Kristina Cole Laboratory

Ongoing Research

Dr. Cole is contributing her expertise in molecular pathology and pediatric cancer genomics to this project performing temporal and spatial multi-omic single cell analyses from prospectively collected pediatric cancer patient specimens.

Research in the laboratory of Kristina A Cole, MD, PhD involves identifying the proteins required for malignant gliomas with alternative lengthening of telomeres (ALT) to continue to proliferate.

A clinical trial is currently underway through the COG to evaluate the safety and efficacy combining a Wee1 inhibitor AZD-1775 and Irinotecan as treatment for relapsed and refractory neuroblastoma and medulloblastoma.