, Rintoul N: Associations between Delivery Room Management and Balloon Atrial Septostomy in D-Transposition of the Great Arteries. Cardiology 2020: Annual Update on Pediatric and Congenital Heart Disease, Lake Buena Vista, Florida February 2020 Notes: Poster Presentation.
Chotzoglou E, Goldshore M, Franciscovich C, Connelly, JT, Rintoul NE, Hedrick HL: Mode of ventilation and medical therapies applied on extracorporeal membrane oxygenation in infants with congenital diaphragmatic hernia. Eastern Society for Pediatric Research (ESPR), Philadelphia, PA March 2020 Notes: Poster presentation (cancelled due to Covid 19).
Pawlowski T, Stoller S, Rintoul N, Fraga M: Point-of-care ultrasound for evaluation of ECMO cannula position in neonates Eastern Society for Pediatric Research (ESPR), Philadelphia, PA March 2020 Notes: Platform Presentation (cancelled due to Covid 19).
Agarwal P, Natar G, Digeronimo R, Keene S, Massaro A, Sullivan KM, Rao R, Zaniletti I, Nguyen A, Billimoria Z, Dirnberger D, Rinoul N: Venovenous versus Venoarterial Extracorporeal Membrane Oxygenation among Infants with Hypoxic Ischemic Encephalopathy: Is There a Difference in Outcome? Pediatric Academic Societies (PAS) Annual Meeting, Philadelphia, PA May 2020 Notes: Poster presentation (Cancelled due to Covid 19).
Agarwal P, Natar G, Digeronimo R, Keene S, Massaro A, Sullivan KM, Rao R, Zaniletti I, Nguyen A, Billimoria Z, Dirnberger D, Rintoul N: Does Extracorporeal Membrane Oxygenation Increase Risk of Death or Intracranial Hemorrhage among Infants with Hypoxic Ischemic Encephalopathy and Persistent Pulmonary Hypertension? Pediatric Academic Societies (PAS) Annual Meeting, Philadelphia, PA May 2020 Notes: Poster presentation (Cancelled due to Covid 19).
Billimoria Z, DiGeronimo R, Chapman R, Gray B, Keene S, Weems M, Cleary J, Daniel JM, Dirnberger D, Seabrook R, Najaf T, Sullivan KM, Rintoul, N: Variation in Peri-surgical Anti-coagulation Practices in Congenital Diaphragmatic Hernia Patients on Extracorporeal Membrane Oxygenation. Pediatric Academic Societies (PAS) Annual Meeting, Philadelphia, PA, May 2020 Notes: Poster presentation (Cancelled due to Covid 19).
Billimoria Z, DiGeronimo R, Chapman R, Gray B, Keene S, Weems M, Cleary J, Daniel JM, Dirnberger D, Seabrook R, Najaf T, Sullivan KM, Rintoul, N: Variation in Surgical Practices in Congenital Diaphragmatic Hernia Patients on Extracorporeal Membrane Oxygenation Pediatric Academic Societies (PAS) Annual Meeting, Philadelphia, PA May 2020 Notes: Poster presentation (Cancelled due to Covid 19).
Chotzoglou E, Goldshore M, Franciscovich C, Connelly, JT, Rintoul NE, Hedrick HL: Mode of Ventilation and Therapies Applied on Extracorporeal Membrane Oxygenation in Infants with Congenital Diaphragmatic Hernia. Pediatric Academic Societies (PAS) Annual Meeting, Philadelphia, PA May 2020 Notes: Poster presentation (Cancelled due to Covid 19).
Coleman C, Billimoria Z, DiGeronimo R, Chapman R, Gray B, Keene S, Weems M, Cleary J, Daniel JM, Dirnberger D, Seabrook R, Najaf T, Sullivan KM, Rintoul, N: ECMO for Neonatal Respiratory Failure in Children's Hospital NICUs: How small is too small? Pediatric Academic Societies (PAS) Annual Meeting, Philadelphia, PA May 2020 Notes: Poster presentation (Cancelled due to Covid 19).
Grover T, Weems M, Haberman B, Brozanski B, Daniel JM, Rintoul N, Walden AR, Hedrick HL, Seabrook R, Murthy K, Keene S: Central line utilization and complications in infants with congenital diaphragmatic hernia (CDH). Pediatric Academic Societies (PAS) Annual Meeting, Philadelphia, PA May 2020 Notes: Poster presentation (Cancelled due to Covid 19).
Kesman R, Naim M, Rychik J, O'Byrne M, Ades A, Rintoul N: Associations between Delivery Room Management and Balloon Atrial Septostomy in D-Transposition of the Great Arteries. Pediatric Academic Societies (PAS) Annual Meeting, Philadelphia, PA May 2020 Notes: Poster Presentation (Cancelled due to Covid 19).
Kim M, Ades A, Fuller S, Okunowo O, Rintoul N, Naim M: Low Birth Weight Neonates Undergoing Cardiac Surgery: Have Outcomes Improved Over Time? Pediatric Academic Societies (PAS) Annual Meeting, Philadelphia, PA May 2020 Notes: Platform Presentation (Cancelled due to Covid 19).
O'Neill S, Sullivan SM, Gray B, Rintoul N: Morbidity and mortality of neonates with severe meconium aspiration syndrome and ECMO: an analysis from the Children's Hospital Neonatal Consortium. Pediatric Academic Societies (PAS) Annual Meeting, Philadelphia, PA May 2020 Notes: Poster presentation (Cancelled due to Covid 19).
Pallotto EK, Piazza A, Chuo J, Rintoul N: Can NICU perioperative handoff improve physiological parameters and team safety culture? Pediatric Academic Societies (PAS) Annual Meeting, Philadelphia, PA May 2020 Notes: Poster presentation (Cancelled due to Covid 19).
Pawlowski T, Stoller S, Rintoul N, Fraga M: Point-of-care ultrasound for evaluation of ECMO cannula position in neonates. Pediatric Academic Societies (PAS) Annual Meeting, Philadelphia, PA May 2020 Notes: Platform Presentation (Cancelled due to Covid 19).
Barrett K, Danzer E, Hedrick HL, Nelson O, Rintoul NE, Simpao AF : The impact of surgical management on anesthesia exposure during the first year of life in infants with giant omphalocele Society of Pediatric Anesthesia (SPA) November 2020.
Rintoul N. Panelist: "Inside Perfusion: Pediatric Respiratory Failure and the Role of VV ECMO", National Conference, Virtual. Oct 2022.
Rintoul N. "Would you, or Wouldn't you? Interactive Cases" 33rd Annual Extracorporeal Life Support Organization (ELSO) Conference, Boston, MA. Sept 2022.
Rintoul N. Chair Neonatal ECMO session, EURO ELSO, London, England. May 2022.
Rintoul N. "ECPR in Neonates - criteria for support and outcomes", EURO ELSO, London, England. May 2022.
Rintoul N. "Advances in Neonatal ECMO", EURO ELSO, London, England. May 2022.
Rintoul N. "Prenatal Brain Maturation in Neonates with Congenital Diaphragmatic Hernia". Platform presentation. International Congenital Diaphragmatic Hernia Symposium. Glasgow, UK. Apr 2022.
Rintoul N. "Lung Aeration After Birth in Infants with Congenital Diaphragmatic Hernia". Platform Presentation. International Congenital Diaphragmatic Hernia Symposium, Glasgow, Scotland. Apr 2022.
Rintoul N. "Delivery Room Resuscitation of Neonates with CDH; Lessons Learned through Video Review". Platform Presentation. International Congenital Diaphragmatic Hernia Symposium, Glasgow, Scotland. Apr 2022.
Rintoul N. "Treprostinil in children with congenital diaphragmatic hernia-related pulmonary hypertension". Platform presentation. International Congenital Diaphragmatic Hernia Symposium, Glasgow, Scotland. Apr 2022.
Rintoul N. "Expansion of the Prenatal Phenotype of PIEZO1 mutations" American College of Medical Genetics Annual Conference, Nashville, Tennessee. Mar 2022.
Rintoul N. "Practice Variation in Perceived Optimal Genetic Testing Across CHNC ECMO Centers". Platform Presentation. 38th Annual Children's National Symposium: ECMO & the Advanced Therapies for Cardiovascular and Respiratory Failure. Feb 2022.
Rintoul N. "Ask the Expert", ECMO conference, Guangzhou, China, virtual due to COVID. Nov 2021.
Rintoul N. "Postnatal Management of Congenital Diaphragmatic Hernia", 11th International Neonatology Conference on Hottest Topics in Neonatal Medicine, Abu Dhabi, virtual due to COVID. Oct 2021.
Rintoul N. "FETO and Severe Diaphragmatic Hernia", Connecticut Children's Journal Club, Connecticut Children's Medical Center, virtual due to COVID. Sept 2021.
Rintoul N. Neonatal Respiratory Failure, Extracorporeal Life Support Organization (ELSO) International Neonatal/Pediatric ECMO Course, virtual due to COVID. Mar 2021.
Rintoul N. Panelist: Neonatal ECMO, Extracorporeal Life Support Organization (ELSO) International Neonatal/Pediatric ECMO Course, virtual due to COVID. Mar 2021.
Rintoul N. "Case Report: Premature closure of the ductus arteriosus with prenatal acetaminophen use requiring extracorporeal membrane oxygenation" Neonatal ECMO Session, 37th Annual Children's National Symposium: ECMO & the Advanced Therapies for Cardiac and Respiratory Failure, virtual due to COVID. Feb 2021.
Rintoul N. "CRRT for Cytokine Removal in a Neonatal Patient with Septic Shock and CDH on ECMO", 37th Annual Children's National symposium: ECMO & the Advanced Therapies for Cardiac & Respiratory Failure Conference, virtual due to COVID. Feb 2021.
Rintoul N. "Adjunct Therapies on ECMO", Neonatal-Infant ECMO International Forum and Workshop, Guangzhou, China (virtual due to COVID). Nov 2020.
Rintoul N. "Managing Bleeding and Thrombotic Complications", Pediatric ECMO Anticoagulation Collaborative (PEACE) Expert Panel Meeting, Baltimore, Maryland (virtual due to COVID). Nov 2020.
Rintoul N. CHNC Focus Group Presentations (Round II) - ECMO, 2020 CHNC Virtual Annual Symposium Program, virtual due to COVID. Oct 2020.
Rintoul N. "Pulmonary Hypertension in Congenital Diaphragmatic Hernia", 31st Annual Extracorporeal Life Support Organization (ELSO) Conference, Hawaii (virtual due to COVID), Platform Oral Presentation. Sept 2020.
Rintoul N. "ECMO and Prematurity: How young is too young?", Platform oral presentation, 31st Annual Extracorporeal Life Support Organization (ELSO) Conference, Hawaii (virtual due to COVID). Sept 2020.
Rintoul N. "Low Birth Weight Neonates Undergoing Cardiac Surgery: Have Outcomes Improved Over Time?", Pediatric Academic Societies (PAS), Neonatology Webinar Series. Jul 2020.
Rintoul N. "At The Tip of Your Tongue: Voice-Guided Procedural Checklists for Healthcare", Platform oral presentation, AMIA Clinical Informatics Conference, Seattle, WA. May 2020.
Rintoul N. "Treatment of Pulmonary Hypertension in Congenital Diaphragmatic Hernia", Platform oral presentation, keynote address 36th Annual Children's National symposium: ECMO & the Advanced Therapies for Cardiac & Respiratory Failure Conference. February 25, 2020. Keystone, Colorado. Feb 2020.
Rintoul N. "Delayed Cord Clamping", Platform oral presentation, The International Congenital Diaphragmatic Hernia Symposium, Houston, TX. Feb 2020.
Rintoul N. "Infant's first blood gas predicts required therapies at 30 days of life in infants with Congenital Diaphragmatic Hernia", Platform oral presentation, The Congenital Diaphragmatic Hernia Symposium, Houston, TX. Feb 2020.
Rintoul N. "Therapy at 30 days of life predicts lung function at 6-12 months in infants with Congenital Diaphragmatic Hernia", Platform oral presentation, The Congenital Diaphragmatic Hernia Symposium, Houston, TX. Feb 2020.
Rintoul N. "Does Extracorporeal Membrane Oxygenation Increase Risk of Death or Intracranial Hemorrhage among Infants with Hypoxic Ischemic Encephalopathy and Persistent Pulmonary Hypertension?"
Neonatal Consortium (CHNC) ECMO and HIE focus groups (Bradley Hill - Innovation Award for Best Abstract). 36th Annual Children's National symposium: ECMO & the Advanced Therapies for Cardiac & Respiratory Failure Conference Keystone, Colorado. Feb 2020.
Rintoul N. "Novel Decision Aids and Technology in Neonatal Resuscitation", Platform oral presentation, The International Congenital Diaphragmatic Hernia Symposium, Houston, TX. Feb 2020.
Rintoul N. "Venovenous versus Venoarterial Extracorporeal Membrane Oxygenation among Infants with Hypoxic Ischemic Encephalopathy: Is There a Difference in Outcome?" Children's Hospital Neonatal Consortium (CHNC) ECMO and HIE focus groups 36th Annual Children's National symposium: ECMO & the Advanced Therapies for Cardiac & Respiratory Failure Conference, Keystone, Colorado. Feb 2020.
Rintoul N. "Moderator CDH Research session", International Congenital Diaphragmatic Hernia Symposium, Houston, TX. Feb 2020.
Rintoul N. "ECMO for Neonatal Respiratory Failure in Children's Hospital NICUs: How small is too small?" 36th Annual Children's National symposium: ECMO & the Advanced Therapies for Cardiac & Respiratory Failure Conference. Keystone, Colorado. Feb 2020.
Rintoul N. Does Trisomy 21 Impact Outcomes in Neonatal Medical ECMO? Keystone, Colorado. Feb 2020.
2016, Faculty Honor Roll, The Children's Hospital of Philadelphia
2016, Sprint, "Critical Knowledge Project", Office of Entrepreneurship & Innovation, Children's Hospital of Philadelphia
2015, Alan R. Cohen Master Clinician Award, Children's Hospital of Philadelphia, Department of Pediatrics
2011, Suburban Life Magazine February 2011 "Best Doctor" Award, Norristown, PA
2011, 2014-2015, ELSO "Excellence in Life Support" Award, The Children's Hospital of Philadelphia
2002, Department of Pediatrics Annual Teaching Award, Queen's University, Kingston, Ontario
1995, Highest Standing in Urology, Queen's University, Kingston, Ontario
1993, Adiel Steacy Memorial Scholarship, Queen's University, Kingston, Ontario
1993, Aesculapian Society Award of Merit, Queen's University, Kingston, Ontario
1991, First Class Honors, Bachelor of Science, Queen's University, Kingston, Ontario
1991, Medicine Entrance Scholarship, Queen's University, Kingston, Ontario
1990, Dean's Special Award, Queen's University, Kingston, Ontario
1990, Dean's Honor List, Queens University, Kingston, Ontario
1989, James H. Rattray Memorial Scholarship in Science, Queen's University, Kingston, Ontario
2021-present, Periodic Reviewer, Fetal Diagnosis and Therapy
2021-present, Periodic Reviewer, European Journal of Pediatrics
2021-present, Periodic Reviewer, Journal of Perinatology
2019-present, Periodic Reviewer, The American Journal of Perinatology
2018-present, Periodic Reviewer, American Society for Artificial Internal Organs
2015-present, Periodic Reviewer, Annals of Surgery
2015-present, Periodic Reviewer, Archives of Disease in Childhood
2020-present, CHNC Erase Post-Op Pain Quality Improvement Project
2020-present, CHNC CDH Surgery/Anticoagulation Survey Project
2020-present, Perfluorcarbon Oversight Committee
2020-present, Birth Defects Biorepository Steering Committee (CFDT)
2019-present, Neonatal Surgery QI Working Group
2019-present, University City Inpatient Expansion: Patient Care Unit Workshop Committee
2019-present, Penn Engineering OEI Project: PIV Infiltrate
2019-present, Unit Leadership Partners Committee
2019-present, Neonatal Surgery ID Team
2019-present, ECMO Radiology Project Committee,
2019-present, Fetal Research Oversight Committee
2019-present, Co-Chair, SDU/NICU Operation Committee
2019-present, ICU Leadership Collaboration Committee
2018-present, Physician Lead, West 1 Nursing
2018-present, NICU Cohorting Project
2018-present, Biorepository Project
2018-present, Vein of Galen Malformation working group
2018-present, Delayed Cord Clamping in the Special Delivery Unit (SDU) working group
2017-present, Research Oversight Committee, Center for Fetal Diagnosis and Treatment
2017-present, Biorepository Committee
2017-present, Physician lead, Perioperative/Neosurgery QI working group
2017-present, Physician lead, Neonatal ECMO QI working group
2016-present, Perinatal Nephrology Group
2016-present, NICU Clinical Affairs Committee
2015-present, Ongoing Professional Performance Evaluation (OPPE) QI Team
2014-present, Fetal Neuroprotection Committee
2012-present, Neonatal Executive Committee
2011-present, Chair, Neosurgery Operations Committee
2009-present, N/IICU Steering Committee
2008-present, Chair, Special Delivery Unit Operations Committee
2007-present, Chair, Neonatal Perioperative Operations Committee
2004-present, Neonatal QI Committee
2004-present, N/IICU Quality and Patient Safety Committee
2004-present, ECMO Operations Committee
2022-present, PediECMO
2017-present, Children's Hospital Neonatal Consortium (CHNC) Perioperative Collaborative
- 2018-present, Physician Lead, Extracorporeal Membrane Oxygenation (ECMO) Focus Group
- 2020-present, Fetal Therapy Focus Group
- 2019-present, Co Physician Lead, CIQI Erase Pain Project: Focusing on Perioperative Pain
- 2018-present, Congenital Diaphragmatic Hernia Focus Group
- 2017-present, Site PI, Stepp-In Next Steps