ED Pathway for Evaluation/Treatment of Children with Status Epilepticus

Refractory Status Epilepticus

  Medication Dose (mg/kg) Max Dose (mg) Infusion Rate Considerations

 

Pyridoxine 100 mg
Total dose
(not per kg)
100 IVP   Use in patients:
  • < 2 y.o.
  • Concern for metabolic disease

Higher doses may be needed after INH overdose-call the PCC

4th Agent
Coma Induction

Midazolam
Bolus (x2 if needed)
Infusion

0.2

0.1 mg/kg/hr

10

IVP 1-2 minutes