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Ronald Rubenstein, MD, PhD

Attending Pulmonologist

Director, Cystic Fibrosis Center

Original Papers

Yan W, Samaha FF, Ramkumar M, Kleyman TR, Rubenstein RC.  CFTR Differentially Regulates Human and Murine Epithelial Sodium Channels in Xenopus Oocytes. J Biol Chem. 2004 May 28; 279 (22):23183-92. Cited in PubMed; PMID: 15047694.

Samaha FF, Rubenstein RC, Yan W, Ramkumar M, Levy DI, Ahn YJ, et al.  Functional Polymorphism in the Carboxyl Terminus of the Alpha Subunit of the Epithelial Sodium Channel Alters Surface Expression in Xenopus Oocytes. J Biol Chem. 2004 Jun 4; 279 (23):23900-7. Cited in PubMed; PMID: 15069064.

Yan W, Suaud L, Kleyman TR, Rubenstein RC. Differential Modulation of a Polymorphism in the Carboxyl Terminus of the Alpha Subunit of the Human Epithelial Sodium Channel by Protein Kinase C d. Am. J. Physiol.-Renal Physiol. 2006 Feb; 290(2):F279-88. Cited in PubMed; PMID: 16174865.

Goldfarb SB, Kashlan OB, Watkins JN, Suaud L, Yan W, Kleyman TR,et al. Differential Effects of Hsc70 and Hsp70 on the Intracellular Trafficking and Functional Expression of Epithelial Sodium Channels. Proc. Nat. Acad. Sci. U.S.A., 2006 Apr 11; 103(15):5817-22. Cited in PubMed; PMID: 16585520.

Rubenstein RC. Abnormal Regulatory Interactions of I148T-CFTR and the Epithelial Na+ Channel in Xenopus Oocytes. Am. J. Physiol Cell Physiol, 2007 Jan;292(1):C603-11. Cited in PubMed; PMID: 16822950.

Antunes MB, Woodworth BA, Bhargave G, Xiong G, Aguilar JL, Ratner AJ, et al. Murine nasal septa for respiratory epithelial air-liquid interface cultures. Biotechniques. 2007 Aug;43(2):195-6, 198, 200 passim. Cited in PubMed; PMID: 17824387.

Kashlan OB, Mueller GM, Qamar MZ, Poland PA, Abner A, Rubenstein RC, et al. Small heat shock protein alphaA-crystallin regulates epithelial sodium channel expression.  J Biol Chem. 2007 Sep 21;282(38):28149-56. Epub 2007 Jul 30. Cited in PubMed; PMID: 17664274.

Suaud L, Yan W, Carattino MD, Robay A, Kleyman TR, Rubenstein RC. Regulatory interactions of N1303K-CFTR and ENaC in Xenopus oocytes: evidence that chloride transport is not necessary for inhibition of ENaC. Am J Physiol Cell Physiol. 2007 Apr;292(4):C1553-61. Epub 2006 Dec 20. Cited in PubMed; PMID: 17182731.

Yan W, Spruce L, Rosenblatt MM, Kleyman TR, Rubenstein RC. Intracellular trafficking of a polymorphism in the COOH terminus of the alpha-subunit of the human epithelial sodium channel is modulated by casein kinase 1. Am J Physiol Renal Physiol. 2007 Sep;293(3):F868-76. Epub 2007 Jun 27. Cited in PubMed;PMID: 17596527.

Rubenstein RC. Targeted therapy for cystic fibrosis: cystic fibrosis transmembrane conductance regulator mutation-specific pharmacologic strategies.  Mol Diagn Ther. 2006;10(5):293-301. Review. Cited in PubMed; PMID: 17022692.

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