Trisomy 21 Program

The Trisomy 21 Program at Children's Hospital of Philadelphia evaluates, treats and provides coordinated multidisciplinary care for children and adults with trisomy 21 — also known as Down syndrome.

Trisomy 21: Bryant’s Story

Conditions We Treat

Our Team

The Trisomy 21 team consists of experts who specialize in caring for both pediatric and adult patients with trisomy 21, including pediatricians, neurologists, nurse practitioners, physical therapists and social workers.


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John and Sara's Story

John and Sara have been coming to CHOP's Trisomy 21 Program all of their lives. Learn about how their care transitioned as they grew up.

evan and his parents

Evan's Story

Born with Down syndrome, Evan has been treated at CHOP since he was a baby. His family shares how that care has made a difference in Evan’s life.

Mom holding child

Trisomy 21 Parent Peer Program

This program offers social, emotional and informational support to parents, caregivers and siblings of individuals with Down syndrome.