Jonathan Spergel, MD, PhD

Papers

2022

Zhang S, Shoda T, Aceves SS, Arva NC, Chehade M, Collins MH, Dellon ES, Falk GW, Gonsalves N, Gupta SK, Hirano I, Khoury P, Leung J, Spergel AKR, Spergel JM, Wechsler JB, Yang GY, Furuta GT, Rothenberg ME; Consortium of Eosinophilic Gastrointestinal Disease Researchers (CEGIR) Investigators Group. Mast cell-pain connection in eosinophilic esophagitis. Allergy. 2022 Feb 17. Doi 10.1111/all.15260. Epub ahead of print. PMID: 35175645.

Sehgal S, Gupta RS, Wlodarski M, Bilaver LA, Wehbe FH, Spergel JM, Wang J, Ciaccio CE, Makhija M, Starren JB. Development of Food Allergy data dictionary: towards a Food Allergy Data Commons. J Allergy Clin Immunol Pract. 2022 Mar 5:S2213-2198(22)00225-2. doi: 10.1016/j.jaip.2022.02.024. Epub ahead of print. PMID: 35259539.

Chang X, March M, Mentch F, Nguyen K, Glessner J, Qu H, Liu Y, Furuta G, Aceves S, Gonsalves N, Nadeau K, Cianferoni A, Spergel J, Sleiman P, Hakonarson H. A genome-wide association meta-analysis identifies new eosinophilic esophagitis loci. J Allergy Clin Immunol. 2022 Mar;149(3):988-998. doi: 10.1016/j.jaci.2021.08.018. Epub 2021 Sep 25. PMID: 34506852.

Hara T, Kasagi Y, Wang J, Sasaki M, Aaron B, Karami A, Shimonosono M, Shimonosono R, Maekawa H, Dolinsky L, Wilkins B, Klein J, Wei J, Nunes K, Lynch K, Spergel JM, Hamilton KE, Ruffner MA, Karakasheva TA, Whelan KA, Nakagawa H, Muir AB. CD73+ Epithelial Progenitor Cells That Contribute to Homeostasis and Renewal Are Depleted in Eosinophilic Esophagitis. Cell Mol Gastroenterol Hepatol. 2022 Jan 30:S2352-345X(22)00018-2. doi: 10.1016/j.jcmgh.2022.01.018. Epub ahead of print. PMID: 35108658.

Spergel BL, Ruffner MA, Godwin BC, Liacouras CA, Cianferoni A, Gober L, Hill DA, Brown-Whitehorn TF, Chaiboonma K, Aceves SA, Muir AM, Spergel JM. Improvement in eosinophilic esophagitis when using dupilumab for other indications or compassionate use. Ann Allergy Asthma Immunol. 2022 Jan 25:S1081-1206(22)00020-5. doi: 10.1016/j.anai.2022.01.019. Epub ahead of print. PMID: 35085819.

Nguyen K, Greenthal E, Sorscher S, Lurie P, Spergel JM, Kennedy K. Adverse events and labeling issues related to suspected sesame allergy reported in an online survey. Ann Allergy Asthma Immunol. 2022 Mar;128(3):279-282. doi: 10.1016/j.anai.2021.12.005. Epub 2021 Dec 7. PMID: 34883240.

Shoda T, Collins MH, Rochman M, Wen T, Caldwell JM, Mack LE, Osswald GA, Besse JA, Haberman Y, Aceves SS, Arva NC, Capocelli KE, Chehade M, Davis CM. Dellon ES, Falk GW, Gonsalves N, Gupta SK, Hirano I, Khoury P, Klion A, Menard- Katcher C, Leung J, Mukkada V, Putnam PE, Spergel JM, Wechsler JB, Yang GY, Furuta GT, Denson LA, Rothenberg ME; Consortium of Eosinophilic Gastrointestinal Diseases Researchers (CEGIR). Evaluating Eosinophilic Colitis as a Unique Disease using Colonic Molecular Profiles: A Multi-Site Study. Gastroenterology. 2022 Jan 25:S0016-5085(22)00038-5. doi: 10.1053/j.gastro.2022.01.022. Epub ahead of print. PMID: 35085569.

Stidham S, Villareal V, Chellappa V, Yoder L, Alley O, Shreffler W, Spergel J, Fleischer D, Sampson H, Gilboa-Geffen A. Aptamer based point of care diagnostic for the detection of food allergens. Sci Rep. 2022 Jan 25;12(1):1303. doi: 10.1038/s41598-022-05265-0. PMID: 35079047; PMCID: PMC8789827.

Hiremath G, Sun L, Correa H, Acra S, Collins MH, Bonis P, Arva NC, Capocelli KE, Falk GW, King E, Gonsalves N, Gupta SK, Hirano I, Mukkada VA, Martin LJ, Putnam PE, Spergel JM, Wechsler JB, Yang GY, Aceves SS, Furuta GT, Rothenberg ME, Koyama T, Dellon ES. Development and Validation of Web-Based Tool to Predict Lamina Propria Fibrosis in Eosinophilic Esophagitis. Am J Gastroenterol. 2022 Feb 1;117(2):272-279. doi: 10.14309/ajg.0000000000001587. PMID: 34932022; PMCID: PMC8858426.

Shoda T, Wen T, Caldwell JM, Ben-Baruch Morgenstern N, Osswald GA, Rochman M, Mack LE, Felton JM, Abonia JP, Arva NC, Atkins D, Bonis PA, Capocelli KE, Collins MH, Dellon ES, Falk GW, Gonsalves N, Gupta SK, Hirano I, Leung J, Menard-Katcher PA, Mukkada VA, Putnam PE, Rudman Spergel AK, Spergel JM, Wechsler JB, Yang GY, Aceves SS, Furuta GT, Rothenberg ME; Consortium of Eosinophilic Gastrointestinal Disease Researchers (CEGIR) Investigators Group. Loss of Endothelial TSPAN12 Promotes Fibrostenotic Eosinophilic Esophagitis vi Endothelial Cell-Fibroblast Crosstalk. Gastroenterology. 2022 Feb;162(2):439-453. doi: 10.1053/j.gastro.2021.10.016. Epub 2021 Oct 21. PMID: 34687736; PMCID: PMC8792211.

Hirano I, Collins MH, King E, Sun Q, Chehade M, Abonia JP, Bonis PA, Capocelli KE, Dellon ES, Falk GW, Gonsalves N, Gupta SK, Leung J, Katzka D, Menard-Katcher P, Khoury P, Klion A, Mukkada VA, Peterson K, Shoda T, Rudman- Spergel AK, Spergel JA, Yang GY, Rothenberg ME, Aceves SS, Furuta GT; CEGIR investigators. Prospective Endoscopic Activity Assessment for Eosinophilic Gastritis in a Multisite Cohort. Am J Gastroenterol. 2022 Mar 1;117(3):413-423. doi: 10.14309/ajg.0000000000001625. PMID: 35080202; PMCID: PMC8897269.

2021

Spergel JM, Muir AB, Liacouras CA, Burke D, Lewis MO, Brown-Whitehorn T, Cianferoni A. Sustained milk consumption after 2 years post-milk epicutaneous immunotherapy for eosinophilic esophagitis. Allergy. 2021 May;76(5):1573-1576. PMID: 33202086.

Dribin TE, Schnadower D, Spergel JM, Campbell RL, Shaker M, Neuman MI, Michelson KA, Capucilli PS, Camargo CA Jr, Brousseau DC, Rudders SA, Assa'ad AH, Risma KA, Castells M, Schneider LC, Wang J, Lee J, Mistry RD, Vyles D, Pistiner M, Witry JK, Zhang Y, Sampson HA. Severity grading system for acute allergic reactions: A multidisciplinary Delphi study. J Allergy Clin Immunol. 2021 Jul;148(1):173-181. PMID: 33476673; PMCID: PMC8273088.

Ruffner MA, Hu A, Dilollo J, Benocek K, Shows D, Gluck M, Spergel JM, Ziegler SF, Hill DA, Cerosaletti K. Conserved IFN Signature between Adult and Pediatric Eosinophilic Esophagitis. J Immunol. 2021 Mar 15;206(6):1361-1371. PMID: 33558373; PMCID: PMC7946729.

Fujiogi M, Camargo CA Jr, Raita Y, Zhu Z, Celedón JC, Mansbach JM, Spergel JM, Hasegawa K. Integrated associations of nasopharyngeal and serum metabolome with bronchiolitis severity and asthma: A multicenter prospective cohort study. Pediatr Allergy Immunol. 2021 Jul;32(5):905-916. PMID: 33559342; PMCID: PMC8269431.

Dhudasia MB, Spergel JM, Puopolo KM, Koebnick C, Bryan M, Grundmeier RW, Gerber JS, Lorch SA, Quarshie WO, Zaoutis T, Mukhopadhyay S. Intrapartum Group B Streptococcal Prophylaxis and Childhood Allergic Disorders. Pediatrics. 2021 May;147(5):e2020012187. PMID: 33833072; PMCID: PMC8085997.

Dilollo J, Rodríguez-López EM, Wilkey L, Martin EK, Spergel JM, Hill DA Peripheral markers of allergen-specific immune activation predict clinical allergy in eosinophilic esophagitis.Allergy. 2021 Nov;76(11):3470-3478. doi: 10.1111/all.14854. Epub 2021 May 14. PMID: 33840099; PMCID: PMC8502783

Kennedy K, Alfaro MKC, Spergel ZC, Dorris SL, Spergel JM, Capucilli P. Differences in oral food challenge reaction severity based on increasing age in a pediatric population. Ann Allergy Asthma Immunol. 2021 May 16:S1081-1206(21)00360-4. PMID: 34010700.

Ma C, Schoepfer AM, Safroneeva E; COREOS Collaborators; COREOS Collaborators. Development of a Core Outcome Set for Therapeutic Studies in Eosinophilic Esophagitis (COREOS): An International Multidisciplinary Consensus. Gastroenterology. 2021 Sep;161(3):748-755. PMID: 34022180.

Safroneeva E, Pan Z, King E, Martin LJ, Collins MH, Yang GY, Capocelli KE, Arva NC, Abonia JP, Atkins D, Bonis PA, Dellon ES, Falk GW, Gonsalves N, Gupta SK, Hirano I, Leung J, Menard-Katcher PA, Mukkada VA, Schoepfe AM, Spergel JM, Wershil BK, Rothenberg ME, Aceves SS, Furuta GT; Consortium of Eosinophilic Gastrointestinal Disease Researchers. Long-Lasting Dissociation of Esophageal Eosinophilia and Symptoms Following Dilation in Adults With Eosinophilic Esophagitis. Clin Gastroenterol Hepatol. 2021 May 29:S1542-3565(21)00588-7. PMID: 34062314.

Arehart CH, Daya M, Campbell M, Boorgula MP, Rafaels N, Chavan S, David G, Hanifin J, Slifka MK, Gallo RL, Hata T, Schneider LC, Paller AS, Ong PY, Spergel JM, Guttman-Yassky E, Leung DYM, Beck LA, Gignoux CR, Mathias RA, Barnes KC. Polygenic prediction of atopic dermatitis improves with atopic training and filaggrin factors. . J Allergy Clin Immunol. 2022 Jan;149(1):145-155. doi: 10.1016/j.jaci.2021.05.034. Epub 2021 Jun 7. PMID: 34111454

Dahlsgaard KK, Wilkey LK, Stites SD, Lewis MO, Spergel JM. Development of the Child- and Parent-Rated Scales of Food Allergy Anxiety (SOFAA). J Allergy Clin Immunol Pract. 2022 Jan;10(1):161-169.e6. doi: 10.1016/j.jaip.2021.06.039. Epub 2021 Jul 12. PMID: 34265450.

Ruffner MA, Zhang Z, Maurer K, Muir AB, Cianferoni A, Sullivan KE, Spergel JM. RNA sequencing identifies global transcriptional changes in peripheral CD4+ cells during active oesophagitis and following epicutaneous immunotherapy in eosinophilic oesophagitis. Clin Transl Immunology. 2021 Jul 22;10(7):e1314. PMID: 34322233; PMCID: PMC8296633

Spergel JM, Blaiss MS, Lio P, Kessel A, Cantrell WC, Takiya L, Werth JL, O'Connell MA, Zang C, Cork MJ. Efficacy and safety of crisaborole in patients with mild-to-moderate atopic dermatitis and other atopic comorbidities. Allergy Asthma Proc. 2021 Sep 1;42(5):425-431. doi: 10.2500/aap.2021.42.210064. PMID:34474712.

Bégin P, Bird JA, Spergel JM, Campbell DE, Green TD, Bee KJ, Lambert R, Sampson HA, Fleischer DM. Reduction in peanut reaction severity during oral challenge after 12 months of epicutaneous immunotherapy. Allergy. 2021 Dec;76(12):3835-3838. doi: 10.1111/all.15083. Epub 2021 Sep 28. PMID: 34492123.

Daya M, Cox C, Acevedo N, Boorgula MP, Campbell M, Chavan S, Cho MH, David GL, Kachroo P, Lasky-Su J, Li X, McHugh CP, Qiao D, Rafaels N, Beck LA, Bleecker ER, Caraballo L, Cupples AL, Figueiredo CA, Gallo RL, Hanifin J, Hansel NN, Hata TR, Hersh CP, Knight-Madden J, Leung DYM, Guttman-Yassky E, Meyers DA, O'Connor G, Ober C, Ong PY, Ortega VE, Paller AS, Putcha N, Reed RM, Schneider LC, Silverman EK, Slifka MK, Spergel JM, Vasan RS, Viaud-Martinez KA, Watson H, Weiss ST; NHLBI Trans-Omics for Precision Medicine (TOPMed) Consortium, Ruczinski I, Beaty TH, Mathias RA, Barnes KC. Multi-ethnic genome-wide and HLA association study of total serum IgE. J Allergy Clin Immunol. 2021 Dec;148(6):1589-1595. doi: 10.1016/j.jaci.2021.09.011. Epub 2021 Sep 15. PMID: 34536413; PMCID: PMC8665111.

Holvoet S, Nutten S, Dupuis L, Donnicola D, Bourdeau T, Hughes-Formella B, Simon D, Simon HU, Carvalho RS, Spergel JM, Koletzko S, Blanchard C. Partially Hydrolysed Whey-Based Infant Formula Improves Skin Barrier Function. Nutrients. 2021 Sep 4;13(9):3113. PMID: 34578990; PMCID: PMC8472312

Chen G, Shrock EL, Li MZ, Spergel JM, Nadeau KC, Pongracic JA, Umetsu DT, Rachid R, MacGinnitie AJ, Phipatanakul W, Schneider L, Oettgen HC, Elledge SJ. High-resolution epitope mapping by AllerScan reveals relationships between IgE and IgG repertoires during peanut oral immunotherapy. Cell Rep Med. 2021 Oct 19;2(10):100410. doi: 10.1016/j.xcrm.2021.100410. PMID: 34755130; PMCID: PMC8563412

2020

Dunn JLM, Shoda T, Caldwell JM, Wen T, Aceves SS, Collins MH, Dellon ES, Falk GW, Leung J, Martin LJ, Menard-Katcher P, Rudman-Spergel A, Spergel JM, Wechsler JB, Yang GY, Furuta GT, Rothenberg ME; CEGIR Esophageal type 2 cytokine expression heterogeneity in eosinophilic esophagitis in a multi-site cohort. J Allergy Clin Immunol. 2020 145(6):1629-1640.e4. PMID: 32197970

Capucilli P, Wang KY, Spergel JM. Food reactions during avoidance: Focus on peanut. Ann Allergy Asthma Immunol. 2020 May;124(5):459-465. PMID: 32001367.

Dupuis R, Kinsey EW, Spergel JM, Brown-Whitehorn T, Graves A, Samuelson K, Epstein C, Mollen C, Cannuscio CC. Food Allergy Management at School. J Sch Health. 2020 May;90(5):395-406. PMID: 32124441

Nakagawa H, Kasagi Y, Karakasheva TA, Hara T, Aaron B, Shimonosono M, Kijima T, Giroux V, Bailey D, Wilkins B, Abrams JA, Falk GW, Aceves SS, Spergel JM, Hamilton KE, Whelan KA, Muir AB. Modeling Epithelial Homeostasis and Reactive Epithelial Changes in Human and Murine Three-Dimensional Esophageal Organoids. Curr Protoc Stem Cell Biol. 2020 Mar;52(1):e106. PMID: 32105412

Aceves S, Collins MH, Rothenberg ME, Furuta GT, Gonsalves N; Consortium of Eosinophilic Gastrointestinal Disease Researchers (CEGIR). Advancing patient care through the Consortium of Eosinophilic Gastrointestinal Disease Researchers (CEGIR). J Allergy Clin Immunol. 2020 Jan;145(1):28-37. PMID: 31758958

Dribin TE, Sampson HA, Camargo CA Jr, Brousseau DC, Spergel JM, Neuman MI, Shaker M, Campbell RL, Michelson KA, Rudders SA, Assa'ad AH, Risma KA, Castells M, Schneider LC, Wang J, Lee J, Mistry RD, Vyles D, Vaughn LM, Schumacher DJ, Witry JK, Viswanathan S, Page EM, Schnadower D. Persistent, refractory, and biphasic anaphylaxis: a multidisciplinary Delphi study.  J Allergy Clin Immunol. 2020 Nov;146(5):1089-1096.  PMID: 32853640; PMCID: PMC8006564.

Brown-Whitehorn T, de Blay F, Spergel JM, Green TD, Peillon A, Sampson HA, Campbell DE. Sustained Unresponsiveness to Peanut After Long-Term Peanut Epicutaneous Immunotherapy.  J Allergy Clin Immunol Pract. 2020 Aug 21:S2213-2198(20)30833-3. PMID: 32835872

Fleischer DM, Spergel JM, Kim EH, Campbell DE, Green TD, Bee KJ, Lambert R, Ocheltree T, Sampson HA. Evaluation of daily patch application duration for epicutaneous immunotherapy for peanut allergy.  Allergy Asthma Proc. 2020 Jul 1;41(4):278-284. PMID: 32517847

Dahlsgaard KK, Lewis MO, Spergel JM. New issue of food allergy: Phobia of anaphylaxis in pediatric patients.  J Allergy Clin Immunol. 2020 Jul 23:S0091-6749(20)31028-9. doi: 10.1016/j.jaci.2020.07.010. PMID: 32710976

Jensen ET, Aceves SS, Bonis PA, Bray K, Book W, Chehade M, Collins MH, Dellon ES, Falk GW, Gonsalves N, Gupta SK, Hirano I, Katzka DA, Kyle S, Mack D, Kodroff E, Leung J, Mukkada VA, Scott M, Paliana A, Sable K, Spergel JM, Strobel MJ, Krischer J, Rothenberg ME, Abonia JP; and the CEGIR Investigator group. High Patient Disease Burden in a Cross-Sectional, Multicenter Contact Registry Study of Eosinophilic Gastrointestinal Diseases.  J Pediatr Gastroenterol Nutr. 2020 Jun 11 PMID: 32541201

Whelan KA, Godwin BC, Wilkins B, Elci OU, Benitez A, DeMarshall M, Sharma M, Gross J, Klein-Szanto AJ, Liacouras CA, Dellon ES, Spergel JM, Falk GW, Muir AB,  Nakagawa H. Persistent Basal Cell Hyperplasia Is Associated With Clinical and Endoscopic Findings in Patients With Histologically Inactive Eosinophilic Esophagitis. Clin Gastroenterol Hepatol. 2 2020 Jun;18(7):1475-1482.e PubMed PMID: 31499251.

Mansbach JM, Hasegawa K, Geller RJ, Espinola JA, Sullivan AF, Camargo CA Jr; MARC-35 Investigators. Bronchiolitis severity is related to recurrent wheezing by age 3 years in a prospective, multicenter cohort. Pediatr Res. 2020 Feb;87(3):428-430. PMID: 31585458

Shoda T, Wen T, Caldwell JM, Collins MH, Besse JA, Osswald GA, Abonia JP, Arva NC, Atkins D, Capocelli KE, Dellon ES, Falk GW, Gonsalves N, Gupta SK, Hirano I,  Mukkada VA, Putnam PE, Sheridan RM, Spergel Ak R, Spergel JM, Wechsler JB, Yang GY, Aceves SS, Furuta GT, Rothenberg ME; Consortium of Eosinophilic Gastrointestinal Disease Researchers (CEGIR). Molecular, Endoscopic, Histologic and Circulating Biomarker-Based Diagnosis of Eosinophilic Gastritis: Multi-Site Study. J Allergy Clin Immunol. 2020 Jan;145(1):255-269. PMID: 31738990.

Ruffner MA, Wang KY, Dudley JW, Cianferoni A, Grundmeier RW, Spergel JM, Brown-Whitehorn TF, Hill DA. Elevated Atopic Comorbidity in Patients with Food Protein-Induced Enterocolitis. J Allergy Clin Immunol Pract. 2020 Mar;8(3):1039-1046. PubMed PMID: 31759160

2019

Kennedy K, Muir AB, Grossman A, Brown-Whitehorn T, Cianferoni A, Spergel JM, Furuta GT, Wilkins BJ, Shuker M, Ruffner MA. Modified oral enteric-coated budesonide regimens to treat pediatric eosinophilic gastroenteritis, a single center experience. J Allergy Clin Immunol Pract. 2019 Jul - Aug;7(6):2059-2061. PubMed PMID: 30763733.

Muir AB, Jensen ET, Wechsler JB, Menard-Katcher P, Falk GW, Aceves SS, Furuta GT, Dellon ES, Rothenberg ME, Spergel JM. Overestimation of the diagnosis of eosinophilic colitis with reliance on billing codes. J Allergy Clin Immunol Pract. 2019 Sep - Oct;7(7):2434-2436. PubMed PMID: 30922989.

Lewis MO, Brown-Whitehorn TF, Cianferoni A, Rooney C, Spergel JM. Peanut-allergic patient experiences after epicutaneous immunotherapy: peanut consumption and impact on QoL. Ann Allergy Asthma Immunol. 2019 Jul;123(1):101-103. PMID: 30978404.

Pesek RD, Reed CC, Muir AB, Fulkerson PC, Menard-Katcher C, Falk GW, Kuhl J,  Martin EK, Magier AZ, Ahmed F, Demarshall M, Gupta A, Gross J, Ashorobi T, Carpenter CL, Krischer JP, Gonsalves N, Spergel JM, Gupta SK, Furuta GT, Rothenberg ME, Dellon ES; Consortium of Eosinophilic Gastrointestinal Disease Researchers (CEGIR). Increasing Rates of Diagnosis, Substantial Co-Occurrence, and Variable Treatment Patterns of Eosinophilic Gastritis, Gastroenteritis, and Colitis Based on 10-Year Data Across a Multicenter Consortium. Am J Gastroenterol. 2019 Jun;114(6):984-994. PubMed PMID: 31008735; PubMed Central PMCID: PMC6554065

Spergel JM, Elci OU, Muir AB, Liacouras CA, Wilkins BJ, Burke D, Lewis MO, Brown-Whitehorn T, Cianferoni A. Efficacy of Epicutaneous Immunotherapy in Children With Milk-Induced Eosinophilic Esophagitis. Clin Gastroenterol Hepatol.  2020 Feb;18(2):328-336.e PubMed PMID: 31100455.

Andorf S, Purington N, Kumar D, Long A, O'Laughlin KL, Sicherer S, Sampson H,  Cianferoni A, Whitehorn TB, Petroni D, Makhija M, Robison RG, Lierl M, Logsdon S, Desai M, Galli SJ, Rael E, Assa'ad A, Chinthrajah S, Pongracic J, Spergel JM, Tam J, Tilles S, Wang J, Nadeau K. A Phase 2 Randomized Controlled Multisite Study Using Omalizumab-facilitated Rapid Desensitization to Test Continued vs Discontinued Dosing in Multifood Allergic Individuals. EClinicalMedicine. 2019 Jan 21;7:27-38. PubMed PMID: 31193674; PubMed Central PMCID: PMC6537534.

Ruffner MA, Song L, Maurer K, Shi L, Carroll MC, Wang JX, Muir AB, Spergel JM, Sullivan KE. Toll-like receptor 2 stimulation augments esophageal barrier integrity. Allergy. Dec;74(12):2449-2460. PubMed PMID: 31267532.

Klinnert MD, Atkins D, Pan Z, Franciosi JP, Aceves SS, Spergel JM, Furuta GT.  Symptom Burden and Quality of Life Over Time in Pediatric Eosinophilic Esophagitis. J Pediatr Gastroenterol Nutr. 2019 Dec;69(6):682-689.  PMID: 31436703.

Pesek RD, Reed CC, Collins MH, Muir AB, Fulkerson PC, Menard-Katcher C, Falk GW, Kuhl J, Magier AZ, Ahmed FN, Demarshall M, Gupta A, Gross J, Ashorobi T, Carpenter CL, Krischer JP, Gonsalves N, Hirano I, Spergel JM, Gupta SK, Furuta GT, Rothenberg ME, Dellon ES; Consortium of Eosinophilic Gastrointestinal Disease Researchers (CEGIR). Association Between Endoscopic and Histologic Findings in a  Multicenter Retrospective Cohort of Patients with Non-esophageal Eosinophilic Gastrointestinal Disorders. Dig Dis Sci. 2019 Nov 26. PubMed PMID: 31773359

Schoepfer AM, Hirano I, Coslovsky M, Roumet MC, Zwahlen M, Kuehni CE, Hafner  D, Alexander JA, Dellon ES, Gonsalves N, Leung J, Bussmann C, Collins MH, Newbury RO, Smyrk TC, Woosley JT, Yang GY, Romero Y, Katzka DA, Furuta GT, Gupta SK, Aceves SS, Chehade M, Spergel JM, Falk GW, Meltzer BA, Comer GM, Straumann A, Safroneeva E; International EEsAI Study Group. Variation in Endoscopic Activity Assessment and Endoscopy Score Validation in Adults with Eosinophilic Esophagitis. Clin Gastroenterol Hepatol.  2019 Jul; 17(8) 1477-1488. PubMed PMID 30476587

Stranks AJ, Minnicozzi SC, Miller SJ, Burton OT, Logsdon SL, Spergel JM, Nadeau KC, Pongracic JA, Umetsu DT, Rachid R, MacGinnitie AJ, Schneider LC, Oettgen HC. Immunoglobulin E blockade during food allergen ingestion enhances the induction of inhibitory immunoglobulin G antibodies. Ann Allergy Asthma Immunol.  2019 Feb;122(2):213-215. PubMed PMID: 30404033; PubMed Central PMCID: PMC6360101.

Capucilli P, Kennedy K, Kazatsky AM, Cianferoni A, Spergel JM. Fruit for thought: anaphylaxis to fruit pectin in foods. J Allergy Clin Immunol Pract. 2019 Feb;7(2):719-720. PubMed PMID: 30553053.

Capucilli P, Kennedy K, Lee J, Grundmeier RW, Spergel JM. Accidental versus new food allergy reactions in a pediatric emergency department. J Allergy Clin Immunol Pract. 2019 May - Jun;7(5):1662-1664. PubMed PMID: 30496829

Shaker M, Yuan I, Kennedy KL, Capucilli P, Spergel JM. Idiopathic anaphylaxis and undiagnosed anorexia nervosa. Ann Allergy Asthma Immunol. 2019 Feb;122(2):215-217. PubMed PMID: 30352289.

Wang KY, Lee J, Cianferoni A, Ruffner MA, Dean A, Molleston JM, Pawlowski NA, Heimall J, Saltzman RW, Ram GS, Fiedler J, Gober LM, Spergel JM, Brown-Whitehorn  TF. Food Protein-Induced Enterocolitis Syndrome Food Challenges: Experience from  a Large Referral Center. J Allergy Clin Immunol Pract. 2019 Feb;7(2):444-450. PubMed PMID: 30243880.

Kennedy K, Muir AB, Grossman A, Brown-Whitehorn T, Cianferoni A, Spergel JM, Furuta GT, Wilkins BJ, Shuker M, Ruffner MA. Modified oral enteric-coated budesonide regimens to treat pediatric eosinophilic gastroenteritis, a single center experience. J Allergy Clin Immunol Pract. 2019 Feb 11. pii: S2213-2198(19)30162-X. doi: 10.1016/j.jaip.2019.01.053. [Epub ahead of print] PubMed PMID: 30763733.

Muir AB, Jensen ET, Wechsler JB, Menard-Katcher P, Falk GW, Aceves SS, Furuta GT, Dellon ES, Rothenberg ME, Spergel JM. Overestimation of the diagnosis of eosinophilic colitis with reliance on billing codes. J Allergy Clin Immunol Pract. 2019 Mar 25. pii: S2213-2198(19)30284-3. doi: 10.1016/j.jaip.2019.03.020.  [Epub ahead of print] PubMed PMID: 30922989.

2018

Hill DA, Grundmeier RW, Ramos M, Spergel JM. Eosinophilic Esophagitis Is Late Manifestation of the Allergic March. J Allergy Clin Immunol Pract. 2018 Sep  - Oct;6(5):1528-1533. doi: 10.1016/j.jaip.2018.05.010. Epub 2018 Jun 25. PubMed PMID: 29954692; PubMed Central PMCID: PMC6131029. 10.1016/j.cgh.2018.11.032. [Epub ahead of print] PubMed PMID: 30476587.

Gupta SK, Falk GW, Aceves SS, Chehade M, Collins MH, Dellon ES, Gonsalves N,  Hirano I, Mukkuda VA, Peterson KA, Spergel J, Yang GY, Furuta GT, Rothenberg ME;  Consortium of Eosinophilic Gastrointestinal Disease Researchers (CEGIR). Consortium of Eosinophilic Gastrointestinal Disease Researchers: Advancing the Field of Eosinophilic GI Disorders Through Collaboration. Gastroenterology. 2019  Mar;156(4):838-842. doi: 10.1053/j.gastro.2018.10.057. Epub 2018 Nov 17. PubMed PMID: 30452923

PALISADE Group of Clinical Investigators, Vickery BP, Vereda A, Casale TB, Beyer K, du Toit G, Hourihane JO, Jones SM, Shreffler WG, Marcantonio A, Zawadzki R, Sher L, Carr WW, Fineman S, Greos L, Rachid R, Ibáñez MD, Tilles S, Assa’ad AH, Nilsson C, Rupp N, Welch MJ, Sussman G, Chinthrajah S, Blumchen K, Sher E, Spergel JM, Leickly FE, Zielen S, Wang J, Sanders GM, Wood RA, Cheema A, Bindslev-Jensen C, Leonard S, Kachru R, Johnston DT, Hampel FC Jr, Kim EH Anagnostou A, Pongracic JA, Ben-Shoshan M, Sharma HP, Stillerman A, Windom HH, Yang WH, Muraro A, Zubeldia JM, Sharma V, Dorsey MJ, Chong HJ, Ohayon J, Bird JA, Carr TF, Siri D, Fernández-Rivas M, Jeong DK, Fleischer DM, Lieberman JA, Dubois  AEJ, Tsoumani M, Ciaccio CE, Portnoy JM, Mansfield LE, Fritz SB, Lanser BJ, Matz J, Oude Elberink HNG, Varshney P, Dilly SG, Adelman DC, Burks AW. AR101 Oral Immunotherapy for Peanut Allergy. N Engl J Med. 2018 Nov 22;379(21):1991-2001. PubMed PMID: 30449234.

Kasagi Y, Dods K, Wang JX, Chandramouleeswaran PM, Benitez AJ, Gambanga F, Kluger J, Ashorobi T, Gross J, Tobias JW, Klein-Szanto AJ, Spergel JM, Cianferoni A, Falk GW, Whelan KA, Nakagawa H, Muir AB. Fibrostenotic eosinophilic esophagitis might reflect epithelial lysyl oxidase induction by fibroblast-derived TNF-α. J Allergy Clin Immunol. 2019 Jul;144(1):171-182 PubMed PMID: 30578874; PubMed Central PMCID: PMC6586527.

Godwin B, Liacouras C, Mehta V, Eisenberg J, Agawu A, Brown-Whitehorn T, Ruffner MA, Verma R, Cianferoni A, Spergel JM, Muir AB. A Review of Tertiary Referrals for Management of Pediatric Esophageal Eosinophilia. Front Pediatr. 2018 Jun 20;6:173. doi: 10.3389/fped.2018.00173. eCollection 2018. PubMed PMID:29974044; PubMed Central PMCID: PMC6019483

Purington N, Chinthrajah RS, Long A, Sindher S, Andorf S, O'Laughlin K, Woch MA, Scheiber A, Assa'ad A, Pongracic J, Spergel JM, Tam J, Tilles S, Wang J, Galli SJ, Desai M, Nadeau KC. Eliciting Dose and Safety Outcomes From a Large Dataset of Standardized Multiple Food Challenges. Front Immunol. 2018 Sep 21;9:2057. PubMed PMID: 30298065; PubMed Central PMCID: PMC6160556.

6Leigh LY, Spergel JM. An in-depth characterization of a large cohort of adult patients with eosinophilic esophagitis. Ann Allergy Asthma Immunol. 2019 Jan;122(1):65-72.e1. PubMed PMID: 30223114.

Capucilli P, Cianferoni A, Grundmeier RW, Spergel JM. Comparison of comorbid diagnoses in children with and without eosinophilic esophagitis in a large population. Ann Allergy Asthma Immunol. 2018 Dec;121(6):711-716. PubMed PMID: 30194971.

Ruffner MA, Henrickson SE, Chilutti M, Grundmeier R, Spergel JM, Brown-Whitehorn TF. Improving allergy office scheduling increases patient follow  up and reduces asthma readmission after pediatric asthma hospitalization. Ann Allergy Asthma Immunol. 2018 Nov;121(5):561-567. PubMed PMID: 30170026; PubMed Central PMCID: PMC6236684.

Capucilli P, Cianferoni A, Fiedler J, Gober L, Pawlowski N, Ram G, Saltzman R, Spergel JM, Heimall J. Differences in egg and milk food challenge outcomes based on tolerance to the baked form. Ann Allergy Asthma Immunol. 2018 Nov;121(5):580-587. PubMed PMID: 30036581.

Warren CM, Zaslavsky JM, Kan K, Spergel JM, Gupta RS. Epinephrine auto-injector carriage and use practices among US children, adolescents, and adults. Ann Allergy Asthma Immunol. 2018 Oct;121(4):479-491. doi: 10.1016/j.anai.2018.06.010. Epub 2018 Jun 21. PubMed PMID: 29936229.

Sindher S, Long AJ, Purington N, Chollet M, Slatkin S, Andorf S, Tupa D, Kumar D, Woch MA, O'Laughlin KL, Assaad A, Pongracic J, Spergel JM, Tam J, Tilles S, Wang J, Galli SJ, Nadeau KC, Chinthrajah RS. Analysis of a Large Standardized Food Challenge Data Set to Determine Predictors of Positive Outcome Across Multiple Allergens. Front Immunol. 2018 Nov 27;9:2689. doi: 10.3389/fimmu.2018.02689. eCollection 2018. PubMed PMID: 30538699; PubMed Central PMCID: PMC6277531.

Hiremath G, Kodroff E, Strobel MJ, Scott M, Book W, Reidy C, Kyle S, Mack D,  Sable K, Abonia P, Spergel J, Gupta SK, Furuta TG, Rothenberg ME, Dellon ES. Individuals affected by eosinophilic gastrointestinal disorders have complex unmet needs and frequently experience unique barriers to care. Clin Res Hepatol Gastroenterol. 2018 Oct;42(5):483-493. Epub 2018 Mar 31. PubMed PMID: 29615329; PubMed Central PMCID: PMC6167209

Fahey LM, Guzek R, Ruffner MA, Sullivan KE, Spergel J, Cianferoni A. EMSY is increased and activates TSLP & CCL5 expression in eosinophilic esophagitis. Pediatr Allergy Immunol. 2018 Aug;29(5):565-568. doi: 10.1111/pai.12907. Epub 2018 May 29. PubMed PMID: 29663593.

Shoda T, Wen T, Aceves SS, Abonia JP, Atkins D, Bonis PA, Caldwell JM, Capocelli KE, Carpenter CL, Collins MH, Dellon ES, Eby MD, Gonsalves N, Gupta SK, Falk GW, Hirano I, Menard-Katcher P, Kuhl JT, Krischer JP, Leung J, Mukkada VA, Spergel JM, Trimarchi MP, Yang GY, Zimmermann N, Furuta GT, Rothenberg ME; Consortium of Eosinophilic Gastrointestinal Disease Researchers (CEGIR). Eosinophilic oesophagitis endotype classification by molecular, clinical, and histopathological analyses: a cross-sectional study. Lancet Gastroentero Hepatol. 2018 Jul;3(7):477-488. doi: 10.1016/S2468-1253(18)30096-7. Epub 2018 May PubMed PMID: 29730081; PubMed Central PMCID: PMC5997568.

Hasegawa K, Piedra PA, Bauer CS, Celedón JC, Mansbach JM, Spergel JM, Espinola JA, Camargo CA Jr; MARC-35 Investigators. Nasopharyngeal CCL5 in infants with severe bronchiolitis and risk of recurrent wheezing: A multi-center prospective cohort study. Clin Exp Allergy. 2018 Aug;48(8):1063-1067. doi: 10.1111/cea.13166. Epub 2018 Jun 4. PubMed PMID: 29756403; PubMed Central PMCID:  PMC6105518.

Aceves SS, King E, Collins MH, Yang GY, Capocelli KE, Abonia JP, Atkins D, Bonis PA, Carpenter CL, Dellon ES, Eby MD, Falk GW, Gonsalves N, Gupta SK, Hirano I, Kocher K, Krischer JP, Leung J, Lipscomb J, Menard-Katcher P, Mukkada VA, Pan  Z, Spergel JM, Sun Q, Wershil BK, Rothenberg ME, Furuta GT; Consortium of Eosinophilic Gastrointestinal Disease Researchers (CEGIR). Alignment of parent- and child-reported outcomes and histology in eosinophilic esophagitis across multiple CEGIR sites. J Allergy Clin Immunol. 2018 Jul;142(1):130-138.e1. doi: 10.1016/j.jaci.2018.05.014. Epub 2018 May 29. PubMed PMID: 29852258; PubMedCentral PMCID: PMC6035777.

Ma C, van Rhijn BD, Jairath V, Nguyen TM, Parker CE, Aceves SS, Furuta GT, Gupta SK, Katzka DA, Safroneeva E, Schoepfer AM, Straumann A, Spergel JM, Pai RK, Feagan BG, Hirano I, Dellon ES, Bredenoord AJ. Heterogeneity in Clinical, Endoscopic, and Histologic Outcome Measures and Placebo Response Rates in Clinical Trials of Eosinophilic Esophagitis: A Systematic Review. Clin Gastroenterol Hepatol. 2018 Nov;16(11):1714-1729.e3. doi: 10.1016/j.cgh.2018.06.005. Epub 2018 Jun 14. Review. PubMed PMID: 29908360.

Petroni D, Spergel JM. Eosinophilic esophagitis and symptoms possibly related to eosinophilic esophagitis in oral immunotherapy. Ann Allergy Asthma Immunol. 2018 120(3):237-240. PMID: 29397272

Fahey LM, Chandramouleeswaran PM, Guan S, Benitez AJ, Furuta GT, Aceves SS, Wang ML, Liacouras CA, Muir AB, Sleiman PM, Hakonarson H, Spergel JM, Cianferoni A. Food allergen triggers are increased in children with the TSLP risk allele and eosinophilic esophagitis. Clin Transl Gastroenterol. 2018 Mar 6;9(3):139. PubMed PMID: 29511165; PubMed Central PMCID: PMC5862152.

Kasagi Y, Chandramouleeswaran PM, Whelan KA, Tanaka K, Giroux V, Sharma M, Wang J, Benitez AJ, DeMarshall M, Tobias JW, Hamilton KE, Falk GW, Spergel JM, Klein-Szanto AJ, Rustgi AK, Muir AB, Nakagawa H. The Esophageal Organoid System Reveals Functional Interplay Between Notch and Cytokines in Reactive Epithelial Changes. Cell Mol Gastroenterol Hepatol. 2018 Jan 3;5(3):333-352. PubMed PMID: 29552622; PubMed Central PMCID: PMC5852293.

Shoda T, Wen T, Aceves SS, Abonia JP, Atkins D, Bonis PA, Caldwell JM, Capocelli KE, Carpenter CL, Collins MH, Dellon ES, Eby MD, Gonsalves N, Gupta SK, Falk GW, Hirano I, Menard-Katcher P, Kuhl JT, Krischer JP, Leung J, Mukkada VA, Spergel JM, Trimarchi MP, Yang GY, Zimmermann N, Furuta GT, Rothenberg ME;Consortium of Eosinophilic Gastrointestinal Disease Researchers (CEGIR). Eosinophilic oesophagitis endotype classification by molecular, clinical, and histopathological analyses: a cross-sectional study. Lancet Gastroenterol Hepatol. 2018 Jul;3(7):477-488 PubMed PMID: 29730081; PubMed Central PMCID: PMC5997568.

Fahey LM, Guzek R, Ruffner MA, Sullivan KE, Spergel J, Cianferoni A. EMSY is  increased and activates TSLP & CCL5 expression in eosinophilic esophagitis. Pediatr Allergy Immunol. 2018 Aug;29(5):565-568.  PubMed PMID: 29663593

Lee J, Rodio B, Lavelle J, Lewis MO, English R, Hadley S, Molnar J, Jacobstein C, Cianferoni A, Spergel J, Zielinski L, Tsarouhas N, Brown-Whitehorn  T. Improving Anaphylaxis Care: The Impact of a Clinical Pathway. Pediatrics. 2018 May;141(5). PubMed PMID: 29615480.

Shaker M, Stukus D, Chan ES, Fleischer DM, Spergel JM, Greenhawt M. "To screen or not to screen": Comparing the health and economic benefits of early peanut introduction strategies in five countries. Allergy. 2018. Aug;73(8):1707-1714.  Epub 2018 May 24. PubMed PMID: 29601091

Hiremath G, Kodroff E, Strobel MJ, Scott M, Book W, Reidy C, Kyle S, Mack D,  Sable K, Abonia P, Spergel J, Gupta SK, Furuta TG, Rothenberg ME, Dellon ES. Individuals affected by eosinophilic gastrointestinal disorders have complex unmet needs and frequently experience unique barriers to care. Clin Res Hepatol Gastroenterol. 2018 Oct;42(5):483-493. PubMed PMID: 29615329; PubMed Central PMCID: PMC6167209

Sauser J, Nutten S, de Groot N, Pecquet S, Simon D, Simon HU, Spergel JM, Koletzko S, Blanchard C.  Partially Hydrolyzed Whey Infant Formula: Literature Review on Effects on Growth and the Risk of Developing Atopic Dermatitis in Infants from the General Population. Int Arch Allergy Immunol. 2018 Jul 12:1-12. PMID: 30001534

Hasegawa K, Piedra PA, Bauer CS, Celedón JC, Mansbach JM, Spergel JM, Espinola JA, Camargo CA Jr; MARC-35 Investigators. Nasopharyngeal CCL5 in infants with severe bronchiolitis and risk of recurrent wheezing: A multi-center prospective cohort study. Clin Exp Allergy. 2018 Aug;48(8):1063-1067. PubMed PMID: 29756403; PubMed Central PMCID:  PMC6105518.

Hill DA, Grundmeier RW, Ramos M, Spergel JM. Eosinophilic Esophagitis Is a Late Manifestation of the Allergic March. J Allergy Clin Immunol Pract. 2018 6(5):1528-1533PubMed PMID: 29954692. PubMed Central PMCID: PMC6131029.

Warren CM, Zaslavsky JM, Kan K, Spergel JM, Gupta RS. Epinephrine auto-injector carriage and use practices among US children, adolescents, and adults. Ann Allergy Asthma Immunol. 2018 121(4):479-491. PubMed PMID: 29936229.

Ma C, van Rhijn BD, Jairath V, Nguyen TM, Parker CE, Aceves SS, Furuta GT, Gupta SK, Katzka DA, Safroneeva E, Schoepfer AM, Straumann A, Spergel JM, Pai RK, Feagan BG, Hirano I, Dellon ES, Bredenoord AJ. Heterogeneity in Clinical, Endoscopic, and Histologic Outcome Measures and Placebo Response Rates in Clinical Trials of Eosinophilic Esophagitis: A Systematic Review. Clin Gastroenterol Hepatol. 2018 Nov;16(11):1714-1729 Review. PubMed PMID: 29908360.

Aceves SS, King E, Collins MH, Yang GY, Capocelli KE, Abonia JP, Atkins D, Bonis PA, Carpenter CL, Dellon ES, Eby MD, Falk GW, Gonsalves N, Gupta SK, Hirano I, Kocher K, Krischer JP, Leung J, Lipscomb J, Menard-Katcher P, Mukkada VA, Pan Z, Spergel JM, Sun Q, Wershil BK, Rothenberg ME, Furuta GT; Consortium of Eosinophilic Gastrointestinal Disease Researchers (CEGIR). Alignment of parent- and child-reported outcomes and histology in eosinophilic esophagitis across multiple CEGIR sites. J Allergy Clin Immunol. 2018 Jul;142(1):130-138. PubMed PMID: 29852258; PubMed Central PMCID: PMC6035777

Godwin B, Liacouras C, Mehta V, Eisenberg J, Agawu A, Brown-Whitehorn T, Ruffner MA, Verma R, Cianferoni A, Spergel JM, Muir AB. A Review of Tertiary Referrals for Management of Pediatric Esophageal Eosinophilia. Front Pediatr. 2018 Jun 20;6:173. doi: 10.3389/fped.2018.00173. eCollection 2018. PubMed PMID: 29974044; PubMed Central PMCID: PMC6019483

Shaker M, Stukus D, Chan ES, Fleischer DM, Spergel JM, Greenhawt M. "To screen or not to screen": Comparing the health and economic benefits of early peanut introduction strategies in five countries. Allergy. 2018Aug;73(8):1707-1714. doi: 10.1111/all.13446. Epub 2018 May 24. PubMed PMID:2960109
 

2017

Hill DA, Leahy AB, Sciasci J, O'Neill SP, Reilly A, Balamuth N, Spergel JM, et al. Reply to: Medication contaminants as a potential  cause of anaphylaxis to vincristine: What about drug specific antigens? Pediatr Blood Cancer. 2018 Feb;65(2). doi: 10.1002/pbc.26868. Epub 2017 Oct 19. PubMed PMID: 29049863; PubMed Central PMCID: PMC5739934.

Mondoulet L, Kalach N, Dhelft V, Larcher T, Delayre-Orthez C, Spergel JM, et al. Treatment of gastric eosinophilia by epicutaneous immunotherapy in piglets sensitized to peanuts. Clin Exp Allergy. 2017 Dec;47(12):1640-1647. doi: 10.1111/cea.13037. Epub 2017 Oct 20. PubMed PMID: 28960628.

Davis DM, Borok J, Udkoff J, Lio P, Spergel J. Atopic dermatitis: phototherapy and systemic therapy. Semin Cutan Med Surg. 2017 Sep;36(3):118-123. doi: 10.12788/j.sder.2017.027. PubMed PMID: 28895958.

Ahluwalia J, Davis DM, Jacob S, Waldman A, Ong PY, Spergel JM, et al. Atopic dermatitis: addressing allergy, infection, itch and complementary therapies. Semin Cutan Med  Surg. 2017 Sep;36(3):112-117. doi: 10.12788/j.sder.2017.038. PubMed PMID: 28895957.

Davis DM, Waldman A, Jacob S, LeBovidge J, Ahluwalia J, Spergel JM, et al. Diagnosis, comorbidity, and psychosocial impact of atopic dermatitis. Semin Cutan Med Surg. 2017 Sep;36(3):95-99. doi: 10.12788/j.sder.2017.028. PubMed PMID: 28895954.

Eichenfield LF, Ahluwalia J, Davis DM, Fleischer DM, Waldman A, Spergel J. Curriculum United for Better Eczema Care: why, how, and what? Semin Cutan Med Surg. 2017 Sep;36(3):93-94. doi: 10.12788/j.sder.2017.033. PubMed PMID: 28895953.

Hill DA, Leahy AB, Sciasci J, O'Neill SP, Reilly A, Spergel JM, et al. Medication contaminants as a potential cause of anaphylaxis to vincristine. Pediatr Blood Cancer. 2018 Jan;65(1). doi: 10.1002/pbc.26761. Epub 2017 Aug 22. PubMed PMID: 28834048; PubMed Central PMCID: PMC5978699.

Ruffner MA, Brown-Whitehorn TF, Verma R, Cianferoni A, Gober L, Spergel JM, et al. Clinical tolerance in eosinophilic esophagitis. J Allergy Clin Immunol Pract. 2018 Mar - Apr;6(2):661-663. doi: 10.1016/j.jaip.2017.06.035. Epub 2017 Aug 12. PubMed PMID: 28811175; PubMed Central PMCID: PMC5809321.

Nowak-Wegrzyn A, Spergel JM. Food protein-induced enterocolitis syndrome: Not so rare after all! J Allergy Clin Immunol. 2017 Nov;140(5):1275-1276. doi: 10.1016/j.jaci.2017.07.020. Epub 2017 Aug 7. PubMed PMID: 28797735.

Cianferoni A, Saltzman R, Saretta F, Barni S, Dudek E, Kelleher M, Spergel JM. Invariant natural killer cells change after an oral allergy desensitization protocol for cow's milk. Clin Exp Allergy. 2017 Nov;47(11):1390-1397. doi: 10.1111/cea.12975. Epub 2017 Aug 23. PubMed PMID: 28685970.

Heimall J, Spergel JM. New pathways for itching in patients with atopic dermatitis? J Allergy Clin Immunol. 2017 Aug;140(2):393-394. doi: 10.1016/j.jaci.2017.06.004. Epub 2017 Jun 23. PubMed PMID: 28652154.
Menard-Katcher C, Benitez AJ, Pan Z, Ahmed FN, Wilkins BJ, Spergel JM, et al. Influence of Age and Eosinophilic Esophagitis on Esophageal Distensibility in a Pediatric Cohort. Am J Gastroenterol. 2017 Sep;112(9):1466-1473. doi: 10.1038/ajg.2017.131. Epub 2017 May 16. PubMed PMID: 28508868; PubMed Central PMCID: PMC5601317.

Togias A, Cooper SF, Acebal ML, Assa'ad A, Baker JR Jr, Spergel JM, et al. Addendum Guidelines for the Prevention  of Peanut Allergy in the United States: Summary of the National Institute of Allergy and Infectious Diseases-Sponsored Expert Panel. J Acad Nutr Diet. 2017 May;117(5):788-793. doi: 10.1016/j.jand.2017.03.004. PubMed PMID: 28449793.

Nowak-Węgrzyn A, Chehade M, Groetch ME, Spergel JM, Wood RA, et al. International  consensus guidelines for the diagnosis and management of food protein-induced enterocolitis syndrome: Executive Summary-Workgroup Report of the Adverse Reactions to Foods Committee, American Academy of Allergy, Asthma & Immunology. J Allergy Clin Immunol. 2017 Apr;139(4):1111-1126.e4. doi: 10.1016/j.jaci.2016.12.966. Epub 2017 Feb 4. PubMed PMID: 28167094.

Togias A, Cooper SF, Acebal ML, Assaʼad A, Baker JR Jr, Spergel JM, et al. Addendum guidelines for the prevention of peanut allergy in the United States. JAAPA. 2017 Mar;30(3):1-5. doi: 10.1097/01.JAA.0000512231.15808.66. PubMed PMID: 28151739.

Togias A, Cooper SF, Acebal ML, Assa'ad A, Baker JR Jr, Spergel JM, et al. Addendum Guidelines for the Prevention of Peanut Allergy in the United States: Report of the National Institute of Allergy and Infectious Diseases-Sponsored Expert Panel. J Pediatr Nurs. 2017 Jan - Feb;32:91-98. doi: 10.1016/j.pedn.2016.12.006. PubMed PMID: 28137368.

Togias A, Cooper SF, Acebal ML, Assa'ad A, Baker JR Jr, Spergel JM, et al. Addendum guidelines for the prevention of peanut allergy in the United States: Report of the National Institute of Allergy and Infectious Diseases-sponsored expert panel. Ann Allergy Asthma Immunol. 2017 Feb;118(2):166-173.e7. doi: 10.1016/j.anai.2016.10.004. Epub 2017 Jan 5. PubMed PMID: 28065802.

Togias A, Cooper SF, Acebal ML, Assa'ad A, Baker JR Jr, Spergel JM, et al. Addendum guidelines for the prevention of peanut allergy in the United States: Report of the National Institute of Allergy and Infectious Diseases-sponsored expert panel. J Allergy Clin Immunol. 2017 Jan;139(1):29-44. doi: 10.1016/j.jaci.2016.10.010. PubMed PMID: 28065278; PubMed Central PMCID: PMC5226648. (Published in 6 journals)

Togias A, Cooper SF, Acebal ML, Assa'ad A, Baker JR Jr, Spergel JM, et al. Addendum Guidelines for the Prevention of Peanut Allergy in the United States: Report of the National Institute of Allergy and Infectious Diseases-Sponsored Expert Panel. Pediatr Dermatol. 2017 Jan;34(1):e1-e21. doi: 10.1111/pde.13093. PubMed PMID: 28054723.

Togias A, Cooper SF, Acebal ML, Assa'ad A, Baker JR Jr, Spergel JM, et al. Addendum guidelines for the prevention of peanut allergy in the United States: Summary of the National Institute of Allergy and Infectious Diseases-sponsored expert panel. Pediatr Dermatol. 2017 Jan;34(1):5-12. doi: 10.1111/pde.13092. PubMed PMID: 28054718.

Hill DA, Dudley JW, Spergel JM. The Prevalence of Eosinophilic Esophagitis in Pediatric Patients with IgE-Mediated Food Allergy. J Allergy Clin Immunol Pract.  2017 Mar - Apr;5(2):369-375. doi: 10.1016/j.jaip.2016.11.020. Epub 2016 Dec 30. PubMed PMID: 28042003; PubMed Central PMCID: PMC5346349.

Greenhawt M, Fleischer DM, Chan ES, Venter C, Stukus D, Gupta R, Spergel JM. LEAPing through the looking glass: secondary analysis of the effect of skin test size and age of introduction on peanut tolerance after early peanut introduction. Allergy. 2017 Aug;72(8):1254-1260. doi: 10.1111/all.13100. Epub 2017 Mar 22. PubMed PMID: 27896827; PubMed Central PMCID: PMC5447487.

2016

MacGinnitie AJ, Rachid R, Gragg H, Little SV, Lakin P, Spergel JM, et al. Omalizumab facilitates rapid oral desensitization for peanut allergy. J Allergy Clin Immunol. 2017 Mar;139(3):873-881.e8. doi: 10.1016/j.jaci.2016.08.010. Epub 2016 Sep 5. PubMed PMID: 27609658; PubMed Central PMCID: PMC5369605.

Hill DA, Grundmeier RW, Ram G, Spergel JM. The epidemiologic characteristics  of healthcare provider-diagnosed eczema, asthma, allergic rhinitis, and food allergy in children: a retrospective cohort study. BMC Pediatr. 2016 Aug 20;16:133. doi: 10.1186/s12887-016-0673-z. PubMed PMID: 27542726; PubMed Central PMCID: PMC4992234.

Muir AB, Wang ML, Metz D, Falk G, Markowitz J, Spergel JM, Liacouras CA. Proton pump inhibitor-responsive oesophageal eosinophilia: too early to change clinical practice. Gut. 2017 May;66(5):979-980. doi: 10.1136/gutjnl-2016-312601. Epub 2016 Jul 26. PubMed PMID: 27464706; PubMed Central PMCID: PMC5568693.

Tuttle KL, Schneider TR, Henrickson SE, Morris D, Abonia JP, Spergel JM, Laidlaw TM. Aspirin-exacerbated respiratory disease: not always "adult-onset". J Allergy Clin Immunol Pract. 2016 Jul-Aug;4(4):756-8. doi: 10.1016/j.jaip.2016.05.016. PubMed PMID: 27393784; PubMed Central PMCID: PMC5461917.

Schneider L, Hanifin J, Boguniewicz M, Eichenfield LF, Spergel JM, Dakovic R, Paller AS. Study of the Atopic March: Development of Atopic Comorbidities. Pediatr Dermatol. 2016 Jul;33(4):388-98. doi: 10.1111/pde.12867. Epub 2016 Jun 7. PubMed PMID: 27273433; PubMed Central PMCID: PMC5649252.

Greenhawt M, Fleischer DM, Spergel JM. Is It Time for a Randomized Trial on Early Introduction of Milk? J Allergy Clin Immunol Pract. 2016 May-Jun;4(3):489-90. doi: 10.1016/j.jaip.2016.03.013. PubMed PMID: 27157938.

Lee J, Shuker M, Brown-Whitehorn T, Cianferoni A, Gober L, Spergel JM, et al. Oral viscous budesonide can be successfully delivered through a variety of vehicles to treat eosinophilic esophagitis in children. J Allergy Clin Immunol Pract. 2016 Jul-Aug;4(4):767-8. doi: 10.1016/j.jaip.2016.02.005. Epub 2016 Mar 26. PubMed PMID: 27025298.

Chandramouleeswaran PM, Shen D, Lee AJ, Benitez A, Dods K, Spergel JM, et al. Preferential Secretion of Thymic Stromal Lymphopoietin (TSLP) by Terminally Differentiated Esophageal Epithelial Cells: Relevance to Eosinophilic Esophagitis (EoE). PLoS One. 2016 Mar 18;11(3):e0150968. doi: 10.1371/journal.pone.0150968. eCollection 2016. PubMed PMID: 26992000; PubMed Central PMCID: PMC4798725.

Whelan KA, Merves JF, Giroux V, Tanaka K, Guo A, Spergel JM, et al. Autophagy mediates epithelial cytoprotection in eosinophilic oesophagitis. Gut. 2017 Jul;66(7):1197-1207. doi: 10.1136/gutjnl-2015-310341. Epub 2016 Feb 16. PubMed PMID: 26884425; PubMed Central PMCID: PMC4987278.

Merves JF, Whelan KA, Benitez AJ, Muir AB, Furuta GT, Spergel JM, et al. ATG7 Gene Expression as a Novel Tissue Biomarker in Eosinophilic Esophagitis. Am J Gastroenterol. 2016 Jan;111(1):151-3. doi: 10.1038/ajg.2015.404. PubMed PMID: 26785669; PubMed Central PMCID: PMC4725062.

Muir AB, Dods K, Henry SJ, Benitez AJ, Lee D, Spergel JM, et al. Eosinophilic Esophagitis-Associated Chemical and Mechanical Microenvironment Shapes Esophageal Fibroblast Behavior. J Pediatr Gastroenterol Nutr. 2016 Aug;63(2):200-9. doi: 10.1097/MPG.0000000000001100. PubMed PMID: 26727658; PubMed Central PMCID: PMC4929044.

Kliewer KL, Venter C, Cassin AM, Abonia JP, Aceves SS, Spergel JM, et al. Should wheat, barley, rye, and/or gluten be avoided in a 6-food elimination diet? J Allergy Clin Immunol. 2016 Apr;137(4):1011-1014. doi: 10.1016/j.jaci.2015.10.040. Epub 2015 Dec 24. PubMed PMID: 26725190; PubMed Central PMCID: PMC4826834.

2015

Spergel JM, Boguniewicz M, Schneider L, Hanifin JM, Paller AS, Eichenfield LF. Food Allergy in Infants With Atopic Dermatitis: Limitations of Food-Specific  IgE Measurements. Pediatrics. 2015 Dec;136(6):e1530-8. doi: 10.1542/peds.2015-1444. PubMed PMID: 26598458.

Safroneeva E, Straumann A, Coslovsky M, Zwahlen M, Kuehni CE, Spergel JM, et al. Symptoms Have Modest Accuracy in Detecting Endoscopic and Histologic Remission in Adults With Eosinophilic Esophagitis. Gastroenterology. 2016 Mar;150(3):581-590.e4. doi: 10.1053/j.gastro.2015.11.004. Epub 2015 Nov 14. PubMed PMID: 26584601; PubMed Central PMCID: PMC6011000.

Katz Y, Nowak-Węgrzyn A, Spergel JM. Prevalence of biphasic response in anaphylaxis due to purposeful administration of allergenic food. Ann Allergy Asthma Immunol. 2015 Dec;115(6):526-7. doi: 10.1016/j.anai.2015.09.002. Epub 2015 Oct 1. PubMed PMID: 26427969.

Fleischer DM, Sicherer S, Greenhawt M, Campbell D, Chan E, Spergel JM, et al. Consensus Communication on Early Peanut Introduction and Prevention of Peanut Allergy in High-Risk Infants. Pediatr Dermatol. 2016 Jan-Feb;33(1):103-6. doi: 10.1111/pde.12685. Epub 2015 Sep 10. PubMed PMID: 26354148.

Ram G, Cianferoni A, Spergel JM. Food allergy to uncommonly challenged foods is rare based on oral food challenge. J Allergy Clin Immunol Pract. 2016 Jan-Feb;4(1):156-7.e5. doi: 10.1016/j.jaip.2015.07.017. Epub 2015 Sep 3. PubMed PMID: 26342742.

Primary contributors, Fleischer DM, Sicherer S, Greenhawt M, Campbell D, Chan
E, Spergel JM, et al. Consensus Communication on Early Peanut Introduction and the Prevention of Peanut Allergy in High-risk Infants. Pediatrics. 2015 Aug 31. pii: peds.2015-2394. [Epub ahead of print] PubMed PMID: 26324871.

Cianferoni A, Spergel JM. From genetics to treatment of eosinophilic esophagitis. Curr Opin Allergy Clin Immunol. 2015 Oct;15(5):417-25. doi: 10.1097/ACI.0000000000000200. PubMed PMID: 26258919; PubMed Central PMCID: PMC4910818.

Ram G, Lee J, Ott M, Brown-Whitehorn TF, Cianferoni A, Spergel JM, et al. Seasonal exacerbation of esophageal eosinophilia in children with eosinophilic esophagitis and allergic rhinitis. Ann Allergy Asthma Immunol. 2015 Sep;115(3):224-228.e1. doi: 10.1016/j.anai.2015.07.004. Epub 2015 Jul 30. PubMed PMID: 26235409.

Li J, Fung I, Glessner JT, Pandey R, Wei Z, Spergel JM, et al. Copy Number Variations in CTNNA3 and RBFOX1 Associate with Pediatric Food Allergy. J Immunol. 2015 Aug 15;195(4):1599-607. doi: 10.4049/jimmunol.1402310. Epub 2015 Jul 17. PubMed PMID: 26188062.

Fleischer DM, Sicherer S, Greenhawt M, Campbell D, Chan E, Spergel JM, et al. Consensus communication on early peanut introduction and the prevention of peanut allergy in high-risk infants. Allergy. 2015 Oct;70(10):1193-5. doi: 10.1111/all.12687. PubMed PMID: 26148305.

Fleischer DM, Sicherer S, Greenhawt M, Campbell D, Chan E, Spergel JM, et al. Consensus communication on early peanut introduction and the prevention of peanut allergy in high-risk infants. Ann Allergy Asthma Immunol. 2015 Aug;115(2):87-90. doi: 10.1016/j.anai.2015.06.001. Epub 2015 Jun 27. PubMed PMID: 26122934.

Fleischer DM, Sicherer S, Greenhawt M, Campbell D, Chan E, Spergel JM, et al. Consensus communication on early peanut introduction and the prevention of peanut allergy in high-risk infants. J Allergy Clin Immunol. 2015 Aug;136(2):258-61. doi: 10.1016/j.jaci.2015.06.001. Epub 2015 Jun 20. Erratum in: J Allergy Clin Immunol. 2015 Dec;136(6):1710. PubMed PMID: 26100082. (Published in 6 journals)

Benitez AJ, Hoffmann C, Muir AB, Dods KK, Spergel JM, Bushman FD, Wang ML. Inflammation-associated microbiota in pediatric eosinophilic esophagitis. Microbiome. 2015 Jun 1;3:23. doi: 10.1186/s40168-015-0085-6. eCollection 2015. PubMed PMID: 26034601; PubMed Central PMCID: PMC4450515.

Merves J, Chandramouleeswaran PM, Benitez AJ, Muir AB, Lee AJ, Spergel JM, et al. Altered esophageal histamine receptor expression in Eosinophilic Esophagitis (EoE): implications on disease pathogenesis. PLoS One. 2015 Feb 27;10(2):e0114831. doi: 10.1371/journal.pone.0114831. eCollection 2015. PubMed PMID: 25723478; PubMed Central PMCID: PMC4344302.

Hill DA, Shuker M, Cianferoni A, Wong T, Ruchelli E, Spergel JM, Brown-Whitehorn TF. The development of IgE-mediated immediate hypersensitivity after the diagnosis of eosinophilic esophagitis to the same food. J Allergy Clin Immunol Pract. 2015 Jan-Feb;3(1):123-4. doi: 10.1016/j.jaip.2014.08.005. Epub 2014 Oct 3. PubMed PMID: 25577634; PubMed Central PMCID: PMC5598762.

Gupta M, Grossmann LD, Spergel JM, Cianferoni A. Egg Food Challenges are Associated with More Gastrointestinal Reactions. Children (Basel). 2015 Aug 17;2(3):371-81. doi: 10.3390/children2030371. PubMed PMID: 27417370; PubMed Central PMCID: PMC4928765.

2010

Spergel JM. New genetic links in eosinophilic esophagitis. Genome Med. 2010 Sep 7;2(9):60. [Epub ahead of print]

Brown-Whitehorn TF, Spergel JM. The link between allergies and eosinophilic esophagitis: implications for management strategies. Expert Rev Clin Immunol. 2010 Jan;6(1):101-9. Review. 

Sleiman PM, Flory J, Imielinski M, Bradfield JP, Annaiah K, Willis-Owen SA, Wang K, Rafaels NM, Michel S, Bonnelykke K, Zhang H, Kim CE, Frackelton EC, Glessner JT, Hou C, Otieno FG, Santa E, Thomas K, Smith RM, Glaberson WR, Garris M, Chiavacci RM, Beaty TH, Ruczinski I, Orange JM, Allen J, Spergel JM, Grundmeier R, Mathias RA, Christie JD, von Mutius E, Cookson WO, Kabesch M, Moffatt MF, Grunstein MM, Barnes KC, Devoto M, Magnusson M, Li H, Grant SF, Bisgaard H, Hakonarson H. Variants of DENND1B associated with asthma in children. N Engl J Med. 2010 Jan 7;362(1):36-44. Epub 2009 Dec 23. Erratum in: N Engl J Med. 2010 Sep 2;363(10):994.

Rothenberg ME, Spergel JM, Sherrill JD, Annaiah K, Martin LJ, Cianferoni A, Gober L, Kim C, Glessner J, Frackelton E, Thomas K, Blanchard C, Liacouras C, Verma R, Aceves S, Collins MH, Brown-Whitehorn T, Putnam PE, Franciosi JP, Chiavacci RM, Grant SF, Abonia JP, Sleiman PM, Hakonarson H. Common variants at 5q22 associate with pediatric eosinophilic esophagitis. Nat Genet. 2010 Apr;42(4):289-91. Epub 2010 Mar 7.

Franciosi JP, Fiorino K, Ruchelli E, Shults J, Spergel J, Liacouras CA, Leonard M. Changing Indications for Upper Endoscopy in Children During a 20-year Period. J Pediatr Gastroenterol Nutr. 2010 Jun 16. [Epub ahead of print]

Books

Atopic Dermatitis in Childhood and Adolescence,  Kiess W, Werfel T, Spergel JM (eds):. Pediatr Adolesc Med. Basel, Karger, 2011

Chapters

2015

Cianferoni, A. Gober, L, Spergel, JM, Food Allergy and Food-Related Disorders, Manual of Allergy and Clinical Immunology for Otolaryngologists, Rosenstreich DL, Fried MR, de Vos GS, Jackman AH(eds) Plural Publishing, 2015.

Spergel JM, Eosinophilic Esophagitis and Allergic Rhinitis, Global Atlas on Allergic Rhinitis and Chronic Rhinosinutitis, European Academy of Allergy and Clinical Immunology, 2015.

2012

Sharma, H and Spergel, JM, Clinical Manifestations of Food Allergy, in Food Allergy: Diagnosis and Management (S. Sicherer, Eds).

2011

Cianferoni, AC and Spergel, JM. Allergy Testing in Eosinophilic Esophagitis, Eosinophilic Esophagitis, (Liacouras, Markowitz, Eds), Elsevier Press, 2011

Spergel, JM. Allergy Evaluation in Eosinophilic Esophagitis., (Liacouras, CA, Markowitz, J Eds) Humana Press, 2011

Brown-Whitehorn, TA, Verma, R, Spergel, JM Eosinophilic Gastrointestinal Diseases, Manual in Allergy and Immunology 5E (Adeleman, Corren, Casale, Eds). Lippincott Press, 2011

2010

Spergel, JM. Treatment of Severe Atopic Dermatitis, In Uptodate, Basow, DS (Ed), Uptodate, Waltham, MA 2010 (Updated 2019)

2009

Spergel, JM. Role of Allergy in Atopic Dermatitis. In: UpToDate, Basow, DS (Ed), UpToDate, Waltham, MA, 2009 (updated 2019)

2008

Spergel, JM and Shuker, M. Nutritional management of eosinophilic esophagitis. Gastrointest Endosc Clin N Am. 2008 Jan;18(1):179-94.

2007

Yan, AC, Lauren, C, Honig, PJ and JM Spergel. “Atopic Dermatitis” in Comprehensive Pediatric Hospital Medicine. Editors,  LA Zaoutis, VW Chaing. Elsevier Publishers, Philadelphia, PA2007. Chapter 155: 981-990.

Heltzer, M and JM Spergel. “Asthma” in Comprehensive Pediatric Hospital Medicine. Editors,  LA Zaoutis, VW Chaing. Elsevier Publishers, Philadelphia, PA2007. Chapter 75: 463-481.

Spergel, J.M. Eosinophilic esophagitis in adults and children: evidence for a food allergy component in many patients, Current Opin in Allergy Clin Immunol, 2007 Jun;7(3):274-278.

2006

Spergel, JM, T Brown-Whitehorn, J Beausoleil, and CA Liacouras.   Author’s Response to Editorial on Atopy Patch Testing in Eosinophilic Esophagitis, Ann Allergy Asthma Immunol 2006; 96 (2): 376-8.

Consultation and referral guidelines citing the evidence: How the allergist-immunologist can help, J Allergy Clin Immunol 2006: 117: S495-523

Spergel, JM and MI. Fogg, Pediatric Asthma. in Conn’s Current Therapy, 2006 Editors RE Rakel and ET Bope. Elsevier Saunders, Philadelphia, PA (in press)

Leung, DY and Spergel, JM, Safety of TIM (Topical Calcineurin Immune Modulators) in Atopic Dermatitis: Evaluation of the Evidence/Should we be Concerned?, Curr Allergy Asthma Rep. 2006 6(4):270-4.

Fonancier, L, E, Charlesworth, JM Spergel and DY Leung. The Black Box Warning for Topical Calcineurin Inhibitors: Looking outside the Box. Ann Allergy Asthma Immunol 2006; 97(1):117-20.

Spergel, J.M. Non-prescription Treatment in Atopic Dermatitis.  US Pharmacy Review 2006: www.touchbriefings.com

2005

Spergel, JM. Atopic march: link to upper airways. Curr Opin Allergy Clin Immunol. 2005; 5(1): 17-21.

Spergel, JM and T Brown-Whitehorn. The Use of Patch Testing in the Diagnosis of Food Allergies. Current Allergy and Asthma Reports 2005; 5: 86-90.

Spergel, JM and JF Fiedler. “Foods/Food Additives” in Asthma Triggers. Immunol Allergy Clin North Am. 2005; 25(1): 149-67.

Spergel, J, ME Rothenberg, and M. Fogg. Eliminating Eosinophilic Esophagitis. Clin. Immunol. 2005; 115(2) 131-2.

Fonacier, L, JM Spergel, EN Charlesworth, E Wheldon, V Beltani, J Bernhisel-Broadbent, M Boguniewicz, and DY Leung. Report of the Topical Calcineurin Inhibitor Task Force of the ACAAI and AAAAI.  April 1, 2005. 

J. Allergy Clin. Immunol. 2005; 115: 1249-53.

Spergel, JM and MI Fogg. Pediatric Asthma. In Conn’s Current Therapy, 2005 872-880.  Editors RE Rakel and ET Bope. Elsevier Saunders, Philadelphia, PA

Spergel, JM   Eosinophilic oesophagitis and pollen. Clin Exp Allergy. 2005; 35(11):1421-2.

2003

Spergel JM. Allergen-Induced Model of Murine Atopic Dermatitis” in Animal Models of Human Inflammatory Diseases, CRC publishers, 2003. Chapter 28: 423-32.

Spergel, JM, Chapter 3, 7 and 10 “Allergies and Asthma; Asthma Day to Day and Asthma Medication” in “Guide to Asthma, The Children Hospital of Philadelphia, 2003

2002

Spergel JM, Clayton R. Pediatric asthma: a review. Biomedicina. 2002; 5 (3): 117-24.

Sullivan KE, Spergel JM,  editors. Genetics of allergic and immunoregulatory disorders. Immunology and Allergy Clinics of North America. 2002; 22 (2).

2001

Spergel JM, Pawlowski NA.  Food allergy.  In:  Mascarenhas M, Piccoli  D, editors. Gastrointestinal disease. Ped. Clinic of North America. 2001; 49(1): 73-96.

Spergel JM, Fiedler JM. Natural history of peanut allergy. Curr Opin in Pediatr. 2001; (6): 517-22.

1997

Spergel JM, Schnieder LC. Atopic dermatitis [review]. Internet J. of Allergy and Immunol. 1997; 1(1) 1-8.

Posters and Presentations

Invited Lectures

2022

Spergel JM. “Role of Allergist and Skin Testing in Eosinophilic Esophagitis” American Academy of Allergy Asthma and Immunology Annual Meeting, Phoenix, AZ. Feb 2022.

Spergel JM. “Role of Allergens in Eosinophilic Esophagitis, Treatment Options in Eosinophilic Esophagitis”, Riyadh, Saudi Arabia. Feb 2022.

2021

Spergel JM. “Changes in the treatment of Eosinophilic Esophagitis, and Multi-Food Oral immunotherapy” Los Angeles Allergy and Asthma Society, Virtual. Nov 2021.

Spergel JM. “Modern Treatment for Atopic Dermatitis”, American College of Asthma Allergy and Immunology Annual Meeting, New Orleans, LA. Oct 2021.

Spergel JM. “Allergic Mechanisms: Crossroads with Food, Environmental and Extraesophageal Atopy (OIT, Food, Environmental) and Case Presentation: Pediatric EGE”, Freston Single Topic Conference, Virtual. Sept 2021.

Spergel JM. “New Food Allergy Guidelines, Updates on Diagnosis and Treatment of Eosinophilic Esophagitis”, Southeast Allergy Societies Annual Meeting-Virtual. Sept 2021.

Spergel JM. “Updates on New Food Allergy Guidelines”, Yale-New Haven Hospital, Pediatric Grand Rounds-virtual. Sept 2021.

Spergel JM. “Treatment of Eosinophilic Gastroenteritis”, GREAT Workshop, FDA. July 2021.

Spergel JM. “Treatment of Eosinophilic Gastroenteritis”, GREAT Workshop, FDA. June 2021.

Spergel JM. “What have we learned from Diet Studies from CEGIR”, American Academy Allergy Asthma Immunology Annual Meeting-Virtual. Feb 2021.

2020

Spergel JM. “Atopic Dermatitis: Bathing to Biologics” Dupont Medical Center. Dec 2020.

Spergel JM. “Diagnosis of EoE from Pediatrics to Adults” Illinois Allergy Society Annual Meeting. Oct 2020.

Spergel JM. “T2 inflammation in Eosinophilic Esophagitis”, American College of Gastroenterology Annual Meeting. Oct 2020.

Spergel JM. “DBV712 Patch Adherence for Peanut Allergy” Food Allergy Anaphylaxis Meeting-Eurobat Digital Meeting. Oct 2020.

Spergel JM. “New developments in Eosinophilic Esophagitis” Northwest Allergy Asthma Society Annual Meeting. Oct 2020.

Spergel JM. “Does treating the skin prevent food allergies” Food Allergy Research Education Retreat, Virtual. Sept 2020.

Spergel JM. “Anaphylaxis in Infants”, World Allergy Organization Annual Meeting-Virtual. June 2020.

Spergel JM. “Pro/Con Debate:  PPI EoE is part of Eosinophilic Esophagitis”, European Academy of Allergy and Clinical Immunology, 2020 Annual Meeting-Virtual. May 2020.

Spergel JM. “Pro/Con Debate:  PPI EoE is part of Eosinophilic Esophagitis”, European Academy of Allergy and Clinical Immunology, 2020 Annual Meeting-Virtual. May 2020.

Spergel JM. “Pathogenesis of Eosinophilic Esophagitis”, NASPGHAN Plenary Session, Montreal, CA. Feb 2020.

Spergel JM. “Th2 Pathway” Wilmington, Delaware. Jan 2020.