Center for Pediatric Inflammatory Bowel Disease

Publications About Inflammatory Bowel Disease

2013

Cardinale CJ, Kelsen JR, Baldassano RN, & Hakonarso, H. (2013). Impact of exome sequencing in inflammatory bowel disease. World Journal of Gastroenterology: WJG, 19(40), 6721. Read abstract.

Cardinale CJ, Wei Z, Panossian S, Wang F, Kim CE, Mentch FD, Chiavacci RM, Kachelries KE, Pandey R, Grant SF, Baldassano RN, Hakonarson H. (2013). Targeted resequencing identifies defective variants of decoy receptor 3 in pediatric-onset inflammatory bowel disease. Genes and immunity. Read abstract.

Gupta K, Noble A, Kachelries KE, Albenberg L, Kelsen JR, Grossman AB, Baldassano RN. (2013). A novel enteral nutrition protocol for the treatment of pediatric Crohn's disease. Inflammatory Bowel Diseases. [In process] Read abstract.

Tsampalieros A, Lam CK, Spencer JC, Thayu M, Shults J, Zemel BS, Herskovitz RM, Baldassano RN, Leonard MB. (2013). Long term inflammation and glucocorticoid therapy impair skeletal modeling during growth in childhood Crohn's disease. Journal of Clinical Endocrinology & Metabolism. Read abstract.

Walters TD, Kim M, Denson LA, Griffiths AM, Dubinsky M, Markowitz J, Baldassano R, Crandall W, Rosh J, Pfefferkorn M, Otley A, Heyman MB, Leleiko N, Baker S, Guthery SL, Evans J, Ziring D, Kellermayer R, Stephens M, Mack D, Oliva-Hemker M, Patel AS, Kirschner B, Moulton D, Cohen S, Kim S, Liu C, Essers J, Kugathasan S, Hyams JS. (2013). Comparative effectiveness of early therapy with anti-tumor necrosis factor-α vs. an immunomodulator in children With Crohn’s disease. Gastroenterology. Read abstract.

Wei Z, Wang W, Bradfield J, Li J, Cardinale C, Frackelton E, Kim C, Mentch F, Van Steen K, Visscher PM, Baldassano RN, Hakonarson H (2013). Large sample size, wide variant spectrum, and advanced machine-learning technique boost risk prediction for inflammatory bowel disease. The American Journal of Human Genetics. Read abstract.

Zeisler B, Lerer T, Markowitz J, Mack D, Griffiths A, Bousvaros A, ... & Hyams J. (2013). Outcome following aminosalicylate therapy in children newly diagnosed as having ulcerative colitis. Journal of Pediatric Gastroenterology and Nutrition, 56(1), 12-18. Read abstract

2012

Gray WN, Denson LA, Baldassano RN, & Hommel KA. (2012). Treatment adherence in adolescents with inflammatory bowel disease: the collective impact of barriers to adherence and anxiety/depressive symptoms. Journal of Pediatric Psychology, 37(3), 282-291. Read abstract.

Guilfoyle SM, Denson LA, Baldassano RN, & Hommel KA. (2012). Paediatric parenting stress in inflammatory bowel disease: application of the Pediatric Inventory for Parents. Child: Care, Health and Development, 38(2), 273-279. Read abstract.

Hyams JS, Griffiths A, Markowitz J, Baldassano RN, Faubion WA Jr, Colletti RB, Dubinsky M, Kierkus J, Rosh J, Wang Y, Huang B, Bittle B, Marshall M, Lazar A. (2012). Safety and efficacy of adalimumab for moderate to severe Crohn's disease in children. Gastroenterology, 143(2), 365-374. Read abstract.

Hyams J, Damaraju L, Blank M, Johanns J, Guzzo C, Winter HS, Kugathasan S, Cohen S, Markowitz J, Escher JC, Veereman-Wauters G, Crandall W, Baldassano R, Griffiths A2012). Induction and maintenance therapy with infliximab for children with moderate to severe ulcerative colitis. Clinical Gastroenterology and Hepatology, 10(4), 391-399. Read abstract.

Kelsen, JR, & Wu, GD. (2012). The gut microbiota, environment and diseases of modern society. Gut Microbes, 3(4), 374-382. Read abstract.

Otley A, LeLeiko N, Langton C, Lerer T, Mack D, Evans J, ... & Hyams J. (2012). Budesonide use in pediatric Crohn's disease. Journal of Pediatric Gastroenterology and Nutrition, 55(2), 200-204. Read abstract.

Prosnitz AR, Leonard MB, Shults J, Zemel BS, Hollis BW, Denson LA, Baldassano RN, Cohen AB, Thayu M. (2012). Changes in vitamin D and parathyroid hormone metabolism in incident pediatric Crohn's disease. Inflammatory Bowel Diseases. Read abstract.

Yatsunenko T, Rey FE, Manary MJ, Trehan I, Dominguez-Bello MG, Contreras M, Magris M, Hidalgo G, Baldassano RN, Anokhin AP, Heath AC, Warner B, Reeder J, Kuczynski J, Caporaso JG, Lozupone CA, Lauber C, Clemente JC, Knights D, Knight R, Gordon JI.. (2012). Human gut microbiome viewed across age and geography. Nature, 486(7402), 222-227. Read abstract.

2011

Albenberg LG, Lewis JD, & Wu GD. (2012). Food and the gut microbiota in inflammatory bowel diseases: a critical connection. Current Opinion in Gastroenterology, 28(4), 314-320. Read abstract.

Anderson CA, Boucher G, Lees CW, Franke A, D'Amato M, Taylor KD, ... Baldassano RN,… & Mowat C. (2011). Meta-analysis identifies 29 additional ulcerative colitis risk loci, increasing the number of confirmed associations to 47. Nature Genetics, 43(3), 246-252. Read abstract.

Gray WN, Denson LA, Baldassano RN, & Hommel KA. (2011). Disease activity, behavioral dysfunction, and health‐related quality of life in adolescents with inflammatory bowel disease. Inflammatory Bowel Diseases,17(7), 1581-1586. Read abstract.

Herzer M, Denson LA, Baldassano RN, & Hommel KA. (2011). Family functioning and health-related quality of life in adolescents with pediatric inflammatory bowel disease. European Journal of Gastroenterology & Hepatology, 23(1), 95. Read abstract.

Herzer M, Denson LA, Baldassano RN, & Hommel KA. (2011). Patient and parent psychosocial factors associated with health-related quality of life in pediatric inflammatory bowel disease. Journal of Pediatric Gastroenterology and Nutrition, 52(3), 295. Read abstract.

Hommel KA, Denson LA, & Baldassano RN. (2011). Oral medication adherence and disease severity in pediatric inflammatory bowel disease. European Journal of Gastroenterology & Hepatology, 23(3), 250. Read abstract.

Hommel KA, Odell S, Sander E, Baldassano RN, & Barg FK. (2011). Treatment adherence in paediatric inflammatory bowel disease: perceptions from adolescent patients and their families. Health & Social Care in the Community, 19(1), 80-88. Read abstract.

Hyams JS, Lerer T, Mack D, Bousvaros A, Griffiths A, Rosh J, … Grossman A,  ... & Markowitz J. (2011). Outcome following thiopurine use in children with ulcerative colitis: a prospective multicenter registry study. The American Journal of Gastroenterology, 106(5), 981-987. Read abstract.

Hyams J, Walters TD, Crandall W, Kugathasan S, Griffiths A, Blank M, ... & Baldassano R. (2011). Safety and efficacy of maintenance infliximab therapy for moderate-to-severe Crohn's disease in children: REACH open-label extension. Current Medical Research & Opinion, 27(3), 651-662. Read abstract.

Kelsen JR, Kim J, Latta D, Smathers S, McGowan KL, Zaoutis T, ... & Baldassano RN. (2011). Recurrence rate of Clostridium difficile infection in hospitalized pediatric patients with inflammatory bowel disease. Inflammatory Bowel Diseases, 17(1), 50-55. Read abstract.

Odell S, Sander E, Denson LA, Baldassano RN, & Hommel KA. (2011). The contributions of child behavioral functioning and parent distress to family functioning in pediatric inflammatory bowel disease. Journal of Clinical Psychology in Medical Settings, 18(1), 39-45. Read abstract.

Turner D, Travis SP, Griffiths AM, Ruemmele FM, Levine A, Benchimol EI, ... Baldassano RN,…& Russell RK. (2011). Consensus for managing acute severe ulcerative colitis in children: a systematic review and joint statement from ECCO, ESPGHAN, and the Porto IBD Working Group of ESPGHAN. The American Journal of Gastroenterology, 106(4), 574-588. Read abstract.

Wu GD, Chen J, Hoffmann C, Bittinger K, Chen YY, Keilbaugh SA, Bewtra M, Knights D, Walters WA, Knight R, Sinha R, Gilroy E, Gupta K, Baldassano R, Nessel L, Li H, Bushman FD, Lewis JD. (2011). Linking long-term dietary patterns with gut microbial enterotypes. Science, 334(6052), 105-108. Read abstract.

Zahm AM, Thayu M, Hand NJ, Horner A, Leonard MB, & Friedman JR. (2011). Circulating microRNA is a biomarker of pediatric Crohn's disease. Journal of Pediatric Gastroenterology and Nutrition, 53(1), 26-33. Read abstract.

2010

Franke A, McGovern DP, Barrett JC, Wang K, Radford-Smith GL, Ahmad T, ... Baldassano RN,… & Van Gossum A. (2010). Genome-wide meta-analysis increases to 71 the number of confirmed Crohn's disease susceptibility loci. Nature genetics, 42(12), 1118-1125. Read abstract.

Gupta N, Bostrom AG, Kirschner BS, Ferry GD, Gold BD, Cohen SA, Winter HS, Baldassano RN, Abramson O, Smith T, Heyman MB. (2010). Incidence of stricturing and penetrating complications of Crohn's disease diagnosed in pediatric patients. Inflammatory Bowel Diseases, 16(4), 638-644. Read abstract.

Hommel KA, & Baldassano RN. (2010). Brief report: Barriers to treatment adherence in pediatric inflammatory bowel disease. Journal of Pediatric Psychology, 35(9), 1005-1010. Read abstract.

Hyams JS, Lerer T, Griffiths A, Pfefferkorn M, Stephens M, Evans J, … Grossman A ... & Markowitz J. (2010). Outcome following infliximab therapy in children with ulcerative colitis. The American Journal of Gastroenterology. Read abstract.

Ingerski LM, Baldassano RN, Denson LA, & Hommel KA. (2010). Barriers to oral medication adherence for adolescents with inflammatory bowel disease. Journal of Pediatric Psychology, 35(6), 683-691. Read abstract.

Kelsen JR, Rosh J, Heyman M, Winter HS, Ferry G, Cohen S, ... & Baldassano RN. (2010). Phase I trial of sargramostim in pediatric Crohn's disease. Inflammatory Bowel Diseases, 16(7), 1203-1208. Read abstract.

Mascarenhas MR, & Thayu M. (2010). Pediatric inflammatory bowel disease and bone health. Nutrition in Clinical Practice, 25(4), 347-352. Read abstract.

Thayu M, Denson LA, Shults J, Zemel BS, Burnham JM, Baldassano RN, ... & Leonard MB. (2010). Determinants of changes in linear growth and body composition in incident pediatric Crohn's disease. Gastroenterology, 139(2), 430-438. Read abstract.

Wang K, Baldassano R, Zhang H, Qu HQ, Imielinski M, Kugathasan S, ... & Hakonarson, H. (2010). Comparative genetic analysis of inflammatory bowel disease and type 1 diabetes implicates multiple loci with opposite effects. Human Molecular Genetics, 19(10), 2059-2067. Read abstract.

2009

Ingerski LM, Baldassano RN, Denson LA, Hommel KA. (2009) Barriers to oral medication adherence for adolescents with inflammatory bowel disease. Journal of Pediatric Psychology, 1-9. Read abstract.

Gupta N, Bostrom AG, Kirschner BS, Ferry GD, Gold BD, Cohen SA, et al. (2009). Incidence of stricturing and penetrating complications of Crohn's disease diagnosed in pediatric patients. Inflammatory Bowel Diseases, 2009 Sept. 6 (Epub ahead of print)  Read abstract.

Wang K, Zhang H, Kugathasan S, Annese V, Bradfield JP, Russell RK, (2009). Diverse genome-wide association studies associate the IL12/IL23 pathway with Crohn Disease. American Journal of Human Genetics, 84, 399 -405 Read abstract.

Colletti RB, Baldassano RN, Milov DE, Margolis PA, Bousvaros A, Crandall WV, et al. (2009). Variation in care in pediatric Crohn's disease. Journal of Pediatric Gastroenterology and Nutrition, 49(3), 297–303. Read abstract.

Crandall W, Hyams J, Kugathasan S, Griffiths A, Zrubek J, Olson A, et al. (2009). Infliximab therapy in children With concurrent perianal Crohn's disease: observations from REACH. Journal of Pediatric Gastroenterology and Nutrition, 49(2), 183–190 Read abstract.

Liu S, Russo PA, Baldassano RN, Sullivan KE. (2009). CD68 expression is markedly different in Crohn's disease and the colitis associated with chronic granulomatous disease. Inflammatory Bowel Disease, 15, 1213-1217. Read abstract.

Miele E, Pascarella F, Giannetti E, Quaglietta L, Baldassano RN, Staiano A. (2009) Effect of a probiotic preparation (VSL#3) on induction and maintenance of remission in children with ulcerative colitis. American Journal of Gastroenterology, 104:437–443. Read abstract.

Heyman MB, Garnett EA, Shaikh N, Huen K, Jose FA, Harmatz P, Winter HS, et al. (2009) Folate concentrations in pediatric patients with newly diagnosed inflammatory bowel disease. American Journal of Clinical Nutrition, 89, 545-550. Read abstract.

Dubner SE, Shults J, Baldassano RN, Zemel BS, Thayu M, Burnham JM, et al. (2009). Longitudinal assessment of bone density and structure in an incident cohort of children with Crohn's disease. Gastroenterology, 136, 123 -130 Read abstract.

Hommel KA, Davis CM, Baldassano RN. (2009). Objective versus subjective assessment of oral medication adherence in pediatric inflammatory bowel disease. Inflammatory Bowel Disease, 15, 589-59. Read abstract.

Jose FA, Garnett EA, Vittinghoff E, Ferry GD, Winter HS, Baldassano RN, et al. (2009). Development of extraintestinal manifestations in pediatric patients with inflammatory bowel disease. Inflammatory Bowel Disease, 15, 63-68. Read abstract.

Imielinski M, Baldassano RN, Griffiths A, Russell RK, Annese V, Dubinsky M, Kugathasan S, Bradfield JP, Walters TD, Sleiman P, Kim CE, Muise A, Wang K, Glessner JT, Saeed S, Zhang H, Frackelton EC, Hou C, Flory JH, Otieno G, Chiavacci RM, Grundmeier R, Castro M, Latiano A, Dallapiccola B, Stempak J, Abrams DJ, Taylor K, McGovern D; Western Regional Research Alliance for Pediatric IBD; International IBD Genetics Consortium, Heyman MB, Ferry GD, Kirschner B, Lee J, Essers J, Grand R, Stephens M, Levine A, Piccoli D, Van Limbergen J, Cucchiara S, Monos DS, Guthery SL, Denson L, Wilson DC, Grant SF, Daly M, Silverberg MS, Satsangi J, Hakonarson H. (2009) Common variants at five new loci associated with early-onset inflammatory bowel disease. National Genetics, Nov 15. [Epub ahead of print] Read abstract.

Reviewed by: IBD team
Date: January 2014

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