Publications: Fetal Surgery for Spina Bifida
The following list of publications will help you in your search for more information. Most are written by members of the Fetal Diagnosis and Treatment team at The Children's Hospital of Philadelphia. If you are unable to obtain any of these publications, please let us know, and we will send copies to you.
Journal articles
2007
Wilson RD, Johnson MP, Bebbington MW, Flake AW, Hedrick HL, Sutton LN, Adzick NS: Does a Myelomeningocele Sac Compared to No Sac Result in Decreased Postnatal Leg Function following Maternal Fetal Surgery for Spina Bifida Aperta. Fetal Diagn Ther 2007;22:348-351.
Danzier E, Johnson P, Bebbington M, Simon E, Wilson RD, Bilaniuk L, Sutton L, Adzick NS:Fetal Head Biometry Assessed by Fetal Magnetic Resonance Imaging following in utero Myelomeningocele Repair. Fetal Diagnosis and Therapy 22:1-6, 2007.
2005
Danzer E, Schwarz U, Wehrli S, Radu A, Adzick NS, Flake AW: Retinoic acid induced myelomeningocele in fetal rats: Characterization by histopathological analysis and magnetic resonance imaging. Experimental Neurology 194:467-75, 2005.
2004
Danzer E, Johnson MP, Wilson RD, Flake AW, Hedrick HL, Sutton LN,Adzick NS. Fetal Head Biometry Following In Utero Repair of Myelomeningocele. Ultrasound in Obstet & Gynecol 2004; 24: 606-611.
2003
N Tulipan, LN Sutton, JP Bruner, BM Cohen, MP Johnson, NS Adzick. The effect of intrauterine Myelomeningocele repair on the incidence of shunt-dependent hydrocephalus. PediatricNeurosurgery 2003; 38:27-33.
MP Johnson, LN Sutton, N Rintoul, TM Crombleholme, AW Flake, LJ Howell, HL Hedrick, RD Wilson, NS Adzick. Fetal myelomeningocele repair: Short Term Clinical Outcomes. Am J Obstet Gynecol 2003; 189(2): 482-487.
LN
Walsh DS, Adzick NS: Fetal surgery for spina bifida. Seminars in Neonatology 8:197-205, 2003.
2000
Olutoye O, Adzick, NS: Fetal surgery for myelomeningocele. Operative Techniques in Plastic and Reconstructive Surgery. 7:82-90, 2000.
1999
Sutton LS, Adzick NS, Bilaniuk LT, Johnson MP, Crombleholme TM, Flake AW. Improvement in hindbrain herniation demonstrated by serial fetal magnetic resonance imaging following fetal surgery for myelomeningocele. JAMA. 282 :1826-1831, 1999
1998
Adzick NS, Sutton LN, Crombleholme TM, Flake AW: Successful fetal surgery for spina bifida. Lancet 352:1675-1676, 1998.
1997
Meuli-Simmen C, Meuli M, Yingling CD, Eiman T, Timmel GB, Buncke HJ, Linenweaver W, Harrison MR, Adzick NS: Midgestational sciatic nerve transection in fetal sheep results in absent nerve regeneration and neurogenic muscle atrophy. Plast Reconstr Surg 99:486-492, 1997.
Meuli M, Meuli-Simmen C, Hutchins GM, Seller MJ, Harrison MR, Adzick NS: The spinal cord lesion in human fetuses with myelomeningocele: Implications for fetal surgery. J Pediatr Surg 32:448-452, 1997.
Meuli-Simmen C, Meuli M, Adzick NS, Ursell PC, Harrison MR: Latissimus dorsi flap procedure to cover myelomeningocele in utero: A feasibility study in human fetuses. J Pediatr Surg 32:1154-1156, 1997.
1996
Meuli M, Meuli-Simmen C, Hutchins GM, Yingling CD, Hutchins GM, Timmel GB, Harrison MR, Adzick NS: In utero repair of experimental myelomeningocele spares neurologic function at birth. J Pediatr Surg 31:397-402, 1996.
Meuli-Simmen C, Meuli M, Hutchins GM, Yingling CD, Timmel GB, Harrison MR, Adzick NS: The fetal spinal cord does not regenerate after in utero transection in a large mammalian model. Neurosurgery 39:555-561, 1996.
Hoffman KM, Timmel GB, Meuli-Simmen C, Meuli M, Yingling CD, Adzick NS: Experimental fetal neurosurgery: The normal neurology of neonatal lambs and abnormal findings after in utero manipulation. Contemporary Topics in Laboratory Animal Medicine 35:53-56, 1996.
1995
Meuli M, Meuli-Simmen C, Hutchins GM, Yingling CD, Hoffman KM, Harrison MR, Adzick NS: In utero surgery rescues neurologic function at birth in sheep with spina bifida. Nature Medicine 1:342-347, 1995.
Meuli-Simmen C, Meuli M, Hutchins GM, Harrison MR, Buncke HJ, Sullivan KM, Adzick NS: Fetal reconstructive surgery: Experimental use of latissimus dorsi flap to correct myelomeningocele in utero. Plastic Reconstructive Surgery 96:1007-1011, 1995.
Meuli-Simmen C, Meuli M, Yingling CD, Eiman T, Timmel GB, Buncke HJ, Linenweaver W, Harrison MR, Adzick NS: Failure of the fetal sciatic nerve to regenerate at midgestation. Surgical Forum 46:689-692, 1995.
Meuli M, Meuli-Simmen C, Yingling CD, Hoffman KB, Harrison MR, Adzick NS: Creation of myelomeningocele in utero: A model of functional damage from spinal cord exposure in fetal sheep. J Pediatr Surg 30:1028 1033, 1995.
1994
Meuli M, Meuli-Simmen C, Yingling CD, Hoffman KB, Harrison MR, Adzick NS: A new model of myelomeningocele: Studies in the fetal lamb. Surgical Forum 45:587-589, 1994.
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