Research
The Children's Hospital of Philadelphia is a leader in the advancement of basic and clinical research. We have one of the nation's largest pediatric research programs, spanning virtually every area of pediatric medicine. The new knowledge that is gained from our studies will lead to improved healthcare for children worldwide.
Our clinical and basic research activities are conducted through the Children's Hospital of Philadelphia Research Institute. The Institute oversees the work of more than 150 investigators and their staffs who are pursuing hundreds of active research projects at any given time. Children's Hospital ranks among the top two pediatric hospitals nationwide in National Institutes of Health funding.
Neonatology research
Current areas of neonatal research include:
- The role and regulation of heme oxygenase in lung antioxidant defenses
- Surfactant protein processing and physiology
- Surfactant clinical trials — booster prophylaxis and rescue therapy
- Intrauterine growth retardation and insulin resistance
- Cell motility and proliferation; process of inflammation and fibrosis following tissue injury
- Fetal lung development
- Hormone regulation of fetal lung development
- Lung disease in premature infants
- Biological chemistry and molecular mechanisms of action of nitric oxide and oxidants
- Use of inhaled nitric oxide in premature infants
- Development of the conotruncal region of the heart
- Pulmonary function testing in the neonate
- Management of myelomeningoceles
Learn more about neonatology research at The Children's Hospital of Philadelphia.
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