I am the director of the Stem Cell Laboratory, and was instrumental in creating this laboratory at Children's Hospital.
Our pediatric facility was one of the first in the country to perform bone marrow transplants starting in 1976. We have processed stem cells for more than 1,000 transplants, making us one of the most experienced labs in the country.
We work closely with oncology clinicians and researchers on the multiple research projects that are ongoing at Children's Hospital.
Our state-of-the-art laboratory is involved in all aspects of stem cell processing. We prepare bone marrow, peripheral blood stem cells and umbilical cord blood cells for patients undergoing autologous (self) or allogeneic (donor) transplants.
Transplants are performed for patients with hematological malignancies, aplastic anemia, brain tumors, neuroblastoma, inborn errors of metabolism or immunodeficiencies.
Our research is involved in developing and evaluating new and better protocols to improve transplantation outcomes and reduce the risk of complications.
We also focus on methods to reduce the risk of graft versus host disease (GVHD) and lymphoproliferative disease in our pediatric population. This includes manipulating the graft to enrich it for cells that are necessary for engraftment and to remove cells that can cause complications.
The Stem Cell Laboratory is rigorously monitored by several accrediting agencies. It is registered and inspected by the Food and Drug Administration (FDA), and accredited by the Foundation for the Accreditation of Cellular Therapy (FACT), the College of American Pathologists (CAP) and the Pennsylvania Department of Health.
We also participate in many educational activities including those sponsored by the International Society for Cellular Therapy (ISCT) and the PACT Group, an initiative committed to the advancement of effective cell therapies.
« Back to Previous Page