Related Research
The Division of Plastic and Reconstructive Surgery's team of physicians focus not only on providing the best possible care for our patients, but also on research that will improve treatment and quality of life for the children we serve.
Our Division has been a leader in pediatric plastic surgery research, both clinical and bench, for decades. In addition, we benefit from the close proximity of the research lab of the University of Pennsylvania’s Division of Plastic Surgery, located at the Leonard and Madlyn Abramson Pediatric Research Center at The Children’s Hospital of Philadelphia.
Clinical research involves long-term results of surgical therapy, innovative treatment with novel devices and techniques, psychological outcomes of surgery, and children with facial and body differences. Our basic research laboratory investigates disease mechanisms and treatment for a variety of congenital disorders.
Basic science research
- Biocompatibility, osteoconductivity, and remodeling capacity of Norian CRS bone cement in the immature craniofacial skeleton. (Scott P. Bartlett, MD)
- Effects of intrauterine constraint on craniofacial development.
- Effects of biomechanical force on the dura mater and calvarial bone.
- Influence of TGF-beta isoforms on dural and calvarial bone cell growth and differentiation.
- Pediatric craniofacial reconstruction using Norian CRS: Influence on craniofacial growth. (Scott P. Bartlett, MD)
- Synthetic hybrid grafts for gene therapy in craniofacial reconstruction.
- Synthetic hybrid grafts for gene therapy in chronic wound healing. (Timothy Crombleholme, MD)
Clinical outcomes research
- Chromosome 22q11.2 deletion syndrome: Palatal phenotypes and surgical outcomes. (Plastic and Reconstructive Surgery team physicians)
- Clinical outcomes in cleft lip and palate surgery. (Plastic and Reconstructive Surgery team physicians)
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