# ED Clinical Pathway for Evaluation/Treatment of Children with Hemophilia and CHI

## Factor Information Sheet

### Review patient's dose reminder card, if it is available.

#### Patients with inhibitors

- Novo Seven 90 mcg/kg, repeat in two hours
- Feiba 75 units/kg, NOT to exceed 200 units/kg/day

#### Factor VIII Deficiency (check brand chosen by family)

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- Recombinant Factor VIII products
- Recombinate
- Kogenate FS
- Helixate FS
- Advate
- Xyntha
- Alphanate (plasma derived product contains factor VIII and von Willebrand factor)

### Recombinant Factor VIII Products

Dose: Wt in kg x % desired x 0.5 = # of units to be given

Individual factor recovery may vary. Check the patient's dose card.

______kg x ______% x 0.5 = _____units to be given

Alphanate (labeled in Factor VIII and ristocetin units). Use Factor VIII units for hemophilia A.

Dose: Wt in kg X % desired X 0.5 = # of Factor VIII units to be given

______kg x______% x 0.5 = _____Factor VIII units to be given

### Factor IX Deficiency Benefix (recombinant Factor IX)

Desired % correction x wt. in kg x 1.4 = # of units to be given

_____% x _____kg x 1.4 = _____units to be given

### Von Willebrand Disease

#### Humate-P

Use ristocetin units for Von Willebrand disease. This product is labeled in ristocetin units and in
Factor VIII units. Give no more than 2x target dose as maximum dose.

Desired %
correction x wt. in kg divided by 2 = units to be given

_____% x _____kg x 0.5 = _____ristocetin units to be given