Congenital Hyperinsulinism Center

Children's View

The spring issue of Children's View, our Foundation's publication, focuses on HI and CHOP's expertise in treating it.

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Number one in Diabetes and Endocrinology disorders.

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Welcome to the Congenital Hyperinsulinism Center

Congenital Hyperinsulinism (HI) is a disorder that causes low blood sugar (hypoglycemia) in infants and children. Other names that have been used in the past include nesidioblastosis or PHHI (persistent hyperinsulinemic hypoglycemia of infancy).

What's new in HI

Providers can earn free CME credit by completing this online activity co-authored by Dr. Charles A. Stanley, MD, Director of the Congenital Hyperinsulinism Center: Clinical Advances in Pediatric Endocrinology: Focus on: Hyperinsulinism. Free CME offer expires on November 1, 2010.

Registration is also free, but required. Register here, and then visit the CME Center at Endocrine Today to choose either the short version (0.50 CME credits) or the long version (1.00 CME credits) of Dr. Stanley's article.

About the HI Center

Congenital hyperinsulinism is rare; most children's hospitals encounter only one or two cases a year. Since October 1998 the Congenital Hyperinsulinism Center at The Children's Hospital of Philadelphia has evaluated and treated more than 400 patients — making it the largest program of its kind in North America.

Providing full services for congenital hyperinsulinism requires sophisticated multidisciplinary team capabilities. Our Center includes a team of specialists in endocrinology, pediatric surgery, pathology and interventional radiology who have long experience in treating infants with this condition.

In addition, CHOP has a nationally top-ranked neonatal intensive care unit, allowing us to provide seamless care for children with complex conditions.

Unique research

Our Center performs 18F-DOPA PET scanning under an FDA-approved research protocol (for appropriate cases). This innovative imaging technique helps surgeons pinpoint abnormal tissue and focal lesions, sparing healthy cells in the pancreas, significantly reducing the risks of diabetes in patients with focal HI, and potentially leading to a cure. This technology can reduce unnecessary near-total pancreatectomies.

Learn more

Please take a moment to explore our Web site. This site will:

For more information, please contact us at 215-590-7682 or hyperinsulin@email.chop.edu.

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Hyperinsulinism Video

Watch our video
Hope Revealed: Unraveling the mysteries of Hyperinsulinism.

Mackenzie's Story

Mackenzie was diagnosed with Focal Congenital Hyperinsulinism at three months of
age, and came to CHOP for her treatment.
Read Mackenzie's Story.

Nathaniel's Story

Nathaniel traveled from Georgia to Children's Hospital for surgery to
treat his Focal KATP Hyperinsulinism. Read Nathaniel's Story.