A condition in which there is a chronic reaction to certain protein chains, commonly referred to as gluten, found in some cereal grains. This reaction causes destruction of the villi in the small intestine, with resulting malabsorption of nutrients.
Patients with celiac disease are more likely to have problems relating to malabsorption, including osteoporosis, tooth enamel defects, central & peripheral nervous system disease, pancreatic disease, internal hemorrhaging, organ disorders (gall bladder, liver, & spleen) and gynecological disorders.
Blood tests will help to diagnose and manage celiac disease. Some children may not have symptoms and are identified only through a screening blood test.
An upper gastrointestinal endoscopy (EGD) needs to be done to confirm the diagnosis of celiac disease. During the endoscopy, a small tissue sample (biopsy) is taken from the small bowel. In celiac disease, this tissue will look inflamed and damaged when it is looked at under the microscope.
Elimination of gluten from the diet improves the symptoms. The lining of the small intestine heals after gluten is removed from the diet. This involves eliminating wheat, rye, barley and sometimes oats.
Treatment of celiac disease is life-long.