Natalie E. Rintoul, MD

Natalie E. Rintoul, MD, is an attending neonatologist at CHOP. She co-directs the Neonatal Surgical Team and is medical director of the Neonatal ECMO Program.

Areas of Expertise: Neonatal ECMO, Neonatal Surgery
Locations: Main Campus
Phone: 215-590-1653

  • Background

    Natalie Rintoul, MD, is an assistant professor at the University of Pennsylvania School of Medicine and attending neonatologist at The Children's Hospital of Philadelphia.

    After receiving her medical degree at Queen's University in Canada, Dr. Rintoul completed her pediatric residency at Massachusetts General Hospital in Boston and her neonatal fellowship at The Children's Hospital of Philadelphia.

    Dr. Rintoul is not only interested in the care of the neonate with congenital anomalies requiring neonatal surgery, but also those neonates requiring heart-lung bypass (ECMO). She is co-director of the Neonatal Surgical Team, and medical director of the Neonatal ECMO Program. She is also a fetal consultant for the Center for Fetal Diagnosis and Treatment.

    Dr. Rintoul’s research interests include management of myelomeningocele, pulmonary hypoplasia and pulmonary hypertension in congenital diaphragmatic hernia, and perioperative care of the surgical neonate. She is the chair of the Neonatal Perioperative Committee. Dr. Rintoul is also a key member of the Special Delivery Unit, involved in the creation and implementation of delivery room guidelines for infants with congenital anomalies.

  • Education and Training

    Medical School

    MD - Queen's University School of Medicine, Kingston, Ontario, Canada


    Pediatrics - Massachusetts General Hospital, Harvard University, Boston, MA


    Neonatal-Perinatal Medicine - The Children's Hospital of Philadelphia, Philadelphia, PA

    Board Certification

    Neonatal-Perinatal Medicine

  • Titles and Academic Titles

    Attending Neonatologist

    Assistant Professor, Perelman School of Medicine at the University of Pennsylvania

  • Departments and Services
  • Research Interests

    Pulmonary hypertension
    Pulmonary hypoplasia
    Perioperative care of the surgical neonate
    Neonatal resuscitation

  • Publications



    Danzer E, Gerdes M, D'Agostino JA, Bernbaum J, Hoffman C, Herkert L, Rintoul NE, Peranteau WH, Flake AW, Adzick NS, Hedrick HL. Neurodevelopmental outcome at one year of age in congenital diaphragmatic hernia infants not treated with extracorporeal membrane oxygenation. J Pediatr Surg. 2015 Jun;50(6):898-903. doi: 10.1016. Read the abstract.

    Partridge EA, Peranteau WH, Rintoul NE, Herkert LM, Flake AW, Adzick NS, Hedrick HL. Timing of repair of congenital diaphragmatic hernia in patients supported by extracorporeal membrane oxygenation (ECMO). J Pediatr Surg. 2015 Feb;50(2):260-2. Read the abstract.

    Partridge EA, Hanna BD, Rintoul NE, Herkert L, Flake AW, Adzick NS, Hedrick HL, Peranteau WH. Brain-type natriuretic peptide levels correlate with pulmonary hypertension and requirement for extracorporeal membrane oxygenation in congenital diaphragmatic hernia. J Pediatr Surg. 2015 Feb;50(2):263-6. Read the abstract.

    Danzer E, Gerdes M, D'Agostino JA, Bernbaum J, Hoffman C, Rintoul NE, Herkert LM, Flake AW, Adzick NS, Hedrick HL. Patient characteristics are important determinants of neurodevelopmental outcome during infancy in giant omphalocele. Early Hum Dev. 2015 Feb 9;91(3):187-193. Read the abstract.

    Peranteau WH, Tharakan SJ, Partridge E, Herkert L, Rintoul NE, Flake AW, Adzick NS, Hedrick HL. Systemic hypertension in giant omphalocele: An underappreciated association. J Pediatr Surg. 2015 Feb 23. pii: S0022-3468(15)00131-1. doi: 10.1016. Read the abstract