Jeffrey Roizen, MD, PhD, FAAP

Jeffrey Roizen, MD, PhD, FAAP, is an attending physician at The Children's Hospital of Philadelphia who specializes in treating patients with diabetes, hyperinsulinism, endocrine and other disorders.

Areas of Expertise: Metabolic bone disease, Pituitary disease, Hypercalcemia, Hyperparathyroidism, Obesity, Type 1 Diabetes, Type 2 Diabetes
Locations: Main Campus
Appointments and Referrals: 1-800-TRY-CHOP (1-800-879-2467)

  • Background

    Dr. Roizen is a clinician scientist at The Children’s Hospital of Philadelphia.

    His clinical interests include metabolic bone diseases with a focus on vitamin D metabolism, hyperparathyroidism and pseudohypoparathyroidism as well as obesity, type 2 diabetes and type 1 diabetes.
    Dr. Roizen works under the mentorship of Dr. Levine and Dr. Hakonarson. Each of whom has an active laboratory research program that complements and extends his clinical studies.

    Dr. Roizen has more than 30 papers, patents and chapters.

    He is a member of numerous professional societies, including the American Society for Bone and Mineral Research, the Endocrine Society, the Pediatric Endocrine Society and the American Diabetes Association. He is a Fellow of the American Academy of Pediatrics.

  • Education and Training

    Medical School

    MD - Washington University School of Medicine, Saint Louis, MO


    Pediatrics - The Children's Hospital of Philadelphia, Philadelphia, PA


    Pediatric Endocrinology - The Children's Hospital of Philadelphia, Philadelphia, PA

    Graduate Degree

    PhD - Washington University School of Medicine, Saint Louis, MO

  • Titles and Academic Titles

    Attending Physician

  • Departments and Services
  • Research Interests

    Vitamin D metabolism and action|
    Prader-Willi Syndrome

  • Publications



    Roizen JD, Levine MA, and Carlow, D. 2012 Application of Vitamin D Status to Development of normal Ranges for Serum Calcium Concentration in the Pediatric Population. ASBMR 2012.

    Roizen JD, Sasson I, Levine MA. Modulation of CYP2R1 expression: A Potential Mechanism for Determining Vitamin D Requirements in Aging and Obesity. ENDO Society 2012.

    Roizen JD, Zhou J, and Levine MA. Polymorphisms in the CYP2R1 Gene Present in the General Population Affect 25-hydroxylase Activity. ASBMR 2012.


    Roizen JD, Levine MA: Nature and Nurture: Multifactorial rickets in two pre-school aged children. PAS Annual Conference 2011.



    Roizen, J. and Levine, MA. A meta-analysis comparing the Biochemistry of Primary Hyperparathyroidism in Youths to the Biochemistry of Primary Hyperparathyroidism in Adults. J Clin Endocrinol Metab: 2014; Dec;99(12):4555-64. jc20142268.

    Roizen, MF and Roizen JD. Vitamin D and your patients: don't accept wimpy. Anesth Analg 2014;119(3): 503-505.


    Roizen JD, Shah V, Levine MA, Carlow DC. Determination of reference intervals for serum total calcium in the vitamin D-replete pediatric population. J Clin Endocrinol Metab. 2013 Dec;98(12):E1946–50.

    Roizen J*, Xi D*, Lai M, Gandhi N, Kublaoui B. Paraventricular nucleus Sim1 neuron ablation mediated obesity is resistant to high fat diet. PLoS ONE. Public Library of Science; 2013;8(11):e81087.
    (*Co-first authors)

  • Awards and Honors

    2015, Pediatric Endocrine Society Clinical Scholar Award
    2013, Endocrine Society AMGEN Endocrine Scholars Award
    2013, Pediatric Endocrine Society Research Fellowship

  • Editorial and Academic Positions
    Editorial Positions

    Reviewer, Journal of Clinical Endocrinology and Metabolism

    Academic and Institutional Committees

    Committee Member – Pediatric Endocrine Society Obesity Committee
    Board Member – Philadelphia Endocrine Society