Viral Triggers of Alloimmunity and Autoimmunity in Pediatric Lung Transplantation

The purpose of this research study is to determine whether respiratory viral infections such as the flu or a cold can damage transplanted organs. Patients who receive lung transplants may experience rejection of the transplanted lung(s). Rejection occurs when the new lung triggers the body’s defense (immune) system. During this time, special cells are sent out to destroy the new lung and eventually the lung is not able to function as it should.

In some cases, damage from viral infections may lead to rejection of the lung. If doctors are able to determine the effects of respiratory viral infections on the transplanted organ, they may be able to treat respiratory viral infections before they cause harm to the transplanted organ.