Bone marrow in EDTA anticoagulated tube
Keep specimen at 4C
Amplification and detection of CMV DNA polymerase gene using TaqMan real-time PCR technology. This test is performed pursuant to an agreement with Roche Molecular Systems, Inc.
If positive, results are reported as cytomegalovirus DNA detected.
Negative or no cytomegalovirus DNA detected
Clinical Utility: CMV infections are common and usually asymptomatic in otherwise healthy children and adults; however, the incidence and spectrum of disease in newborns and in immunocompromised hosts establish this virus as an important human pathogen. PCR of bone marrow can be helpful in patients suspected of having CMV-associated bone marrow suppression, hemophagocytic syndrome, hemolytic anemia, and an atypical lymphocytosis.