Clinical Pathway for the Care of the Neonate with Myelomeningocele/Myeloschisis

Antibiotics for Infants with Post-natal Closure

Peri-operative Antibiotics Ampicillin, cefotaxime Order prior to delivery
Start in the SDU within 1 hour of birth
Continue for 48 hours post-op
Then switch to prophylaxis
UTI Prophylaxis Ampicillin
Amoxicillin
50 mg/kg/dose IV every 24 hours if not on full feeds
20 mg/kg/dose po/ng every 24 hours if on full feeds