Lakshmi Srinivasan, MD, FAAP

Areas of Expertise: Biomarkers in neonatal inflammation, Neonatal sepsis, Novel diagnostic tools in neonatal infection
Locations: Main Campus
Appointments and Referrals: 1-800-TRY-CHOP (1-800-879-2467)

  • Background

    Lakshmi Srinivasan, MBBS, FAAP, is an attending physician in the Division of Neonatology and Newborn Service at The Children's Hospital of Philadelphia and the University of Pennsylvania Health System.

    In addition to her training in Pediatrics and Neonatology, Dr. Srinivasan has received additional training in epidemiology, biostatistics and patient-oriented research through the Center for Clinical Epidemiology and Biostatistics, and the Institute for Translational Medicine and Therapeutics (ITMAT) at the University of Pennsylvania.

    Dr. Srinivasan is pursuing research on neonatal sepsis and meningitis. She is especially interested in the development of novel tools to improve diagnosis and prediction of severity of illness. She is also interested in understanding the impact of the gut microbiome on neonatal health. She has received grants towards her research from the Junior Investigator Pilot Grant Program at the University of Pennsylvania, and the Foerderer Award at The Children's Hospital of Philadelphia. She is also the recipient of the Institute for Translational Medicine and Therapeutics Fellowship.

  • Education and Training

    Medical School

    MBBS - Madras Medical College, Chennai, India

    Internship

    Rotating Internship - Government General Hospital, Chennai, India
    Children's Hospital of Michigan, Detroit, MI

    Residency

    Pediatrics - Children's Hospital of Michigan, Detroit, MI

    Fellowship

    Neonatology - The Children's Hospital of Philadelphia

    Additional Training

    Clinical Research Certificate, Center for Clinical Epidemiology and Biostatistics, University of PennsylvaniaPatient Oriented Research Training Program, Institute for Translational Medicine and Therapeutics, University of Pennsylvania

    Board Certification

    Pediatrics

  • Titles and Academic Titles

    Attending Neonatologist

    Instructor, Department of Pediatrics, Perelman School of Medicine at the University of Pennsylvania

  • Centers and Programs
  • Publications

    Papers

    2014

    Padula, MA; Dewan, ML; Shah, SS; Padula, AM; Srinivasan, L; McGowan, KL; Mahoney, KR; Harris, MC. Risk Factors Associated with Laboratory-confirmed Bloodstream Infections in a Tertiary Neonatal Intensive Care Unit. Pediatr Infect Dis J. 2014 Oct. 33 (10):1027-1032. Read the abstract.

    2013

    Sen P, Yang Y, Navarro C, Silva I, Szafranski P, Kolodziejska KE, Dharmadhikari AV, et a. Novel FOXF1 Mutations in Sporadic and Familial Cases of Alveolar Capillary Dysplasia with Misaligned Pulmonary Veins Imply a Role for its DNA Binding Domain. Hum Mutat. 2013 Jun;34(6)801-11. Read the abstract

    Srinivasan L, Shah SS, Abbasi S, Padula MA, Harris MC. Traumatic Lumbar Punctures in Infants Hospitalized in the Neonatal Intensive Care Unit. Pediatr Infect Dis J. 2013 Apr 25. Read the abstract

    Srinivasan L, Harris MC, Shah SS. Lumbar puncture in the neonate: challenges in decision-making and interpretation. Semin Perinatol. 2012 Dec;36(6):445-53. Read the abstract

    2012

    Srinivasan L, Pisapia JM, Shah SS, Halpern C, Harris MC. Can the 16S ribosomal RNA (rRNA) gene PCR improve the diagnosis of the bacterial meningitis in children? A systematic review. Ann Emerg Med. 2012 Nov;60(5):609-620.e2.

    Srinivasan L, Shah SS, Padula MA, Abbasi S, McGowan KL, Harris MC. Reference Ranges for Cerebrospinal Fluid (CSF) Parameters in Term and Preterm Infants in the Neonatal Intensive Care Unit. Journal of Pediatrics, 2012 Oct;161(4):729-24. Read the abstract

    Srinivasan L, Harris MC. New technologies for the rapid diagnosis of neonatal sepsis. Curr Opin Pediatr 2012;24(2):165-71. Read the abstract