Angela J. Waanders, MD, MPH

Angela J. Waanders, MD, MPH, is an attending physician in the Neuro-Oncology Program at The Children's Hospital of Philadelphia. 

Areas of Expertise: Neuro-Oncology
Locations: Main Campus
Appointments and Referrals: 1-800-TRY-CHOP (1-800-879-2467)

  • Education and Training

    Medical School

    MD - Tulane University School of Medicine, New Orleans, LA

    Residency

    Pediatrics - The Children's Hospital of Philadelphia, Philadelphia, PA 

    Fellowship

    Pediatric Hematology-Oncology -The Children's Hospital of Philadelphia, Philadelphia, PA

    Board Certification

    Hematology-Oncology
    Pediatrics

    Graduate Degree

    MPH - Tulane University School of Public Health & Tropical Medicine, New Orleans, LA

  • Titles and Academic Titles

    Attending Physician

    Assistant Professor of Pediatrics, Perelman School of Medicine at the University of Pennsylvania

  • Conditions Treated
  • Centers and Programs
  • Research Interests

    Pediatric low grade gliomas
    Opsoclonus myoclonus ataxia syndrome

  • Publications

    Books

    Chapters

    Minturn JE, Sievert AJ. Pediatric brain tumors. In: Florin T, Ludwig S. Netter's pediatrics. Philadelphia: Saunders; 2011.

    Abstracts

    2013

    Sievert AJ, Lang SS, Silva A, Brewington D, Mueller S, Haas-Kogan DA, Storm PB, Resnick AC. Rationale for combinatorial therapeutics to inhibit BRAF fusion activation. Mol Cancer Ther. Nov 2013. 12:B272, doi:10.1158/1535-7163.

    2012

    Lang SS, Sievert AJ, Boucher KL, Madsen PJ, Slaunwhite E, Brewington D, Storm PB, Resnick AC. Development of pediatric glioma models for BRAF-targeted therapy. Neurosurgery. 2012 Aug; 71 (2): E575.

    Sievert AJ, Lang SS, Boucher K, Slaunwhite E, Brewington D, Madsen P, Storm PB, and Resnick AC. Characterization of KIAA1549-BRAF Fusion responsiveness to selective BRAF inhibition. Neuro-Oncology. Abstracts from the 15th International Symposium on Pediatric Neuro-Oncology. 2012 June: i1-i168.

    Sievert AJ, Lang SS, Storm PB, Resnick AC. Mechanisms of resistance of BRAF fusions to first generation selective BRAF inhibitors [abstract]. Molecularly Targeted Therapies: Mechanisms of Resistance- American Association of Cancer Research; 2012 May 9-12; San Diego, CA.

    Papers

    2014

    Karajannis MA, Legault G, Fisher MJ, Milla SS, Cohen KJ, Wisoff JH, Harter DH, Goldbery JD, Hochman T, Merkelson A, Bloom MC, Sievert AJ, Resnick AC, Dhall G, Jones DTW, Korshunov A, Pfister SM, Eberhart CG, Zagzag D, and Allen JC. Phase II study of sorafenib in children with recurrent or progressive low-grade astrocytomas. Neuro Oncol. 2014 May 6. [Epub ahead of print]. PMID: 24803676

    2013

    Sievert AJ, Lang SS, Boucher KL, Madsen PJ, Slaunwhite E, Choudhari N, Kellet M, Storm PB, and Resnick AC. Paradoxical activation and RAF inhibitor resistance of BRAF protein kinase fusions characterizing pediatric astrocytomas. PNAS 2013 April; 110 (15): 5957-5962. Epub 2013 Mar 26. PMID: 23533272

    2012

    Stephens, J, Sievert AJ, Judkins AR, Resnick AC, Storm PB, Rushing E, Santi M. Spinal cord ependymomas and myxopapillary ependymomas in the first two decades of life: a clinicopathological and immunohistochemical characterization of 19 cases. J of Neurosurg Pediatr. 2012 Jun; 9 (6):646-53. PMID: 22656257

    Posters and Presentations

    Lectures by Invitation
    2014

    Waanders, AJ. “Opsoclonus Myoclonus Ataxia Syndrome,” Chair Clinical Conference, The Children’s Hospital of Philadelphia, Philadelphia, PA, May 2014.

    2013

    Waanders, AJ. “Congenital brain tumors,” Abington Memorial Hospital Neonatology Grand Rounds, Abington Township, PA, November 2013.

    Waanders, AJ. “Paradoxical activation and RAF inhibitor resistance of BRAF protein kinase fusions characterizing pediatric astrocytomas,” 2013 Pediatric Neuro-Oncology Basic and Translational Research Conference, Fort Lauderdale, FL, May 2013.

  • Awards and Honors

    2014- present, Sanford Endowed Chair for Pediatric Oncology Research
    2009,  Prize- CHOP Research Poster Day 
    1999-2003, Adopt-A-Student Scholarship, Tulane University SOM
    1996,  Philosophy Department Senior Student Award
    1992-1996, Alpha Lambda Delta Honorary Society
    1992-1996, Medallion and HEIS Scholarships for Academic Excellence

  • Editorial and Academic Positions
    Editorial Positions

    2013- present, Reviewer- Molecular Cancer Therapeutics
    2012- present, Reviewer- Journal of Neuro-Oncology
    2011- present, Reviewer- Pediatric Blood and Cancer

    Institutional Committees

    2014- present,  St. Baldrick’s Foundation, Grant Review Committee
    2011- present, Pediatric Protocol Review Committee, Division of Oncology, Children’s Hospital of Philadelphia

  • Leaderships
    Memberships in Professional Organizations

    2013- present, Co-Investigator, Pacific Pediatric Neuro-Oncology Consortium
    2009- 2012, Pediatric Brain Tumor Consortium
    2008- present, American Association for Cancer Research
    2007- present, Society of Neuro-Oncology
    2007- present, Children’s Oncology Group
    2006- present,  American Society of Pediatric Hematology/Oncology
    2006-present, American Society of Clinical Oncology