Hematologic Malignancies Research News Updates
1 - 10 of 15
Pediatric Cancers Differ from Adult Cancers, and Need Different Treatment Plans, Say CHOP Experts
Published on in CHOP News
A new study finds important differences in how cancers develop in children as compared to adults, proving the concept that childhood cancers are not "small adult tumors."
T-cell Therapy Pioneered at CHOP Shows Persistent Benefits in Young Leukemia Patients
Published on in CHOP News, Cancer Connections
Updated results from a global clinical trial of the CAR T-cell therapy for ALL reveal that children and young adults continued to show high rates of durable, complete remission of their disease.
Pediatric Immunotherapy: What’s Next for CAR-T Therapy
Published on in Cancer Connections
The FDA approval of Kymriah™ has shifted the paradigm for pediatric cancer treatment — and at Children's Hospital of Philadelphia, more cell therapies are on the horizon.
FDA Committee Recommends Approving First Cell Therapy to Successfully Treat Cancer
Published on in Cancer Connections, CHOP News
The experimental, personalized cell therapy that amps up the patient's own immune system has passed a critical milestone in the path to full FDA approval.
Research on Crucial Cutting Enzyme Maps DNA Damage in Leukemias
Published on in CHOP News
A DNA-cutting enzyme that regulates gene structure has a broad role in causing certain cancers. This discovery may eventually lead to more precise treatments.
CHOP Chief of Oncology Talks about the Promise of Car T-Cell Therapy in Cancer
Published on in CHOP News
Stephen P. Hunger, MD, Chief of the Division of Oncology at CHOP talks about the evolution and promise of CAR T-cell therapies in the treatment of refractory acute lymphoblastic leukemia (ALL).
CHOP Immuno-oncology Researcher Receives Stand Up To Cancer Research Grant
Published on in CHOP News
Dr. Barrett was awarded an Innovative Research Grant from Stand Up to Cancer to help more children with leukemia have a robust response to the CAR T-cell therapy pioneered at CHOP.
In Clinical Trials, CAR T-Cell Immunotherapy Continues to Yield Complete Responses in Children & Young Adults with Relapsed and Refractory Leukemia
Published on in CHOP News
An innovative therapy using a patient’s own immune cells continues to show results in a high-risk type of acute lymphoblastic leukemia.
New Developments in Precision Medicine Therapy for Children with Acute Lymphoblastic Leukemia
Published on in Oncology Update, International Update
The Children’s Oncology Group (COG) high risk acute lymphoblastic leukemia (HR ALL) TARGET Project is a large collaborative effort led by Stephen Hunger, MD.
Younger T Cells May Improve Immunotherapy for Children’s Cancer
Published on in CHOP News
CHOP is working to improve personalized cell therapy for children. Using younger T cells may offer better results against certain types of leukemia and lymphoma.