Immunogenetics Laboratory

Engraftment Monitoring: Post-Bone Marrow Transplant - Patient

  • Synonyms: Chimerism, STR, VNTR, Engraftment
  • LIS Mnemonic: ENGRAFTMENT POS

    Collect

    Lavender (EDTA) or Bone Marrow (1ml)

    Volume Required

    4 ml; 8ml for Lineage Specific Analysis

    Minimum Required

    1 ml; 8ml for Lineage Specific Analysis

    Transport

    Room temperature

    Stability

    72 hrs

    Unacceptable conditions

    Samples older than 72 hours. Mislabeled samples: Samples must be labeled with at least two different identifiers, date & time of collection, and collector's signature.

Days Performed

Monday -Friday

Reported

3 days

Reflex Testing

N/A

CPT

83890, 83898 (x10), 83909, 83912

Methodology

PCR of microsatellite markers/short tandem repeats (STRs)

Remarks

This test is ordered on post-transplant patient specimens. Lineage specific analysis (LSA) is available for T Cells (CD3+), B Cells (CD19+), Lymphoid Cells (CD3+/CD19+), and Myeloid Cells (CD33+).

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