John M. Maris, M.D.
Medical School: University of Pennsylvania School of Medicine
Special Training: The Children's Hospital of Philadelphia
Academic Appointment: Professor of Pediatrics, University of Pennsylvania School of Medicine
Dr. Maris is chief of the Division of Oncology at The Children's Hospital of Philadelphia (CHOP) and director of the Center for Childhood Cancer Research. He holds the Giulio D'Angelo Endowed Chair in Neuroblastoma Research. He is a member of the Abramson Family Cancer Research Institute, where he directs the Pediatric Oncology Program in the Abramson Cancer Center at the University of Pennsylvania. He also serves as chairman of the national Children's Oncology Group Neuroblastoma Committee, a research consortium of more than 200 member institutions.
At Children's Hospital, Dr. Maris leads a team of world class clinicians and scientists dedicated to rapidly translating research on childhood cancers from the laboratory to the patient. CHOP is one of the nation's leaders in early phase clinical research that focuses on improving pediatric cancer cure rates and minimizing long-term side effects.
Dr. Maris' specialty is neuroblastoma; he is an expert on the molecular genetics and treatment of this often aggressive and intractable cancer. Under his leadership CHOP strives to be the world's leading neuroblastoma research and treatment center.
Dr. Maris' long study of the disease convinced him that neuroblastoma is a genetic in origin, and that critical insights could be made by discovering the genes that cause it. His work at CHOP is focused on the genetic abnormalities in hereditary and sporadic neuroblastoma. To support their investigations, Dr. Maris and his colleagues have gathered the largest collection of pediatric neuroblastoma cases ever assembled.
In the past few years, the Children's Hospital team has been able to identify the main genes associated with this cancer. Several gene discoveries have led to the development of new therapies, a number of which are now in clinical trials. This represents enormous progress in translating basic and clinical research into improved treatments.
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