Yimei Li, PhD

Education and Training

Undergraduate Degree

BS in Applied Mathematics - Peking University, Beijing, China

Graduate Degree

PhD in Biostatistics - University of Pennsylvania, Philadelphia, PA

MS in Biostatistics - University of Pennsylvania, Philadelphia, PA

Titles and Academic Titles

Faculty Biostatistician

Associate Professor of Biostatistics, Perelman School of Medicine at the University of Pennsylvania

Associate Professor of Pediatrics, Perelman School of Medicine at the University of Pennsylvania

Departments and Services

Areas of Focus




Li Y, Nelson R, Izem R, Broglio K, Gamalo M, Mundayat R, Pan H, Sun H, Ye J (2024). Unlocking the potential: A systematic review of master protocol in pediatrics. Therapeutic Innovation & Regulatory Science, 2024 Feb. Online ahead of print 

Cao L, Huang YS, Getz K, Seif A, Ruiz J, Miller T, Fisher B, Aplenc R, Li Y: Applying machine learning to identify pediatric patients with newly diagnosed acute lymphoblastic leukemia using administrative data. Pediatric Blood & Cancer 71(3): e30858, Mar 2024


Cao L, Huang YS, Wu C, Getz K, Miller TP, Fisher BT, Fisher B, Seif A, Aplenc R, Li Y: Leveraging machine learning to identify acute myeloid leukemia patients in an administrative database. Pediatric Blood & Cancer 70(5): e30260, May 2023

Blinder J, Huang YS, Rossano JW, Costarino AT, Li Y: Variation in hospital costs and resource utilization after congenital heart surgery. Cardiology in the Young 33(3): 420-431, Mar 2023


Li Y, Sun L, Burstein DS, Getz K: Considerations of competing risks analysis in CardioOncology studies. JACC: CardioOncology 4(3): 287–301, Sept 2022

Li Y, Hwang WT, Maude SL, Teachey DT, Frey NV, Myers RM, Leahy AB, Liu H, Porter DL, Grupp SA, Shaw P: Statistical considerations for time-to-event endpoints in oncology clinical trials: illustrations with CAR-T immunotherapy studies. Clinical Cancer Research 28(18): 3940-3949, Sept 2022

Li Y, Izem R: Novel clinical trial design and analytic methods to tackle challenges in therapeutic development in rare diseases. Annals of Translational Medicine 10(18): 1034, Apr 2022


Bender S, Gamerman V, Reese P, Gray D, Li Y#, Shults J#: The first-order Markov conditional linear expectation approach for analysis of longitudinal data. Statistics in Medicine 40(8): 1972-1988. Apr 2021. # Equal contribution.


Li Y, Yuan Y: PA-CRM: A continuous reassessment method for pediatric phase I oncology trials with concurrent adult trials. Biometrics 76(4): 1364-1373, Dec 2020


Li Y, Newton J, Getz KD, Huang YS, Seif AE, Fisher BT, Aplenc R, Winestone LE: Comparable on-therapy mortality and supportive care requirements in black and white patients following initial induction for pediatric acute myeloid leukemia. Pediatric Blood & Cancer 66(4): e27583, Apr 2019

Li Y, Wang M, Cheung YK: Treatment and dose prioritization in early phase platform trials of targeted cancer therapies. Journal of the Royal Statistical Society: Series C (Applied Statistics) 68(2): 475-491, Feb 2019.


Mostoufi-Moab S. Sullivan L, LiVolsi V, Li Y, Beaudenon-Huibregtse S, Kazahaya K, Adzick NS, Baloch Z, Labourier E, Bauer AJ: Molecular testing for oncogenic gene alterations in pediatric thyroid lesions. Thyroid 28:60-67, 2018.

Awards and Honors

2009, Student Scholarship Award, Society for Clinical Trials

2998, Jonathan Raz Award, Biostatistics Program, University of Pennsylvania

2006, GlaxoSmithKline Scholar Award, Biostatistics Program, University of Pennsylvania

Editorial and Academic Positions

Editorial Positions

2024-Present, Statistical Advisory Panel Member, Nature Medicine

2017-Present, Editorial Board, Journal of National Cancer Institute

2015-2017, Statistical Editor, Journal of National Cancer Institute (JNCI)


2009-Present, Reviewer, Nicotine & Tobacco Research

2013-Present, Reviewer, Statistics in Medicine

2014-Present, Reviewer, Contemporary Clinical Trials

2014-Present, Reviewer, Journal of Clinical Oncology

2015-Present, Reviewer, Clinical Trials

2016-Present, Reviewer, BMC Medical Research Methodology

2017-Present, Reviewer, Communications in Statistics

2019-Present, Reviewer, Biometrika

2019-Present, Reviewer, JNCI Cancer Spectrum

2020-Present, Reviewer, Pediatrics

2020-Present, Reviewer, Cancer

2021-Present, Reviewer, BMC Pediatrics

2021-Present, Reviewer, Blood Advances

2021-Present, Reviewer, Medical Decision Making

2021-Present, Reviewer, JAMA Oncology

2021-Present, Reviewer, Nature Medicine

2022-Present, Reviewer, Nature Communications

2022-Present, Reviewer, Journal of Biopharmaceutical Statistics

2022-Present, Reviewer, SN Comprehensive Clinical Medicine

2023-Present, Reviewer, JACC CardioOncology

Academic and Institutional Committees

2010-Present, Member, Pediatric Protocol Review Committee, Division of Oncology, CHOP

2010-Present, Member, Clinical Research Quality Assurance Committee, Division of Oncology, CHOP

2013Present, Member, Division of Biostatistics Seminar Committee

2013- 2022, Member, Division of Biostatistics Junior Faculty Committee

2014, Member, Division of Biostatistics Strategic Planning Research Programs in Biostatistics

2014-2016, Chair, Division of Biostatistics Seminar Committee

2015-Present, CCEB Appointments Committee

2018-2020, Co-Chair, Division of Biostatistics Junior Faculty Committee

2019-2023, Member, Division of Biostatistics Faculty Recruitment Committee

2021-Present, Co-lead, Clinical Trials Working Group, Center for Cancer Data Science, Penn

2022-Present, Member, Division of Biostatistics Qualify Exam Committee

2023-Present, Member, The Graduate Group in Epidemiology and Biostatistics Award Committee

2024, Member, DBEI Vice Chair for Faculty Professional Development Search Committee

Leadership and Memberships

Memberships in Professional Organizations


2007-Present: Eastern North American Region (ENAR), International Biometric Society (Member)

2011-Present: International Chinese Statistical Association (ICSA) (Member)

2021: United Kingdom Medical Research Council (Grant reviewer)

2022-Present: Netherlands Organization for Health Research and Development (Grant reviewer)

2024-Present: Dutch Research Council (Grant reviewer)


2007-Present: American Statistical Association (ASA) (Member)

2011-2013: American Association for Cancer Research (Member)

2019-Present: American Society for Radiation Oncology (Resident Seed Grant reviewer)

2019, National Institute of Health (NIH), Cancer, Heart, and Sleep Epidemiology Study Sections Panel A (Grant reviewer)

2019-Present: New Approaches to Neuroblastoma Therapy (NANT) Consortium Biology Committee (Standing Member)

2020-Present: Melanoma Research Alliance (Young Investigator Award reviewer)

2021-Present:  NRG Oncology Data Monitoring Committee, (Member)

2021: National Institute of Health (NIH), Clinical Oncology Study Section (Grant reviewer)

2021-Present: Data Safety Monitoring Board (DSMB) for “Nurse AMIE: A Tablet Based Supportive Care Platform in Metastatic Breast Cancer”. PI: Kathryn Schmitz, Penn State College of Medicine (Member)

2021-2022: ASA Biometrics Section, Byar Award Committee (Member)

2022-2023: DSMB for “RAAFT-3 Trial: Radiofrequency Ablation versus Antiarrhythmic Drugs for Persistent Atrial Fibrillation”. PI: Andrea Natale, Texas Cardiac Arrhythmia Institute at St. David’s Medical Center, Austin, Texas (Member)

2022: NIH, National Institute of Neurological Disorders and Stroke (NINDS), Special Emphasis Panel/Scientific Review Group (Grant reviewer)

2022-Present Conquer Cancer, the American Society of Clinical Oncology (ASCO) Foundation, (Young Investigator Award reviewer)

2022-Present: NIH, Clinical Oncology Study Section (Standing Member)

2023-Present: Department of Defense (DOD), Congressionally Directed Medical Research Programs (CDMRP), (Grant reviewer)

2023-2024:  ICSA Annual Symposium Program Committee (Member)