Neonatology Research
The Children's Hospital of Philadelphia is a leader in the advancement of basic and clinical research. We have one of the nation's largest pediatric research programs, spanning virtually every area of pediatric medicine. The new knowledge that is gained from our studies will lead to improved healthcare for children worldwide.
Our clinical and basic research activities are conducted through the Children's Hospital of Philadelphia Research Institute. The Institute oversees the work of more than 150 investigators and their staffs who are pursuing hundreds of active research projects at any given time. Children's Hospital ranks among the top two pediatric hospitals nationwide in National Institutes of Health funding.
Our current areas of research interest in Neonatology include:
- Fetal lung development
- Lung antioxidant defenses
- Oxidative stress mediated gene regulation
- Surfactant protein processing and physiology
- Hormone regulation of fetal lung development
- Lung disease in premature infants
- Role of inflammation in lung disease
- Congenital diaphragmatic hernia and complex lung lesions
- Biological chemistry and molecular mechanisms of action in nitric oxide
- Use of inhaled nitric oxide in premature infants
- Intrauterine growth retardation and insulin resistance
- Fetal origins of adult disease
- Effect of maternal obesity on the fetus
- Mitochrondrial biology
- Development of the conotruncal region of the heart
- Biomarkers of neonatal sepsis
- Serum biomarkers in necrotizing enterocolitis
- Neonatal pharmacokinetics
- Effect of inflammation and oxidative stress on the neonatal brain
- Neuroimaging and neurodevelopmental outcomes
- Biomarkers and neonatal brain injury
- Maternal drug use and neonatal neurodevelopmental outcome
- Management of myelomeningoceles
- Neonatal health services research
- Multicenter trials to assess safety and efficacy of neonatal therapies
- Simulation strategies for neonatal education
- Impact of neonatal outreach on referral patterns
- Community satisfaction of neonatal level 4 care
Researchers and publications
Meet our neonatology researchers
View selected neonatal research publications
View a selected list of current clinical studies