Mei-Lun Wang, MD

Mei-Lun Wang, MD, is a physician with the Division of Gastroenterology, Hepatology and Nutrition at The Children's Hospital of Philadelphia.

Appointments and Referrals: 1-800-TRY-CHOP

  • Education and Training

    Medical School

    MD - University of Pennsylvania School of Medicine, Philadelphia, PA

    Internship

    Pediatrics - Seattle Children's Hospital, Seattle, WA

    Residency

    Pediatrics (Chief Resident) - Seattle Children's Hospital, Seattle, WA

    Fellowship

    Gastroenterology and Nutrition (clinical and research) - The Children's Hospital of Philadelphia, Philadelphia, PA

    Board Certification

    Pediatric Gastroenterology
    Pediatrics

  • Titles and Academic Titles

    Attending Physician

    Assistant Professor of Pediatrics, University of Pennsylvania School of Medicine

  • Publications

    Books

    Chapters

    2010

    Wang ML: Oral Viscous Budesonide is Beneficial in Pediatric EoE. GI Hepatology News 4(8): 10, 2010.

    2008

    Jatla M, Wang ML, and Mamula P.: A 13 year-old boy with chronic abdominal pain and vomiting. Medscape Journal of Medicine 10(3): 54, 2008.

    2007

    Wang ML and Rustgi AK: Polyps and Polyposis Syndromes. Pediatric Gastroenterology:  The Requisites in Pediatrics (Chapter 22). Liacouras CA and Piccoli DA (eds.). Mosby Elsevier, Philadelphia, PA, Page: 192-199, 2007.

    2003

    Wang ML: Inflammatory Bowel Disease. Saint-Frances Guide to Pediatrics (Chapter 88). Migita DS and Christakis DA (eds.). Lippincott Williams and Wilkins, Philadelphia, Page: 471-77, 2003.

    Wang ML: Gastrointestinal Bleeding. Saint-Frances Guide to Pediatrics (Chapter 90). Migita DS and Christakis DA (eds.). Lippincott Williams and Wilkins, Philadelphia, Page: 482-86, 2003.

    Wang ML: Neonatal Cholestasis (Conjugated Hyperbilirubinemia). Saint-Frances Guide to Pediatrics, Chapter 26. Migita DS and Christakis DA (eds.). Lippincott Williams and Wilkins, Philadelphia, Page: 143-48, 2003.

    2002

    Wang ML and Maller E: A Case of Hepatosplenomegaly. Pediatric Case Reviews 2: 79-86, 2002.

    Abstracts

    2013

    Muir AB, Toltzis S, Noah Y, and Wang ML: Esophageal epithelial cells acquire functional characteristics of activated myofibroblasts in vitro following the development of EMT. Oral presentation at the North American Society for Pediatric Gastroenterology, Hepatology, and Nutrition.   October 2013.

    Whelan KA, Chang S, Muir AB, Masterson J, Benitez AJ, Tetreault MP, Crissey MA, Kong J, Gimotty PA, Falk GW, Katz JP, Lynch JP, Furuta GT, Wang ML, and Nakagawa H.: Autophagy may facilitate epithelial-mesenchymal transition in eosinophilic esophagitis and genetically engineered mouse models of esophagitis.   Oral presentation at Digestive Diseases Week of the American Gastroenterologic Association.  Orlando, FL  May 2013.

    Muir AB, Toltzis S, Modayur PC, and Wang ML.: Altered wound healing properties in esophageal epithelial cells that have undergone EMT. Digestive Diseases Week of the American Gastroenterologic Association. Orlando, FL May 2013.

    Modayur PC, Lee AJ, Tait-Wojno E, Benitez AJ, Muir AB, Toltzis S, Shen D, Noah Y, de Waal Malefyt R, Artis D, and Wang ML. : Preferential expression and food antigen-mediated induction of thymic stromal lymphopoietin in differentiated esophageal epithelial cells in eosinophilic esophagitis. Oral Presentation at Digestive Diseases Week of the American Gastroenterologic Association. Orlando, FL May 2013.

    2012

    Muir AB, Lim DM, and Wang ML: Esophageal epithelial and mesenchymal cross talk leads to features of EMT in vitro. Oral Presentation at Digestive Diseases Week of the American Gastroenterologic Association, San Diego, CA May 2012.

    Modayur PC, Mehta I, Toltzis S, Lim DM, and Wang ML: Environmental triggers of TSLP expression in human esophageal epithelial cells. Poster of Distinction, Digestive Diseases Week of the American Gastroenterologic Association, San Diego, CA May 2012.

    Menard-Katcher C, Hand N, Zahm A, Benitez A, Wang ML, and Friedman JR: MicroRNAs are altered in eosinophilic esophagitis. Digestive Diseases Week of the American Gastroenterologic Association, San Diego, CA May 2012.

    Papers

    2013

    Siracusa MD, Saenz SA, Tait Wojno ED, Kim BS, Osborne LC, Ziegler C, Benitez AJ, Ruymann KR, Farber DL, Sleiman PM, Hakonarson H, Cianferoni A, Wang ML, Spergel JM, Comeau MR, and Artis D: TSLP-mediated extramedullary hematopoiesis promotes allergic inflammation. Immunity In press, In press 2013.

    Noti M, Tait-Wojno ED, Kim BS, Siracusa MC, Giacomin PR, Nair MG, Benitez AJ, Ruymann KR, Muir AB, Hill DA, Chikwava KR, Moghaddam AE, Sattentau QJ, Alex A, Zhou C, Yearley JH, Menard-Katcher P, Kubo M, Obata-Ninomiya K, Karasuyama H, Comeau MR, Brown-Whitehorn T, de Waal Malefyt R, Sleiman, PM, Hakonarson H, Cianferoni A, Falk GW, Wang ML, Spergel JM, and Artis D.: TSLP-Elicited Basophil Responses Can Mediate the Pathogenesis of Eosinophilic Esophagitis. Nature Medicine 19(8): 1005-13, 2013.

    Jyonouchi S, Smith C, Saretta F, Abraham V, Ruymann K, Modayur PC, Wang ML, Spergel JM, and Cianferoni A.: Invariant Natural Killer T Cells in Children with Eosinophilic Esophagitis. Clinical Exp Allergy In press 2013.

    Muir AB, Lim DM, Benitez AJ, Chandramouleeswaran PM, Lee AJ, Ruchelli ED, Spergel JM, and Wang ML.: Esophageal Epithelial-Mesenchymal Cross-Talk Leads to Features of Epithelial to Mesenchymal Transition In Vitro. Experimental Cell Research 319(6): 850-9, Apr 2013 Notes: *Featured article in Global Medical Discovery [ISSN 1929-8536] October, 2013.

    2012

    Spergel JM, Brown-Whitehorn TF, Cianferoni A, Shuker M, Wang ML, Verma R, and Liacouras CA: Identification of Causative Foods in Children with Eosinophilic Esophagitis Treated with an Elimination Diet. Journal of Allergy and Clinical Immunology 130(2): 461-7, August 2012.

  • Awards and Honors

    2013, Fellows' Faculty Honor Roll, Division of GI, Hepatology, and Nutrition, The Children's Hospital of Philadelphia

    2013, Faculty Honor Roll, The Children's Hospital of Philadelphia

    2012, Fellows' Faculty Honor Roll, Division of GI, Hepatology, and Nutrition, The Children's Hospital of Philadelphia

    2012-2015, American Partnership For Eosinophilic Disorders (APFED) and HOPE Research Award

    2012, Society for Pediatric Research

    2008, Faculty Honor Roll, The Children's Hospital of Philadelphia

    2002, Gastroenterology Research Group (GRG) and American Gastroenterological Association (AGA) Fellow Travel Award to attend Digestive Diseases Week (DDW), San Francisco, CA

    2002-2004, NIH Pediatric Research Loan Repayment Award Recipient

    1991, Golden Key National Honor Society

    1991, Phi Beta Kappa

    1987-1991, College Scholar, College of Arts and Sciences, Cornell University

  • Editorial and Academic Positions

    Editorial positions

    Reviewer

    American Journal of Physiology, GI, and Liver Physiology

    Gastroenterology

    Gastroesophageal Reflux (GER) and Gastroesophageal Reflux Disease (GERD) in Children and Adolescents, fact sheets developed by the National Digestive Diseases Information Clearinghouse, the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)

    Innate Immunity

    PLOS One

    Academic and institutional committees

    2013-present, Protective Immunity and Immunopathology Affinity Group
    2011-present, Research Steering Committee, Division of GI, Hepatology, and Nutrition

  • Leaderships

    Academic and institutional committees

    American Board of Pediatrics
    American Gastroenterological Association

    • 2011-present , DDW Abstract Committee, Ischemia and Hypoxia, Basic and Clinical Aspects
    • 2011-present , DDW Abstract Committee, Intestinal Inflammation, Injury, Repair, and Fibrosis
    • 2013, DDW Abstract Selection Committee, Intestinal Injury and Repair
    • 2013, DDW Abstract Selection Committee, Ischemia and Hypoxia, Basic and Clinical Aspects

    FDA

    • 2009-present, Grant Reviewer, Office of Orphan Products Development

    Gastroenterology and Urology Devices Panel, Food and Drug Administration
    Gastroenterology Research Group
    National Institutes of Health
    North American Society for Pediatric Gastroenterology, Hepatology, and Nutrition