Alix Seif Laboratory
Led by Alix E. Seif, MD, MPH, researchers in the Seif Laboratory are focused on manipulating the human innate and immune systems to treat children with acute lymphoblastic leukemia (ALL). The long-term goal of the research conducted in this laboratory is to identify innate and adaptive immune mechanisms that can be used to treat pediatric ALL more effectively, and with less toxicity, than existing therapies.
Sirolimus is effective in relapsed/refractory autoimmune cytopenias: results of a prospective multi-institutional trial. Blood. 2016 Jan 7;127(1):17-28.
Bride KL, Vincent T, Smith-Whitley K, Lambert MP, Bleesing JJ, Seif AE, Manno CS, Casper J, Grupp SA, Teachey DT.
Comparison of administrative/billing data to expected protocol-mandated chemotherapy exposure in children with acute myeloid leukemia: a report from the Children's Oncology Group. Pediatr Blood Cancer. 2015 Jul;62(7):1184-9.
Miller TP, Troxel AB, Li Y, Huang YS, Alonzo TA, Gerbing RB, Hall M, Torp K, Fisher BT, Bagatell R, Seif AE, Sung L, Gamis A, Rubin D, Luger S, Aplenc R.
Burden of influenza-related hospitalizations and attributable mortality in pediatric acute lymphoblastic leukemia. J Pediatric Infect Dis Soc. 2015 Dec;4(4):290-6.
Lee GE, Fisher BT, Xiao R, Coffin SE, Feemster K, Seif AE, Bagatell R, Li Y, Huang YSV, Aplenc R.