Eduardo Ruchelli, MD

Eduardo Ruchelli, MD, is an attending pathologist who works with the Congenital Hyperinsulinism Center and the Division of Anatomic Pathology at CHOP.

Areas of Expertise: Fetal and perinatal pathology, Pathologic evaluation of the pancreas in congenital hyperinsulinism, Pediatric liver and gastrointestinal diseases
Locations: Main Campus
Appointments and Referrals: 1-800-TRY-CHOP (1-800-879-2467)

  • Education and Training

    Medical School

    MD - University of Buenos Aires School of Medicine, Argentina


    Hospital of the Medical College of Pennsylvania, Philadelphia, PA


    Children's Hospital of Pittsburgh, Pittsburgh, PA


    Magee-Women's Hospital, Pittsburgh, PA

    Board Certification

    Anatomic and Clinical Pathology
    Pediatric Pathology

  • Titles and Academic Titles

    Attending Pathologist

    Director, Pediatric Pathology Fellowship Program

  • Departments and Services
  • Research Interests

    Congenital hyperinsulinism
    Eosinophilic esophagitis

  • Publications



    Ernst L, Grossman A, Ruchelli E. Familial Perinatal Liver Disease and Fetal Thrombotic Vasculopathy. Pediatr Dev Pathol 2008;11:160-163.

    Spinner NB, Saitta SC, Delaney DP, Colliton R, Zderic SA, Ruchelli E, Zackai E, Kolon T. Intracytoplasmic sperm injection (ICSI) with transmission of a Ring Y chromosome and ovotesticular disorder of sex development in offspring. Am J Med Genet 2008;146A:1828-31.

    Danzer E, Davey MG, Kreiger PA, Ruchelli ED, Johnson MP, Adzick NS, Flake AW, Hedrick HL. Fetal Tracheal Occlusion for Severe Congenital Diaphragmatic Hernia in Humans: A Morphometric Study of Lung Parenchyma and Muscularization of Pulmonary Arterioles. J Pediatr Surg 2008; 43:1767–1775.


    Hardy OT, Hernandez-Pampaloni M, Saffer JR, Suchi M, Ruchelli E, Zhuang H, Ganguly A, Freifelder R, Adzick NS, Alavi A, Stanley CA.. Diagnosis and localization of focal congenital hyperinsulinism by 18F-fluorodopa PET scan. J Pediatr 2007;150:140-5.

    Liacouras CA, Bonis P, Putnam PE, Straumann A, Ruchelli E, Gupta SK, Lee JJ, Hogan SP, Wershil BK, Rothenberg ME, Ackerman SJ, Gomes I, Murch S, Mishra A, Furuta GT. Summary of the First International Gastrointestinal Eosinophil Research Symposium. J Pediatr Gastroenterol Nutr 2007;45:370-91.

    Davey M, Shegu S, Danzer E, Ruchelli E, Adzick S, Flake A, Hedrick HL. Pulmonary arteriole muscularization in lambs with diaphragmatic hernia after combined tracheal occlusion/glucocorticoid therapy. Am J Obstet Gynecol 2007;197:381.


    Suchi M, MacMullen C, Thornton PS, Adzick NS, Ganguly A, Ruchelli ED, Stanley CA. Molecular and Immunohistochemical Analyses of the Focal Form of Congenital Hyperinsulinism. Mod Pathol 2006;1:122-9

    Liechty KW, Hedrick HL, Hubbard AM, Johnson MP, Wilson RD, Ruchelli ED, Howell LJ, Crombleholme TM, Flake AW, Adzick NS. Severe pulmonary hypoplasia associated with giant cervical teratomas. J Pediatr Surg 2006;41:230-3.

    Kreiger PA, Ruchelli ED, Mahboubi S, Hedrick H, Adzick NS, Russo PA. Fetal pulmonary malformations: defining histopathology. Am J Surg Pathol. 2006;30:643-9.

    Iyoob SD, Tsai A, Ruchelli ED, Coleman BG, Wilson RD. Large umbilical cord hemangioma: sonographic features with surgical pathologic correlation. J Ultrasound Med. 2006;25:1495-8.


    Liacouras CA, Spergel JM, Ruchelli E, Verma R, Mascarenhas M, Semeao E, Flick J, Kelly J, Brown-Whitehorn T, Mamula P, Markowitz J. Eosinophilic Esophagitis: A 10 year experience in 381 children. Clin Gastroenterol Hepatol  2005;3:1198-1206


    Adzick NS, Thornton PS, Stanley CA, Kaye R, Ruchelli E. A multidisciplinary approach to the focal form of congenital hyperinsulinism leads to successful treatment by partial pancreatectomy. J Pediatr Surg 2004;39:270-5

    Suchi M, Thornton PS, Adzick NS, MacMullen C, Ganguly A, Stanley CA, Ruchelli ED. Congenital hyperinsulinism: intraoperative biopsy interpretation can direct the extent of pancreatectomy. Am J Surg Pathol 2004;28:1326-1335

    Liacouras CA, Ruchelli E. Eosinophilic esophagitis. Curr Opin Pediatr 2004;16:560-566 


    Fogg MI, Ruchelli E, Spergel JM. Pollen and eosinophilic esophagitis. J Allergy Clin Immunol 2003; 112:796-7