The Children's Hospital of Philadelphia
www.chop.edu
Unraveling the Mysteries of Hyperinsulinism - The Promise of the Future

Charles A. Stanley, MD: Currently the F-DOPA PET scan is available under the FDA IMD protocol and the protocol is written to only do it in babies that require surgery.

Laura Ann Warner, NP: Because of our great success we now anticipate that we will start doing PET scans on children who are medically responsive.

N. Scott Adzick, MD: Children who are now managed medically reasonably well could be put in the diagnostic pipeline, have a PET scan, have a focal lesion diagnosed and then have a definitive cure by operation and not have to have potentially a lifetime of medical treatment and a risk of hypoglycemia.

Charles A. Stanley, MD: We've opened up the possibility of being able to do laparoscopic surgery.

N. Scott Adzick, MD: Now we're just beginning to apply that to focal lesions and we can do that because we have the PET scan technology.

Charles A. Stanley, MD: With laparoscopic surgery the babies can potentially be eating again the evening after surgery.

N. Scott Adzick, MD: As opposed to having to wait a week after a big laparotomy.

Eduardo Ruchelli, MD: Every time you remove tissue from the body obviously the consequences are significant.

N. Scott Adzick, MD: I am sure that we will be able to apply in a highly specific manner the PET scanning technology in the operating room.

Charles A. Stanley, MD: This could be done with a probe like a geiger counter that can be traced along the pancreas.

Abass Alavi, MD: To even define the boundaries of these lesions more precisely than we can by external imaging.

N. Scott Adzick, MD: To be more highly specific in exactly how much pancreas one removes.

Lori Prinz Halaby, NP: I would love to never see any of these families suffer in the way that they have suffered.

Abass Alavi, MD: I will do anything that I can to promote the sciences that are going to make human beings not to suffer or suffer less and this is exactly what motivates me every day.

N. Scott Adzick, MD: What motivates me are the patients, the children. If you can definitively cure a child with hyperinsulinism by what your team can do, I mean that's incredibly gratifying.

Eduardo Ruchelli, MD: For these children to be potentially cured it's extremely rewarding.

Charles A. Stanley, MD: It’s been our particular privilege to try to provide the resources and the expertise to help these families deal with this very difficult problem.