Anne F. Reilly, MD, MPH

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Anne F. Reilly, MD, MPH, is medical director of Oncology and an attending physician with the Cancer Center at CHOP.

Areas of Expertise: Adolescents and young adults with cancer, Proton therapy, Non-Hodgkins lymphoma
Locations: Main Hospital

Appointments and Referrals: 1-800-TRY-CHOP (1-800-879-2467)


Anne Reilly, MD, MPH, is the medical director of the Division of Oncology at CHOP and a professor of Clinical Pediatrics at the Perelman School of Medicine at the University of Pennsylvania. Her primary areas of interest include clinical operations, care model, and quality improvement in oncology. Dr. Reilly’s clinical interests center around supportive care of children with cancer, such as prevention and treatment of infections and care of the adolescent and young adult with cancer. Her primary oncologic interests are in pediatric lymphomas and lymphoproliferative disease.

Education and Training

Medical School

MD - Jefferson Medical College of Thomas Jefferson University, Philadelphia, PA


Pediatrics - The Medical Center of Delaware, Wilmington, DE


Hematology and Oncology - The Children's Hospital of Philadelphia, Philadelphia, PA

Board Certification

Pediatric Hematology-Oncology – American Board of Pediatrics

Graduate Degree

MPH - Johns Hopkins School of Hygiene and Public Health, Baltimore, MD

Titles and Academic Titles

Medical Director, Oncology

Attending Physician

Associate Chair, Faculty Development, Department of Pediatrics

Distinguished Endowed Chair in the Department of Pediatrics

Professor of Pediatrics, Perelman School of Medicine at the University of Pennsylvania

Conditions Treated

Departments and Services

Laboratories & Research Programs

Research Topics




Freedman JL, Reilly AF, Powell SC, Bailey LC. Quality improvement initiative to increase influenza vaccination in pediatric cancer patients. Pediatrics. 2015 Feb;135(2):e540-6.  PMID: 25583919


Kesselheim JC, Atlas M, Adams D, Aygun B, Barfield R, Eisenman K, Fulbright J, Garvey K, Kersun L, Nageswara Rao A, Reilly A, Sharma M, Shereck E, Wang M, Watt T, Leavey P.  Humanism and professionalism education for pediatric hematology-oncology fellows: A model for pediatric subspecialty training.  Pediatr Blood Cancer. 2014 Oct 12.  PMID:25307425

Goodman EK, Reilly AF, Fisher BT, Fitzgerald J, Li Y, Seif AE, Huang YS, Bagatell R, Aplenc R.  Association of weekend admission with hospital length of stay, time to chemotherapy, and risk for respiratory failure in pediatric patients with newly diagnosed leukemia at freestanding US children's hospitals.  JAMA Pediatr. Oct 1;168(10):925-31, 2014. PMID  25155012

Barakat LP, Schwartz LA, Reilly A, Deatrick JA, Balis F.  A Qualitative Study of Phase III Cancer Clinical Trial Enrollment Decision-Making: Perspectives from Adolescents, Young Adults, Caregivers, and Providers. J  Adolesc Young Adult Oncol. 2014 Mar 13(1):3-11. PMID:24669354

Seif AE, Fisher BT, Li Y, Torp K, Rheam DP, Huang YS, Harris T, Shah A, Hall M, Fieldston ES, Kavcic M, Vujkovic M, Bailey LC, Kersun LS, Reilly AF, Rheingold SR, Walker DM, Aplenc R.  Patient and hospital factors associated with induction mortality in acute lymphoblastic leukemia.  Pediatr Blood Cancer 2014 May;61(5):846-52. PMID 24249480


Hill-Kayser C, Tochner Z, Both S, Lustig R, Reilly A, Balamuth N, Womer R, Maris J, Grupp S, Bagatell R. Proton versus photon radiation therapy for patients with high-risk neuroblastoma: The need for a customized approach. Pediatr Blood Cancer. Oct;60(10):1606-11. 2013 PMID 23737005

Borst AJ, States LJ, Reilly AF, Rheingold SR. Determining Response and Recurrence in Pediatric B-Cell Lymphomas of the Bone.  Pediatr Blood Cancer. Mar 20. 2013 [Epub ahead of print]  PMID: 23519982

Kersun LK, Reilly AF, Coffin SE, Sullivan KE.  Protecting pediatric oncology patients from influenza.  Oncologist. 2013;18(2):204-11. Epub Jan 31.

Kersun LS, Reilly A, Coffin SE, Boyer J, Luning Prak ET, McDonald K, Hou X,  Jawad AF,  Sullivan KE.  A prospective study of chemotherapy Immunologic effects and predictors of humoral influenza vaccine responses in a pediatric oncology cohort.  Influenza Other Respi Viruses. 2013 Nov;7(6):1158-67.PMID:23199016 




Reilly AF, Kang TI. Infections in children with cancer. In:  Brodeur, GM, Manno, CS (eds).  Requisites in Pediatrics: Hematology and Oncology.  Philadelphia, PA:  Elsevier Health Sciences-Mosby Publisher, Philadelphia, 2008


Reilly A. Infections in children with cancer. In: Shah SS (ed). Blueprints  Pediatric Infectious Diseases. Malden, MA, Blackwell Publishing, 2005.


Reilly, AF and McKenzie, S.E.: Hematology. In Pediatric Secrets, Third Edition, Polin R.A. and Ditmar, M.F., eds., Hanley and Belfus, Inc., Philadelphia, Pennsylvania, p.273-302, 2001.

Posters and Presentations

Invited Lectures


“Approach to Adenopathy”.   Second Annual Pediatric Seminar. Hospital Infantilde México Federico Gómez. Mexico City, Mexico, June 2014.

“New Approaches to Leukemia and Lymphoma”.  Division of Pediatric Hematology Oncology, American British Cowdray Hospital, Mexico City, Mexico, June 2014.


“New Therapies in Treating Childhood Cancer”, Pediatric Grand Rounds, St. Peter’s Hospital, New Brunswick, NJ, June 2013.

Awards and Honors

2014, Founding Member, Institute of Master Clinicians, Perelman School of Medicine at the University of Pennsylvania

2013, I.S. Ravdin Master Clinician Award, Perelman School of Medicine at the University of Pennsylvania

2008, Master Clinician Award, Department of Pediatrics, The Children’s Hospital of Philadelphia

2004-2009, Faculty Honor Roll, Children’s Hospital of Philadelphia

2000, Delta Omega Honor Society, Johns Hopkins School of Hygiene and Public Health

1990, Rosenblum Award, Outstanding Resident, Department of  Pediatrics, Medical Center of Delaware

1987, Hobart Hare Honor Society, Jefferson Medical College

Editorial and Academic Positions

Editorial Positions

2014-present, The Pediatric Infectious Disease Journal, ad hoc reviewer

2008-present, Pediatric Emergency Care, ad hoc reviewer

Academic and Institutional Committees

2013-present, Academic Clinician Mentoring Program, Department of Pediatrics, Chair

2012-present, Peer Review Committee, Children’s Hospital of Philadelphia, Chair

2012-2014, Ethics Committee, Children’s Hospital of Philadelphia

2012-2015, Committee on Appointments and Promotions, Perelman School of Medicine

2012-present, Academic Clinician Advisory Committee, Perelman School of Medicine

2010-present, CLABSI Prevention Steering Committee

2007-present, Leukemia/Lymphoma Steering Committee, Division of Oncology

2006-present, Chemotherapy Safety Committee, Division of Oncology

2006-present, Quality Improvement Committee, Division of Oncology, Chair

2006-present, Hematology/Oncology Fellowship Committee, Children’s Hospital of Philadelphia

2005-present, Infection Prevention and Control Committee, Children’s Hospital of Philadelphia

2005-present, Executive Committee of the Medical Staff

2005-present, Clinical Affairs Committee, Department of Pediatrics

2001-2014, Graduate Medical Education Committee, Children’s Hospital of Philadelphia

Leadership and Memberships

Memberships in Professional Organizations

Children’s Oncology Group

 - Non Hodgkin Lymphoma Committee

 - Vice Chair, ANHL01P1 study